Page last updated: 2024-10-27

gabapentin and Muscle Cramp

gabapentin has been researched along with Muscle Cramp in 6 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Muscle Cramp: A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398)

Research Excerpts

ExcerptRelevanceReference
"At a dose of 400mg orally three times a day, gabapentin may be of value in the treatment of the spasticity and painful muscle cramping experienced by patients with multiple sclerosis."9.08Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis. ( Gruenthal, M; Mueller, ME; Olson, WH; Olson, WL, 1997)
"Selection and extraction: a MEDLINE/PubMed, English-language literature search from 1966 to the present using quinine, leg cramps, vitamin E, verapamil, muscle relaxants, gabapentin as search terms."8.84Are there alternatives to the use of quinine to treat nocturnal leg cramps? ( Guay, DR, 2008)
" Gabapentin therapy proved to be very satisfactory in relieving muscular cramps with a relatively low dosage (600 mg/day) and without any remarkable side effects."5.30A case of myokymia-cramp syndrome successfully treated with gabapentin. ( Cardinali, P; Parisi, L; Pierelli, F; Rossi, P; Serrao, M; Tramutoli, R, 1998)
"At a dose of 400mg orally three times a day, gabapentin may be of value in the treatment of the spasticity and painful muscle cramping experienced by patients with multiple sclerosis."5.08Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis. ( Gruenthal, M; Mueller, ME; Olson, WH; Olson, WL, 1997)
"Selection and extraction: a MEDLINE/PubMed, English-language literature search from 1966 to the present using quinine, leg cramps, vitamin E, verapamil, muscle relaxants, gabapentin as search terms."4.84Are there alternatives to the use of quinine to treat nocturnal leg cramps? ( Guay, DR, 2008)
"Muscle cramps associated with PNH respond well to symptomatic treatment, particularly with carbamazepine and gabapentin."3.83Therapeutic Implications of Peripheral Nerve Hyperexcitability in Muscle Cramping: A Retrospective Review. ( Hobson-Webb, LD; Hurst, RL, 2016)
" Gabapentin therapy proved to be very satisfactory in relieving muscular cramps with a relatively low dosage (600 mg/day) and without any remarkable side effects."1.30A case of myokymia-cramp syndrome successfully treated with gabapentin. ( Cardinali, P; Parisi, L; Pierelli, F; Rossi, P; Serrao, M; Tramutoli, R, 1998)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beladi Mousavi, SS1
Zeraati, A1
Moradi, S1
Mousavi, MB1
Hurst, RL1
Hobson-Webb, LD1
Heuss, D1
Guay, DR1
Mueller, ME1
Gruenthal, M1
Olson, WL1
Olson, WH1
Serrao, M1
Cardinali, P1
Rossi, P1
Parisi, L1
Tramutoli, R1
Pierelli, F1

Reviews

1 review available for gabapentin and Muscle Cramp

ArticleYear
Are there alternatives to the use of quinine to treat nocturnal leg cramps?
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2008, Volume: 23, Issue:2

    Topics: Amines; Calcium Channel Blockers; Carisoprodol; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amino

2008

Trials

2 trials available for gabapentin and Muscle Cramp

ArticleYear
The effect of gabapentin on muscle cramps during hemodialysis: A double-blind clinical trial.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2015, Volume: 26, Issue:6

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma

2015
Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis.
    Archives of physical medicine and rehabilitation, 1997, Volume: 78, Issue:5

    Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acid

1997

Other Studies

3 other studies available for gabapentin and Muscle Cramp

ArticleYear
Therapeutic Implications of Peripheral Nerve Hyperexcitability in Muscle Cramping: A Retrospective Review.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2016, Volume: 33, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Antibodies; Carbamazepine; Cyclohexanecarboxylic Acids; Electric S

2016
[Muscle cramp--what is at the bottom of it? Only a little strained or seriously sick?].
    MMW Fortschritte der Medizin, 2006, Mar-16, Volume: 148, Issue:11

    Topics: Age Factors; Aged; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Citric Acid; Cy

2006
A case of myokymia-cramp syndrome successfully treated with gabapentin.
    Acta neurologica Scandinavica, 1998, Volume: 98, Issue:6

    Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Extremities; Fasciculation; Gabapentin; gamma-Aminobu

1998