Page last updated: 2024-10-27

gabapentin and Fatigue

gabapentin has been researched along with Fatigue in 4 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Fifty patients with refractory partial seizures took part in a prospective, observational study of adjuvant gabapentin (GBP) in increasing doses."5.08High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients. ( Brodie, MJ; Forrest, G; Sills, GJ; Wilson, EA, 1998)
"Gabapentin is an anticonvulsant drug that has analgesic properties for acute postoperative pain."2.74The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study. ( Aykac, B; Bingol, CA; Karlikaya, G; Sayin, M; Türe, H; Türe, U, 2009)
"A total of 578 women with breast cancer were managed at the Menopausal Symptoms After Cancer Clinic between January 2003 and December 2008."1.36The multidisciplinary management of menopausal symptoms after breast cancer: a unique model of care. ( Doherty, DA; Emery, LI; Gregson, J; Hickey, M; Saunders, CM, 2010)
"Anxiety and depression are often also present."1.35Fibromyalgia: poorly understood; treatments are disappointing. ( , 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Türe, H1
Sayin, M1
Karlikaya, G1
Bingol, CA1
Aykac, B1
Türe, U1
Hickey, M1
Emery, LI1
Gregson, J1
Doherty, DA1
Saunders, CM1
Wilson, EA1
Sills, GJ1
Forrest, G1
Brodie, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903]Phase 477 participants (Actual)Interventional2018-05-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"VAS Score 1: How Much Pain do You Feel in Your Operative Site When Resting?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)

Interventionscore on 10-point scale (Mean)
Standard of Care2.26
Postoperative Gabapentin Regimen2.46

"VAS Score 2: How Much Pain do You Feel in Your Operative Site When Moving?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care3.84
Postoperative Gabapentin Regimen3.54

"VAS Score 3: How Well Are You Sleeping?"

Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care5.73
Postoperative Gabapentin Regimen6.38

"VAS Score 4: How Bad is Your Nausea?"

Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care0.36
Postoperative Gabapentin Regimen0.17

"VAS Score 5: How Satisfied Are You With Your Pain Management?"

Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care7.83
Postoperative Gabapentin Regimen8.48

Days Taking Opioids

Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventiondays (Mean)
Standard of Care14.8
Postoperative Gabapentin Regimen18.7

Opioid Consumption

Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).

Interventionmorphine equivalents (Mean)
Standard of Care287.0
Postoperative Gabapentin Regimen281.1

Trials

2 trials available for gabapentin and Fatigue

ArticleYear
The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid;

2009
High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients.
    Epilepsy research, 1998, Volume: 29, Issue:2

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diarrhea; D

1998

Other Studies

2 other studies available for gabapentin and Fatigue

ArticleYear
Fibromyalgia: poorly understood; treatments are disappointing.
    Prescrire international, 2009, Volume: 18, Issue:102

    Topics: Acetaminophen; Acupuncture Therapy; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Ant

2009
The multidisciplinary management of menopausal symptoms after breast cancer: a unique model of care.
    Menopause (New York, N.Y.), 2010, Volume: 17, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Amines; Anti-Anxiety Agents; Breast Neop

2010