Page last updated: 2024-10-27

gabapentin and Itching

gabapentin has been researched along with Itching in 74 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin and intravenous patient-controlled analgesia (PCA) can reduce postoperative pain scores, postoperative opioid use, and time to completing physical therapy compared to PCA alone after posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS)."9.41Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis. ( Caird, MS; Hong, RA; Leis, A; Li, Y; Robbins, C; Swallow, J, 2021)
"Gabapentin and doxepin are well-known treatments of uremic pruritus in hemodialysis patients but no head-to-head studies were conducted to date."9.34Comparison of gabapentin and doxepin in the management of uremic pruritus: A randomized crossover clinical trial. ( Ammoury, A; Bachour, J; Haber, R; Habr, L; Joubran, N; Khoury, F; Maacaron, T; Salloum, A, 2020)
"To compare the effect of gabapentin (GBP) and hydroxyzine (HYDZ) in treating pruritus in patients on dialysis."9.34Comparison of gabapentin and hydroxyzine in the treatment of pruritus in patients on dialysis. ( Ghorghani, M; Hoseininia, S; Mohammadi Kebar, S; Sharghi, A, 2020)
" Treatment with 6% topical gabapentin resulted in significantly decreased mean pruritus scores at 1 week (mean score 2."9.34A randomized controlled study of 6% gabapentin topical formulation for chronic kidney disease-associated pruritus. ( Aquino, TMO; Luchangco, KAC; Sanchez, EV; Verallo-Rowell, VM, 2020)
" dexchlorpheniramine in reducing uremic pruritus."9.27Gabapentin versus dexchlorpheniramine as treatment for uremic pruritus: a randomised controlled trial. ( Abbade, LP; Gobo-Oliveira, M; Miot, HA; Ogata, MS; Pigari, VG; Ponce, D, 2018)
"Gabapentin relieved itching in 47 patients (66%)."9.16Uraemic pruritus: relief of itching by gabapentin and pregabalin. ( Baharani, J; Dasgupta, I; Rayner, H; Smith, S; Suresh, V, 2012)
"To compare the efficacy and side effects of gabapentin and desloratadine in patients with dialysis pruritus."9.16Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin. ( Barrón, B; Lauxmann, JE; Marquez, D; Martinatto, C; Novoa, PA; Orías, M; Peixoto, AJ; Ramonda, C; Romero, CA; Vukelic, VL, 2012)
"Gabapentin is an effective agent in treating uremic pruritus."9.14Gabapentin and uremic pruritus in hemodialysis patients. ( Eskandari, D; Ganji, MR; Khashayar, P; Meysamie, AP; Razeghi, E; Togha, M, 2009)
"The incidence of pruritus was significantly more frequent in the placebo group compared with the gabapentin group (77."9.13Preoperative gabapentin prevents intrathecal morphine-induced pruritus after orthopedic surgery. ( Chang, FL; Ho, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008)
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception."9.12Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006)
"Our study shows that gabapentin is safe and effective for treating uraemic pruritus in haemodialysis patients."9.11Gabapentin therapy for pruritus in haemodialysis patients: a randomized, placebo-controlled, double-blind trial. ( Celiker, H; Gunal, AI; Gunal, SY; Kirciman, E; Ozalp, G; Yoldas, TK, 2004)
"Gabapentin has an antipruritus effect, which its efficacy in reducing pruritus induced by intrathecal morphine has not been well documented."8.88Single dose of gabapentin for prophylaxis intrathecal morphine-induced pruritus in orthopedic surgery: a randomized controlled trial. ( Chiravanich, W; Kovitwanawong, N; Oofuvong, M, 2012)
"To evaluate the efficacy and safety of gabapentin and oral antidepressants in patients with chronic pruritus in daily clinical practice."8.31Gabapentin and oral antidepressants for chronic pruritus: a prospective cohort study evaluating efficacy and side effects in daily dermatological practice. ( Kamsteeg, M; Kouwenhoven, TA; van de Kerkhof, PCM, 2023)
"A retrospective review of charts and pharmacy records of gabapentin and pregabalin dispensed to control pruritus and/or pain was conducted for burn survivors up to 20 years of age."7.88Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review. ( Amin, A; Kaul, I; Meyer, WJ; Rosenberg, L; Rosenberg, M, 2018)
"To determine the safety and effectiveness of gabapentin for pruritus or RLS in conservatively managed patients (n = 34) with CKD and ESKD."7.81Efficacy and safety of gabapentin for uremic pruritus and restless legs syndrome in conservatively managed patients with chronic kidney disease. ( Brennan, F; Brown, MA; Cheikh Hassan, HI; Collett, G; Josland, EA, 2015)
"Compared with that before treatment, the itching degree of patients with light, moderate, and severe itching in placebo group was not relieved after treatment; the itching degree of patients with moderate or severe itching in cetirizine group was alleviated after treatment, but not in patients with light itching; itching degree of all patients in gabapentin group was significantly relieved after treatment."7.81[Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn]. ( Bing, Z; Qiang, W; Wei, L; Zheng, L, 2015)
"Itching was induced via neonatal capsaicin treatment in Sprague-Dawley rats (itching rats), and scratching behavior of the control, itching, and gabapentin (GBP)-treated itching rats was compared."7.81Investigation of the pruritus-induced functional activity in the rat brain using manganese-enhanced MRI. ( Jeong, KY; Kang, JH, 2015)
"To evaluate the efficacy of gabapentin for the treatment of uremic pruritus (UP)."7.74Role of gabapentin in the treatment of uremic pruritus. ( Gommer, J; Scates, AC; Vila, T, 2008)
"We describe the use of gabapentin for the treatment of itching in wound healing in 35 children."7.72Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study. ( Mendham, JE, 2004)
"Pruritus is a symptom that adversely affects the quality of life of patients with epidermolysis bullosa (EB)."7.11Topical gabapentin 10% in the treatment of epidermolysis bullosa pruritus: A pilot, double-blind, split-site, randomized controlled trial. ( Ahramiyanpour, N; Hosseini, SA; Parvizi, MM; Saki, N; Shafie'ei, M; Vahedi, S, 2022)
"Gabapentin is a promising and a well-tolerated treatment option for patients with UP."6.82Gabapentin: A promising therapy for uremic pruritus in hemodialysis patients: A randomized-controlled trial and review of literature. ( Abdelkhalik, Z; Alkot, R; Eldesouky, F; Farag, F; Nofal, A; Nofal, E, 2016)
"Pruritus is common in dialysis patients."6.77Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study. ( Atalay, H; Biyik, Z; Covic, A; Gaipov, A; Goldsmith, D; Guney, F; Kanbay, M; Solak, Y; Turk, S, 2012)
"Gabapentin is an antiepileptic drug which has been successfully used to manage neuropathic pain, and is reporting to be successful in management of all forms of itch."6.76A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus. ( Ahuja, RB; Gupta, G; Gupta, R; Shrivastava, P, 2011)
"Gabapentin is an effective drug in the management of neuropathic pain."6.73Gabapentin: a promising drug for the treatment of uremic pruritus. ( Harandi, AA; Khanbabapour, S; Mohseni, M; Naini, AE; Seirafiyan, S; Shahidi, S, 2007)
"Uremic pruritus is one of the most prevalent and bothersome dermatologic symptoms in patients with end-stage renal disease."6.66Gabapentin for uremic pruritus: a systematic review of randomized controlled trials. ( Castillo, RL; Dofitas, BL; Eusebio-Alpapara, KMV, 2020)
"Chronic pruritus is a distressing symptom that is often refractory to treatment."6.53Gabapentin and pregabalin for the treatment of chronic pruritus. ( Kwatra, SG; Matsuda, KM; Schonfeld, AR; Sharma, D, 2016)
"Gabapentin and intravenous patient-controlled analgesia (PCA) can reduce postoperative pain scores, postoperative opioid use, and time to completing physical therapy compared to PCA alone after posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS)."5.41Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis. ( Caird, MS; Hong, RA; Leis, A; Li, Y; Robbins, C; Swallow, J, 2021)
"Brachioradial pruritus is a characteristic clinical condition with a deep intense itching, tingling or burning sensation localized to the dorsolateral part of the upper extremities."5.38[Brachioradial pruritus effectively treated with gabapentin]. ( Bygum, A; Uldall Pallesen, KA, 2012)
" Treatment with 6% topical gabapentin resulted in significantly decreased mean pruritus scores at 1 week (mean score 2."5.34A randomized controlled study of 6% gabapentin topical formulation for chronic kidney disease-associated pruritus. ( Aquino, TMO; Luchangco, KAC; Sanchez, EV; Verallo-Rowell, VM, 2020)
"To compare the effect of gabapentin (GBP) and hydroxyzine (HYDZ) in treating pruritus in patients on dialysis."5.34Comparison of gabapentin and hydroxyzine in the treatment of pruritus in patients on dialysis. ( Ghorghani, M; Hoseininia, S; Mohammadi Kebar, S; Sharghi, A, 2020)
"Gabapentin and doxepin are well-known treatments of uremic pruritus in hemodialysis patients but no head-to-head studies were conducted to date."5.34Comparison of gabapentin and doxepin in the management of uremic pruritus: A randomized crossover clinical trial. ( Ammoury, A; Bachour, J; Haber, R; Habr, L; Joubran, N; Khoury, F; Maacaron, T; Salloum, A, 2020)
" dexchlorpheniramine in reducing uremic pruritus."5.27Gabapentin versus dexchlorpheniramine as treatment for uremic pruritus: a randomised controlled trial. ( Abbade, LP; Gobo-Oliveira, M; Miot, HA; Ogata, MS; Pigari, VG; Ponce, D, 2018)
"To compare the efficacy and side effects of gabapentin and desloratadine in patients with dialysis pruritus."5.16Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin. ( Barrón, B; Lauxmann, JE; Marquez, D; Martinatto, C; Novoa, PA; Orías, M; Peixoto, AJ; Ramonda, C; Romero, CA; Vukelic, VL, 2012)
"Gabapentin relieved itching in 47 patients (66%)."5.16Uraemic pruritus: relief of itching by gabapentin and pregabalin. ( Baharani, J; Dasgupta, I; Rayner, H; Smith, S; Suresh, V, 2012)
"Gabapentin is an effective agent in treating uremic pruritus."5.14Gabapentin and uremic pruritus in hemodialysis patients. ( Eskandari, D; Ganji, MR; Khashayar, P; Meysamie, AP; Razeghi, E; Togha, M, 2009)
"The incidence of pruritus was significantly more frequent in the placebo group compared with the gabapentin group (77."5.13Preoperative gabapentin prevents intrathecal morphine-induced pruritus after orthopedic surgery. ( Chang, FL; Ho, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008)
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception."5.12Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006)
"Our study shows that gabapentin is safe and effective for treating uraemic pruritus in haemodialysis patients."5.11Gabapentin therapy for pruritus in haemodialysis patients: a randomized, placebo-controlled, double-blind trial. ( Celiker, H; Gunal, AI; Gunal, SY; Kirciman, E; Ozalp, G; Yoldas, TK, 2004)
" In the meantime, gabapentin appears to be the most evidence-based widely available uremic pruritus treatment, as long as care is taken with dosing and monitoring of side-effects."5.05Recent advances in the treatment of uremic pruritus. ( Collister, D; Rigatto, C; Trachtenberg, AJ, 2020)
"Despite the acknowledged importance of uremic pruritus to patients, with the exception of gabapentin, the current evidence for treatments is weak."4.95Treatment of Uremic Pruritus: A Systematic Review. ( Askin, N; Bohm, C; Komenda, P; Lerner, B; Rigatto, C; Shaw, J; Simonsen, E; Tangri, N, 2017)
" The complications of vomiting, nausea, dizziness and pruritus were also compiled to assess the safety of gabapentin and pregabalin."4.93The efficacy of preoperative administration of gabapentin/pregabalin in improving pain after total hip arthroplasty: a meta-analysis. ( Ding, W; Mao, Y; Wu, L, 2016)
"Gabapentin has an antipruritus effect, which its efficacy in reducing pruritus induced by intrathecal morphine has not been well documented."4.88Single dose of gabapentin for prophylaxis intrathecal morphine-induced pruritus in orthopedic surgery: a randomized controlled trial. ( Chiravanich, W; Kovitwanawong, N; Oofuvong, M, 2012)
"To evaluate the efficacy and safety of gabapentin and oral antidepressants in patients with chronic pruritus in daily clinical practice."4.31Gabapentin and oral antidepressants for chronic pruritus: a prospective cohort study evaluating efficacy and side effects in daily dermatological practice. ( Kamsteeg, M; Kouwenhoven, TA; van de Kerkhof, PCM, 2023)
"We studied 23 patients with severe pruritus scoring at least 5 on the visual analogue scale (VAS) and refractory to antihistamine and gabapentin administration."3.88Effect of cold pack therapy for management of burn scar pruritus: A pilot study. ( Cho, YS; Joo, SY; Kim, JB; Seo, CH, 2018)
"A retrospective review of charts and pharmacy records of gabapentin and pregabalin dispensed to control pruritus and/or pain was conducted for burn survivors up to 20 years of age."3.88Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review. ( Amin, A; Kaul, I; Meyer, WJ; Rosenberg, L; Rosenberg, M, 2018)
"Itching was induced via neonatal capsaicin treatment in Sprague-Dawley rats (itching rats), and scratching behavior of the control, itching, and gabapentin (GBP)-treated itching rats was compared."3.81Investigation of the pruritus-induced functional activity in the rat brain using manganese-enhanced MRI. ( Jeong, KY; Kang, JH, 2015)
"Compared with that before treatment, the itching degree of patients with light, moderate, and severe itching in placebo group was not relieved after treatment; the itching degree of patients with moderate or severe itching in cetirizine group was alleviated after treatment, but not in patients with light itching; itching degree of all patients in gabapentin group was significantly relieved after treatment."3.81[Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn]. ( Bing, Z; Qiang, W; Wei, L; Zheng, L, 2015)
"To determine the safety and effectiveness of gabapentin for pruritus or RLS in conservatively managed patients (n = 34) with CKD and ESKD."3.81Efficacy and safety of gabapentin for uremic pruritus and restless legs syndrome in conservatively managed patients with chronic kidney disease. ( Brennan, F; Brown, MA; Cheikh Hassan, HI; Collett, G; Josland, EA, 2015)
" Gabapentin has been successfully used to treat cutaneous pain and pruritus in a variety of conditions."3.77A case of post-herpetic itch resolved with gabapentin. ( Jagdeo, J; Kroshinsky, D, 2011)
"To evaluate the efficacy of gabapentin for the treatment of uremic pruritus (UP)."3.74Role of gabapentin in the treatment of uremic pruritus. ( Gommer, J; Scates, AC; Vila, T, 2008)
"We describe the use of gabapentin for the treatment of itching in wound healing in 35 children."3.72Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study. ( Mendham, JE, 2004)
"Pruritus is a symptom that adversely affects the quality of life of patients with epidermolysis bullosa (EB)."3.11Topical gabapentin 10% in the treatment of epidermolysis bullosa pruritus: A pilot, double-blind, split-site, randomized controlled trial. ( Ahramiyanpour, N; Hosseini, SA; Parvizi, MM; Saki, N; Shafie'ei, M; Vahedi, S, 2022)
"Brachioradial pruritis is a rare dysesthesia syndrome that is known to negatively impact quality of life."2.82Treatment modalities in brachioradial pruritis: a systematic review. ( Amerson, E; Zakaria, A, 2022)
"Gabapentin is a promising and a well-tolerated treatment option for patients with UP."2.82Gabapentin: A promising therapy for uremic pruritus in hemodialysis patients: A randomized-controlled trial and review of literature. ( Abdelkhalik, Z; Alkot, R; Eldesouky, F; Farag, F; Nofal, A; Nofal, E, 2016)
"Pruritus is common in dialysis patients."2.77Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study. ( Atalay, H; Biyik, Z; Covic, A; Gaipov, A; Goldsmith, D; Guney, F; Kanbay, M; Solak, Y; Turk, S, 2012)
"Gabapentin is an antiepileptic drug which has been successfully used to manage neuropathic pain, and is reporting to be successful in management of all forms of itch."2.76A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus. ( Ahuja, RB; Gupta, G; Gupta, R; Shrivastava, P, 2011)
"Gabapentin is an effective drug in the management of neuropathic pain."2.73Gabapentin: a promising drug for the treatment of uremic pruritus. ( Harandi, AA; Khanbabapour, S; Mohseni, M; Naini, AE; Seirafiyan, S; Shahidi, S, 2007)
"Post-burn pruritus is the pruritus that occurs after burn during the rehabilitation and healing process of burn wounds."2.66Post-Burn Pruritus. ( Chung, BY; Jung, MJ; Kang, SY; Kim, HB; Kim, HO; Kwak, IS; Park, CW, 2020)
"Uremic pruritus is one of the most prevalent and bothersome dermatologic symptoms in patients with end-stage renal disease."2.66Gabapentin for uremic pruritus: a systematic review of randomized controlled trials. ( Castillo, RL; Dofitas, BL; Eusebio-Alpapara, KMV, 2020)
"Dermatologists play a key role in the treatment of CTCL-pruritus by guiding the patient in the importance of preserving the integrity of the skin barrier."2.58Pruritus in Cutaneous T-Cell Lymphoma and Its Management. ( Guitart, J; Martinez-Escala, ME; Serrano, L; Zhou, XA, 2018)
"Chronic pruritus is a distressing symptom that is often refractory to treatment."2.53Gabapentin and pregabalin for the treatment of chronic pruritus. ( Kwatra, SG; Matsuda, KM; Schonfeld, AR; Sharma, D, 2016)
"The risk ratios (95% CI) for postoperative nausea, vomiting, pruritus and sedation with gabapentin were: 0."2.52A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain. ( Doleman, B; Faleiro, RJ; Heinink, TP; Lund, JN; Read, DJ; Williams, JP, 2015)
"Post burn pruritus is a well recognised symptom in almost all burn patients."2.48Post burn pruritus--a review of current treatment options. ( Gupta, AK; Lamba, S; Paul, MK; Prabha, R; Rao, AL; Zachariah, JR, 2012)
" As only a minority of respondents felt comfortable prescribing these drugs, more education on effective and safe dosing is needed."1.51Use of Systemic Treatment in Patients with Chronic Pruritus: A Survey of Dermatologists in the Netherlands. ( Kamsteeg, M; Kouwenhoven, TA; van de Kerkhof, PCM, 2019)
"Gabapentin was used by 45% as first-, second-, or third-line treatment."1.46International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis. ( Bieber, BA; Ecder, T; Graham-Brown, M; Hasegawa, T; Kleophas, W; Larkina, M; Pisoni, RL; Rayner, HC; Robinson, BM; Tentori, F; van der Veer, SN; Wang, M, 2017)
"Treatment with gabapentin led to a prompt reduction of the symptoms."1.39Episodic itch in a case of spinal glioma. ( Dihné, M; Lerche, H; Wolking, S, 2013)
"Brachioradial pruritus is a characteristic clinical condition with a deep intense itching, tingling or burning sensation localized to the dorsolateral part of the upper extremities."1.38[Brachioradial pruritus effectively treated with gabapentin]. ( Bygum, A; Uldall Pallesen, KA, 2012)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.35)18.2507
2000's17 (22.97)29.6817
2010's42 (56.76)24.3611
2020's14 (18.92)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Li, Y1
Swallow, J1
Robbins, C1
Caird, MS1
Leis, A1
Hong, RA1
Gutierrez, RA1
Berger, TG1
Shah, V1
Agnihothri, R1
Demir-Deviren, S1
Fassett, MS1
Saki, N1
Vahedi, S1
Parvizi, MM1
Shafie'ei, M1
Hosseini, SA1
Ahramiyanpour, N1
Zakaria, A1
Amerson, E1
Kouwenhoven, TA2
van de Kerkhof, PCM2
Kamsteeg, M2
Rossi, GM1
Corradini, M1
Blanco, V1
Mattei, S1
Fiaccadori, E1
Vaglio, A4
Manenti, L4
Uysal Tan, F1
Koc, RS1
Erkek Ozturk Durmaz, E1
Tuncez Akyurek, F1
Eusebio-Alpapara, KMV1
Castillo, RL1
Dofitas, BL1
Krajewski, P1
Szepietowski, JC2
Mohammadi Kebar, S1
Sharghi, A1
Ghorghani, M1
Hoseininia, S1
Aquino, TMO1
Luchangco, KAC1
Sanchez, EV1
Verallo-Rowell, VM1
Chung, BY1
Kim, HB1
Jung, MJ1
Kang, SY1
Kwak, IS1
Park, CW1
Kim, HO1
Trachtenberg, AJ1
Collister, D1
Rigatto, C2
Haber, R1
Bachour, J1
Salloum, A1
Maacaron, T1
Khoury, F1
Habr, L1
Ammoury, A1
Joubran, N1
Russell, M1
Zare, M1
Lee, HG1
Grossman, SK1
Valdes-Rodriguez, R1
Berenato, F1
Korbutov, J1
Chan, YH1
Lavery, MJ1
Yosipovitch, G2
Simonsen, E1
Komenda, P1
Lerner, B1
Askin, N1
Bohm, C1
Shaw, J1
Tangri, N1
Kaul, I1
Amin, A1
Rosenberg, M1
Rosenberg, L1
Meyer, WJ1
Rayner, HC1
Larkina, M1
Wang, M1
Graham-Brown, M1
van der Veer, SN1
Ecder, T1
Hasegawa, T1
Kleophas, W1
Bieber, BA1
Tentori, F1
Robinson, BM1
Pisoni, RL1
Joo, SY1
Kim, JB1
Cho, YS2
Seo, CH1
Akiyama, T1
Andoh, T1
Ohtsuka, E1
Nojima, H1
Ouchi, H1
Takahata, H1
Kuraishi, Y1
Pereira, MP1
Basta, S1
Moore, J1
Ständer, S2
Serrano, L1
Martinez-Escala, ME1
Zhou, XA1
Guitart, J1
Reszke, R1
Gobo-Oliveira, M1
Pigari, VG1
Ogata, MS1
Miot, HA1
Ponce, D1
Abbade, LP1
Rayner, H1
Baharani, J1
Smith, S1
Suresh, V1
Dasgupta, I1
Bernhard, JD3
Wolking, S1
Lerche, H1
Dihné, M1
Mettang, T2
Kremer, AE1
Yong, AS1
Lee, KY1
Cheikh Hassan, HI1
Brennan, F1
Collett, G1
Josland, EA1
Brown, MA1
Jeong, KY1
Kang, JH1
Doleman, B1
Heinink, TP1
Read, DJ1
Faleiro, RJ1
Lund, JN1
Williams, JP1
Zheng, L1
Bing, Z1
Wei, L1
Qiang, W1
Nofal, E1
Farag, F1
Nofal, A1
Eldesouky, F1
Alkot, R1
Abdelkhalik, Z1
Zhai, L1
Song, Z1
Liu, K1
Matsuda, KM1
Sharma, D1
Schonfeld, AR1
Kwatra, SG1
Ward, RE1
Veerula, VL1
Ezra, N1
Travers, JB1
Mousdicas, N1
Mao, Y1
Wu, L1
Ding, W1
Pongcharoen, P1
Fleischer, AB1
Şavk, E1
Hoeijmakers, JG1
Faber, CG1
Miedema, CJ1
Merkies, IS1
Vles, JS1
Razeghi, E1
Eskandari, D1
Ganji, MR1
Meysamie, AP1
Togha, M1
Khashayar, P1
Clarke, H1
Pereira, S1
Kennedy, D1
Andrion, J1
Mitsakakis, N1
Gollish, J1
Katz, J1
Kay, J1
Yilmaz, S1
Ceyhan, AM1
Baysal Akkaya, V1
Bang, SR1
Yu, SK1
Kim, TH1
Nakamizo, S1
Miyachi, Y1
Kabashima, K1
Ahuja, RB1
Gupta, R1
Gupta, G1
Shrivastava, P1
Jagdeo, J1
Kroshinsky, D1
Zachariah, JR1
Rao, AL1
Prabha, R1
Gupta, AK1
Paul, MK1
Lamba, S1
Chiravanich, W1
Oofuvong, M1
Kovitwanawong, N1
Anand, S1
Uldall Pallesen, KA1
Bygum, A1
Marquez, D1
Ramonda, C1
Lauxmann, JE1
Romero, CA1
Vukelic, VL1
Martinatto, C1
Barrón, B1
Novoa, PA1
Peixoto, AJ1
Orías, M1
Solak, Y1
Biyik, Z1
Atalay, H1
Gaipov, A1
Guney, F1
Turk, S1
Covic, A1
Goldsmith, D1
Kanbay, M1
Winhoven, SM1
Coulson, IH1
Bottomley, WW1
Mendham, JE1
Gunal, AI1
Ozalp, G1
Yoldas, TK1
Gunal, SY1
Kirciman, E1
Celiker, H1
Schürmeyer-Horst, F1
Fischbach, R1
Nabavi, D1
Metze, D1
Yesudian, PD1
Wilson, NJ1
Demierre, MF1
Taverna, J1
Bergasa, NV1
McGee, M1
Ginsburg, IH1
Engler, D1
Kosmadakis, GC1
Zerefos, N1
Naini, AE1
Harandi, AA1
Khanbabapour, S1
Shahidi, S1
Seirafiyan, S1
Mohseni, M1
Loosemore, MP1
Bordeaux, JS1
Borgatti, PP1
Vila, T1
Gommer, J1
Scates, AC1
Sheen, MJ1
Ho, ST1
Lee, CH1
Tsung, YC1
Chang, FL1
Bueller, HA1
Dubroff, LM1

Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns[NCT06104540]24 participants (Anticipated)Interventional2023-11-01Not yet recruiting
The Treatment Effect of Chinese Medicine Formula on Uremic Pruritus[NCT04650750]Early Phase 160 participants (Anticipated)Interventional2020-12-01Not yet recruiting
Prospective Randomized Study Evaluating the Efficacy of the Spherical Absorptive Carbon AST-120 in Hemodialysis Patients With Uremic Pruritus..[NCT04639674]Phase 4100 participants (Actual)Interventional2020-07-02Completed
A pRospective, Case-controlled Evaluation of oLIceridine for Moderate or sEVEre Pain in Patients With Acute Burn Injuries. (RELIEVE)[NCT05465226]Phase 431 participants (Actual)Interventional2023-04-01Completed
Effectiveness of Sertraline in Alleviating Uremic Pruritis in Hemodialysis Patients[NCT05341843]Phase 260 participants (Actual)Interventional2022-05-01Completed
A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887]Phase 4110 participants (Anticipated)Interventional2023-01-01Enrolling by invitation
Opioid-Free Shoulder Arthroplasty[NCT03540030]Phase 486 participants (Actual)Interventional2016-09-30Completed
"Preoperative Gabapentin and Its Effects on Postoperative Analgesia in Patients Undergoing Cosmetic Breast Surgery"[NCT05997355]100 participants (Anticipated)Interventional2023-09-01Not yet recruiting
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain: A Multicenter Prospective Study[NCT04798573]10,000 participants (Anticipated)Observational2012-08-03Active, not recruiting
Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543]90 participants (Actual)Interventional2014-06-30Completed
Aprepitant vs. Desloratadine in Non-small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Related Pruritus: A Prospective, Randomized Control, Double-blinded, Phase II Clinical Trial[NCT02646020]Phase 2138 participants (Actual)Interventional2015-12-31Completed
Study of Gabapentin for the Pruritus of Cholestasis[NCT00058890]Phase 315 participants (Actual)Interventional2000-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

ASES

American Shoulder and Elbow Surgeons (ASES) Shoulder Score for pain and function. Range 0-100. Low score = worse shoulder condition. Function, disability, and pain subscores (all ranges 0-50), and are summed for total ASES score. (NCT03540030)
Timeframe: 2 Weeks

Interventionunits on a scale (Median)
Observational54.3
Non-Opioid Intervention54.2

Morphine Use

Morphine milli-equivalents In-hospital post-operative. Continuous scale of MME, no defined better/worse. Measured as number and dose of medications taken. For example, if the patient received an opioid, the drug and dose was recorded and converted to MME. A time frame of when to assess opioid use in-hospital post-operative was not used but was a continuous monitor for rescue opioid from in-hospital post-operative through discharge. (NCT03540030)
Timeframe: In-hospital Stay

InterventionMorphine milli-equivalents (Median)
Observational45.0
Non-Opioid Intervention19.0

Post Op Pain

Pain at patient discharge or 24-hours, whichever comes first - measured on a 0 (no pain) -10 (worst possible pain) numeric rating scale (NRS). A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 24 hours

Interventionscore on a scale (Median)
Observational3.0
Non-Opioid Intervention2.0

Simple Shoulder Test

Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Months

Interventionscore on a scale (Median)
Observational6
Non-Opioid Intervention6

Simple Shoulder Test

Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Weeks

Interventionscore on a scale (Median)
Observational2.0
Non-Opioid Intervention2.0

Additional Post Op Pain

post-operative pain: measured on a 0 (no pain) -10 (worst) numeric rating scale (NRS) at 6hrs, 12hrs, 2 weeks, and 2 months. A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 6hrs, 12hrs, 2weeks, 2 months

,
Interventionscore on a scale (Median)
6 Hrs12 hrs2 weeks2 months
Non-Opioid Intervention0.000.820
Observational241.30.7

Constipation

rate of constipation (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention4274
Observational7212

Constipation

rate of constipation (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention13220
Observational1992

Falls

rate of falls (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention4274
Observational4242

Falls

rate of falls (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention5300
Observational1272

Nausea

rate of nausea (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention1300
Observational0282

Nausea

rate of nausea (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention1340
Observational5232

Pain Satisfaction

Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention2924
Observational2352

Pain Satisfaction

Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention3410
Observational2712

Veterans RAND 12 Item Health Survey (VR-12©) Physical Health Subscore, and Mental Health Subscore

quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Months

,
Interventionscore on a scale (Median)
PCSMCS
Non-Opioid Intervention40.360.8
Observational38.458.7

Veterans RAND 12 Item Health Survey (VR-12©) Physical Health Subscore, and Mental Health Subscore

quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Weeks

,
Interventionscore on a scale (Median)
PCSMCS
Non-Opioid Intervention35.059.1
Observational36.756.3

Reviews

21 reviews available for gabapentin and Itching

ArticleYear
Treatment modalities in brachioradial pruritis: a systematic review.
    Dermatology online journal, 2022, Aug-15, Volume: 28, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Capsaicin; Gabapentin; Humans; Pregabalin; Pruritus; Quality of Li

2022
Gabapentin for uremic pruritus: a systematic review of randomized controlled trials.
    International journal of dermatology, 2020, Volume: 59, Issue:4

    Topics: Dizziness; Gabapentin; Humans; Incidence; Kidney Failure, Chronic; Pruritus; Randomized Controlled T

2020
Notalgia paresthetica treated with low dose of gabapentin: Case report and literature review.
    Dermatologic therapy, 2020, Volume: 33, Issue:2

    Topics: Gabapentin; Humans; Peripheral Nervous System Diseases; Pruritus; Skin Diseases

2020
Post-Burn Pruritus.
    International journal of molecular sciences, 2020, May-29, Volume: 21, Issue:11

    Topics: Animals; Antipsychotic Agents; Burns; Gabapentin; Histamine Antagonists; Humans; Inflammation; Kerat

2020
Recent advances in the treatment of uremic pruritus.
    Current opinion in nephrology and hypertension, 2020, Volume: 29, Issue:5

    Topics: Gabapentin; Humans; Piperidines; Pruritus; Renal Dialysis; Renal Insufficiency, Chronic

2020
How to assess and relieve that perplexing rashless itch.
    The Journal of family practice, 2020, Volume: 69, Issue:9

    Topics: Antipruritics; Chronic Disease; Diagnosis, Differential; Evidence-Based Medicine; Gabapentin; Humans

2020
Treatment of Uremic Pruritus: A Systematic Review.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:5

    Topics: Administration, Cutaneous; Amines; Analgesics; Anti-Asthmatic Agents; Antipruritics; Capsaicin; Crom

2017
Treatment of Uremic Pruritus: A Systematic Review.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:5

    Topics: Administration, Cutaneous; Amines; Analgesics; Anti-Asthmatic Agents; Antipruritics; Capsaicin; Crom

2017
Treatment of Uremic Pruritus: A Systematic Review.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:5

    Topics: Administration, Cutaneous; Amines; Analgesics; Anti-Asthmatic Agents; Antipruritics; Capsaicin; Crom

2017
Treatment of Uremic Pruritus: A Systematic Review.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:5

    Topics: Administration, Cutaneous; Amines; Analgesics; Anti-Asthmatic Agents; Antipruritics; Capsaicin; Crom

2017
Pruritus in Cutaneous T-Cell Lymphoma and Its Management.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Adrenal Cortex Hormones; Amines; Antidepressive Agents, Tricyclic; Antipruritics; Cyclohexanecarboxy

2018
End-Stage Renal Disease Chronic Itch and Its Management.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antipruritics; Chronic Disease; Cyclohexanecarboxylic A

2018
Clinical practice. Chronic pruritus.
    The New England journal of medicine, 2013, Apr-25, Volume: 368, Issue:17

    Topics: Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic A

2013
Uremic pruritus.
    Kidney international, 2015, Volume: 87, Issue:4

    Topics: Acupuncture Therapy; Amines; Anti-Inflammatory Agents; Calcium Channel Blockers; Cyclohexanecarboxyl

2015
A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain.
    Anaesthesia, 2015, Volume: 70, Issue:10

    Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Administration Schedule; D

2015
A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain.
    Anaesthesia, 2015, Volume: 70, Issue:10

    Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Administration Schedule; D

2015
A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain.
    Anaesthesia, 2015, Volume: 70, Issue:10

    Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Administration Schedule; D

2015
A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain.
    Anaesthesia, 2015, Volume: 70, Issue:10

    Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Administration Schedule; D

2015
The Effect of Gabapentin on Acute Postoperative Pain in Patients Undergoing Total Knee Arthroplasty: A Meta-Analysis.
    Medicine, 2016, Volume: 95, Issue:20

    Topics: Amines; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids

2016
Gabapentin and pregabalin for the treatment of chronic pruritus.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:3

    Topics: Amines; Anti-Anxiety Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma

2016
The efficacy of preoperative administration of gabapentin/pregabalin in improving pain after total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, 08-30, Volume: 17, Issue:1

    Topics: Amines; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Dizziness; Gabapent

2016
Itch Management: Systemic Agents.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Amines; Analgesics; Analgesics, Opioid; Anion Exchange Resins; Antidepressive Agents; Aprepitant; Ch

2016
Neurologic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Acupuncture Therapy; Amines; Anesthetics, Local; Anticonvulsants; Antipruritics; Botulinum Toxins, T

2016
Uremic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Acupuncture Therapy; Amines; Analgesics, Opioid; Anticonvulsants; Calcineurin Inhibitors; Cyclohexan

2016
Post burn pruritus--a review of current treatment options.
    Burns : journal of the International Society for Burn Injuries, 2012, Volume: 38, Issue:5

    Topics: Amines; Analgesics; Burns; Cyclohexanecarboxylic Acids; Emollients; Gabapentin; gamma-Aminobutyric A

2012
Single dose of gabapentin for prophylaxis intrathecal morphine-induced pruritus in orthopedic surgery: a randomized controlled trial.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95, Issue:2

    Topics: Adolescent; Adult; Aged; Amines; Analgesics, Opioid; Anesthesia, Spinal; Antipruritics; Cyclohexanec

2012
Gabapentin for pruritus in palliative care.
    The American journal of hospice & palliative care, 2013, Volume: 30, Issue:2

    Topics: Amines; Analgesics, Opioid; Burns; Cholestasis; Cyclohexanecarboxylic Acids; Dermatologic Agents; Ga

2013

Trials

19 trials available for gabapentin and Itching

ArticleYear
Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis.
    Journal of orthopaedic surgery and research, 2021, Nov-15, Volume: 16, Issue:1

    Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Gabapentin; Humans; Kyphosis; Morphin

2021
Topical gabapentin 10% in the treatment of epidermolysis bullosa pruritus: A pilot, double-blind, split-site, randomized controlled trial.
    Dermatologic therapy, 2022, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Child; Double-Blind Method; Epidermolysis Bullosa; Female; Gabapentin; Humans; Ma

2022
Randomized trial of two after-dialysis gabapentin regimens for severe uremic pruritus in hemodialysis patients.
    Internal and emergency medicine, 2019, Volume: 14, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Double-Blind Method; Female; Gabapentin; Humans; Male; M

2019
Comparison of gabapentin and hydroxyzine in the treatment of pruritus in patients on dialysis.
    Clinical and experimental dermatology, 2020, Volume: 45, Issue:7

    Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Antipruritics; Case-Control Studies; Cross-Over St

2020
A randomized controlled study of 6% gabapentin topical formulation for chronic kidney disease-associated pruritus.
    International journal of dermatology, 2020, Volume: 59, Issue:8

    Topics: Double-Blind Method; Gabapentin; Humans; Pruritus; Renal Dialysis; Renal Insufficiency, Chronic; Tre

2020
Comparison of gabapentin and doxepin in the management of uremic pruritus: A randomized crossover clinical trial.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Double-Blind Method; Doxepin; Gabapentin; Histamine Antagonists; Humans; Pruritus; Quality of Life;

2020
Gabapentin versus dexchlorpheniramine as treatment for uremic pruritus: a randomised controlled trial.
    European journal of dermatology : EJD, 2018, Aug-01, Volume: 28, Issue:4

    Topics: Aged; Chlorpheniramine; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin;

2018
Uraemic pruritus: relief of itching by gabapentin and pregabalin.
    Nephron. Clinical practice, 2012, Volume: 122, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Comorbidity; Cyclohexanecarboxylic Acids; Dose-R

2012
Gabapentin: A promising therapy for uremic pruritus in hemodialysis patients: A randomized-controlled trial and review of literature.
    The Journal of dermatological treatment, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagon

2016
Gabapentin and uremic pruritus in hemodialysis patients.
    Renal failure, 2009, Volume: 31, Issue:2

    Topics: Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gaba

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Can gabapentin help reduce postoperative pain in arthroscopic rotator cuff repair? A prospective, randomized, double-blind study.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2010, Volume: 26, Issue:9 Suppl

    Topics: Aged; Amines; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Arthrosc

2010
A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus.
    Burns : journal of the International Society for Burn Injuries, 2011, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Amines; Analgesics; Burns; Cetirizine; Child; Cyclohexanecarboxylic Acids;

2011
Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin.
    Jornal brasileiro de nefrologia, 2012, Volume: 34, Issue:2

    Topics: Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histam

2012
Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study.
    Nephrology (Carlton, Vic.), 2012, Volume: 17, Issue:8

    Topics: Adult; Aged; Amines; Analgesics; Antipruritics; Chi-Square Distribution; Cross-Over Studies; Cyclohe

2012
Gabapentin therapy for pruritus in haemodialysis patients: a randomized, placebo-controlled, double-blind trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:12

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans

2004
Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:5

    Topics: Adult; Amines; Analgesics; Cholestasis; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind M

2006
Gabapentin: a promising drug for the treatment of uremic pruritus.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2007, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Ga

2007
Preoperative gabapentin prevents intrathecal morphine-induced pruritus after orthopedic surgery.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:6

    Topics: Adult; Amines; Anesthesia, Spinal; Anesthetics, Local; Antipruritics; Bupivacaine; Cyclohexanecarbox

2008

Other Studies

34 other studies available for gabapentin and Itching

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Evaluation of Gabapentin and Transforaminal Corticosteroid Injections for Brachioradial Pruritus.
    JAMA dermatology, 2022, 09-01, Volume: 158, Issue:9

    Topics: Adrenal Cortex Hormones; Cervical Vertebrae; Gabapentin; Humans; Pruritus

2022
Gabapentin and oral antidepressants for chronic pruritus: a prospective cohort study evaluating efficacy and side effects in daily dermatological practice.
    The Journal of dermatological treatment, 2023, Volume: 34, Issue:1

    Topics: Adult; Amines; Antidepressive Agents; Cohort Studies; Cyclohexanecarboxylic Acids; Drug-Related Side

2023
Gabapentin treatment in notalgia paresthetica: a preliminary report.
    International journal of dermatology, 2020, Volume: 59, Issue:4

    Topics: Adult; Back; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; Hum

2020
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy,

2017
Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:2

    Topics: Adolescent; Analgesics; Burns; Child; Child, Preschool; Female; Gabapentin; Humans; Infant; Male; Ne

2018
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
Effect of cold pack therapy for management of burn scar pruritus: A pilot study.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:4

    Topics: Adult; Burns; Cicatrix; Cryotherapy; Excitatory Amino Acid Antagonists; Female; Gabapentin; Histamin

2018
Peripheral gabapentin regulates mosquito allergy-induced itch in mice.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Amines; Animals; Antipruritics; Calcium Channels; Culicidae; Cyclohexanecarboxylic Acids; Gabapentin

2018
Prurigo nodularis: a physician survey to evaluate current perceptions of its classification, clinical experience and unmet need.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Chronic Disease; Gabapentin; Histamine Antagonists; Huma

2018
Use of Systemic Treatment in Patients with Chronic Pruritus: A Survey of Dermatologists in the Netherlands.
    Acta dermato-venereologica, 2019, Mar-01, Volume: 99, Issue:3

    Topics: Adult; Antidepressive Agents; Antipruritics; Chronic Disease; Dermatologists; Drug Prescriptions; Fe

2019
Episodic itch in a case of spinal glioma.
    BMC neurology, 2013, Sep-23, Volume: 13

    Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Evoked Potentials, Somatosensory; Female; Gab

2013
Uremic pruritus is improved by gabapentin.
    International journal of dermatology, 2014, Volume: 53, Issue:9

    Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric A

2014
Efficacy and safety of gabapentin for uremic pruritus and restless legs syndrome in conservatively managed patients with chronic kidney disease.
    Journal of pain and symptom management, 2015, Volume: 49, Issue:4

    Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-

2015
Investigation of the pruritus-induced functional activity in the rat brain using manganese-enhanced MRI.
    Journal of magnetic resonance imaging : JMRI, 2015, Volume: 42, Issue:3

    Topics: Amines; Animals; Animals, Newborn; Brain; Brain Mapping; Capsaicin; Contrast Media; Cyclohexanecarbo

2015
[Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2015, Volume: 31, Issue:3

    Topics: Amines; Analgesics; Ascorbic Acid; Burns; Cetirizine; Cicatrix; Cyclohexanecarboxylic Acids; Gabapen

2015
Multilevel symmetric neuropathic pruritus (MSNP) presenting as recalcitrant "generalized" pruritus.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:4

    Topics: Age Distribution; Aged; Amines; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Diseas

2016
Small Fiber Neuropathy in Children: Two Case Reports Illustrating the Importance of Recognition.
    Pediatrics, 2016, Volume: 138, Issue:4

    Topics: Adolescent; Amines; Analgesics; Biopsy; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Eryth

2016
Brachioradial pruritus successfully treated with gabapentin.
    The Journal of dermatology, 2010, Volume: 37, Issue:7

    Topics: Amines; Cyclohexanecarboxylic Acids; Dermatologic Agents; Forearm; Gabapentin; gamma-Aminobutyric Ac

2010
Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin.
    Acta dermato-venereologica, 2010, Volume: 90, Issue:6

    Topics: Administration, Cutaneous; Amines; Analgesics; Antipruritics; Cyclohexanecarboxylic Acids; Drug Ther

2010
A case of post-herpetic itch resolved with gabapentin.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:1

    Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zost

2011
[Brachioradial pruritus effectively treated with gabapentin].
    Ugeskrift for laeger, 2012, Jun-25, Volume: 174, Issue:26

    Topics: Amines; Antipruritics; Arm; Brachial Plexus Neuropathies; Cervical Vertebrae; Cyclohexanecarboxylic

2012
Brachioradial pruritus: response to treatment with gabapentin.
    The British journal of dermatology, 2004, Volume: 150, Issue:4

    Topics: Acetates; Aged; Amines; Arm; Cyclohexanecarboxylic Acids; Dermatologic Agents; Female; Gabapentin; g

2004
Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.
    Burns : journal of the International Society for Burn Injuries, 2004, Volume: 30, Issue:8

    Topics: Adolescent; Amines; Antipruritics; Burns; Child; Child Behavior Disorders; Child, Preschool; Cyclohe

2004
[Brachioradial pruritus: a rare, localized, neuropathic form of itching].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:6

    Topics: Amines; Anticonvulsants; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Female; Forearm; Gabapenti

2006
Gabapentin for uraemic pruritus.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:6

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Prurit

2005
Efficacy of gabapentin in the management of pruritus of unknown origin.
    Archives of dermatology, 2005, Volume: 141, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amino

2005
Mirtazapine and gabapentin for reducing pruritus in cutaneous T-cell lymphoma.
    Journal of the American Academy of Dermatology, 2006, Volume: 55, Issue:3

    Topics: Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin;

2006
Uremic pruritus.
    The International journal of artificial organs, 2006, Volume: 29, Issue:10

    Topics: Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Capsaicin; Cyclohexanecarboxylic Acids; Gabape

2006
Gabapentin use in chronic uraemic itch is in line with emerging pathogenetic hypothesis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:12

    Topics: Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; P

2007
Gabapentin treatment for notalgia paresthetica, a common isolated peripheral sensory neuropathy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:10

    Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric A

2007
Gabapentin as a therapeutic option in uremic pruritus.
    Kidney international, 2008, Volume: 73, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Prurit

2008
Role of gabapentin in the treatment of uremic pruritus.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:7

    Topics: Amines; Antipruritics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kid

2008
Gabapentin treatment for brachioradial pruritus.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1999, Volume: 13, Issue:3

    Topics: Acetates; Administration, Oral; Amines; Arm; Cyclohexanecarboxylic Acids; Drug Administration Schedu

1999