Page last updated: 2024-10-27

gabapentin and Pancreatic Neoplasms

gabapentin has been researched along with Pancreatic Neoplasms in 4 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
" Male Wistar rats fed with 2% gabapentin (1-(aminomethyl)cyclohexane acetic acid) in diet for 2 years developed pancreatic exocrine adenomas and adenocarcinomas."3.69Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin. ( de la Iglesia, FA; Fowler, ML; Lalwani, ND; Reddy, JK; Sigler, RE, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pelham, A1
Lee, MA1
Regnard, CB1
Porzio, G1
Aielli, F1
Narducci, F1
Varrassi, G1
Ricevuto, E1
Ficorella, C1
Marchetti, P1
Sigler, RE2
Gough, AW1
de la Iglesia, FA2
Fowler, ML1
Reddy, JK1
Lalwani, ND1

Other Studies

4 other studies available for gabapentin and Pancreatic Neoplasms

ArticleYear
Gabapentin for coeliac plexus pain.
    Palliative medicine, 2002, Volume: 16, Issue:4

    Topics: Acetates; Aged; Amines; Analgesics; Celiac Plexus; Cyclohexanecarboxylic Acids; Female; Gabapentin;

2002
Hiccup in patients with advanced cancer successfully treated with gabapentin: report of three cases.
    The New Zealand medical journal, 2003, Sep-26, Volume: 116, Issue:1182

    Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Neoplasms; Carcinoma, Small Cell; Colonic Neoplasms;

2003
Pancreatic acinar cell neoplasia in male Wistar rats following 2 years of gabapentin exposure.
    Toxicology, 1995, Apr-12, Volume: 98, Issue:1-3

    Topics: Acetates; Adenoma; Amines; Animals; Anticonvulsants; Carcinoma, Acinar Cell; Cyclohexanecarboxylic A

1995
Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin.
    Mutation research, 1995, Volume: 327, Issue:1-2

    Topics: Acetates; Adenocarcinoma; Adenoma; Amines; Animals; Base Sequence; Codon; Cyclohexanecarboxylic Acid

1995