Page last updated: 2024-10-27

gabapentin and Epilepsy, Absence

gabapentin has been researched along with Epilepsy, Absence in 10 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's7 (70.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Posner, E4
French, JA1
Kanner, AM1
Bautista, J1
Abou-Khalil, B1
Browne, T1
Harden, CL1
Theodore, WH1
Bazil, C1
Stern, J1
Schachter, SC1
Bergen, D1
Hirtz, D1
Montouris, GD1
Nespeca, M1
Gidal, B1
Marks, WJ1
Turk, WR1
Fischer, JH1
Bourgeois, B1
Wilner, A1
Faught, RE1
Sachdeo, RC1
Beydoun, A1
Glauser, TA1
Fromm, GH1
Hosford, DA1
Wang, Y1
Trudeau, V1
Myers, S1
LaMoreaux, L1
Anhut, H1
Garofalo, E1
Ebersole, J1
Bassilios, N1
Launay-Vacher, V1
Khoury, N1
Rondeau, E1
Deray, G1
Sraer, JD1
Dufour, F1
Nalecz, KA1
Nalecz, MJ1
Nehlig, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 3: Metabolism of Lamotrigine During Treatment With Oral Contraceptives[NCT00266149]Phase 310 participants Interventional2003-06-30Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for gabapentin and Epilepsy, Absence

ArticleYear
Absence seizures in children.
    Clinical evidence, 2002, Issue:8

    Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximi

2002
Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
    Epilepsia, 2004, Volume: 45, Issue:5

    Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Antipsychotic Agents; Carbamazepine; Child; Clinic

2004
Absence seizures in children.
    Clinical evidence, 2003, Issue:10

    Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabape

2003
Absence seizures in children.
    Clinical evidence, 2004, Issue:11

    Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuxi

2004
Absence seizures in children.
    Clinical evidence, 2005, Issue:13

    Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy,

2005
Gabapentin: discussion.
    Epilepsia, 1994, Volume: 35 Suppl 5

    Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Inv

1994

Trials

1 trial available for gabapentin and Epilepsy, Absence

ArticleYear
Gabapentin in naive childhood absence epilepsy: results from two double-blind, placebo-controlled, multicenter studies.
    Journal of child neurology, 1996, Volume: 11, Issue:6

    Topics: Acetates; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Respon

1996

Other Studies

3 other studies available for gabapentin and Epilepsy, Absence

ArticleYear
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
    Epilepsia, 1997, Volume: 38, Issue:4

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dru

1997
Gabapentin neurotoxicity in a chronic haemodialysis patient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:10

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Epilepsy, Absence;

2001
Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle.
    Journal of neuroscience research, 2001, Dec-01, Volume: 66, Issue:5

    Topics: Acetates; Amines; Amino Acids, Branched-Chain; Animals; Brain; Carbon Monoxide; Cells, Cultured; Cer

2001