Page last updated: 2024-10-27

gabapentin and Esophageal Reflux

gabapentin has been researched along with Esophageal Reflux in 6 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal reflux-induced chronic cough."9.30Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough. ( Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M, 2019)
" Both high and low doses of gabapentin administration could reduce cough hypersensitivity exposed to HCl perfusion, attenuate airway inflammatory damage, and inhibit neurogenic inflammation by reducing SP expression from the airway and vagal ganglia."8.31Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion. ( Chen, R; Chen, Z; Dong, J; Huang, J; Ji, X; Xu, Y; Yan, W; Zhan, C; Zheng, Z; Zhi, H; Zhong, M, 2023)
"The current study was undertaken to evaluate the effect of combined therapy of gabapentin and pantoprazole against forestomach and pylorus ligation-induced gastric esophageal reflux disease (GERD) in albino Wistar rats."7.96Combined therapy of gabapentin with pantoprazole exhibited better protective action against forestomach and pylorus ligation-induced gastric esophageal reflux disease in albino Wistar rats. ( Arya, P; Kaithwas, G, 2020)
"To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal reflux-induced chronic cough."5.30Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough. ( Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M, 2019)
" Both high and low doses of gabapentin administration could reduce cough hypersensitivity exposed to HCl perfusion, attenuate airway inflammatory damage, and inhibit neurogenic inflammation by reducing SP expression from the airway and vagal ganglia."4.31Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion. ( Chen, R; Chen, Z; Dong, J; Huang, J; Ji, X; Xu, Y; Yan, W; Zhan, C; Zheng, Z; Zhi, H; Zhong, M, 2023)
"The current study was undertaken to evaluate the effect of combined therapy of gabapentin and pantoprazole against forestomach and pylorus ligation-induced gastric esophageal reflux disease (GERD) in albino Wistar rats."3.96Combined therapy of gabapentin with pantoprazole exhibited better protective action against forestomach and pylorus ligation-induced gastric esophageal reflux disease in albino Wistar rats. ( Arya, P; Kaithwas, G, 2020)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Zhi, H1
Zhong, M1
Huang, J1
Zheng, Z1
Ji, X1
Xu, Y1
Dong, J1
Yan, W1
Chen, Z1
Zhan, C1
Chen, R1
Arya, P1
Kaithwas, G1
Dong, R2
Xu, X2
Yu, L2
Ding, H1
Pan, J1
Yu, Y1
Shi, C1
Chen, Q1
Zhang, M1
Lv, H1
Qiu, Z2
Naik, RD1
Vaezi, MF1
Sheen, VL1
Ohaegbulam, C1
Rencus, T1
Tandon, D1

Trials

1 trial available for gabapentin and Esophageal Reflux

ArticleYear
Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough.
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:6

    Topics: Adult; Analgesics; Baclofen; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Follo

2019

Other Studies

5 other studies available for gabapentin and Esophageal Reflux

ArticleYear
Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion.
    European journal of pharmacology, 2023, Nov-15, Volume: 959

    Topics: Animals; Cough; Gabapentin; Gastroesophageal Reflux; Guinea Pigs; Hydrochloric Acid; Lung; Neurogeni

2023
Combined therapy of gabapentin with pantoprazole exhibited better protective action against forestomach and pylorus ligation-induced gastric esophageal reflux disease in albino Wistar rats.
    Human & experimental toxicology, 2020, Volume: 39, Issue:4

    Topics: Afferent Pathways; Animals; Disease Models, Animal; Drug Therapy, Combination; Gabapentin; Gastric E

2020
Editorial: breaking the cycle of cough in GERD-neuromodulators to the rescue? Authors' reply.
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:9

    Topics: Baclofen; Cough; Gabapentin; Gastroesophageal Reflux; Humans; Neurotransmitter Agents

2019
Editorial: breaking the cycle of cough in GERD-neuromodulators to the rescue?
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:9

    Topics: Baclofen; Cough; Gabapentin; Gastroesophageal Reflux; Humans; Neurotransmitter Agents

2019
Gabapentin-induced exacerbation of myasthenia gravis.
    Muscle & nerve, 2010, Volume: 42, Issue:1

    Topics: Aged; Amines; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagoni

2010