Page last updated: 2024-10-27

gabapentin and Reperfusion Injury

gabapentin has been researched along with Reperfusion Injury in 3 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin (GBP), an analgesic, adjunct antiepileptic, and migraine prophylactic drug, reduces neuronal injury induced by cerebral ischemia reperfusion (IR)."7.91Neuroprotective Effects of Gabapentin Against Cerebral Ischemia Reperfusion-Induced Neuronal Autophagic Injury via Regulation of the PI3K/Akt/mTOR Signaling Pathways. ( Bo, P; Cao, J; Jiang, D; Rui, Y; Su, P; Wang, J; Won, MH; Xu, P; Yan, BC; Zhu, X, 2019)
" This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury."7.77Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits. ( Börcek, AÖ; Doğulu, F; Durdağ, E; Emmez, H; Kale, A; Kılıç, N; Kurt, G; Lortlar, N; Yildirim, Z, 2011)
"Gabapentin (GBP), an analgesic, adjunct antiepileptic, and migraine prophylactic drug, reduces neuronal injury induced by cerebral ischemia reperfusion (IR)."3.91Neuroprotective Effects of Gabapentin Against Cerebral Ischemia Reperfusion-Induced Neuronal Autophagic Injury via Regulation of the PI3K/Akt/mTOR Signaling Pathways. ( Bo, P; Cao, J; Jiang, D; Rui, Y; Su, P; Wang, J; Won, MH; Xu, P; Yan, BC; Zhu, X, 2019)
" This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury."3.77Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits. ( Börcek, AÖ; Doğulu, F; Durdağ, E; Emmez, H; Kale, A; Kılıç, N; Kurt, G; Lortlar, N; Yildirim, Z, 2011)
"Mice exhibited spontaneous neuropathic pain behaviors, which were most obvious after ischemia for 5 h."1.38Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice. ( Chiang, HY; Hsieh, JH; Hsieh, ST; Lee, JE; Wang, KC, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yan, BC1
Wang, J1
Rui, Y1
Cao, J1
Xu, P1
Jiang, D1
Zhu, X1
Won, MH1
Bo, P1
Su, P1
Kale, A1
Börcek, AÖ1
Emmez, H1
Yildirim, Z1
Durdağ, E1
Lortlar, N1
Kurt, G1
Doğulu, F1
Kılıç, N1
Lee, JE1
Wang, KC1
Chiang, HY1
Hsieh, JH1
Hsieh, ST1

Other Studies

3 other studies available for gabapentin and Reperfusion Injury

ArticleYear
Neuroprotective Effects of Gabapentin Against Cerebral Ischemia Reperfusion-Induced Neuronal Autophagic Injury via Regulation of the PI3K/Akt/mTOR Signaling Pathways.
    Journal of neuropathology and experimental neurology, 2019, 02-01, Volume: 78, Issue:2

    Topics: Animals; Autophagy; Brain Ischemia; Gabapentin; Male; Neurons; Neuroprotective Agents; Oxidative Str

2019
Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits.
    Journal of neurosurgery. Spine, 2011, Volume: 15, Issue:3

    Topics: Amines; Animals; Caspase 3; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapenti

2011
Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice.
    Journal of the peripheral nervous system : JPNS, 2012, Volume: 17, Issue:3

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Femoral Artery; Gaba

2012