Page last updated: 2024-10-27

gabapentin and Disease Exacerbation

gabapentin has been researched along with Disease Exacerbation in 20 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"Using US health care utilization data, a large population-based cohort study was conducted to describe clinical characteristics and medication use patterns in patients diagnosed with fibromyalgia who newly started amitriptyline, duloxetine, gabapentin, or pregabalin."7.79Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin. ( Kim, SC; Landon, JE; Solomon, DH, 2013)
"Gabapentin is a modulator of the glutamatergic system and has been shown to prolong survival in the transgenic model of familial ALS."6.69The natural history and the effects of gabapentin in amyotrophic lateral sclerosis. ( Balzarini, C; Brigatti, M; Comazzi, F; Mazzini, L; Mora, G; Pastore, E; Pirali, I, 1998)
"Using US health care utilization data, a large population-based cohort study was conducted to describe clinical characteristics and medication use patterns in patients diagnosed with fibromyalgia who newly started amitriptyline, duloxetine, gabapentin, or pregabalin."3.79Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin. ( Kim, SC; Landon, JE; Solomon, DH, 2013)
"To examine the in vivo effects of PD-0200347, an alpha(2)delta ligand of voltage-activated Ca(2+) channels and a compound chemically related to pregabalin and gabapentin, on the development of cartilage structural changes in an experimental dog model of osteoarthritis (OA)."3.73Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes. ( Boileau, C; Boily, M; Brunet, J; El-Kattan, A; Flory, C; Martel-Pelletier, J; Pelletier, JP; Schrier, D; Tardif, G, 2005)
"Gabapentin is a modulator of the glutamatergic system and has been shown to prolong survival in the transgenic model of familial ALS."2.69The natural history and the effects of gabapentin in amyotrophic lateral sclerosis. ( Balzarini, C; Brigatti, M; Comazzi, F; Mazzini, L; Mora, G; Pastore, E; Pirali, I, 1998)
"The Dunning rat model of prostate cancer was used."1.43Gabapentin, an Analgesic Used Against Cancer-Associated Neuropathic Pain: Effects on Prostate Cancer Progression in an In Vivo Rat Model. ( Altun, S; Bugan, I; Djamgoz, MB; Karagoz, Z, 2016)
" It may be related with using a similar dosage of dopaminergic drugs."1.42Augmentation in restless legs syndrome patients in Korea. ( Cho, YW; Jeon, JY; Lee, HB; Moon, HJ; Song, ML, 2015)
"Early treatment of epilepsy is warranted to avoid possible severe consequences."1.39Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013)
"Delirium is still one of the most common and distressing symptoms in palliative care patients."1.38Reversible delirium in an advanced cancer patient. ( Jagsch, C; Kierner, KA; Watzke, HH, 2012)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's4 (20.00)29.6817
2010's11 (55.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Brito, BE1
García, MA1
De Gouveia, YM1
Bolaños, P1
Devis, S1
Bernal, G1
Tortorici-Brito, VA1
Baute, L1
Díaz-Serrano, G1
Tortorici, V1
Krishna, S1
Choudhury, A1
Keough, MB1
Seo, K1
Ni, L1
Kakaizada, S1
Lee, A1
Aabedi, A1
Popova, G1
Lipkin, B1
Cao, C1
Nava Gonzales, C1
Sudharshan, R1
Egladyous, A1
Almeida, N1
Zhang, Y1
Molinaro, AM1
Venkatesh, HS1
Daniel, AGS1
Shamardani, K1
Hyer, J1
Chang, EF1
Findlay, A1
Phillips, JJ1
Nagarajan, S1
Raleigh, DR1
Brang, D1
Monje, M1
Hervey-Jumper, SL1
Regan, DW1
Kashiwagi, D1
Dougan, B1
Sundsted, K1
Mauck, K1
Rapinesi, C1
Del Casale, A1
Serata, D1
Kotzalidis, GD1
Scatena, P1
Muzi, A1
Lazanio, S1
Savoja, V1
Carbonetti, P1
Fensore, C1
Ferracuti, S1
Angeletti, G1
Tatarelli, R1
Girardi, P1
Kim, SC1
Landon, JE1
Solomon, DH1
Jeon, JY1
Moon, HJ1
Song, ML1
Lee, HB1
Cho, YW1
Bugan, I1
Karagoz, Z1
Altun, S1
Djamgoz, MB1
Ward, RE1
Veerula, VL1
Ezra, N1
Travers, JB1
Mousdicas, N1
Matagne, V1
Ehinger, Y1
Saidi, L1
Borges-Correia, A1
Barkats, M1
Bartoli, M1
Villard, L1
Roux, JC1
Wolfe, KC1
Poma, R1
Kierner, KA1
Jagsch, C1
Watzke, HH1
Wadman, RI1
Bosboom, WM1
van der Pol, WL1
van den Berg, LH1
Wokke, JH1
Iannaccone, ST1
Vrancken, AF1
Gilron, I1
Bailey, JM1
Vandenkerkhof, EG1
Armon, C1
Wepner, U1
Boileau, C1
Martel-Pelletier, J1
Brunet, J1
Tardif, G1
Schrier, D1
Flory, C1
El-Kattan, A1
Boily, M1
Pelletier, JP1
Horvath, J1
Coeytaux, A1
Jallon, P1
Landis, T1
Temperli, P1
Burkhard, PR1
Galluzzi, KE1
Gurney, ME1
Cutting, FB1
Zhai, P1
Doble, A1
Taylor, CP1
Andrus, PK1
Hall, ED1
Mazzini, L1
Mora, G1
Balzarini, C1
Brigatti, M1
Pirali, I1
Comazzi, F1
Pastore, E1

Reviews

4 reviews available for gabapentin and Disease Exacerbation

ArticleYear
Update in perioperative medicine: practice changing evidence published in 2016.
    Hospital practice (1995), 2017, Volume: 45, Issue:4

    Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion;

2017
Drug treatment for spinal muscular atrophy types II and III.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: Acetylcarnitine; Adolescent; Amines; Child; Child, Preschool; Creatine; Cyclohexanecarboxylic Acids;

2012
How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 1999, Volume: 1, Issue:1

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohex

1999
Managing neuropathic pain.
    The Journal of the American Osteopathic Association, 2007, Volume: 107, Issue:10 Suppl 6

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Calcium Channel Blockers; Combined Modality Therapy; Cy

2007

Trials

1 trial available for gabapentin and Disease Exacerbation

ArticleYear
The natural history and the effects of gabapentin in amyotrophic lateral sclerosis.
    Journal of the neurological sciences, 1998, Volume: 160 Suppl 1

    Topics: Acetates; Administration, Oral; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarbo

1998

Other Studies

15 other studies available for gabapentin and Disease Exacerbation

ArticleYear
Concomitant Antihyperalgesic and Antitumor Effects of Gabapentin in a Murine Cancer Pain Model.
    International journal of molecular sciences, 2021, Sep-07, Volume: 22, Issue:18

    Topics: Analgesics; Animals; Antineoplastic Agents; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; D

2021
Glioblastoma remodelling of human neural circuits decreases survival.
    Nature, 2023, Volume: 617, Issue:7961

    Topics: Biopsy; Brain; Brain Neoplasms; Cell Proliferation; Cognition; Disease Progression; Gabapentin; Glio

2023
Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle.
    Brain injury, 2013, Volume: 27, Issue:7-8

    Topics: Accidents, Traffic; Aggression; Amines; Anterior Temporal Lobectomy; Anticonvulsants; Brain Injuries

2013
Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.
    Arthritis care & research, 2013, Volume: 65, Issue:11

    Topics: Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic

2013
Augmentation in restless legs syndrome patients in Korea.
    Sleep & breathing = Schlaf & Atmung, 2015, Volume: 19, Issue:2

    Topics: Aged; Aged, 80 and over; Amines; Benzothiazoles; Cross-Sectional Studies; Cyclohexanecarboxylic Acid

2015
Gabapentin, an Analgesic Used Against Cancer-Associated Neuropathic Pain: Effects on Prostate Cancer Progression in an In Vivo Rat Model.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:3

    Topics: Amines; Analgesics; Animals; Carcinogenesis; Cells, Cultured; Cyclohexanecarboxylic Acids; Disease M

2016
Multilevel symmetric neuropathic pruritus (MSNP) presenting as recalcitrant "generalized" pruritus.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:4

    Topics: Age Distribution; Aged; Amines; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Diseas

2016
A codon-optimized Mecp2 transgene corrects breathing deficits and improves survival in a mouse model of Rett syndrome.
    Neurobiology of disease, 2017, Volume: 99

    Topics: Amines; Animals; Apnea; Codon; Cyclohexanecarboxylic Acids; Dependovirus; Disease Models, Animal; Di

2017
Syringomyelia in the Cavalier King Charles spaniel (CKCS) dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2010, Volume: 51, Issue:1

    Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Arnold-Chiari Malformation; Breeding; Cyclohe

2010
Reversible delirium in an advanced cancer patient.
    Wiener medizinische Wochenschrift (1946), 2012, Volume: 162, Issue:1-2

    Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, No

2012
Chronobiological characteristics of neuropathic pain: clinical predictors of diurnal pain rhythmicity.
    The Clinical journal of pain, 2013, Volume: 29, Issue:9

    Topics: Amines; Analgesics; Analysis of Variance; Circadian Rhythm; Cyclohexanecarboxylic Acids; Diabetic Ne

2013
[Evidence-based management of diabetic polyneuropathy. "Burning feet" alarm signal].
    MMW Fortschritte der Medizin, 2004, Jul-08, Volume: 146, Issue:27-28

    Topics: Amines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diabetic Foot; Diabetic Neuropathies

2004
Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:2

    Topics: Administration, Oral; Amines; Animals; Cartilage, Articular; Chondrocytes; Cyclohexanecarboxylic Aci

2005
Carbamazepine encephalopathy masquerading as Creutzfeldt-Jakob disease.
    Neurology, 2005, Aug-23, Volume: 65, Issue:4

    Topics: Aged; Amines; Analgesics, Non-Narcotic; Atrophy; Basal Ganglia; Brain; Brain Damage, Chronic; Carbam

2005
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
    Annals of neurology, 1996, Volume: 39, Issue:2

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyclohexanecarboxylic Acids; Diet;

1996