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gabapentin and Renal Insufficiency

gabapentin has been researched along with Renal Insufficiency in 4 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"In patients with renal failure and with decreased physiological renal clearance such as the elderly, GBP or PGB dose initiation and changes should be conservative."2.61Gabapentin or pregabalin induced myoclonus: A case series and literature review. ( Desai, A; Kherallah, Y; Marawar, R; Szabo, C, 2019)
"Gabapentin is an antiepileptic agent that is indicated for use as adjunctive therapy for partial seizures."1.30A case of sustained massive gabapentin overdose without serious side effects. ( Radtke, RA; St Clair, EW; Verma, A, 1999)
"Gabapentin CL/F and CLR were linearly correlated with creatinine clearance."1.29Pharmacokinetics of gabapentin in subjects with various degrees of renal function. ( Blum, RA; Bockbrader, H; Busch, JA; Comstock, TJ; Keller, E; Reece, PA; Reetze, P; Schultz, RW; Sica, DA; Tuerck, D, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Desai, A1
Kherallah, Y1
Szabo, C1
Marawar, R1
Hosseini-Zare, MS1
Dashti-Khavidaki, S1
Mahdavi-Mazdeh, M1
Ahmadi, F1
Akrami, S1
Blum, RA1
Comstock, TJ1
Sica, DA1
Schultz, RW1
Keller, E1
Reetze, P1
Bockbrader, H1
Tuerck, D1
Busch, JA1
Reece, PA1
Verma, A1
St Clair, EW1
Radtke, RA1

Reviews

1 review available for gabapentin and Renal Insufficiency

ArticleYear
Gabapentin or pregabalin induced myoclonus: A case series and literature review.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 61

    Topics: Adult; Aged; Analgesics; Chronic Pain; Female; Gabapentin; Humans; Male; Middle Aged; Myoclonus; Pre

2019

Other Studies

3 other studies available for gabapentin and Renal Insufficiency

ArticleYear
Peripheral neuropathy response to erythropoietin in type 2 diabetic patients with mild to moderate renal failure.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:6

    Topics: Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Ne

2012
Pharmacokinetics of gabapentin in subjects with various degrees of renal function.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:2

    Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Amines; Creatinine; Cyclohexanecarboxylic A

1994
A case of sustained massive gabapentin overdose without serious side effects.
    Therapeutic drug monitoring, 1999, Volume: 21, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Drug Overdose; Epi

1999