Page last updated: 2024-10-27

gabapentin and Guillain-Barre Syndrome

gabapentin has been researched along with Guillain-Barre Syndrome in 12 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Guillain-Barre Syndrome: An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)

Research Excerpts

ExcerptRelevanceReference
"We evaluated the effects of gabapentin and carbamazepine for pain relief in 36 Guillain-Barré syndrome patients."9.11The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit. ( Kumar, A; Navkar, DV; Pandey, CK; Raza, M; Singh, UK; Tripathi, M, 2005)
"Gabapentin, an antiepileptic drug, has been used effectively for different types of pain management."9.10Gabapentin for the treatment of pain in guillain-barré syndrome: a double-blinded, placebo-controlled, crossover study. ( Agarwal, A; Baronia, A; Bose, N; Garg, G; Pandey, CK; Singh, N; Singh, PK; Singh, U, 2002)
"His pain was scored as a five on a six-point visual analog scale, and it persisted despite routine supportive therapy."6.50[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl]. ( Anzai, S; Hashimoto, Y; Nagasawa, K; Suzuki, T, 2014)
"We evaluated the effects of gabapentin and carbamazepine for pain relief in 36 Guillain-Barré syndrome patients."5.11The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit. ( Kumar, A; Navkar, DV; Pandey, CK; Raza, M; Singh, UK; Tripathi, M, 2005)
"Gabapentin, an antiepileptic drug, has been used effectively for different types of pain management."5.10Gabapentin for the treatment of pain in guillain-barré syndrome: a double-blinded, placebo-controlled, crossover study. ( Agarwal, A; Baronia, A; Bose, N; Garg, G; Pandey, CK; Singh, N; Singh, PK; Singh, U, 2002)
"Pain was rated on a scale from 0 (no pain) to 10 (maximum pain)."2.52Pharmacological treatment for pain in Guillain-Barré syndrome. ( Liu, J; McNicol, ED; Wang, LN, 2015)
"Gabapentin is a reasonable first-line choice, and opioid medications can be added for more severe pain but there are few clinical trials to inform specific recommendations."2.52Headache and Pain in Guillain-Barré Syndrome. ( Farmakidis, C; Herskovitz, S; Inan, S; Milstein, M, 2015)
"His pain was scored as a five on a six-point visual analog scale, and it persisted despite routine supportive therapy."2.50[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl]. ( Anzai, S; Hashimoto, Y; Nagasawa, K; Suzuki, T, 2014)
"Pain was rated on a scale from 0 (no pain) to 10 (maximum pain)."2.49Pharmacological treatment for pain in Guillain-Barré syndrome. ( Liu, J; McNicol, ED; Wang, LN, 2013)
"Guillain-Barré syndrome may result in hypertensive encephalopathy that can manifest as status epilepticus before the onset of motor symptoms."1.34Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome. ( Abend, NS; Bonnemann, CG; Licht, DJ, 2007)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's7 (58.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Korem, S1
Gandhi, H1
Dayag, DB1
Liu, J2
Wang, LN2
McNicol, ED2
Peña, L1
Moreno, CB1
Gutierrez-Alvarez, AM1
Suzuki, T1
Hashimoto, Y1
Anzai, S1
Nagasawa, K1
Farmakidis, C1
Inan, S1
Milstein, M1
Herskovitz, S1
Schleich, A1
Baumann, H1
Maguire, GA1
Bird, AA1
Pandey, CK2
Bose, N1
Garg, G1
Singh, N1
Baronia, A1
Agarwal, A1
Singh, PK1
Singh, U1
Hernández, JL1
Pajarón, M1
García-Regata, O1
Jiménez, V1
González-Macías, J1
Ramos-Estébanez, C1
Raza, M1
Tripathi, M1
Navkar, DV1
Kumar, A1
Singh, UK1
Abend, NS1
Bonnemann, CG1
Licht, DJ1

Reviews

6 reviews available for gabapentin and Guillain-Barre Syndrome

ArticleYear
Pharmacological treatment for pain in Guillain-Barré syndrome.
    The Cochrane database of systematic reviews, 2013, Oct-20, Issue:10

    Topics: Amines; Analgesics; Carbamazepine; Constipation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amin

2013
Pain management in Guillain-Barre syndrome: a systematic review.
    Neurologia (Barcelona, Spain), 2015, Volume: 30, Issue:7

    Topics: Amines; Analgesics; Anti-Inflammatory Agents; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin

2015
[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl].
    No to hattatsu = Brain and development, 2014, Volume: 46, Issue:4

    Topics: Acetaminophen; Amines; Child; Cyclohexanecarboxylic Acids; Drug Combinations; Fentanyl; Gabapentin;

2014
Pharmacological treatment for pain in Guillain-Barré syndrome.
    The Cochrane database of systematic reviews, 2015, Apr-09, Issue:4

    Topics: Amines; Analgesics; Carbamazepine; Constipation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amin

2015
Headache and Pain in Guillain-Barré Syndrome.
    Current pain and headache reports, 2015, Volume: 19, Issue:8

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Sy

2015
Gabapentin for intractable hiccup.
    The American journal of medicine, 2004, Aug-15, Volume: 117, Issue:4

    Topics: Acetates; Aged; Amines; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therap

2004

Trials

2 trials available for gabapentin and Guillain-Barre Syndrome

ArticleYear
Gabapentin for the treatment of pain in guillain-barré syndrome: a double-blinded, placebo-controlled, crossover study.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:6

    Topics: Acetates; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind M

2002
The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:1

    Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Conscious Sedation; Crit

2005

Other Studies

4 other studies available for gabapentin and Guillain-Barre Syndrome

ArticleYear
Guillain-Barré syndrome associated with COVID-19 disease.
    BMJ case reports, 2020, Sep-21, Volume: 13, Issue:9

    Topics: Analgesics; Betacoronavirus; Brain; Coronavirus Infections; COVID-19; Diagnosis, Differential; Femal

2020
[Disease with generalized pain. Guillain-Barré syndrome].
    Praxis, 2011, Apr-13, Volume: 100, Issue:8

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin;

2011
Gabapentin for treating acquired neurogenic stuttering.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2012, Volume: 24, Issue:3

    Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; g

2012
Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome.
    Pediatric emergency care, 2007, Volume: 23, Issue:9

    Topics: Adolescent; Amines; Anticonvulsants; Antihypertensive Agents; Cyclohexanecarboxylic Acids; Diagnosis

2007