gabapentin has been researched along with Respiratory Insufficiency in 18 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Given its faster onset, increased bioavailability and potency, and nonsaturable absorption, pregabalin's pharmacokinetics theoretically enhance its misuse liability versus gabapentin." | 2.72 | Gabapentinoid Pharmacology in the Context of Emerging Misuse Liability. ( Covvey, JR; Evoy, KE; Peckham, AM; Tidgewell, KJ, 2021) |
| " To inform their safe prescribing in older adults with chronic kidney disease (CKD), we examined the 30-day risk of serious adverse events according to the prescribed starting dose." | 1.72 | Higher-Dose Gabapentinoids and the Risk of Adverse Events in Older Adults With CKD: A Population-Based Cohort Study. ( Ahmadi, F; Blake, PG; Cowan, A; Fleet, JL; Garg, AX; Muanda, FT; Sontrop, JM; Weir, MA, 2022) |
| "Gabapentin was administered by a nasogastric tube that quickly resulted in a reversal of his symptoms." | 1.51 | Complex encephalopathy arising from the combination of opioids and gabapentin. ( Handa, R; Kak, V; Singh, H; Wasilewski, A, 2019) |
| "Gabapentin was administered by a nasogastric tube that quickly resulted in a reversal of his symptoms." | 1.51 | Complex encephalopathy arising from the combination of opioids and gabapentin. ( Handa, R; Kak, V; Singh, H; Wasilewski, A, 2019) |
| " In the dose-response analysis, moderate-dose (OR 2." | 1.46 | Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study. ( Antoniou, T; Gomes, T; Juurlink, DN; Mamdani, MM; Paterson, JM; van den Brink, W, 2017) |
| "The incidence of respiratory depression was 153 (95% confidence interval [CI], 146-161) episodes per 1000 cases." | 1.46 | Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression. ( Cavalcante, AN; Schroeder, DR; Sprung, J; Weingarten, TN, 2017) |
| "Postmorphine Paco2 was significantly higher in the amitriptyline and combination groups at all time points over the 240 min, and in the gabapentin group at 10 and 30 min after morphine injection (P<0." | 1.35 | The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits. ( Garcia-Bournissen, F; Hoshino, N; Ito, S; Kapur, B; Koren, G; Kozer, E; Leombruno, J; Levichek, Z; Taguchi, N, 2008) |
| "Quetiapine overdose is associated with coma, QTc prolongation and hypotension." | 1.31 | Massive gabapentin and presumptive quetiapine overdose. ( Cutino, L; Dunaway, MD; Spiller, HA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 7 (38.89) | 2.80 |
| Authors | Studies |
|---|---|
| Muanda, FT | 1 |
| Weir, MA | 1 |
| Ahmadi, F | 1 |
| Sontrop, JM | 1 |
| Cowan, A | 1 |
| Fleet, JL | 1 |
| Blake, PG | 1 |
| Garg, AX | 1 |
| Ghaith, S | 1 |
| Quillen, JK | 1 |
| Mead-Harvey, C | 1 |
| Buras, MR | 1 |
| Wasson, MN | 1 |
| Fernández-Liz, E | 1 |
| Barceló-Colomer, ME | 1 |
| Gómez-Ganda, L | 1 |
| Varon-Galcera, C | 1 |
| Lalueza-Broto, P | 1 |
| Medel-Rebollo, FJ | 1 |
| Hortelano-García, MA | 1 |
| Martín-Gracia, E | 1 |
| Tambon, M | 1 |
| Montarnal, B | 1 |
| Lepetit, M | 1 |
| Lapeyre-Mestre, M | 1 |
| Elleby, LM | 1 |
| Sprung, J | 3 |
| Weingarten, TN | 3 |
| Shrestha, S | 2 |
| Palaian, S | 2 |
| Evoy, KE | 1 |
| Peckham, AM | 1 |
| Covvey, JR | 1 |
| Tidgewell, KJ | 1 |
| Gomes, T | 1 |
| Juurlink, DN | 1 |
| Antoniou, T | 1 |
| Mamdani, MM | 1 |
| Paterson, JM | 1 |
| van den Brink, W | 1 |
| Deljou, A | 1 |
| Hedrick, SJ | 1 |
| Portner, ER | 1 |
| Schroeder, DR | 2 |
| Hooten, WM | 1 |
| Singh, H | 2 |
| Handa, R | 2 |
| Kak, V | 2 |
| Wasilewski, A | 2 |
| Ongley, D | 1 |
| Hayward, AK | 1 |
| Allan, C | 1 |
| Cavalcante, AN | 1 |
| Kozer, E | 1 |
| Levichek, Z | 1 |
| Hoshino, N | 1 |
| Kapur, B | 1 |
| Leombruno, J | 1 |
| Taguchi, N | 1 |
| Garcia-Bournissen, F | 1 |
| Koren, G | 1 |
| Ito, S | 1 |
| Benjaminsen, E | 1 |
| Skjeflo, GW | 1 |
| Dybwik, K | 1 |
| Salvesen, R | 1 |
| Spiller, HA | 1 |
| Dunaway, MD | 1 |
| Cutino, L | 1 |
| Batoon, SB | 1 |
| Vela, AT | 1 |
| Dave, D | 1 |
| Wahid, Z | 1 |
| Conetta, R | 1 |
| Iakovou, C | 1 |
| Banzuela, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pattern of Acute Antipsychotic Drug- Toxicity in Children at Assiut University Children Hospital[NCT06125275] | 50 participants (Anticipated) | Observational | 2023-10-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gabapentin and Respiratory Insufficiency
| Article | Year |
|---|---|
Non-opioid antinociceptive drugs : risk of respiratory depression and death related to concomitant use of gabapentinoids in addition to opioids.
Topics: Analgesics, Opioid; Cross-Sectional Studies; Gabapentin; Humans; Pregabalin; Respiratory Insufficien | 2023 |
Gabapentinoid Pharmacology in the Context of Emerging Misuse Liability.
Topics: Area Under Curve; Calcium Channel Blockers; Drug Overdose; Gabapentin; Half-Life; Humans; Metabolic | 2021 |
16 other studies available for gabapentin and Respiratory Insufficiency
| Article | Year |
|---|---|
Higher-Dose Gabapentinoids and the Risk of Adverse Events in Older Adults With CKD: A Population-Based Cohort Study.
Topics: Aged; Aged, 80 and over; Brain Diseases; Cohort Studies; Female; Gabapentin; Humans; Male; Ontario; | 2022 |
Impact of timing of preoperative gabapentin administration on postoperative somnolence.
Topics: Adult; Analgesics, Opioid; Female; Gabapentin; Humans; Pelvic Pain; Respiratory Insufficiency; Retro | 2022 |
Prevalence of Gabapentinoids and Central Nervous System Depressant Drugs, and Their Association with Risk Factors for Respiratory Depression in Primary Care Patients.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Anxiety Agents; Cross-Sectional Studies; Female; G | 2022 |
Postoperative Respiratory Depression May Be Related to Undiagnosed Sleep-Disordered Breathing or Obstructive Sleep Apnea.
Topics: Analgesics; Gabapentin; Humans; Respiratory Insufficiency; Sleep Apnea Syndromes; Sleep Apnea, Obstr | 2019 |
In brief: Respiratory depression with gabapentinoids.
Topics: Analgesics; Gabapentin; Humans; Pregabalin; Respiratory Insufficiency | 2020 |
Respiratory concerns of gabapentin and pregabalin: What does it mean to the pharmacovigilance systems in developing countries?
Topics: Analgesics; Developing Countries; Gabapentin; Humans; Pharmacovigilance; Pregabalin; Respiratory Ins | 2020 |
Respiratory concerns of gabapentin and pregabalin: What does it mean to the pharmacovigilance systems in developing countries?
Topics: Analgesics; Developing Countries; Gabapentin; Humans; Pharmacovigilance; Pregabalin; Respiratory Ins | 2020 |
Respiratory concerns of gabapentin and pregabalin: What does it mean to the pharmacovigilance systems in developing countries?
Topics: Analgesics; Developing Countries; Gabapentin; Humans; Pharmacovigilance; Pregabalin; Respiratory Ins | 2020 |
Respiratory concerns of gabapentin and pregabalin: What does it mean to the pharmacovigilance systems in developing countries?
Topics: Analgesics; Developing Countries; Gabapentin; Humans; Pharmacovigilance; Pregabalin; Respiratory Ins | 2020 |
Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study.
Topics: Adult; Aged; Amines; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studi | 2017 |
Pattern of perioperative gabapentinoid use and risk for postoperative naloxone administration.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia Recovery Period; Case-Control Stu | 2018 |
Complex encephalopathy arising from the combination of opioids and gabapentin.
Topics: Analgesics, Opioid; Brain Diseases; Chronic Pain; Gabapentin; Humans; Male; Middle Aged; Morphine; R | 2019 |
Complex encephalopathy arising from the combination of opioids and gabapentin.
Topics: Analgesics; Analgesics, Opioid; Brain Diseases; Drug Interactions; Gabapentin; Humans; Male; Middle | 2019 |
Severe respiratory depression associated with perioperative opioid-sparing gabapentin use.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Respir | 2014 |
Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression.
Topics: Adult; Aged; Amines; Analgesia; Analgesics; Analgesics, Opioid; Combined Modality Therapy; Critical | 2017 |
The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Animals; Anticonvulsants; Antidepressive Agents, Tricycli | 2008 |
A man in his seventies with prolonged myasthenic crisis.
Topics: Aged; Amines; Anti-Bacterial Agents; Antibodies, Monoclonal, Murine-Derived; Cyclohexanecarboxylic A | 2012 |
Massive gabapentin and presumptive quetiapine overdose.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antipsychotic Agents; Coma; Cyclohexanecarboxylic Acids; Dibe | 2002 |
Recurrent hypoventilation and respiratory failure during gabapentin therapy.
Topics: Acetates; Aged; Amines; Analgesics; Anti-Anxiety Agents; Anticonvulsants; Cyclohexanecarboxylic Acid | 2001 |