Page last updated: 2024-10-27

gabapentin and Polyneuropathies

gabapentin has been researched along with Polyneuropathies in 13 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin is an effective option for the treatment of neuropathic pain syndromes because of its efficacy and favorable side-effect profile."3.70Gabapentin induced polyneuropathy. ( Gould, HJ, 1998)
"Asterixis has been reported as a side effect of toxic and metabolic abnormalities."2.49Asterixis related to gabapentin intake: a case report and review. ( Wahba, M; Waln, O, 2013)
"Gabapentin was effective in transiently reversing mechanical allodynia in those mice with lowered thresholds."1.42Differences in cisplatin-induced mechanical allodynia in male and female mice. ( Corr, M; Woller, SA; Yaksh, TL, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's7 (53.85)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Callaghan, BC1
Price, RS1
Feldman, EL1
Iravani, S1
Kazemi Motlagh, AH1
Emami Razavi, SZ1
Shahi, F1
Wang, J1
Hou, L1
Sun, W1
Afshari Fard, MR1
Aghili, M1
Karimi, M1
Rezaeizadeh, H1
Zhao, B1
Wahba, M1
Waln, O1
Huehnchen, P1
Boehmerle, W1
Endres, M1
Katamonova, EV1
Nurbaeva, DZh1
Lakhman, OL2
Kasyanovskaya, VP1
Woller, SA1
Corr, M1
Yaksh, TL1
van Spijker, RC1
Monasch, E1
Compier-Mahboob, N1
Merkies, IS1
Kempler, P1
Kartapol'tseva, NV1
Rusanova, DV1
Shahan, JL1
Panu, LD1
Hildebrandt, GC1
Braune, S1
Gould, HJ1
Peña, D1
Prada, JL1
de La Torre, J1
del Arco, A1
García-Alegría, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy of Social Media Assisted Home-based Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated With Chemotherapy Induced Peripheral Neuropathy in Patients With Breast Cancer[NCT05904340]86 participants (Anticipated)Interventional2023-07-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for gabapentin and Polyneuropathies

ArticleYear
Distal Symmetric Polyneuropathy in 2020.
    JAMA, 2020, 07-07, Volume: 324, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Diabetic Neuropathies; Gabapentin; H

2020
Asterixis related to gabapentin intake: a case report and review.
    Postgraduate medicine, 2013, Volume: 125, Issue:5

    Topics: Aged; Amines; Cyclohexanecarboxylic Acids; Dyskinesias; Gabapentin; gamma-Aminobutyric Acid; Humans;

2013
[Evidence-based pharmacotherapy of neuropathic pain syndromes].
    MMW Fortschritte der Medizin, 2004, Dec-09, Volume: 146, Issue:50

    Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Antioxidants; Cyclohexanec

2004
[Gabapentin in the treatment of polyneuropathy associated with the human immunodeficiency virus].
    Enfermedades infecciosas y microbiologia clinica, 1999, Volume: 17, Issue:10

    Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric

1999

Trials

3 trials available for gabapentin and Polyneuropathies

ArticleYear
Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial.
    Pain research & management, 2020, Volume: 2020

    Topics: Acupuncture Therapy; Adult; Analgesics; Antineoplastic Agents; China; Female; Gabapentin; Humans; Ir

2020
[Diagnosis and treatment of polyneuropathy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014, Volume: 114, Issue:1

    Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Extremities; Gabapentin; gamma-Aminobutyric Acid; Hand-A

2014
[Efficacy of gabapentin in the treatment of professional polyneuropathy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:1

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electromyography; Gabapentin; gamma-Aminobutyr

2011

Other Studies

6 other studies available for gabapentin and Polyneuropathies

ArticleYear
Assessment of paclitaxel induced sensory polyneuropathy with "Catwalk" automated gait analysis in mice.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Amines; Animals; Antineoplastic Agents; Automation; Cyclohexanecarboxylic Acids; Dose-Response Relat

2013
Differences in cisplatin-induced mechanical allodynia in male and female mice.
    European journal of pain (London, England), 2015, Volume: 19, Issue:10

    Topics: Amines; Analgesics; Animals; Antineoplastic Agents; Cisplatin; Cyclohexanecarboxylic Acids; Disease

2015
[Neurological symptoms following lightening strike].
    Nederlands tijdschrift voor geneeskunde, 2009, Volume: 153

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lightn

2009
[Treatment of neuropathies].
    Orvosi hetilap, 2010, Jan-10, Volume: 151, Issue:2

    Topics: Adjuvants, Immunologic; Adrenergic Uptake Inhibitors; Amines; Analgesics; Antioxidants; Capsaicin; C

2010
Rhabdomyolysis in a multiple myeloma patient secondary to concurrent treatment with lenalidomide and pravastatin and to lenalidomide alone.
    International journal of hematology, 2012, Volume: 96, Issue:6

    Topics: Amines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Boronic Acids; Bortezomib; Combi

2012
Gabapentin induced polyneuropathy.
    Pain, 1998, Volume: 74, Issue:2-3

    Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Huma

1998