Page last updated: 2024-10-27

gabapentin and Demyelinating Diseases

gabapentin has been researched along with Demyelinating Diseases in 2 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Research Excerpts

ExcerptRelevanceReference
"Although mouse models of experimental autoimmune encephalomyelitis (EAE) have provided insight on the pathobiology of MS-induced neuropathic pain, concurrent severe motor impairments confound quantitative assessment of pain behaviors over the disease course."1.40Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. ( Khan, N; Smith, MT; Woodruff, TM, 2014)
"In ethidium bromide treated rats, gabapentin administered at 300 mg/kg increased cortical MDA by 66%."1.38The effect of gabapentin on oxidative stress in a model of toxic demyelination in rat brain. ( Abdel-Salam, OM; Khadrawy, YA; Mohammed, NA; Youness, ER, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khan, N1
Woodruff, TM1
Smith, MT1
Abdel-Salam, OM1
Khadrawy, YA1
Mohammed, NA1
Youness, ER1

Other Studies

2 other studies available for gabapentin and Demyelinating Diseases

ArticleYear
Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 126

    Topics: Amines; Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclohexanecarboxyli

2014
The effect of gabapentin on oxidative stress in a model of toxic demyelination in rat brain.
    Journal of basic and clinical physiology and pharmacology, 2012, Volume: 23, Issue:2

    Topics: Amines; Animals; Antioxidants; Cerebral Cortex; Cyclohexanecarboxylic Acids; Demyelinating Diseases;

2012