Page last updated: 2024-10-27

gabapentin and Joint Pain

gabapentin has been researched along with Joint Pain in 13 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" Recently, preoperative pain facilitation has been associated with chronic pain after TKA, and gabapentin has been shown to decrease pain facilitation."5.27The influence of pre- and perioperative administration of gabapentin on pain 3-4 years after total knee arthroplasty. ( Arendt-Nielsen, L; Hansen, LT; Husted, H; Kehlet, H; Kjær Petersen, K; Laursen, MB; Lunn, TH; Simonsen, O, 2018)
"Treatment with gabapentin led to recovered behaviour and DH neuronal activity pattern in CFA-treated animals."1.62Dorsal horn disinhibition and movement-induced behaviour in a rat model of inflammatory arthritis. ( Locke, S; Ribeiro-da-Silva, A; Yousefpour, N, 2021)
"Myalgia and arthralgia immune-related adverse events (irAEs) in patients treated with checkpoint inhibitors (CPIs) present a clinical challenge."1.51Myalgia and Arthralgia Immune-related Adverse Events (irAEs) in Patients With Genitourinary Malignancies Treated With Immune Checkpoint Inhibitors. ( Allman, KD; Calabrese, C; Calabrese, LH; Garcia, JA; Grivas, P; Kirchner, E; Kontzias, A; Martin, A; Ornstein, MC; Profusek, P; Rini, BI; Wood, LS, 2019)
"Although joint pain is common, its mechanisms remain undefined, with little known about the spinal neuronal responses that contribute to this type of pain."1.39Gabapentin alleviates facet-mediated pain in the rat through reduced neuronal hyperexcitability and astrocytic activation in the spinal cord. ( Crosby, ND; Dong, L; Winkelstein, BA, 2013)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's7 (53.85)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Locke, S1
Yousefpour, N1
Ribeiro-da-Silva, A1
Kjær Petersen, K1
Lunn, TH1
Husted, H1
Hansen, LT1
Simonsen, O1
Laursen, MB1
Kehlet, H1
Arendt-Nielsen, L1
Aman, Y1
Pitcher, T1
Ballard, C1
Malcangio, M1
Ter Heegde, F1
Luiz, AP1
Santana-Varela, S1
Chessell, IP1
Welsh, F1
Wood, JN1
Chenu, C1
Ornstein, MC1
Calabrese, C1
Wood, LS1
Kirchner, E1
Profusek, P1
Allman, KD1
Martin, A1
Kontzias, A1
Grivas, P1
Garcia, JA1
Calabrese, LH1
Rini, BI1
Dong, L2
Crosby, ND2
Winkelstein, BA2
Zaucke, F1
Kras, JV1
Luo, ZD1
Bas, DB1
Su, J1
Sandor, K1
Agalave, NM1
Lundberg, J1
Codeluppi, S1
Baharpoor, A1
Nandakumar, KS1
Holmdahl, R1
Svensson, CI1
Arvio, M1
Merikanto, J1
Nguyen, VH1
Lawrence, HJ1
Almahrezi, A1
Fitzcharles, MA1
Bove, SE1
Laemont, KD1
Brooker, RM1
Osborn, MN1
Sanchez, BM1
Guzman, RE1
Hook, KE1
Juneau, PL1
Connor, JR1
Kilgore, KS1
Rovetta, G1
Baratto, L1
Farinelli, G1
Monteforte, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia[NCT02024568]Phase 238 participants (Anticipated)Interventional2013-12-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for gabapentin and Joint Pain

ArticleYear
The influence of pre- and perioperative administration of gabapentin on pain 3-4 years after total knee arthroplasty.
    Scandinavian journal of pain, 2018, 04-25, Volume: 18, Issue:2

    Topics: Aged; Analgesics; Arthralgia; Arthroplasty, Replacement, Knee; Chronic Pain; Female; Follow-Up Studi

2018

Other Studies

12 other studies available for gabapentin and Joint Pain

ArticleYear
Dorsal horn disinhibition and movement-induced behaviour in a rat model of inflammatory arthritis.
    Rheumatology (Oxford, England), 2021, 02-01, Volume: 60, Issue:2

    Topics: Adjuvants, Immunologic; Analgesics; Animals; Arthralgia; Arthritis; Behavior, Animal; Disease Models

2021
Impaired chronic pain-like behaviour and altered opioidergic system in the TASTPM mouse model of Alzheimer's disease.
    European journal of pain (London, England), 2019, Volume: 23, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analgesics; Analgesics, Opioid; Animals; Arthralg

2019
Noninvasive Mechanical Joint Loading as an Alternative Model for Osteoarthritic Pain.
    Arthritis & rheumatology (Hoboken, N.J.), 2019, Volume: 71, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Behavior, Animal; Cartilag

2019
Myalgia and Arthralgia Immune-related Adverse Events (irAEs) in Patients With Genitourinary Malignancies Treated With Immune Checkpoint Inhibitors.
    Clinical genitourinary cancer, 2019, Volume: 17, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Arthralgia; B7-H1 Antigen; Drug Therapy; Etanercept;

2019
Gabapentin alleviates facet-mediated pain in the rat through reduced neuronal hyperexcitability and astrocytic activation in the spinal cord.
    The journal of pain, 2013, Volume: 14, Issue:12

    Topics: Amines; Analgesics; Animals; Arthralgia; Astrocytes; Cyclohexanecarboxylic Acids; Gabapentin; gamma-

2013
Thrombospondin-4 and excitatory synaptogenesis promote spinal sensitization after painful mechanical joint injury.
    Experimental neurology, 2015, Volume: 264

    Topics: Action Potentials; Amines; Analgesics; Animals; Arthralgia; Cyclohexanecarboxylic Acids; Excitatory

2015
Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:12

    Topics: Amines; Analgesics; Animals; Arthralgia; Arthritis, Experimental; Buprenorphine; Cyclohexanecarboxyl

2012
[A relief from neural pain--gabapentin helped against hip ache in a girl with cerebral palsy].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:14

    Topics: Acetates; Adolescent; Amines; Analgesics; Arthralgia; Cerebral Palsy; Cyclohexanecarboxylic Acids; F

2001
Use of gabapentin in the prevention of taxane-induced arthralgias and myalgias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9

    Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Arthralgia; Cyclohexanecarboxylic A

2004
Dose-dependent severe arthralgia induced by gabapentin.
    The Journal of rheumatology, 2004, Volume: 31, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acids; Female; Gabapenti

2004
Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia.
    Osteoarthritis and cartilage, 2006, Volume: 14, Issue:10

    Topics: Amines; Analgesics; Animals; Arthralgia; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; D

2006
Three-month follow-up of shoulder-hand syndrome induced by phenobarbital and treated with gabapentin.
    International journal of tissue reactions, 2001, Volume: 23, Issue:1

    Topics: Acetaminophen; Acetates; Amines; Analgesics; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acid

2001