Page last updated: 2024-10-27

gabapentin and Diffuse Myofascial Pain Syndrome

gabapentin has been researched along with Diffuse Myofascial Pain Syndrome in 35 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"This pilot study suggests that OMM treatment and gabapentin are safe and clinically efficacious treatment of pain and other constitutional and somatic symptoms associated with fibromyalgia."9.27Fibromyalgia with Gabapentin and Osteopathic Manipulative Medicine: A Pilot Study. ( Bernard, N; Bhattacharya, S; Brown, M; Klapstein, G; Marske, C; Palacios, A; Preiss, B; Wheeler, C, 2018)
"To assess the efficacy and safety of gabapentin in patients with fibromyalgia."9.12Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. ( Arnold, LM; Bishop, F; Goldenberg, DL; Hess, EV; Hudson, JI; Keck, PE; Lalonde, JK; Sandhu, HS; Stanford, KE; Stanford, SB; Welge, JA, 2007)
"This review replaces part of an earlier review that evaluated gabapentin for both neuropathic pain and fibromyalgia, now split into separate reviews for the two conditions."8.95Gabapentin for fibromyalgia pain in adults. ( Cooper, TE; Derry, S; Moore, RA; Wiffen, PJ, 2017)
"To assess the analgesic efficacy and adverse effects of gabapentin in chronic neuropathic pain and fibromyalgia."8.90Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Moore, RA; Rice, AS; Toelle, T; Wiffen, PJ, 2014)
"Twenty-nine studies (3571 participants), studied gabapentin at daily doses of 1200 mg or more in 12 chronic pain conditions; 78% of participants were in studies of postherpetic neuralgia, painful diabetic neuropathy or mixed neuropathic pain."8.87Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; McQuay, HJ; Moore, RA; Wiffen, PJ, 2011)
"The efficacy of gabapentin (GPT) and pregabalin (PGB) in the treatment of fibromyalgia syndrome (FMS) was assessed."8.85Treatment of fibromyalgia syndrome with gabapentin and pregabalin--a meta-analysis of randomized controlled trials. ( Bernardy, K; Häuser, W; Sommer, C; Uçeyler, N, 2009)
"We assessed the efficacy and safety of extended-release gabapentin in a 15-week, open-label, single-arm, single-center study in patients with fibromyalgia (FM)."7.83The Effect of a Novel form of Extended-Release Gabapentin on Pain and Sleep in Fibromyalgia Subjects: An Open-Label Pilot Study. ( Hong, KS; North, JM; Rauck, RL, 2016)
"Fibromyalgia patients had high health care utilization before and after initiation of amitriptyline, duloxetine, gabapentin, or pregabalin."7.81Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia. ( Kim, SC; Landon, JE; Lee, YC, 2015)
"Using US health care utilization data, a large population-based cohort study was conducted to describe clinical characteristics and medication use patterns in patients diagnosed with fibromyalgia who newly started amitriptyline, duloxetine, gabapentin, or pregabalin."7.79Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin. ( Kim, SC; Landon, JE; Solomon, DH, 2013)
"This model found pregabalin 300 mg and 450 mg to be cost effective compared with placebo and, within the limits of available evidence, against duloxetine using standard UK criteria in patients with fibromyalgia experiencing severe pain."7.76Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective. ( Bowrin, K; Choy, E; Lloyd, A; Richards, S; Sadosky, A; Watson, P; Zlateva, G, 2010)
"The aim of the present study was to determine the brain areas associated with fibromyalgia, and whether pretreatment regional cerebral blood flow (rCBF) can predict response to gabapentin treatment."7.76Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin. ( Arai, H; Doi, N; Hatta, K; Nakamura, H; Nakanishi, A; Nishioka, K; Usui, C, 2010)
"This pilot study suggests that OMM treatment and gabapentin are safe and clinically efficacious treatment of pain and other constitutional and somatic symptoms associated with fibromyalgia."5.27Fibromyalgia with Gabapentin and Osteopathic Manipulative Medicine: A Pilot Study. ( Bernard, N; Bhattacharya, S; Brown, M; Klapstein, G; Marske, C; Palacios, A; Preiss, B; Wheeler, C, 2018)
"To assess the efficacy and safety of gabapentin in patients with fibromyalgia."5.12Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. ( Arnold, LM; Bishop, F; Goldenberg, DL; Hess, EV; Hudson, JI; Keck, PE; Lalonde, JK; Sandhu, HS; Stanford, KE; Stanford, SB; Welge, JA, 2007)
"The gabapentinoid drugs gabapentin and pregabalin were originally developed as antiseizure drugs but now are prescribed mainly for treatment of pain."5.01A Clinical Overview of Off-label Use of Gabapentinoid Drugs. ( Brett, AS; Goodman, CW, 2019)
"Gabapentin at doses of 1800 mg to 3600 mg daily (1200 mg to 3600 mg gabapentin encarbil) can provide good levels of pain relief to some people with postherpetic neuralgia and peripheral diabetic neuropathy."4.95Gabapentin for chronic neuropathic pain in adults. ( Bell, RF; Derry, S; Moore, RA; Phillips, T; Rice, AS; Tölle, TR; Wiffen, PJ, 2017)
"We know from adult randomised controlled trials that some antiepileptics, such as gabapentin and pregabalin, can be effective in certain chronic pain conditions."4.95Antiepileptic drugs for chronic non-cancer pain in children and adolescents. ( Clinch, J; Cooper, TE; Heathcote, LC; Howard, R; Krane, E; Lord, SM; Schechter, N; Sethna, N; Wiffen, PJ; Wood, C, 2017)
"This review replaces part of an earlier review that evaluated gabapentin for both neuropathic pain and fibromyalgia, now split into separate reviews for the two conditions."4.95Gabapentin for fibromyalgia pain in adults. ( Cooper, TE; Derry, S; Moore, RA; Wiffen, PJ, 2017)
"With anticonvulsant, anxiolytic, and analgesic properties, pregabalin has been evaluated for neuropathic pain and fibromyalgia (FM)."4.91A systematic review of pharmacoeconomic studies for pregabalin. ( Huelin, R; Khankhel, Z; Mould, J; Parker, L; Wasiak, R, 2015)
"To assess the analgesic efficacy and adverse effects of gabapentin in chronic neuropathic pain and fibromyalgia."4.90Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Moore, RA; Rice, AS; Toelle, T; Wiffen, PJ, 2014)
"For gabapentin and pregabalin only we found reasonably good second tier evidence for efficacy in painful diabetic neuropathy and postherpetic neuralgia."4.89Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews. ( Aldington, D; Cole, P; Derry, S; Haanpaa, M; Hamunen, K; Kalso, EA; Lunn, MP; Moore, RA; Rice, AS; Wiffen, PJ, 2013)
"This systematic review evaluates the benefits and harms of using the antiepileptic drugs gabapentin and pregabalin for the treatment of fibromyalgia."4.87Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia. ( Cushman, T; Gardner, H; McDonagh, M; Siler, AC; Yanit, K, 2011)
"Twenty-nine studies (3571 participants), studied gabapentin at daily doses of 1200 mg or more in 12 chronic pain conditions; 78% of participants were in studies of postherpetic neuralgia, painful diabetic neuropathy or mixed neuropathic pain."4.87Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; McQuay, HJ; Moore, RA; Wiffen, PJ, 2011)
"The efficacy of gabapentin (GPT) and pregabalin (PGB) in the treatment of fibromyalgia syndrome (FMS) was assessed."4.85Treatment of fibromyalgia syndrome with gabapentin and pregabalin--a meta-analysis of randomized controlled trials. ( Bernardy, K; Häuser, W; Sommer, C; Uçeyler, N, 2009)
"We assessed the efficacy and safety of extended-release gabapentin in a 15-week, open-label, single-arm, single-center study in patients with fibromyalgia (FM)."3.83The Effect of a Novel form of Extended-Release Gabapentin on Pain and Sleep in Fibromyalgia Subjects: An Open-Label Pilot Study. ( Hong, KS; North, JM; Rauck, RL, 2016)
"Fibromyalgia patients had high health care utilization before and after initiation of amitriptyline, duloxetine, gabapentin, or pregabalin."3.81Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia. ( Kim, SC; Landon, JE; Lee, YC, 2015)
"Using US health care utilization data, a large population-based cohort study was conducted to describe clinical characteristics and medication use patterns in patients diagnosed with fibromyalgia who newly started amitriptyline, duloxetine, gabapentin, or pregabalin."3.79Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin. ( Kim, SC; Landon, JE; Solomon, DH, 2013)
"This model found pregabalin 300 mg and 450 mg to be cost effective compared with placebo and, within the limits of available evidence, against duloxetine using standard UK criteria in patients with fibromyalgia experiencing severe pain."3.76Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective. ( Bowrin, K; Choy, E; Lloyd, A; Richards, S; Sadosky, A; Watson, P; Zlateva, G, 2010)
"The aim of the present study was to determine the brain areas associated with fibromyalgia, and whether pretreatment regional cerebral blood flow (rCBF) can predict response to gabapentin treatment."3.76Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin. ( Arai, H; Doi, N; Hatta, K; Nakamura, H; Nakanishi, A; Nishioka, K; Usui, C, 2010)
"The data from the fibromyalgia impact questionnaire (FIQ) and the physical and mental subscales short form 36 (SF36) were extracted at last follow-up."2.82Pharmacological management of fibromyalgia: a Bayesian network meta-analysis. ( Colarossi, G; Eschweiler, J; Knobe, M; Maffulli, N; Migliorini, F; Tingart, M, 2022)
"Anxiety and depression are often also present."1.35Fibromyalgia: poorly understood; treatments are disappointing. ( , 2009)
"Vgx rats showed sustained hyperalgesia in the gastrocnemius muscle without tissue damage (no increase in vgx-induced plasma creatine phosphokinase or lactose dehydrogenase levels) accompanied by hypersensitivity to colonic distension."1.35Subdiaphragmatic vagotomy promotes nociceptive sensitivity of deep tissue in rats. ( Furuta, S; Horie, S; Kuzumaki, N; Matsumoto, K; Narita, M; Shimizu, T; Suzuki, T, 2009)
"The surgical treatment of cervical myelopathy due to spinal cord or caudal brainstem compression in patients carrying the diagnosis of fibromyalgia can result in a significant improvement in a wide array of symptoms usually attributed to fibromyalgia with attendant measurable improvements in the quality of life."1.34Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications. ( Elias, DA; Heffez, DS; Kostas, K; Morrissey, M; Ross, RE; Shade-Zeldow, Y; Shepard, A, 2007)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (31.43)29.6817
2010's20 (57.14)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
Migliorini, F1
Maffulli, N1
Eschweiler, J1
Knobe, M1
Tingart, M1
Colarossi, G1
Merante, D1
Dhokia, M1
Elander, J1
Clements, K1
Gilbert, P1
Mathieson, S1
Lin, CC1
Underwood, M1
Eldabe, S1
Wiffen, PJ6
Derry, S5
Bell, RF1
Rice, AS3
Tölle, TR1
Phillips, T1
Moore, RA5
Cooper, TE2
Heathcote, LC1
Clinch, J1
Howard, R1
Krane, E1
Lord, SM1
Sethna, N1
Schechter, N1
Wood, C1
Üçeyler, N3
Sommer, C3
Walitt, B2
Häuser, W3
Marske, C1
Bernard, N1
Palacios, A1
Wheeler, C1
Preiss, B1
Brown, M1
Bhattacharya, S1
Klapstein, G1
King, HH1
Goodman, CW1
Brett, AS1
Kim, SC2
Landon, JE2
Solomon, DH1
Aldington, D1
Cole, P1
Lunn, MP1
Hamunen, K1
Haanpaa, M1
Kalso, EA1
Toelle, T1
Parker, L1
Huelin, R1
Khankhel, Z1
Wasiak, R1
Mould, J1
Montserrat-de la Paz, S1
García-Giménez, MD1
Ángel-Martín, M1
Fernández-Arche, A1
Lee, YC1
North, JM1
Hong, KS1
Rauck, RL1
Abeles, M1
Solitar, BM1
Pillinger, MH1
Abeles, AM1
Bannwarth, B1
Nishiyori, M1
Ueda, H1
Bernardy, K1
Peres, MF1
Furuta, S1
Shimizu, T1
Narita, M2
Matsumoto, K1
Kuzumaki, N1
Horie, S1
Suzuki, T1
Choy, E1
Richards, S1
Bowrin, K1
Watson, P1
Lloyd, A1
Sadosky, A1
Zlateva, G1
Usui, C1
Hatta, K1
Doi, N1
Nakanishi, A1
Nakamura, H1
Nishioka, K1
Arai, H1
Tzellos, TG1
Toulis, KA1
Goulis, DG1
Papazisis, G1
Zampeli, VA1
Vakfari, A1
Kouvelas, D1
Siler, AC1
Gardner, H1
Yanit, K1
Cushman, T1
McDonagh, M1
McQuay, HJ1
Arnold, LM1
Goldenberg, DL2
Stanford, SB1
Lalonde, JK1
Sandhu, HS1
Keck, PE1
Welge, JA1
Bishop, F1
Stanford, KE1
Hess, EV1
Hudson, JI1
Heffez, DS1
Ross, RE1
Shade-Zeldow, Y1
Kostas, K1
Morrissey, M1
Elias, DA1
Shepard, A1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887]Phase 4110 participants (Anticipated)Interventional2023-01-01Enrolling by invitation
GABA-WHY Study: Deprescription of Gabapentinoids in Medical Inpatients[NCT04855578]160 participants (Actual)Interventional2021-05-28Completed
Cannabidiol for Fibromyalgia -The CANNFIB Trial Protocol for a Randomized, Double-blind, Placebo-controlled, Parallel-group, Single-center Trial[NCT04729179]Phase 3200 participants (Anticipated)Interventional2021-03-01Recruiting
Fibromyalgia of Less Than One Year Duration in Primary Care: Treatment Response in a Double Blind, Placebo Controlled Study of Pregabalin[NCT01397006]Phase 40 participants (Actual)Interventional2011-09-30Withdrawn
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis[NCT05603702]Phase 124 participants (Anticipated)Interventional2023-03-17Recruiting
Open Labeled, Non-randomized, Study of Efficacy and Safety of Gralise in Fibromyalgia Patients.[NCT02052414]34 participants (Actual)Interventional2012-07-31Completed
Phase III Study of the Use of Gabapentin and Osteopathic Manipulative Medicine to Treat Fibromyalgia[NCT01107574]Phase 341 participants (Actual)Interventional2004-04-30Completed
Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313]152 participants (Actual)Interventional2015-03-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Fibromyalgia Impact Questionnaire (FIQ)

The Fibromyalgia Impact Questionnaire (FIQ) is an instrument designed to quantitate the overall impact of fibromyalgia over many dimensions (e.g. function, pain level, fatigue, sleep disturbance, psychological distress etc.). It is scored from 0 to 100 with the latter number being the worst case. The average score for patients seen in tertiary care settings is about 50. The FIQ is widely used to assess change in fibromyalgia status. (NCT02052414)
Timeframe: 15 weeks.

Interventionunits on a scale (Mean)
FIQ BaselineFIQ Week 4FIQ Week 8FIQ Week 12FIQ Week 15
Gralise (Gabapentin ER)71.0441.8240.7939.2761.86

Medical Outcome Study (MOS) Sleep Questionnaires

"Medical Outcomes Study (MOS) sleep questionnaires to assess how Fibromyalgia impacts patients' sleep in various areas.~Specifically, Data reported below measured number of hours subjects spent per night sleeping. MOS sleep questionnaires were assessed at each follow up visits. (visits 1, 2, 3, 4, and 5)." (NCT02052414)
Timeframe: 15 weeks

InterventionHours (Mean)
Sleep Quantity BaselineSleep Quantity week 4Sleep quantity week 8Sleep quantity week 12Sleep quantity week 15
Gralise (Gabapentin ER)5.867.176.817.046.23

Numeric Pain Rating System (NPRS)

Fibromyalgia pain experienced by study subjects will be captured using NPRS at baseline visit, at each follow visits that are scheduled to occur every 4 weeks over 12 weeks of treatment period, and at the end of treatment visit that will occur 3 weeks after treatment period (12 weeks treatment period + 3 weeks = 15 weeks). Any difference in NPRS scores between baseline and any subsequent visits will indicate the magnitude of pain relief as reflected in digital scale of 0-10 (0=no pain, 10=worst pain imaginable). (NCT02052414)
Timeframe: 15 weeks

Interventionunits on a scale (Mean)
NPRS Baseline (Visit 1)NPRS on Week 4 (Visit 2)NPRS on week 8 (Visit 3)NPRS on Week 12 (Visit 4)NPRS on week 15 (Visit 5)
Gralise (Gabapentin ER)7.294.723.953.836.94

Patient Global Impression of Change (PGIC)

Patient Global impression of Change (PGIC) is an outcome commonly used measure of the efficacy of treatments. PGIC is a 7 point scale that requires the subjects to assess how much the patient's illness has improved or worsened relative to a baseline state at the beginning of the intervention. and rated as: 1, very much improved; 2, much improved; 3, minimally improved; 4, no change; 5, minimally worse; 6, much worse; or 7, very much worse. (NCT02052414)
Timeframe: 15 Weeks.

Interventionunits on a scale (Mean)
PGIC After 4 weeksPGIC After 8 weeksPGIC After 12 weeksPGIC After 15 weeks
Gralise (Gabapentin ER)4.965.405.374.44

Self Reported Side Effects.

Side / adverse effects were assessed at each follow up visits and resulted are as follows. (NCT02052414)
Timeframe: 15 Weeks

Interventionparticipants (Number)
Extremity SwellingWeight GainDrowsyDizzyIrritabilityDry EyesPainMood ChangesDifficulty ConcentratingDry MouthSuspected Drug interactionAcute DeleriumAdhesionNone
Gralise (Gabapentin ER)228332122111112

Reviews

19 reviews available for gabapentin and Diffuse Myofascial Pain Syndrome

ArticleYear
Pharmacological management of fibromyalgia: a Bayesian network meta-analysis.
    Expert review of clinical pharmacology, 2022, Volume: 15, Issue:2

    Topics: Analgesics; Duloxetine Hydrochloride; Fibromyalgia; Gabapentin; Humans; Network Meta-Analysis; Prega

2022
The mirogabalin ALDAY phase 3 program in pain associated with fibromyalgia: the lessons learned.
    Current medical research and opinion, 2020, Volume: 36, Issue:4

    Topics: Bridged Bicyclo Compounds; Clinical Trials, Phase III as Topic; Double-Blind Method; Fibromyalgia; G

2020
Pregabalin and gabapentin for pain.
    BMJ (Clinical research ed.), 2020, Apr-28, Volume: 369

    Topics: Analgesics; Diabetic Neuropathies; Evidence-Based Medicine; Fibromyalgia; Gabapentin; Humans; Neural

2020
Gabapentin for chronic neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2017, 06-09, Volume: 6

    Topics: Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Diabetic Neur

2017
Antiepileptic drugs for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-05, Volume: 8

    Topics: Adolescent; Amines; Amitriptyline; Anticonvulsants; Child; Chronic Pain; Complex Regional Pain Syndr

2017
WITHDRAWN: Anticonvulsants for fibromyalgia.
    The Cochrane database of systematic reviews, 2017, 10-09, Volume: 10

    Topics: Acetamides; Amines; Anticonvulsants; Conflict of Interest; Cyclohexanecarboxylic Acids; Fibromyalgia

2017
A Clinical Overview of Off-label Use of Gabapentinoid Drugs.
    JAMA internal medicine, 2019, 05-01, Volume: 179, Issue:5

    Topics: Analgesics; Diabetic Neuropathies; Drug Approval; Fibromyalgia; Gabapentin; Humans; Low Back Pain; M

2019
Anticonvulsants for fibromyalgia.
    The Cochrane database of systematic reviews, 2013, Oct-16, Issue:10

    Topics: Acetamides; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Am

2013
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2013, Nov-11, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric A

2013
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2013, Nov-11, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric A

2013
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2013, Nov-11, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric A

2013
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2013, Nov-11, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric A

2013
Gabapentin for chronic neuropathic pain and fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2014, Apr-27, Issue:4

    Topics: Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Fibromyalgia;

2014
A systematic review of pharmacoeconomic studies for pregabalin.
    Pain practice : the official journal of World Institute of Pain, 2015, Volume: 15, Issue:1

    Topics: Amines; Analgesics; Anticonvulsants; Chronic Disease; Cost-Benefit Analysis; Cyclohexanecarboxylic A

2015
Gabapentin for fibromyalgia pain in adults.
    The Cochrane database of systematic reviews, 2017, 01-03, Volume: 1

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Fibromyalgia; Gabapentin; gamma-Amin

2017
Update on fibromyalgia therapy.
    The American journal of medicine, 2008, Volume: 121, Issue:7

    Topics: Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Complementa

2008
Treatment of fibromyalgia syndrome with gabapentin and pregabalin--a meta-analysis of randomized controlled trials.
    Pain, 2009, Volume: 145, Issue:1-2

    Topics: Amines; Analgesics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Databases, Bibliographic;

2009
Fibromyalgia and headache disorders.
    Current pain and headache reports, 2009, Volume: 13, Issue:5

    Topics: Amines; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Headache Dis

2009
Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fem

2010
Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia.
    The journal of pain, 2011, Volume: 12, Issue:4

    Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabape

2011
Gabapentin for chronic neuropathic pain and fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Am

2011
Pharmacological treatment of fibromyalgia and other chronic musculoskeletal pain.
    Best practice & research. Clinical rheumatology, 2007, Volume: 21, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tr

2007

Trials

3 trials available for gabapentin and Diffuse Myofascial Pain Syndrome

ArticleYear
A randomized-controlled pilot trial of an online compassionate mind training intervention to help people with chronic pain avoid analgesic misuse.
    Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2020, Volume: 34, Issue:7

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Arthritis, Rheumatoid; Aspirin; Back Pain; Chr

2020
Fibromyalgia with Gabapentin and Osteopathic Manipulative Medicine: A Pilot Study.
    Journal of alternative and complementary medicine (New York, N.Y.), 2018, Volume: 24, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyri

2018
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Meth

2007

Other Studies

13 other studies available for gabapentin and Diffuse Myofascial Pain Syndrome

ArticleYear
Fibromyalgia Symptoms Reduced by Osteopathic Manipulative Medicine and Gabapentin.
    The Journal of the American Osteopathic Association, 2018, 05-01, Volume: 118, Issue:5

    Topics: Fibromyalgia; Gabapentin; Humans; Manipulation, Osteopathic; Osteopathic Medicine; Pilot Projects

2018
Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.
    Arthritis care & research, 2013, Volume: 65, Issue:11

    Topics: Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic

2013
Validation and additional support for an experimental animal model of fibromyalgia.
    Modern rheumatology, 2015, Volume: 25, Issue:1

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Female; Fibromya

2015
Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.
    Arthritis research & therapy, 2015, Jan-28, Volume: 17

    Topics: Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Cohort Studies; Cyclohexanecarboxylic Acids;

2015
The Effect of a Novel form of Extended-Release Gabapentin on Pain and Sleep in Fibromyalgia Subjects: An Open-Label Pilot Study.
    Pain practice : the official journal of World Institute of Pain, 2016, Volume: 16, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Prep

2016
Is there a role for anticonvulsants in the management of rheumatic pain?
    Joint bone spine, 2008, Volume: 75, Issue:6

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Am

2008
Prolonged gabapentin analgesia in an experimental mouse model of fibromyalgia.
    Molecular pain, 2008, Nov-06, Volume: 4

    Topics: Amines; Analgesia; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Ad

2008
Fibromyalgia: poorly understood; treatments are disappointing.
    Prescrire international, 2009, Volume: 18, Issue:102

    Topics: Acetaminophen; Acupuncture Therapy; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Ant

2009
Subdiaphragmatic vagotomy promotes nociceptive sensitivity of deep tissue in rats.
    Neuroscience, 2009, Dec-15, Volume: 164, Issue:3

    Topics: Amines; Amitriptyline; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Diaphragm; Disease

2009
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective.
    Current medical research and opinion, 2010, Volume: 26, Issue:4

    Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanec

2010
Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin.
    Arthritis research & therapy, 2010, Volume: 12, Issue:2

    Topics: Adult; Aged; Amines; Analgesics; Brain; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Cy

2010
Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2007, Volume: 16, Issue:9

    Topics: Adult; Amines; Analgesics; Case-Control Studies; Cervical Vertebrae; Cyclohexanecarboxylic Acids; De

2007
Fibromyalgia: understanding a mysterious ailment.
    The Johns Hopkins medical letter health after 50, 2007, Volume: 19, Issue:9

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid;

2007