Page last updated: 2024-10-27

gabapentin and Myasthenia Gravis

gabapentin has been researched along with Myasthenia Gravis in 4 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research Excerpts

ExcerptRelevanceReference
" In order to avoid drug interactions as well as adverse effects of carbamazepine in myasthenia gravis, gabapentin was chosen for the treatment of neuropathic pain."7.72Treatment of post-herpetic pain in myasthenia gravis: exacerbation of weakness due to gabapentin. ( Beuche, W; Scheschonka, A, 2003)
" In order to avoid drug interactions as well as adverse effects of carbamazepine in myasthenia gravis, gabapentin was chosen for the treatment of neuropathic pain."3.72Treatment of post-herpetic pain in myasthenia gravis: exacerbation of weakness due to gabapentin. ( Beuche, W; Scheschonka, A, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sheen, VL1
Ohaegbulam, C1
Rencus, T1
Tandon, D1
Benjaminsen, E1
Skjeflo, GW1
Dybwik, K1
Salvesen, R1
Scheschonka, A1
Beuche, W1
Boneva, N1
Brenner, T1
Argov, Z1

Other Studies

4 other studies available for gabapentin and Myasthenia Gravis

ArticleYear
Gabapentin-induced exacerbation of myasthenia gravis.
    Muscle & nerve, 2010, Volume: 42, Issue:1

    Topics: Aged; Amines; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagoni

2010
A man in his seventies with prolonged myasthenic crisis.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Oct-16, Volume: 132, Issue:19

    Topics: Aged; Amines; Anti-Bacterial Agents; Antibodies, Monoclonal, Murine-Derived; Cyclohexanecarboxylic A

2012
Treatment of post-herpetic pain in myasthenia gravis: exacerbation of weakness due to gabapentin.
    Pain, 2003, Volume: 104, Issue:1-2

    Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Z

2003
Gabapentin may be hazardous in myasthenia gravis.
    Muscle & nerve, 2000, Volume: 23, Issue:8

    Topics: Acetates; Action Potentials; Aged; Amines; Animals; Anticonvulsants; Autoantibodies; Cholinesterase

2000