Page last updated: 2024-10-27

gabapentin and Depressive Disorder, Major

gabapentin has been researched along with Depressive Disorder, Major in 5 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"Neuropathic pain is a chronic debilitating condition caused by injury or disease of the nerves of the somatosensory system."1.62Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain. ( Amato, A; Di Giorgio, FP; di Matteo, A; Durando, L; Garrone, B; Milanese, C; Pistillo, L; Tongiani, S, 2021)
"Gabapentin is an antiepileptic drug that is prescribed for both FDA-approved and multiple off-label conditions, and has a relatively safe side-effect profile."1.37Suicide by gabapentin overdose. ( Middleton, O, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Garrone, B1
di Matteo, A1
Amato, A1
Pistillo, L1
Durando, L1
Milanese, C1
Di Giorgio, FP1
Tongiani, S1
Mowla, A1
Ahmadzadeh, L1
Razeghian Jahromi, L1
Dastgheib, SA1
Bonnet, U1
Ossowski, A1
Schubert, M1
Gall, H1
Steinkamp, I1
Richter, LE1
Khalil-Boutros, Y1
Nefedev, A1
Kuhlmann, R1
Middleton, O1
Malek-Ahmadi, P1

Trials

1 trial available for gabapentin and Depressive Disorder, Major

ArticleYear
Comparing Gabapentin with Clonazepam for Residual Sleeping Problems following Antidepressant Therapy in Patients with Major Depressive Disorder: A Randomized Clinical Trial.
    Clinical drug investigation, 2015, Volume: 35, Issue:8

    Topics: Adult; Amines; Antidepressive Agents; Clonazepam; Cyclohexanecarboxylic Acids; Depressive Disorder,

2015

Other Studies

4 other studies available for gabapentin and Depressive Disorder, Major

ArticleYear
Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Analgesics; Animals; Anti-Anxiety Agents; Depressive Disorder, Major; Disease Models, Animal; Drug S

2021
[On the Differential Diagnosis of Intractable Psychogenic Chronic Cough: Neuropathic Larynx Irritable - Gabapentin's Antitussive Action].
    Fortschritte der Neurologie-Psychiatrie, 2015, Volume: 83, Issue:10

    Topics: Aged; Amines; Avitaminosis; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Depressive Disorder

2015
Suicide by gabapentin overdose.
    Journal of forensic sciences, 2011, Volume: 56, Issue:5

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Depressive Disorder, Major; Drug Overdose; Fem

2011
Gabapentin and posttraumatic stress disorder.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:5

    Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Cyclohexanec

2003