Page last updated: 2024-10-27

gabapentin and Depressive Disorder

gabapentin has been researched along with Depressive Disorder in 13 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
"To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine."8.81Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002)
"To determine if gabapentin is effective either as adjunctive treatment or as monotherapy for major affective disorders in a naturalistic setting."7.70Gabapentin treatment of mood disorders: a preliminary study. ( Desai, SP; Ghaemi, SN; Goodwin, FK; Katzow, JJ, 1998)
"To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine."4.81Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002)
"A chart review was conducted on 27 outpatients presenting with a depressive disorder in whom gabapentin was added to ongoing treatment with a conventional antidepressant to which patients had not responded after at least 6 weeks."3.71Adjunctive gabapentin in treatment-resistant depression: a retrospective chart review. ( Carpenter, LL; Leon, Z; Price, LH; Siniscalchi, JM; Yasmin, S, 2001)
"To determine if gabapentin is effective in monotherapy or add-on treatment of non-refractory bipolar disorder in open prospective treatment."3.71Gabapentin treatment of the non-refractory bipolar spectrum: an open case series. ( Ghaemi, SN; Goodwin, FK, 2001)
"To determine if gabapentin is effective either as adjunctive treatment or as monotherapy for major affective disorders in a naturalistic setting."3.70Gabapentin treatment of mood disorders: a preliminary study. ( Desai, SP; Ghaemi, SN; Goodwin, FK; Katzow, JJ, 1998)
"Forty adult patients with partial epilepsy were studied in a prospective, non-randomized fashion with interviewer-rated and self-rated scales of mood and anxiety: the Cornell Dysthymia Rating Scale (CDRS), Beck Depression Inventory (BDI), and Hamilton Depression (Ham-D) and Anxiety (Ham-A) Scales."2.69A beneficial effect on mood in partial epilepsy patients treated with gabapentin. ( Carson, D; Goldstein, MA; Harden, CL; Kocsis, JH; Labar, DR; Lazar, LM; Nikolov, B; Pick, LH; Ravdin, LD, 1999)
"Cases with EoE with a psychiatric diagnosis were more likely to be women, white, and 18 years or older and to have a longer symptom duration before diagnosis."1.56Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation. ( Corder, SR; Dellon, ES; Eluri, S; Kim, E; Reed, CC; Sanders, E; Tappata, M, 2020)
"All patients had substance use disorders, the large majority (72 %) to more than one substance."1.43Abuse of Gabapentin is Associated with Opioid Addiction. ( Bastiaens, L; Galus, J; Mazur, C, 2016)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's6 (46.15)29.6817
2010's1 (7.69)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Reed, CC1
Corder, SR1
Kim, E1
Sanders, E1
Tappata, M1
Eluri, S1
Dellon, ES1
van den Driest, JJ1
Schiphof, D1
de Wilde, M1
Bindels, PJE1
van der Lei, J1
Bierma-Zeinstra, SMA1
Bastiaens, L1
Galus, J1
Mazur, C1
Yatham, LN1
Howland, RH1
Skolnick, AA1
Manack, L1
Ghaemi, SN2
Katzow, JJ1
Desai, SP1
Goodwin, FK2
Harden, CL1
Lazar, LM1
Pick, LH1
Nikolov, B1
Goldstein, MA1
Carson, D1
Ravdin, LD1
Kocsis, JH1
Labar, DR1
Maurer, I1
Volz, HP1
Sauer, H1
Yasmin, S1
Carpenter, LL1
Leon, Z1
Siniscalchi, JM1
Price, LH1
Robillard, M1
Conn, D1
Hurley, SC1

Reviews

3 reviews available for gabapentin and Depressive Disorder

ArticleYear
Newer anticonvulsants in the treatment of bipolar disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 10

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Dep

2004
Anticonvulsant drug therapies.
    Journal of psychosocial nursing and mental health services, 2005, Volume: 43, Issue:6

    Topics: Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Di

2005
Lamotrigine update and its use in mood disorders.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5

    Topics: Acetates; Aggression; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids;

2002

Trials

1 trial available for gabapentin and Depressive Disorder

ArticleYear
A beneficial effect on mood in partial epilepsy patients treated with gabapentin.
    Epilepsia, 1999, Volume: 40, Issue:8

    Topics: Acetates; Adult; Affect; Aged; Amines; Anticonvulsants; Anxiety Disorders; Comorbidity; Cyclohexanec

1999

Other Studies

9 other studies available for gabapentin and Depressive Disorder

ArticleYear
Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Anxiety Disorders; Benzodiazepines; Chest Pain; Child; Chronic

2020
Antidepressant and anticonvulsant prescription rates in patients with osteoarthritis: a population-based cohort study.
    Rheumatology (Oxford, England), 2021, 05-14, Volume: 60, Issue:5

    Topics: Aged; Analgesics; Anticonvulsants; Antidepressive Agents; Depressive Disorder; Drug Prescriptions; F

2021
Abuse of Gabapentin is Associated with Opioid Addiction.
    The Psychiatric quarterly, 2016, Volume: 87, Issue:4

    Topics: Adult; Amines; Attention Deficit Disorder with Hyperactivity; Comorbidity; Criminals; Cyclohexanecar

2016
Science reporters hear wide range of recent data at 12th annual conference.
    JAMA, 1993, Nov-24, Volume: 270, Issue:20

    Topics: Acetates; Aged; AIDS Vaccines; American Medical Association; Amines; Animals; Anticonvulsants; beta-

1993
Gabapentin treatment of mood disorders: a preliminary study.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:8

    Topics: Acetates; Adolescent; Adult; Aged; Ambulatory Care; Amines; Anticonvulsants; Antidepressive Agents;

1998
Gabapentin leads to remission of somatoform pain disorder with major depression.
    Pharmacopsychiatry, 1999, Volume: 32, Issue:6

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapen

1999
Adjunctive gabapentin in treatment-resistant depression: a retrospective chart review.
    Journal of affective disorders, 2001, Volume: 63, Issue:1-3

    Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Depressive Disorder; Dose

2001
Gabapentin treatment of the non-refractory bipolar spectrum: an open case series.
    Journal of affective disorders, 2001, Volume: 65, Issue:2

    Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive

2001
Gabapentin use in geriatric patients with depression and bipolar illness.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:8

    Topics: Acetates; Aged; Aged, 80 and over; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarbo

2001