gabapentin has been researched along with Migraine Disorders in 40 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gabapentin offers an effective, safe alternative therapy or co-therapy for the listed painful conditions and tremor; it does not affect the metabolism of other medications and is well tolerated." | 9.08 | Gabapentin for treatment of pain and tremor: a large case series. ( Merren, MD, 1998) |
| "Gabapentin, which has been approved for add-on therapy of focal seizures, is increasingly used for treatment of neuropathic pain." | 8.81 | [Gabapentin therapy for pain]. ( Block, F, 2001) |
| "There have been many proposed uses for gabapentin, including midscapular pain secondary to radiation myelopathy, RSD, neuropathic pain, postherpetic neuralgia, and migraine prophylaxis." | 8.79 | Use of gabapentin in pain management. ( Connelly, JF; Wetzel, CH, 1997) |
| "The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes." | 7.70 | Gabapentin's effects on hot flashes and hypothermia. ( Guttuso, TJ, 2000) |
| "Gabapentin offers an effective, safe alternative therapy or co-therapy for the listed painful conditions and tremor; it does not affect the metabolism of other medications and is well tolerated." | 5.08 | Gabapentin for treatment of pain and tremor: a large case series. ( Merren, MD, 1998) |
| " On the other hand, patients with divalproex exhibited significantly higher risk of nausea compared to those with placebo, topiramate, propranolol, gabapentin and amitriptyline." | 4.95 | Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. ( He, A; Li, C; Song, D; Zhang, L, 2017) |
| "Gabapentin, which has been approved for add-on therapy of focal seizures, is increasingly used for treatment of neuropathic pain." | 4.81 | [Gabapentin therapy for pain]. ( Block, F, 2001) |
| "There have been many proposed uses for gabapentin, including midscapular pain secondary to radiation myelopathy, RSD, neuropathic pain, postherpetic neuralgia, and migraine prophylaxis." | 4.79 | Use of gabapentin in pain management. ( Connelly, JF; Wetzel, CH, 1997) |
| "We examined reporting practices for trials of gabapentin funded by Pfizer and Warner-Lambert's subsidiary, Parke-Davis (hereafter referred to as Pfizer and Parke-Davis) for off-label indications (prophylaxis against migraine and treatment of bipolar disorders, neuropathic pain, and nociceptive pain), comparing internal company documents with published reports." | 3.75 | Outcome reporting in industry-sponsored trials of gabapentin for off-label use. ( Bero, L; Dickersin, K; Scherer, RW; Vedula, SS, 2009) |
| "The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes." | 3.70 | Gabapentin's effects on hot flashes and hypothermia. ( Guttuso, TJ, 2000) |
| "Both drugs were equally effective in migraine prophylaxis." | 2.78 | Comparison of efficacy and safety of topiramate with gabapentin in migraine prophylaxis: randomized open label control trial. ( Ahmed, S; Alam, R; Khan, M; Zafar, I; Zain, S, 2013) |
| "The study included 67 migraine patients, 55 women and 12 men; 52 patients completed this prospective, open-label study." | 2.74 | The efficacy of gabapentin in migraine prophylaxis: an observational open label study. ( Bosnar-Puretić, M; Demarin, V; Lovrencić-Huzjan, A; Vuković, V, 2009) |
| "Gabapentin is an effective prophylactic agent for patients with migraine." | 2.70 | Efficacy of gabapentin in migraine prophylaxis. ( Klapper, J; Magnus, L; Mathew, NT; Ramadan, N; Rapoport, A; Saper, J; Stacey, B; Tepper, S, 2001) |
| " One trial of gabapentin enacarbil (523 participants) failed to demonstrate a significant difference versus placebo or between doses for gabapentin enacarbil titrated to between 1200 mg and 3000 mg with regard to proportion of responders; there was also no evidence of a dose-response trend." | 2.49 | Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults. ( Chronicle, EP; Linde, M; McCrory, DC; Mulleners, WM, 2013) |
| "Migraine is affected by fluctuating estrogen levels so it is not surprising that the perimenopause is a time of peak rate of change of migraine prevalence in women." | 2.48 | Perimenopausal migraine in women with vasomotor symptoms. ( MacGregor, EA, 2012) |
| "Yet, migraine by itself is associated with an increased risk of suicidal ideation and behavior as well as with an increased risk of psychiatric disorders that facilitate the development of suicidal behavior." | 2.47 | Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality? ( Kanner, AM, 2011) |
| "Pediatric migraine can cause a significant impact on quality of life." | 2.45 | [Antiepileptic drugs for the prevention of pediatric migraine]. ( Cuvellier, JC, 2009) |
| "These drugs can reduce the incidence of migraine attacks in the large clinical studies." | 2.45 | [Use of antiepileptic drugs for the preventive treatment of migraine]. ( Hamada, J, 2009) |
| "A rationale for their use in migraine prophylaxis is the hypothesis that migraine and epilepsy share several common pathogenetic mechanisms." | 2.44 | Antiepileptic drugs in migraine: from clinical aspects to cellular mechanisms. ( Calabresi, P; Cupini, LM; Galletti, F; Rossi, C; Sarchielli, P, 2007) |
| "There is a general agreement now that migraine is not only a vascular phenomenon but also a genetically determined heterogenic ion-channelopathy resulting in cortical-spreading-depression-like events, the temporary impairment of antinociceptive structures of the brainstem and the activation of the trigeminal-vascular system." | 2.44 | GABAergic drugs for the treatment of migraine. ( Limmroth, V; Puppe, A, 2007) |
| "Dizziness is not a unique clinical picture, but rather is the unspecific symptom of numerous diseases." | 2.44 | [Frequently occurring forms of dizziness and their treatment]. ( Thömke, F, 2007) |
| "The mainstay of migraine treatment is pharmacotherapy." | 2.42 | The role of anticonvulsants in preventive migraine therapy. ( Corbo, J, 2003) |
| "Many migraine sufferers use daily prophylactic therapy to reduce the frequency of their headache attacks." | 1.43 | Using a graphical risk tool to examine willingness to take migraine prophylactic medications. ( Golding, AN; Houle, TT; Turner, DP, 2016) |
| "Chronic migraine is an important public health problem." | 1.36 | Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials. ( D'Amico, D, 2010) |
| "All subject's Migraine Disability Assessment Scale and VAS scores were compared." | 1.36 | Rhinologic evaluation in patients with primary headache. ( Cabalar, M; Gurer, E; Kayhan, FT; Sayin, I; Yayla, V; Yazici, ZM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (12.50) | 18.2507 |
| 2000's | 19 (47.50) | 29.6817 |
| 2010's | 13 (32.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Oliveira, ADP | 1 |
| Silva-Néto, RP | 1 |
| Lampl, C | 1 |
| MaassenVanDenBrink, A | 1 |
| Deligianni, CI | 1 |
| Gil-Gouveia, R | 1 |
| Jassal, T | 1 |
| Sanchez-Del-Rio, M | 1 |
| Reuter, U | 1 |
| Uluduz, D | 1 |
| Versijpt, J | 1 |
| Zeraatkar, D | 1 |
| Sacco, S | 1 |
| Groenke, BR | 1 |
| Daline, IH | 1 |
| Nixdorf, DR | 1 |
| Linde, M | 1 |
| Mulleners, WM | 1 |
| Chronicle, EP | 1 |
| McCrory, DC | 1 |
| Zain, S | 1 |
| Khan, M | 1 |
| Alam, R | 1 |
| Zafar, I | 1 |
| Ahmed, S | 1 |
| Fogleman, CD | 1 |
| Turner, DP | 1 |
| Golding, AN | 1 |
| Houle, TT | 1 |
| He, A | 1 |
| Song, D | 1 |
| Zhang, L | 1 |
| Li, C | 1 |
| Cuvellier, JC | 1 |
| Spears, RC | 1 |
| Andreou, AP | 1 |
| Shields, KG | 1 |
| Goadsby, PJ | 1 |
| Hamada, J | 1 |
| Vedula, SS | 2 |
| Bero, L | 1 |
| Scherer, RW | 1 |
| Dickersin, K | 2 |
| Vuković, V | 1 |
| Lovrencić-Huzjan, A | 1 |
| Bosnar-Puretić, M | 1 |
| Demarin, V | 1 |
| Robbins, MS | 1 |
| Crystal, SC | 1 |
| Grosberg, BM | 1 |
| Hutchinson, S | 1 |
| D'Amico, D | 1 |
| Yazici, ZM | 1 |
| Cabalar, M | 1 |
| Sayin, I | 1 |
| Kayhan, FT | 1 |
| Gurer, E | 1 |
| Yayla, V | 1 |
| Kanner, AM | 1 |
| MacGregor, EA | 1 |
| Goldman, PS | 1 |
| Rona, IJ | 1 |
| Greene, TM | 1 |
| Mariano Da Silva, H | 1 |
| Alcantara, MC | 1 |
| Bordini, CA | 1 |
| Speciali, JG | 1 |
| Corbo, J | 1 |
| Filatova, EG | 1 |
| Klimov, MV | 1 |
| Levin, M | 1 |
| Ward, TN | 1 |
| Larson, E | 1 |
| von Orelli, F | 1 |
| Calabresi, P | 1 |
| Galletti, F | 1 |
| Rossi, C | 1 |
| Sarchielli, P | 1 |
| Cupini, LM | 1 |
| Puppe, A | 1 |
| Limmroth, V | 1 |
| Maggioni, F | 1 |
| Mainardi, F | 1 |
| Dainese, F | 1 |
| Lisotto, C | 1 |
| Zanchin, G | 1 |
| Thömke, F | 1 |
| Wetzel, CH | 1 |
| Connelly, JF | 1 |
| Nicolodi, M | 2 |
| Del Bianco, PL | 1 |
| Sicuteri, F | 2 |
| Merren, MD | 1 |
| Guttuso, TJ | 1 |
| Leniger, T | 1 |
| Wiemann, M | 1 |
| Bingmann, D | 1 |
| Hufnagel, A | 1 |
| Bonnet, U | 1 |
| Mathew, NT | 1 |
| Rapoport, A | 1 |
| Saper, J | 1 |
| Magnus, L | 1 |
| Klapper, J | 1 |
| Ramadan, N | 1 |
| Stacey, B | 1 |
| Tepper, S | 1 |
| Block, F | 1 |
| Schoonman, GG | 1 |
| Wiendels, NJ | 1 |
| Ferrari, MD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Studying the Impact of Exercise on Hot Flashes Using Mobile Fitbit Flex, MENQOL Scale and Hot Flash Diary[NCT03236896] | 35 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| [NCT00447369] | Phase 3 | 70 participants (Anticipated) | Interventional | 2007-05-31 | Withdrawn (stopped due to Because we did not find funds to do it) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for gabapentin and Migraine Disorders
| Article | Year |
|---|---|
The comparative effectiveness of migraine preventive drugs: a systematic review and network meta-analysis.
Topics: Adult; Amitriptyline; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Gabapentin; Humans; M | 2023 |
Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults.
Topics: Adult; Amines; Anticonvulsants; Carbamates; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobuty | 2013 |
Gabapentin for the prophylaxis of episodic migraine in adults.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobut | 2014 |
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis.
Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fruct | 2017 |
[Antiepileptic drugs for the prevention of pediatric migraine].
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Tolerance; Fructose; G | 2009 |
[Use of antiepileptic drugs for the preventive treatment of migraine].
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Fructose; Gabape | 2009 |
Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality?
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Labeling; Fructose; Gabapentin; gamma-Ami | 2011 |
Perimenopausal migraine in women with vasomotor symptoms.
Topics: Amines; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Estrogens; Female; Fluoxetine; Ga | 2012 |
The role of anticonvulsants in preventive migraine therapy.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Appro | 2003 |
[Anticonvulsants in preventive therapy of migraine].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobut | 2003 |
[Nonorganic pain -- only psychogenic?].
Topics: Acetates; Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Back Pain; Chronic Dise | 2003 |
Antiepileptic drugs in migraine: from clinical aspects to cellular mechanisms.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma | 2007 |
GABAergic drugs for the treatment of migraine.
Topics: Acute Disease; Amines; Animals; Cyclohexanecarboxylic Acids; Fructose; GABA Agents; GABA Antagonists | 2007 |
[Frequently occurring forms of dizziness and their treatment].
Topics: Amines; Anticonvulsants; Betahistine; Carbamazepine; Cyclohexanecarboxylic Acids; Diagnosis, Differe | 2007 |
Use of gabapentin in pain management.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic | 1997 |
[Gabapentin therapy for pain].
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neurop | 2001 |
4 trials available for gabapentin and Migraine Disorders
| Article | Year |
|---|---|
Comparison of efficacy and safety of topiramate with gabapentin in migraine prophylaxis: randomized open label control trial.
Topics: Adult; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin | 2013 |
The efficacy of gabapentin in migraine prophylaxis: an observational open label study.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; H | 2009 |
Gabapentin for treatment of pain and tremor: a large case series.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Anticonvulsants; Arachnoiditis; Cerebellar Neoplasms; Cyc | 1998 |
Efficacy of gabapentin in migraine prophylaxis.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Met | 2001 |
20 other studies available for gabapentin and Migraine Disorders
| Article | Year |
|---|---|
Circadian rhythmicity on red ear syndrome in a patient with migraine: A case report.
Topics: Adult; Circadian Rhythm; Ear; Erythema; Female; Gabapentin; Humans; Migraine Disorders; Pain; Parest | 2021 |
SUNCT/SUNA: Case series presenting in an orofacial pain clinic.
Topics: Adult; Autonomic Nervous System Diseases; Facial Pain; Female; Gabapentin; Headache Disorders; Human | 2021 |
Using a graphical risk tool to examine willingness to take migraine prophylactic medications.
Topics: Amines; Analgesics; Antidepressive Agents; Antihypertensive Agents; Cross-Sectional Studies; Cyclohe | 2016 |
Is gabapentin an effective treatment choice for hemicrania continua?
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Pathways; Cyclohexanec | 2009 |
GABA and valproate modulate trigeminovascular nociceptive transmission in the thalamus.
Topics: Amines; Animals; Anticonvulsants; Cerebral Arteries; Cyclohexanecarboxylic Acids; Disease Models, An | 2010 |
Outcome reporting in industry-sponsored trials of gabapentin for off-label use.
Topics: Amines; Bipolar Disorder; Clinical Protocols; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobu | 2009 |
Teaching case: menopausal migraine.
Topics: Amines; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Fructose; Gabapentin; gamma-Aminobutyric | 2010 |
Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials.
Topics: Amines; Analgesics; Chronic Disease; Clonidine; Cyclohexanecarboxylic Acids; Diagnosis, Differential | 2010 |
Rhinologic evaluation in patients with primary headache.
Topics: Adolescent; Adult; Amines; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Endoscopy; | 2010 |
Off-label prescribing explained. Why your doctor may recommend meds that aren't FDA-approved for your condition.
Topics: Amines; Bipolar Disorder; Clinical Protocols; Cyclohexanecarboxylic Acids; Drug Approval; Drug Label | 2011 |
Implementation of a publication strategy in the context of reporting biases. A case study based on new documents from Neurontin litigation.
Topics: Access to Information; Amines; Analgesics; Antimanic Agents; Authorship; Bipolar Disorder; Clinical | 2012 |
Strictly unilateral headache reminiscent of hemicrania continua resistant to indomethacin but responsive to gabapentin.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Blepharoptosis; Cyclohexanecarboxy | 2002 |
Migraine-tic syndrome: a case report of a new headache type.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; g | 2004 |
Migraine secondary to superior oblique myokymia.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; | 2007 |
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagon | 1997 |
Negative modultors of excitatory amino acids in episodic and chronic migraine: preventing and reverting chronic migraine. Special lecture 7th INWIN Congress.
Topics: Acetates; Adult; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; E | 1998 |
Gabapentin. CI 945, GOE 3450, Neurontin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Area Under Curve; Biological Availability; Child; Child, P | 1999 |
Gabapentin's effects on hot flashes and hypothermia.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gab | 2000 |
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecar | 2000 |
Gabapentin in migraine prophylaxis: is it effective and well tolerated?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Huma | 2002 |