Page last updated: 2024-10-27

gabapentin and Dysesthesia

gabapentin has been researched along with Dysesthesia in 29 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"To report a high incidence of oral mucosal dysesthesia occurring in patients on a pilot study of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa) in combination with paclitaxel (Taxol) and external beam radiation therapy for the treatment of locally advanced squamous cell carcinoma of the head and neck."9.13High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers. ( Cooley-Zgela, T; Gius, D; Morris, JC; Sharp, H; Singh, AK; Van Waes, C, 2008)
"The objective of this study was to compare the efficacy and tolerability of gabapentin and amitriptyline monotherapy in painful diabetic neuropathy."9.09Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study. ( Buffa, C; Chiroli, S; Dallocchio, C; Mazzarello, P, 2000)
"Chronic post-sternotomy chest pain and paresthesia (PCPP) are frequently seen and reduce the quality of life."6.74Efficacy of gabapentin versus diclofenac in the treatment of chest pain and paresthesia in patients with sternotomy. ( Biyik, I; Ergene, O; Gülcüler, M; Karabiga, M; Tayyar, N, 2009)
"Paclitaxel can cause an acute pain syndrome (P-APS), considered to be an acute form of neuropathy and chronic chemotherapy-induced peripheral neuropathy (CIPN)."5.22Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial. ( Atherton, PJ; Lafky, J; Loprinzi, CL; Pachman, DR; Ruddy, KJ; Seisler, D; Shinde, SS; Soori, G, 2016)
"To report a high incidence of oral mucosal dysesthesia occurring in patients on a pilot study of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa) in combination with paclitaxel (Taxol) and external beam radiation therapy for the treatment of locally advanced squamous cell carcinoma of the head and neck."5.13High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers. ( Cooley-Zgela, T; Gius, D; Morris, JC; Sharp, H; Singh, AK; Van Waes, C, 2008)
"The objective of this study was to compare the efficacy and tolerability of gabapentin and amitriptyline monotherapy in painful diabetic neuropathy."5.09Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study. ( Buffa, C; Chiroli, S; Dallocchio, C; Mazzarello, P, 2000)
" A dramatic response of the severe dysesthesias to amitriptyline and gabapentin is described."3.71Late-onset GM2 gangliosidosis presenting as burning dysesthesias. ( Banwell, BL; Chow, GC; Clarke, JT, 2001)
"Chronic post-sternotomy chest pain and paresthesia (PCPP) are frequently seen and reduce the quality of life."2.74Efficacy of gabapentin versus diclofenac in the treatment of chest pain and paresthesia in patients with sternotomy. ( Biyik, I; Ergene, O; Gülcüler, M; Karabiga, M; Tayyar, N, 2009)
"Gabapentin was prescribed to 60 consecutive out-patients with refractory pain persisting at four weeks or more after thoracic surgery or trauma."2.72The use of gabapentin for post-operative and post-traumatic pain in thoracic surgery patients. ( Lee, TW; Sihoe, AD; Thung, KH; Wan, IY; Yim, AP, 2006)
"Scalp dysesthesia is characterized by abnormal sensations of the scalp in the absence of any other unusual physical examination findings."1.39Scalp dysesthesia related to cervical spine disease. ( English, JC; Thornsberry, LA, 2013)
"Neuropathic and/or neuralgic facial pain occurred in 50% (n = 7)."1.35The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions. ( Garza, I, 2008)
"GBP increases the risk of myoclonus in ESRD."1.33Gabapentin-induced myoclonus in end-stage renal disease. ( Bell, WL; Glenn, DG; O'Donovan, CA; Zhang, C, 2005)
"Two patients experienced paresthesias in all digits of the hands, glove-like numbness of the hands and forearm, weakness (unable to open jars), hand clumsiness, upper extremity coldness, fullness or tightness, deep aching pain, and other signs and symptoms consistent with T4 syndrome."1.33Clinical presentation, quantitative sensory testing, and therapy of 2 patients with fourth thoracic syndrome. ( Mellick, GA; Mellick, LB, 2006)
"Treatment with gabapentin was associated with a substantial decrease in pain, which relapsed after tapering the medication."1.30Gabapentin for the treatment of dysesthetic pain after reconstructive surgery. ( Otley, CC, 1999)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.45)18.2507
2000's15 (51.72)29.6817
2010's10 (34.48)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Oliveira, ADP1
Silva-Néto, RP1
Uysal Tan, F1
Koc, RS1
Erkek Ozturk Durmaz, E1
Tuncez Akyurek, F1
Korem, S1
Gandhi, H1
Dayag, DB1
Robakis, TK1
Redon, S1
Graillon, N1
Régis, J1
Donnet, A1
Wu, MY1
Liu, RF1
Chang, YY1
Nagandla, K1
De, S1
Thornsberry, LA1
English, JC1
Shinde, SS1
Seisler, D1
Soori, G1
Atherton, PJ1
Pachman, DR1
Lafky, J1
Ruddy, KJ1
Loprinzi, CL1
Hoeijmakers, JG1
Faber, CG1
Miedema, CJ1
Merkies, IS1
Vles, JS1
Garza, I1
Sharp, H1
Morris, JC1
Van Waes, C1
Gius, D1
Cooley-Zgela, T1
Singh, AK1
Biyik, I1
Gülcüler, M1
Karabiga, M1
Ergene, O1
Tayyar, N1
Ong, OL1
Churchyard, AC1
New, PW1
Tan, IL1
Polydefkis, MJ1
Ebenezer, GJ1
Hauer, P1
McArthur, JC1
Gerlinger, I1
Vogel, LC1
Anderson, CJ1
Lotery, HE1
McClure, N1
Galask, RP1
Wepner, U1
Zhang, C1
Glenn, DG1
Bell, WL1
O'Donovan, CA1
Sihoe, AD1
Lee, TW1
Wan, IY1
Thung, KH1
Yim, AP1
Mellick, GA1
Mellick, LB1
Pandey, CK1
Patra, P1
Pant, KC1
Singh, PK1
Celebi, N1
Sahin, A1
Canbay, O1
Uzümcügil, F1
Aypar, U1
Loosemore, MP1
Bordeaux, JS1
Bernhard, JD1
Otley, CC1
Dallocchio, C1
Buffa, C1
Mazzarello, P1
Chiroli, S1
Trinka, E1
Niedermüller, U1
Thaler, C1
Doering, S1
Moroder, T1
Ladurner, G1
Bauer, G1
Chow, GC1
Clarke, JT1
Banwell, BL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Phase I Dose Escalation Study Of The EGFR Tyrosine Kinase Inhibitor Gefitinib (Iressa) Combined With Paclitaxel (Taxol) And External Beam Radiation Therapy In Patients With Advanced Squamous Cell Carcinoma Of The Head And Neck (SCCHN)[NCT00083057]Phase 130 participants (Anticipated)Interventional2004-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gabapentin and Dysesthesia

ArticleYear
Restless legs syndrome: pathophysiology and modern management.
    Postgraduate medical journal, 2013, Volume: 89, Issue:1053

    Topics: Amines; Anemia; Anticonvulsants; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dopamine Agon

2013
[Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice].
    Ideggyogyaszati szemle, 2012, Sep-30, Volume: 65, Issue:9-10

    Topics: Acetamides; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Burning Mouth Syndrome

2012

Trials

5 trials available for gabapentin and Dysesthesia

ArticleYear
Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:2

    Topics: Acute Pain; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric

2016
High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers.
    American journal of clinical oncology, 2008, Volume: 31, Issue:6

    Topics: Adult; Aged; Amines; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squ

2008
Efficacy of gabapentin versus diclofenac in the treatment of chest pain and paresthesia in patients with sternotomy.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2009, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chest P

2009
The use of gabapentin for post-operative and post-traumatic pain in thoracic surgery patients.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 29, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin;

2006
Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study.
    Journal of pain and symptom management, 2000, Volume: 20, Issue:4

    Topics: Acetates; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Ataxia; Cyclohexanecarboxylic

2000

Other Studies

22 other studies available for gabapentin and Dysesthesia

ArticleYear
Circadian rhythmicity on red ear syndrome in a patient with migraine: A case report.
    Headache, 2021, Volume: 61, Issue:10

    Topics: Adult; Circadian Rhythm; Ear; Erythema; Female; Gabapentin; Humans; Migraine Disorders; Pain; Parest

2021
Gabapentin treatment in notalgia paresthetica: a preliminary report.
    International journal of dermatology, 2020, Volume: 59, Issue:4

    Topics: Adult; Back; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; Hum

2020
Guillain-Barré syndrome associated with COVID-19 disease.
    BMJ case reports, 2020, Sep-21, Volume: 13, Issue:9

    Topics: Analgesics; Betacoronavirus; Brain; Coronavirus Infections; COVID-19; Diagnosis, Differential; Femal

2020
Trypophobia Associated With Gabapentin: A Case Report.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:2

    Topics: Aged; Excitatory Amino Acid Antagonists; Female; Gabapentin; Humans; Paresthesia; Pattern Recognitio

2018
First Bite Syndrome After Trigeminal Radiosurgery: Case Report and Pathophysiology.
    Headache, 2018, Volume: 58, Issue:10

    Topics: Adult; Carbamazepine; Cheek; Combined Modality Therapy; Drug Therapy, Combination; Facial Muscles; F

2018
Image Gallery: Trigeminal trophic syndrome: nonhealing facial ulcer with corneal ulceration.
    The British journal of dermatology, 2019, Volume: 181, Issue:1

    Topics: Analgesics; Brain Infarction; Corneal Diseases; Facial Dermatoses; Female; Gabapentin; Humans; Medul

2019
Scalp dysesthesia related to cervical spine disease.
    JAMA dermatology, 2013, Volume: 149, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cervical Vertebrae; Cyclohexanecarboxylic Acids;

2013
Small Fiber Neuropathy in Children: Two Case Reports Illustrating the Importance of Recognition.
    Pediatrics, 2016, Volume: 138, Issue:4

    Topics: Adolescent; Amines; Analgesics; Biopsy; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Eryth

2016
The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Child; Cyclohexanecarboxylic Acids; Erythema; Fa

2008
The importance of early diagnosis of herpes zoster myelitis.
    The Medical journal of Australia, 2010, Nov-01, Volume: 193, Issue:9

    Topics: Acyclovir; Aged; Amines; Analgesics; Anti-Inflammatory Agents; Antiviral Agents; Cyclohexanecarboxyl

2010
Peripheral nerve toxic effects of nitrofurantoin.
    Archives of neurology, 2012, Volume: 69, Issue:2

    Topics: Amines; Analgesics; Anti-Infective Agents, Urinary; Biopsy; Cyclohexanecarboxylic Acids; Cystitis, I

2012
Self-injurious behavior in children and adolescents with spinal cord injuries.
    Spinal cord, 2002, Volume: 40, Issue:12

    Topics: Acetates; Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Fe

2002
Vulvodynia.
    Lancet (London, England), 2004, Mar-27, Volume: 363, Issue:9414

    Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Chroni

2004
[Evidence-based management of diabetic polyneuropathy. "Burning feet" alarm signal].
    MMW Fortschritte der Medizin, 2004, Jul-08, Volume: 146, Issue:27-28

    Topics: Amines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diabetic Foot; Diabetic Neuropathies

2004
Gabapentin-induced myoclonus in end-stage renal disease.
    Epilepsia, 2005, Volume: 46, Issue:1

    Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric

2005
Clinical presentation, quantitative sensory testing, and therapy of 2 patients with fourth thoracic syndrome.
    Journal of manipulative and physiological therapeutics, 2006, Volume: 29, Issue:5

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin for the treatment of refractory dysesthetic pain after open cholecystectomy.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:1

    Topics: Amines; Analgesics; Cholecystectomy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci

2006
Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:10

    Topics: Abdominal Pain; Adolescent; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Ele

2006
Gabapentin treatment for notalgia paresthetica, a common isolated peripheral sensory neuropathy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:10

    Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric A

2007
Gabapentin for the treatment of dysesthetic pain after reconstructive surgery.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1999, Volume: 25, Issue:6

    Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobuty

1999
Gabapentin-induced mood changes with hypomanic features in adults.
    Seizure, 2000, Volume: 9, Issue:7

    Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Chlamydia Infections; Cyclohexanecarboxylic Acids;

2000
Late-onset GM2 gangliosidosis presenting as burning dysesthesias.
    Pediatric neurology, 2001, Volume: 25, Issue:1

    Topics: Acetates; Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexa

2001