Page last updated: 2024-10-27

gabapentin and Lesch-Nyhan Syndrome

gabapentin has been researched along with Lesch-Nyhan Syndrome in 1 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Lesch-Nyhan Syndrome: An inherited disorder transmitted as a sex-linked trait and caused by a deficiency of an enzyme of purine metabolism; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE. Affected individuals are normal in the first year of life and then develop psychomotor retardation, extrapyramidal movement disorders, progressive spasticity, and seizures. Self-destructive behaviors such as biting of fingers and lips are seen frequently. Intellectual impairment may also occur but is typically not severe. Elevation of uric acid in the serum leads to the development of renal calculi and gouty arthritis. (Menkes, Textbook of Child Neurology, 5th ed, pp127)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McManaman, J1
Tam, DA1

Other Studies

1 other study available for gabapentin and Lesch-Nyhan Syndrome

ArticleYear
Gabapentin for self-injurious behavior in Lesch-Nyhan syndrome.
    Pediatric neurology, 1999, Volume: 20, Issue:5

    Topics: Acetates; Amines; Child, Preschool; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Am

1999