Page last updated: 2024-10-27

gabapentin and Pulsatile Tinnitus

gabapentin has been researched along with Pulsatile Tinnitus in 23 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" The terms used were: ("tinnitus" OR "subjective tinnitus") AND ("gabapentin")."9.22Analysis of Gabapentin's Efficacy in Tinnitus Treatment: A Systematic Review. ( Bahmad, F; Tavares, MP, 2022)
"The objective of our work is to evaluate recovery induced by gabapentin alone and in association with intradermal infiltration of lidocaine in patients affected by moderate/severe tinnitus."9.20Oral gabapentin and intradermal injection of lidocaine: is there any role in the treatment of moderate/severe tinnitus? ( Bonanno, L; Cammaroto, G; Ciodaro, F; Galletti, B; Galletti, F; Mannella, VK, 2015)
"This prospective, placebo-controlled, double-blind clinical trial evaluated the effectiveness of gabapentin in decreasing subjective features of idiopathic subjective tinnitus in the patients."9.13Gabapentin effectiveness on the sensation of subjective idiopathic tinnitus: a pilot study. ( Azarpazhooh, M; Bakhshaee, M; Ghasemi, M; Khadivi, E; Rezaei, S; Shakeri, M; Tale, M, 2008)
"This study evaluated the effectiveness of gabapentin in treating chronic tinnitus in two populations: participants with tinnitus with associated acoustic trauma and participants with tinnitus without associated acoustic trauma."9.12Effect of gabapentin on the sensation and impact of tinnitus. ( Bauer, CA; Brozoski, TJ, 2006)
"To evaluate the effectiveness of gabapentin (Neurontin) improve the disease-specific quality of life in patients with moderate tinnitus."9.12Treatment of tinnitus with gabapentin: a pilot study. ( Hannley, MT; Stinnet, S; Tucci, DL; Witsell, DL, 2007)
"To assess the therapeutic benefit of gabapentin (Neurontin) for subjective idiopathic troublesome tinnitus."9.12Relief of idiopathic subjective tinnitus: is gabapentin effective? ( Chole, RA; Finnell, J; Piccirillo, JF; Spitznagel, E; Vlahiotis, A, 2007)
"The main aim of this study was to assess the effect of gabapentin on tinnitus via a systematic review."8.87Gabapentin for tinnitus: a systematic review. ( Aazh, H; El Refaie, A; Humphriss, R, 2011)
"Typewriter tinnitus (TT) is a rare subtype of tinnitus but different in many ways, and it is treatable in most cases with carbamazepine."8.12[Typewriter tinnitus treated with gabapentin]. ( Sehested, PC, 2022)
"The objective of this article is to discuss the clinically effective use of gabapentin in patients with tinnitus."7.71Gabapentin for the treatment of tinnitus: a case report. ( Zapp, JJ, 2001)
" The terms used were: ("tinnitus" OR "subjective tinnitus") AND ("gabapentin")."5.22Analysis of Gabapentin's Efficacy in Tinnitus Treatment: A Systematic Review. ( Bahmad, F; Tavares, MP, 2022)
"The objective of our work is to evaluate recovery induced by gabapentin alone and in association with intradermal infiltration of lidocaine in patients affected by moderate/severe tinnitus."5.20Oral gabapentin and intradermal injection of lidocaine: is there any role in the treatment of moderate/severe tinnitus? ( Bonanno, L; Cammaroto, G; Ciodaro, F; Galletti, B; Galletti, F; Mannella, VK, 2015)
"This prospective, placebo-controlled, double-blind clinical trial evaluated the effectiveness of gabapentin in decreasing subjective features of idiopathic subjective tinnitus in the patients."5.13Gabapentin effectiveness on the sensation of subjective idiopathic tinnitus: a pilot study. ( Azarpazhooh, M; Bakhshaee, M; Ghasemi, M; Khadivi, E; Rezaei, S; Shakeri, M; Tale, M, 2008)
"This study evaluated the effectiveness of gabapentin in treating chronic tinnitus in two populations: participants with tinnitus with associated acoustic trauma and participants with tinnitus without associated acoustic trauma."5.12Effect of gabapentin on the sensation and impact of tinnitus. ( Bauer, CA; Brozoski, TJ, 2006)
"To evaluate the effectiveness of gabapentin (Neurontin) improve the disease-specific quality of life in patients with moderate tinnitus."5.12Treatment of tinnitus with gabapentin: a pilot study. ( Hannley, MT; Stinnet, S; Tucci, DL; Witsell, DL, 2007)
"To assess the therapeutic benefit of gabapentin (Neurontin) for subjective idiopathic troublesome tinnitus."5.12Relief of idiopathic subjective tinnitus: is gabapentin effective? ( Chole, RA; Finnell, J; Piccirillo, JF; Spitznagel, E; Vlahiotis, A, 2007)
"Vestibular paroxysmia is defined as paroxysmal, brief, and carbamazepine-responsive vertigo."4.89Vestibular paroxysmia associated with paroxysmal pulsatile tinnitus: a case report and review of the literature. ( Chang, TP; Hsu, YC; Wu, YC, 2013)
"The main aim of this study was to assess the effect of gabapentin on tinnitus via a systematic review."4.87Gabapentin for tinnitus: a systematic review. ( Aazh, H; El Refaie, A; Humphriss, R, 2011)
"Typewriter tinnitus (TT) is a rare subtype of tinnitus but different in many ways, and it is treatable in most cases with carbamazepine."4.12[Typewriter tinnitus treated with gabapentin]. ( Sehested, PC, 2022)
" We describe two patients with brief, spontaneous, recurrent attacks of tinnitus and vertigo that responded to low dose gabapentin and we argue that this clinical presentation represents the prototypical 8th nerve vascular compression syndrome."3.75Gabapentin responsive audiovestibular paroxysmia. ( Baloh, RW; Russell, D, 2009)
"The objective of this article is to discuss the clinically effective use of gabapentin in patients with tinnitus."3.71Gabapentin for the treatment of tinnitus: a case report. ( Zapp, JJ, 2001)
"Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation."2.47Anticonvulsants for tinnitus. ( Hoekstra, CE; Rovers, MM; Rynja, SP; van Zanten, GA, 2011)
"Tinnitus affects approximately 50 million people in the USA alone, with 10 million being highly debilitated."1.37An in vitro model for testing drugs to treat tinnitus. ( Gopal, K; Gross, GW; Lukas, TJ; Moore, EJ; Wu, C, 2011)
"Subjective tinnitus is a common and often debilitating disorder that is difficult to study because it is a perceptual state without an objective stimulus correlate."1.31Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model. ( Bauer, CA; Brozoski, TJ, 2001)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (56.52)29.6817
2010's8 (34.78)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Sehested, PC1
Tavares, MP1
Bahmad, F1
Chang, TP1
Wu, YC1
Hsu, YC1
Ciodaro, F1
Mannella, VK1
Cammaroto, G1
Bonanno, L1
Galletti, F1
Galletti, B1
Bauer, CA4
Berry, J1
Brozoski, TJ4
Shulman, A2
Russell, D1
Baloh, RW1
Dehkordi, MA1
Abolbashari, S1
Taheri, R1
Einolghozati, S1
Wu, C1
Gopal, K1
Gross, GW1
Lukas, TJ1
Moore, EJ1
Hoekstra, CE1
Rynja, SP1
van Zanten, GA1
Rovers, MM1
Chen, WH1
Yin, HL1
Aazh, H1
El Refaie, A1
Humphriss, R1
Strashun, AM1
Goldstein, BA1
Kanashiro, AM1
Alexandre, PL1
Pereira, CB1
Melo, AC1
Scaff, M1
Witsell, DL1
Hannley, MT1
Stinnet, S1
Tucci, DL1
Snow, JB1
Bahmad, FM1
Venosa, AR1
Oliveira, CA1
Piccirillo, JF1
Finnell, J1
Vlahiotis, A1
Chole, RA1
Spitznagel, E1
Bakhshaee, M1
Ghasemi, M1
Azarpazhooh, M1
Khadivi, E1
Rezaei, S1
Shakeri, M1
Tale, M1
Zapp, JJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treating Tinnitus Using the Neuromonics Tinnitus Treatment Program: A Randomized, Double-blind Study[NCT02829073]120 participants (Anticipated)Interventional2016-04-30Recruiting
Gabapentin for the Relief of Idiopathic Subjective Tinnitus[NCT00317850]Phase 2/Phase 3160 participants Interventional2004-04-30Terminated
Phase 2 Effect of Gabapentin on Idiopathic Subjective Tinnitus[NCT00555776]Phase 270 participants (Anticipated)Interventional2007-01-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for gabapentin and Pulsatile Tinnitus

ArticleYear
Analysis of Gabapentin's Efficacy in Tinnitus Treatment: A Systematic Review.
    The Annals of otology, rhinology, and laryngology, 2022, Volume: 131, Issue:3

    Topics: Administration, Oral; Excitatory Amino Acid Antagonists; Gabapentin; Humans; Tinnitus

2022
Vestibular paroxysmia associated with paroxysmal pulsatile tinnitus: a case report and review of the literature.
    Acta neurologica Taiwanica, 2013, Volume: 22, Issue:2

    Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobu

2013
Anticonvulsants for tinnitus.
    The Cochrane database of systematic reviews, 2011, Jul-06, Issue:7

    Topics: Administration, Oral; Amines; Anticonvulsants; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic

2011
Gabapentin for tinnitus: a systematic review.
    American journal of audiology, 2011, Volume: 20, Issue:2

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hearing L

2011
Strategies of the Tinnitus Research Consortium.
    Acta oto-laryngologica. Supplementum, 2006, Issue:556

    Topics: Amines; Analgesics; Biomedical Research; Consensus; Cyclohexanecarboxylic Acids; Electric Stimulatio

2006
Gabapentin.
    Progress in brain research, 2007, Volume: 166

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-A

2007

Trials

7 trials available for gabapentin and Pulsatile Tinnitus

ArticleYear
Oral gabapentin and intradermal injection of lidocaine: is there any role in the treatment of moderate/severe tinnitus?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:10

    Topics: Administration, Oral; Adult; Amines; Anesthetics, Local; Anticonvulsants; Cyclohexanecarboxylic Acid

2015
Efficacy of gabapentin on subjective idiopathic tinnitus: a randomized, double-blind, placebo-controlled trial.
    Ear, nose, & throat journal, 2011, Volume: 90, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Doubl

2011
Effect of gabapentin on the sensation and impact of tinnitus.
    The Laryngoscope, 2006, Volume: 116, Issue:5

    Topics: Adolescent; Adult; Aged; Amines; Audiometry; Cyclohexanecarboxylic Acids; Dose-Response Relationship

2006
Treatment of tinnitus with gabapentin: a pilot study.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2007, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Auditory Threshold; Cyclohexanecarbo

2007
Benzodiazepines and GABAergics in treating severe disabling tinnitus of predominantly cochlear origin.
    The international tinnitus journal, 2006, Volume: 12, Issue:2

    Topics: Adult; Amines; Benzodiazepines; Clonazepam; Cochlear Diseases; Cyclohexanecarboxylic Acids; Disabili

2006
Relief of idiopathic subjective tinnitus: is gabapentin effective?
    Archives of otolaryngology--head & neck surgery, 2007, Volume: 133, Issue:4

    Topics: Adolescent; Adult; Aged; Amines; Calcium Channel Blockers; Chi-Square Distribution; Cyclohexanecarbo

2007
Gabapentin effectiveness on the sensation of subjective idiopathic tinnitus: a pilot study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2008, Volume: 265, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory

2008

Other Studies

10 other studies available for gabapentin and Pulsatile Tinnitus

ArticleYear
[Typewriter tinnitus treated with gabapentin].
    Ugeskrift for laeger, 2022, 08-15, Volume: 184, Issue:33

    Topics: Adult; Carbamazepine; Female; Gabapentin; Humans; Nerve Compression Syndromes; Tinnitus; Vertigo

2022
Clinical trials supported by the Tinnitus Research Consortium: Lessons learned, the Southern Illinois University experience.
    Hearing research, 2016, Volume: 334

    Topics: Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2016
Gabapentin and tinnitus relief.
    The international tinnitus journal, 2008, Volume: 14, Issue:1

    Topics: Amines; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; g

2008
Gabapentin responsive audiovestibular paroxysmia.
    Journal of the neurological sciences, 2009, Jun-15, Volume: 281, Issue:1-2

    Topics: Aged, 80 and over; Amines; Central Nervous System Agents; Cranial Nerve Diseases; Cyclohexanecarboxy

2009
An in vitro model for testing drugs to treat tinnitus.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Amines; Animals; Antioxidants; Calcium Channel Blockers; Carnitine; Convulsants; Cyclohexanecarboxyl

2011
Successful amelioration of tinnitus in a stroke patient by low-dose gabapentin.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2012, Volume: 21, Issue:8

    Topics: Amines; Audiometry, Pure-Tone; Basal Ganglia Hemorrhage; Cerebral Angiography; Cyclohexanecarboxylic

2012
GABAA-benzodiazepine-chloride receptor-targeted therapy for tinnitus control: preliminary report.
    The international tinnitus journal, 2002, Volume: 8, Issue:1

    Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Benzodiazepines; Chloride Channels; Clonazepam; Cy

2002
[Vestibular paroxysmia: clinical study and treatment of eight patients].
    Arquivos de neuro-psiquiatria, 2005, Volume: 63, Issue:3A

    Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma

2005
Gabapentin for the treatment of tinnitus: a case report.
    Ear, nose, & throat journal, 2001, Volume: 80, Issue:2

    Topics: Acetates; Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic;

2001
Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model.
    Journal of the Association for Research in Otolaryngology : JARO, 2001, Volume: 2, Issue:1

    Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Deafness; Diagnosis, Differential; Disease M

2001