gabapentin has been researched along with Genital Diseases, Female in 1 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Genital Diseases, Female: Pathological processes involving the female reproductive tract (GENITALIA, FEMALE).
Excerpt | Relevance | Reference |
---|---|---|
"Gabapentin was associated with increased dizziness, but it significantly reduced the use of antiemetic at any time in the first 24 postoperative hours." | 2.90 | A Triple-Blind Randomized Trial of Preemptive Use of Gabapentin Before Laparoscopic Hysterectomy for Benign Gynaecologic Conditions. ( Al-Malki, G; Ballesteros, LER; Krishnamurthy, S; Mansour, F; Moore, A; Suarthana, E; Tulandi, T, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tulandi, T | 1 |
Krishnamurthy, S | 1 |
Mansour, F | 1 |
Suarthana, E | 1 |
Al-Malki, G | 1 |
Ballesteros, LER | 1 |
Moore, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Use of Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy: Evaluation of Postoperative Pain and Opioid Consumption[NCT04495374] | Phase 4 | 58 participants (Actual) | Interventional | 2019-09-02 | Terminated (stopped due to Due to an atypical health scenario caused by the COVID-19 pandemic) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Evaluation of the number of intravenous opioid doses used within 24 hours of postoperative abdominal hysterectomy surgery in patients who used pregabalin 300mg or not as preemptive analgesia (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
Intervention | number of doses (Median) |
---|---|
Group P(0) - Placebo | 4 |
Group P(1) - Pregabalin 300mg | 2 |
• Assess the presence of adverse effects such as nausea and vomiting, itching and dizziness, comparing the intervention group that used pregabalin with the placebo group (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery) and also immediately in the post-anesthetic recovery room
Intervention | Participants (Count of Participants) |
---|---|
Group P(0) - Placebo | 7 |
Group P(1) - Pregabalin 300mg | 16 |
Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single 300mg dose of pregabalin or placebo as preemptive analgesia, using the McGill pain questionnaire, which consists of 20 word groups , and each group can contain from 2 to 6 descriptive words, these descriptors are placed in an increasing order of magnitude in relation to the intensity. The left of each word has a numerical value in an attempt to represent the intensity of the descriptor. For the analysis of the answers, the total number of words chosen in each subgroup by the patient was used to qualify his pain, the minimum value being equal to 0 (zero), if the patient chose not to choose any descriptor, and the maximum value would be 20, as the patient can choose only one descriptor for each subgroup. The quantitative pain index was also evaluated, which represents the sum of the values of each descriptor chosen by the patient, with a minimum value of 0 and a maximum of 78. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
Intervention | score on a scale (Median) |
---|---|
Group P(0) - Placebo | 28.5 |
Group P(1) - Pregabalin 300mg | 12 |
Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single dose of pregabalin 300mg or placebo as preemptive analgesia, using the visual analog scale (VAS) consisting of a 10 cm (cm) line ) graduated in natural number intervals, starting at 0 (zero) until reaching 10 (ten), associated with the numbers, drawings related to the pain presented by the patient at the moment, in which the absence of pain (0 ) there is a happy face, and as the numerical value increases, the drawn face will represent the intensity of pain, up to the value of 10, where a face with crying characteristics is found, indicating greater pain. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
Intervention | score on a scale (Mean) |
---|---|
Group P(0) - Placebo | 7 |
Group P(1) - Pregabalin 300mg | 4 |
Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single dose of pregabalin 300mg or placebo as preemptive analgesia, using the visual analog scale (VAS) consisting of a 10 cm (cm) line ) graduated in natural number intervals, starting at 0 (zero) until reaching 10 (ten), associated with the numbers, drawings related to the pain presented by the patient at the moment, in which the absence of pain (0 ) there is a happy face, and as the numerical value increases, the drawn face will represent the intensity of pain, up to the value of 10, where a face with crying characteristics is found, indicating greater pain. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
Intervention | score on a scale (Mean) |
---|---|
Group P(0) - Placebo | 5 |
Group P(1) - Pregabalin 300mg | 2 |
• Evaluation of the time between the end of abdominal hysterectomy surgery and the patient's request for the use of the first dose of intravenous opioid as an analgesic rescue, comparing between patients who used or not pregabalin 300mg as preemptive analgesia (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
Intervention | Time in minutes (Median) |
---|---|
Group P(0) - Placebo | 170 |
Group P(1) - Pregabalin 300mg | 106 |
1 trial available for gabapentin and Genital Diseases, Female
Article | Year |
---|---|
A Triple-Blind Randomized Trial of Preemptive Use of Gabapentin Before Laparoscopic Hysterectomy for Benign Gynaecologic Conditions.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Genital Diseases, Fe | 2019 |