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gabapentin and Porphyria, Acute Intermittent

gabapentin has been researched along with Porphyria, Acute Intermittent in 7 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.

Research Excerpts

ExcerptRelevanceReference
" Gabapentin is a new antiepileptic drug not appreciably metabolized by the liver in humans, and it appears to be safe and effective in the maintenance therapy of epilepsy in these patients."3.70Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin. ( Brambilla, A; Erli, LC; Grandi, R; Mirabile, D; Zadra, M, 1998)
"Gabapentin was prescribed for the control of seizure and pain before the diagnosis of acute intermittent porphyria was confirmed."1.36Gabapentin reduces neurovisceral pain of porphyria. ( Chen, JT; Liao, KK; Lin, CY; Lin, YY; Niu, DM; Tsao, YC, 2010)
"The patient was initially treated for her abdominal pain and vomiting."1.35Drug use in porphyria: a therapeutic dilemma. ( Jimmy, B; Jose, J; Saravu, K; Shastry, BA, 2008)
"Gabapentin is a new AED not appreciably metabolized by the liver in humans."1.29Gabapentin treatment of seizures in acute intermittent porphyria. ( Tatum, WO; Zachariah, SB, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, TC1
Lai, SL1
Hsu, SP1
Ro, LS1
Jose, J1
Saravu, K1
Shastry, BA1
Jimmy, B1
Tsao, YC1
Niu, DM1
Chen, JT1
Lin, CY1
Lin, YY1
Liao, KK1
Bhatia, R1
Vibha, D1
Srivastava, MV1
Prasad, K1
Tripathi, M1
Bhushan Singh, M1
Tatum, WO1
Zachariah, SB1
Zadra, M1
Grandi, R1
Erli, LC1
Mirabile, D1
Brambilla, A1
Arora, A1
Mahajan, V1

Other Studies

7 other studies available for gabapentin and Porphyria, Acute Intermittent

ArticleYear
Treatment of neuropathic pain in acute intermittent porphyria with gabapentin.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2013, Volume: 112, Issue:9

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid;

2013
Drug use in porphyria: a therapeutic dilemma.
    Singapore medical journal, 2008, Volume: 49, Issue:10

    Topics: Abdominal Pain; Adult; Amines; Anticonvulsants; Antiemetics; Antihypertensive Agents; Chest Pain; Cy

2008
Gabapentin reduces neurovisceral pain of porphyria.
    Acta neurologica Taiwanica, 2010, Volume: 19, Issue:2

    Topics: Abdomen, Acute; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin;

2010
Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
    Epilepsia, 2008, Volume: 49, Issue:5

    Topics: Amines; Anesthetics, Intravenous; Anticonvulsants; Child; Comorbidity; Cyclohexanecarboxylic Acids;

2008
Gabapentin treatment of seizures in acute intermittent porphyria.
    Neurology, 1995, Volume: 45, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-A

1995
Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
    Seizure, 1998, Volume: 7, Issue:5

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin;

1998
Gabapentin in seizures due to acute intermittent porphyria.
    Neurology India, 2000, Volume: 48, Issue:2

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami

2000