Page last updated: 2024-10-27

gabapentin and Panic Disorder

gabapentin has been researched along with Panic Disorder in 6 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research Excerpts

ExcerptRelevanceReference
"A randomized, double-blind, placebo-controlled, parallel-group study was conducted to evaluate the efficacy and safety of gabapentin in relieving the symptoms of panic disorder."9.09Placebo-controlled study of gabapentin treatment of panic disorder. ( Chouinard, G; Crockatt, J; Dager, SR; Greiner, M; Lydiard, RB; Pande, AC; Pollack, MH; Shiovitz, T; Taylor, CB, 2000)
"A randomized, double-blind, placebo-controlled, parallel-group study was conducted to evaluate the efficacy and safety of gabapentin in relieving the symptoms of panic disorder."5.09Placebo-controlled study of gabapentin treatment of panic disorder. ( Chouinard, G; Crockatt, J; Dager, SR; Greiner, M; Lydiard, RB; Pande, AC; Pollack, MH; Shiovitz, T; Taylor, CB, 2000)
"Six subjects with panic disorder underwent sodium lactate infusions in conjunction with magnetic resonance spectroscopic imaging (MRSI) at study entrance when actively symptomatic and after clinical improvement while under treatment with gabapentin."5.09Brain metabolic changes during lactate-induced panic: effects of gabapentin treatment. ( Dager, SR; Friedman, SD; Layton, ME, 2001)
"Pharmacologic treatments for panic disorder and social phobia have been available since the early 1960s."2.40Panic disorder and social phobia: current treatments and new strategies. ( Connor, KM; Davidson, JR; Sutherland, SM, 1998)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Joos, AA1
Zeeck, A1
Himmerich, H1
Nickel, T1
Dalal, MA1
Müller, MB1
Pollack, MH2
Matthews, J1
Scott, EL1
Pande, AC1
Crockatt, J1
Greiner, M1
Chouinard, G1
Lydiard, RB1
Taylor, CB1
Dager, SR2
Shiovitz, T1
Layton, ME1
Friedman, SD1
Davidson, JR1
Connor, KM1
Sutherland, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy[NCT05024825]Phase 417 participants (Actual)Interventional2017-08-04Terminated (stopped due to recruitment target not met.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gabapentin and Panic Disorder

ArticleYear
Panic disorder and social phobia: current treatments and new strategies.
    Cleveland Clinic journal of medicine, 1998, Volume: 65 Suppl 1

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Cycl

1998

Trials

2 trials available for gabapentin and Panic Disorder

ArticleYear
Placebo-controlled study of gabapentin treatment of panic disorder.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:4

    Topics: Acetates; Adolescent; Adult; Aged; Agoraphobia; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic A

2000
Brain metabolic changes during lactate-induced panic: effects of gabapentin treatment.
    Depression and anxiety, 2001, Volume: 14, Issue:4

    Topics: Acetates; Adult; Amines; Arousal; Aspartic Acid; Brain; Cyclohexanecarboxylic Acids; Double-Blind Me

2001

Other Studies

3 other studies available for gabapentin and Panic Disorder

ArticleYear
Gabapentin in somatoform and panic disorder.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:1

    Topics: Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Human

2013
[Gabapentin treatment in a female patient with panic disorder and adverse effects under carbamazepine during benzodiazepine withdrawal].
    Psychiatrische Praxis, 2007, Volume: 34, Issue:2

    Topics: Aged; Alprazolam; Amines; Antimanic Agents; Benzodiazepines; Carbamazepine; Chemical and Drug Induce

2007
Gabapentin as a potential treatment for anxiety disorders.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids

1998