Page last updated: 2024-10-27

gabapentin and Dyspareunia

gabapentin has been researched along with Dyspareunia in 5 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Dyspareunia: Recurrent genital pain occurring during, before, or after SEXUAL INTERCOURSE in either the male or the female.

Research Excerpts

ExcerptRelevanceReference
"In this cohort, extended-release gabapentin, as compared with a placebo, did not reduce tampon test pain."5.27Gabapentin for the Treatment of Vulvodynia: A Randomized Controlled Trial. ( Bachmann, GA; Brown, CS; Foster, DC; Wan, J, 2018)
" Therefore, in women with a uterus, it is recommended that physicians prescribe combination therapy only to treat menopausal symptoms such as vasomotor symptoms (hot flashes) and vaginal atrophy, using the smallest effective dosage for the shortest possible duration."2.53Hormone Therapy and Other Treatments for Symptoms of Menopause. ( Crider, M; Hill, DA; Hill, SR, 2016)
"Vulvodynia is a genital pain syndrome occurring in 7% to 8% of women."2.52Vulvodynia. ( Edwards, L, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, CS2
Bachmann, GA2
Wan, J1
Foster, DC2
Wan, JY1
Rawlinson, LA1
Edwards, L1
Hill, DA1
Crider, M1
Hill, SR1
Hey, M1
Wilson, I1
Johnson, MI1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Controlled Trial of Gabapentin in Vulvodynia: Biological Correlates of Response[NCT01301001]230 participants (Actual)Interventional2012-08-31Completed
Comparative Effects of Clinical Pilates Training and Aerobic Exercise on Menopausal Symptoms, Quality of Life, Sleep and Depression[NCT05764031]30 participants (Actual)Interventional2020-12-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Coital Pain

Coital pain on an 11-point Numeric Rating Scale (0 = no pain at all; 10 = worse pain ever), assessed after each sexual intercourse event. The number of sexual intercourse events was averaged during final week of each treatment arm. (NCT01301001)
Timeframe: Week 6 of each treatment arm

Interventionunits on a scale (Mean)
Placebo3.97
Gabapentin3.85

Tampon Test Pain Intensity

Tampon pain on a 11-point Numeric Rating Scale (0 = no pain at all; 10 = worse pain ever). One tampon was inserted each week. Tampon pain was assessed during last week of maintenance phase (7 days). (NCT01301001)
Timeframe: Week 6 for each treatment arm

Interventionunits on a scale (Mean)
Placebo4.29
Gabapentin3.96

Vulvodynia Pain

Overall vulvodynia pain on an 11-point Numeric Rating Scale (0 = no pain at all; 10 = worse pain ever). Pain was assessed daily during the last week of treatment. Daily scores were averaged. (NCT01301001)
Timeframe: Week 6 for each treatment arm

Interventionunits on a scale (Mean)
Placebo2.88
Gabapentin2.71

Reviews

2 reviews available for gabapentin and Dyspareunia

ArticleYear
Vulvodynia.
    Clinical obstetrics and gynecology, 2015, Volume: 58, Issue:1

    Topics: Administration, Cutaneous; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents; Cyclohexan

2015
Hormone Therapy and Other Treatments for Symptoms of Menopause.
    American family physician, 2016, Dec-01, Volume: 94, Issue:11

    Topics: Acupuncture Therapy; Administration, Intravaginal; Amines; Antidepressive Agents; Atrophy; Cyclohexa

2016

Trials

2 trials available for gabapentin and Dyspareunia

ArticleYear
Gabapentin for the Treatment of Vulvodynia: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2018, Volume: 131, Issue:6

    Topics: Adult; Analgesics; Cross-Over Studies; Delayed-Action Preparations; Diagnostic Techniques, Obstetric

2018
Rationale and design of a multicenter randomized clinical trial of extended release gabapentin in provoked vestibulodynia and biological correlates of response.
    Contemporary clinical trials, 2013, Volume: 36, Issue:1

    Topics: Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Do

2013

Other Studies

1 other study available for gabapentin and Dyspareunia

ArticleYear
Stellate ganglion blockade (SGB) for refractory index finger pain - a case report.
    Annals of physical and rehabilitation medicine, 2011, Volume: 54, Issue:3

    Topics: Abdominal Pain; Accidental Falls; Acetaminophen; Adult; Amines; Autonomic Nerve Block; Chronic Disea

2011