gabapentin has been researched along with Nerve Degeneration in 4 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Robust allodynia was observed in all three ligation groups." | 1.42 | Ligation of mouse L4 and L5 spinal nerves produces robust allodynia without major motor function deficit. ( Baker, KB; Lanthorn, TH; Mason, S; Rajan, I; Savelieva, KV; Vogel, P; Ye, GL, 2015) |
| "Koumine treatment of diabetic rats decreased neuropathic pain behavior as early as after the first administration." | 1.40 | Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy. ( Huang, HH; Ling, Q; Liu, M; Wu, MX; Xu, Y; Yang, J; Yu, CX, 2014) |
| "Mice exhibited spontaneous neuropathic pain behaviors, which were most obvious after ischemia for 5 h." | 1.38 | Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice. ( Chiang, HY; Hsieh, JH; Hsieh, ST; Lee, JE; Wang, KC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ye, GL | 1 |
| Savelieva, KV | 1 |
| Vogel, P | 1 |
| Baker, KB | 1 |
| Mason, S | 1 |
| Lanthorn, TH | 1 |
| Rajan, I | 1 |
| Ling, Q | 1 |
| Liu, M | 1 |
| Wu, MX | 1 |
| Xu, Y | 1 |
| Yang, J | 1 |
| Huang, HH | 1 |
| Yu, CX | 1 |
| Reda, HM | 1 |
| Zaitone, SA | 1 |
| Moustafa, YM | 1 |
| Lee, JE | 1 |
| Wang, KC | 1 |
| Chiang, HY | 1 |
| Hsieh, JH | 1 |
| Hsieh, ST | 1 |
4 other studies available for gabapentin and Nerve Degeneration
| Article | Year |
|---|---|
Ligation of mouse L4 and L5 spinal nerves produces robust allodynia without major motor function deficit.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Amin | 2015 |
Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy.
Topics: Amines; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experim | 2014 |
Effect of levetiracetam versus gabapentin on peripheral neuropathy and sciatic degeneration in streptozotocin-diabetic mice: Influence on spinal microglia and astrocytes.
Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetes | 2016 |
Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Femoral Artery; Gaba | 2012 |