Page last updated: 2024-10-27

gabapentin and Gangliosidoses, GM2

gabapentin has been researched along with Gangliosidoses, GM2 in 2 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Gangliosidoses, GM2: A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.

Research Excerpts

ExcerptRelevanceReference
" A dramatic response of the severe dysesthesias to amitriptyline and gabapentin is described."3.71Late-onset GM2 gangliosidosis presenting as burning dysesthesias. ( Banwell, BL; Chow, GC; Clarke, JT, 2001)
"Disappearance of the myokymia and improvement in the ataxia were attained with the use of the GABAergic drugs gabapentin and tiagabine."1.31[Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs]. ( Benavente Aguilar, I; Gazulla Abío, J, 2002)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chow, GC1
Clarke, JT1
Banwell, BL1
Gazulla Abío, J1
Benavente Aguilar, I1

Other Studies

2 other studies available for gabapentin and Gangliosidoses, GM2

ArticleYear
Late-onset GM2 gangliosidosis presenting as burning dysesthesias.
    Pediatric neurology, 2001, Volume: 25, Issue:1

    Topics: Acetates; Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexa

2001
[Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs].
    Neurologia (Barcelona, Spain), 2002, Volume: 17, Issue:3

    Topics: Acetates; Adult; Amines; Ataxia; beta-N-Acetylhexosaminidases; Cerebellum; Cyclohexanecarboxylic Aci

2002