Page last updated: 2024-10-27

gabapentin and Prostatic Neoplasms

gabapentin has been researched along with Prostatic Neoplasms in 7 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"Via a prospective, double-blind, placebo-controlled clinical trial, men with hot flashes, on a stable androgen deprivation therapy program for prostate cancer, received a placebo or gabapentin at target doses of 300, 600, or 900 mg/day."9.14A phase III randomized, double-blind, placebo-controlled trial of gabapentin in the management of hot flashes in men (N00CB). ( Atherton, PJ; Barton, DL; Bearden, JD; Dueck, AC; Fitch, TR; Jafar, S; Khoyratty, BS; Knutson, WH; Kottschade, L; Loprinzi, CL; Marsa, GW; Rowland, KM, 2009)
"To report a case of successful treatment of refractory hot flashes with gabapentin in a patient with prostate cancer who was receiving combination antiandrogen and gonadotropin hormone-releasing hormone (GnRH) analog therapy."7.71Gabapentin for hot flashes in prostate cancer. ( Jeffery, SM; Pepe, JJ; Popovich, LM; Vitagliano, G, 2002)
"Via a prospective, double-blind, placebo-controlled clinical trial, men with hot flashes, on a stable androgen deprivation therapy program for prostate cancer, received a placebo or gabapentin at target doses of 300, 600, or 900 mg/day."5.14A phase III randomized, double-blind, placebo-controlled trial of gabapentin in the management of hot flashes in men (N00CB). ( Atherton, PJ; Barton, DL; Bearden, JD; Dueck, AC; Fitch, TR; Jafar, S; Khoyratty, BS; Knutson, WH; Kottschade, L; Loprinzi, CL; Marsa, GW; Rowland, KM, 2009)
"To report a case of successful treatment of refractory hot flashes with gabapentin in a patient with prostate cancer who was receiving combination antiandrogen and gonadotropin hormone-releasing hormone (GnRH) analog therapy."3.71Gabapentin for hot flashes in prostate cancer. ( Jeffery, SM; Pepe, JJ; Popovich, LM; Vitagliano, G, 2002)
"The breadth of literature for the treatment of hot flashes is much smaller in men than that in women."2.48Androgen deprivation therapy-associated vasomotor symptoms. ( Jones, JM; Kohli, M; Loprinzi, CL, 2012)
"Women treated for breast cancer and men receiving androgen ablation for prostate cancer experience hot flushes that are more frequent, severe and longer lasting than those experienced by the general menopausal population."2.43Treatment of hot flushes in breast and prostate cancer. ( Adelson, KB; Hershman, DL; Loprinzi, CL, 2005)
"5 mg/d, are reasonable initial dosages, and if symptoms do not improve within a week or two, the dosage can be doubled."2.42Management of hot flashes in breast cancer survivors and men with prostate cancer. ( Stearns, V, 2004)
"The Dunning rat model of prostate cancer was used."1.43Gabapentin, an Analgesic Used Against Cancer-Associated Neuropathic Pain: Effects on Prostate Cancer Progression in an In Vivo Rat Model. ( Altun, S; Bugan, I; Djamgoz, MB; Karagoz, Z, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bugan, I1
Karagoz, Z1
Altun, S1
Djamgoz, MB1
Loprinzi, CL3
Dueck, AC1
Khoyratty, BS1
Barton, DL1
Jafar, S1
Rowland, KM1
Atherton, PJ1
Marsa, GW1
Knutson, WH1
Bearden, JD1
Kottschade, L1
Fitch, TR1
Jones, JM1
Kohli, M1
Lefkowits, CC1
Arnold, RM1
Stearns, V1
Adelson, KB1
Hershman, DL1
Jeffery, SM1
Pepe, JJ1
Popovich, LM1
Vitagliano, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III Randomized, Double-Blind, Placebo-Controlled Trial of Gabapentin in the Management of Hot Flashes in Men[NCT00028574]Phase 3223 participants (Actual)Interventional2001-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for gabapentin and Prostatic Neoplasms

ArticleYear
Androgen deprivation therapy-associated vasomotor symptoms.
    Asian journal of andrology, 2012, Volume: 14, Issue:2

    Topics: Amines; Androgen Antagonists; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; F

2012
Management of hot flashes in breast cancer survivors and men with prostate cancer.
    Current oncology reports, 2004, Volume: 6, Issue:4

    Topics: Amines; Anti-Anxiety Agents; Breast Neoplasms; Complementary Therapies; Contraceptives, Oral, Synthe

2004
Treatment of hot flushes in breast and prostate cancer.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:7

    Topics: Amines; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cimicifuga; Contraindications; Cyclohexan

2005

Trials

1 trial available for gabapentin and Prostatic Neoplasms

ArticleYear
A phase III randomized, double-blind, placebo-controlled trial of gabapentin in the management of hot flashes in men (N00CB).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:3

    Topics: Aged; Aged, 80 and over; Amines; Androgen Antagonists; Cyclohexanecarboxylic Acids; Dose-Response Re

2009

Other Studies

3 other studies available for gabapentin and Prostatic Neoplasms

ArticleYear
Gabapentin, an Analgesic Used Against Cancer-Associated Neuropathic Pain: Effects on Prostate Cancer Progression in an In Vivo Rat Model.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:3

    Topics: Amines; Analgesics; Animals; Carcinogenesis; Cells, Cultured; Cyclohexanecarboxylic Acids; Disease M

2016
Hot flashes in palliative care. Part 2 #262.
    Journal of palliative medicine, 2013, Volume: 16, Issue:1

    Topics: Amines; Analgesics; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clonidine; Cyclohexanecarboxy

2013
Gabapentin for hot flashes in prostate cancer.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:3

    Topics: Acetates; Aged; Amines; Androgen Antagonists; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Ant

2002