gabapentin has been researched along with HIV Coinfection in 16 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to assess the efficacy and safety of Gabapentin as the sole analgesic in patients with HIV-related painful neuropathy." | 7.71 | Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations. ( Bottura, P; La Spina, I; Maggiolo, F; Porazzi, D; Suter, F, 2001) |
| "Neuropathic pain is commonly associated with affective disorders such as anxiety and depression." | 5.35 | Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. ( Blackbeard, J; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC, 2008) |
| " Acute morphine or gabapentin treatment partly attenuated allodynia in males, but not females." | 4.12 | Persistent sensory changes and sex differences in transgenic mice conditionally expressing HIV-1 Tat regulatory protein. ( Bagdas, D; Bigbee, J; Caillaud, M; Damaj, MI; Hauser, KF; Knapp, PE; McKiver, B; Nass, SR; Ondo, O; Paris, JJ; Toma, W; Warncke, UO, 2022) |
| "Gabapentin is commonly prescribed for chronic pain, including to patients with HIV (PWH)." | 4.12 | Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV. ( Barry, DT; Becker, WC; Crystal, S; Edelman, EJ; Gordon, KS; Kerns, RD; Li, Y; Marshall, BDL; Oldfield, BJ; Rentsch, CT; Vickers-Smith, R, 2022) |
| " Two distinct FAAH inhibitory compounds, URB597 and PF-3845 were tested, and contrasted with standard antinociceptive gabapentin or vehicle treatment, for attenuation of tactile allodynia, cold allodynia, and mechanical hyperalgesia." | 3.81 | Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy. ( Jergova, S; Nasirinezhad, F; Pearson, JP; Sagen, J, 2015) |
| "The objective of this study was to assess the efficacy and safety of Gabapentin as the sole analgesic in patients with HIV-related painful neuropathy." | 3.71 | Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations. ( Bottura, P; La Spina, I; Maggiolo, F; Porazzi, D; Suter, F, 2001) |
| " Recent evidence suggests safety concerns associated with gabapentin including adverse neurologic effects." | 1.56 | Safety of Gabapentin Prescribed for Any Indication in a Large Clinical Cohort of 571,718 US Veterans with and without Alcohol Use Disorder. ( Bryant, KJ; Fiellin, DA; Justice, AC; Morford, KL; Rentsch, CT; Tate, JP, 2020) |
| "Treatment with gabapentin, but not amitriptyline, was associated with a complete attenuation of hind paw mechanical hypersensitivity observed with indinavir treatment." | 1.46 | A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy. ( Bennett, DLH; Calvo, M; Huang, W; Pheby, T; Rice, ASC, 2017) |
| "Spinal epidural lipomatosis is a rare condition of adipose tissue hypertrophy in the epidural space." | 1.38 | Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy. ( Billings, F; Hoyt, MR, 2012) |
| "Neuropathic pain is commonly associated with affective disorders such as anxiety and depression." | 1.35 | Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. ( Blackbeard, J; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, TW | 1 |
| Samet, JH | 1 |
| Lodi, S | 1 |
| Kimmel, SD | 1 |
| Forman, LS | 1 |
| Lira, MC | 1 |
| Liebschutz, JM | 1 |
| Williams, EC | 1 |
| Walley, AY | 1 |
| Toma, W | 1 |
| Paris, JJ | 1 |
| Warncke, UO | 1 |
| Nass, SR | 1 |
| Caillaud, M | 1 |
| McKiver, B | 1 |
| Ondo, O | 1 |
| Bagdas, D | 1 |
| Bigbee, J | 1 |
| Knapp, PE | 1 |
| Hauser, KF | 1 |
| Damaj, MI | 1 |
| Rentsch, CT | 2 |
| Morford, KL | 1 |
| Fiellin, DA | 1 |
| Bryant, KJ | 1 |
| Justice, AC | 1 |
| Tate, JP | 1 |
| Oldfield, BJ | 1 |
| Li, Y | 1 |
| Vickers-Smith, R | 1 |
| Becker, WC | 1 |
| Barry, DT | 1 |
| Crystal, S | 1 |
| Gordon, KS | 1 |
| Kerns, RD | 1 |
| Marshall, BDL | 1 |
| Edelman, EJ | 1 |
| Egan, KE | 1 |
| Caldwell, GM | 1 |
| Eckmann, MS | 1 |
| Nasirinezhad, F | 1 |
| Jergova, S | 1 |
| Pearson, JP | 1 |
| Sagen, J | 1 |
| Huang, W | 1 |
| Calvo, M | 1 |
| Pheby, T | 2 |
| Bennett, DLH | 1 |
| Rice, ASC | 1 |
| Wallace, VC | 1 |
| Segerdahl, AR | 1 |
| Blackbeard, J | 1 |
| Rice, AS | 1 |
| Wiersinga, WJ | 1 |
| Prins, JM | 1 |
| van de Beek, D | 1 |
| Billings, F | 1 |
| Hoyt, MR | 1 |
| Skolnick, AA | 1 |
| Manack, L | 1 |
| Rosner, H | 1 |
| Rubin, L | 1 |
| Kestenbaum, A | 1 |
| Newshan, G | 1 |
| Vadivelu, N | 1 |
| Berger, J | 1 |
| Peña, D | 1 |
| Prada, JL | 1 |
| de La Torre, J | 1 |
| del Arco, A | 1 |
| García-Alegría, J | 1 |
| La Spina, I | 1 |
| Porazzi, D | 1 |
| Maggiolo, F | 1 |
| Bottura, P | 1 |
| Suter, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Persistent Postoperative Pain Incidence With Long Term Perioperative Gabapentin Used[NCT02693821] | Phase 4 | 122 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gabapentin and HIV Coinfection
| Article | Year |
|---|---|
HIV Neuropathy-a Review of Mechanisms, Diagnosis, and Treatment of Pain.
Topics: Anesthetics, Local; Gabapentin; HIV Infections; Humans; Neuralgia; Neurologic Examination; Pregabali | 2021 |
[Gabapentin in the treatment of polyneuropathy associated with the human immunodeficiency virus].
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric | 1999 |
1 trial available for gabapentin and HIV Coinfection
| Article | Year |
|---|---|
Gabapentin adjunctive therapy in neuropathic pain states.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapen | 1996 |
13 other studies available for gabapentin and HIV Coinfection
| Article | Year |
|---|---|
Functional Impairment and Cognitive Symptoms Among People with HIV Infection on Chronic Opioid Therapy for Pain: The Impact of Gabapentin and Other Sedating Medications.
Topics: Analgesics, Opioid; Chronic Pain; Cognition; Cross-Sectional Studies; Gabapentin; HIV Infections; Hu | 2022 |
Persistent sensory changes and sex differences in transgenic mice conditionally expressing HIV-1 Tat regulatory protein.
Topics: Animals; Cryopyrin-Associated Periodic Syndromes; Doxycycline; Female; Gabapentin; Gene Products, ta | 2022 |
Safety of Gabapentin Prescribed for Any Indication in a Large Clinical Cohort of 571,718 US Veterans with and without Alcohol Use Disorder.
Topics: Accidental Falls; Alcoholism; Cohort Studies; Comorbidity; Confusion; Drug Interactions; Excitatory | 2020 |
Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV.
Topics: Analgesics, Opioid; Chronic Pain; Cohort Studies; Gabapentin; HIV Infections; Humans; Opioid-Related | 2022 |
Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy.
Topics: Amidohydrolases; Amines; Analgesics; Animals; Benzamides; Carbamates; Cyclohexanecarboxylic Acids; D | 2015 |
A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy.
Topics: Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Binding Proteins; Cyclohexanec | 2017 |
Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain.
Topics: Amines; Analgesics; Animal Diseases; Animals; Anxiety; Behavior, Animal; Cyclohexanecarboxylic Acids | 2008 |
Therapy-resistant opsoclonus-myoclonus syndrome secondary to HIV-1 infection.
Topics: Adult; Amines; Anti-HIV Agents; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Excitatory Am | 2012 |
Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, N | 2012 |
Science reporters hear wide range of recent data at 12th annual conference.
Topics: Acetates; Aged; AIDS Vaccines; American Medical Association; Amines; Animals; Anticonvulsants; beta- | 1993 |
HIV neuropathy treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci | 1998 |
Neuropathic pain after anti-HIV gene therapy successfully treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci | 1999 |
Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami | 2001 |