Page last updated: 2024-10-27

gabapentin and Delayed Effects, Prenatal Exposure

gabapentin has been researched along with Delayed Effects, Prenatal Exposure in 7 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" We examined the risk of major congenital malformations and cardiac defects associated with gabapentin exposure during the first trimester (T1), and the risk of preeclampsia (PE), preterm birth (PTB), small for gestational age (SGA), and neonatal intensive care unit admission (NICUa) associated with gabapentin exposure early, late, or both early and late in pregnancy."7.96Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. ( Bateman, BT; Cohen, JM; Desai, RJ; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Patorno, E, 2020)
" We examined the risk of major congenital malformations and cardiac defects associated with gabapentin exposure during the first trimester (T1), and the risk of preeclampsia (PE), preterm birth (PTB), small for gestational age (SGA), and neonatal intensive care unit admission (NICUa) associated with gabapentin exposure early, late, or both early and late in pregnancy."3.96Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. ( Bateman, BT; Cohen, JM; Desai, RJ; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Patorno, E, 2020)
" When medically indicated, limiting use of multiple psychiatric medications, particularly benzodiazepines and gabapentin, during pregnancy should be considered to improve NAS outcomes."3.88Impact of psychiatric medication co-exposure on Neonatal Abstinence Syndrome severity. ( Nikita, FNU; Saia, K; Schiff, DM; Shaw, D; Shrestha, H; Thomas, Z; Thomas-Lewis, JA; Wachman, EM; Warden, AH, 2018)
" It still remains unclear how much these drugs are safe during pregnancy."1.51The neurotoxic effects of prenatal gabapentin and oxcarbazepine exposure on newborn rats. ( Ayas, B; Ercument Beyhun, N; Erisgin, Z; Nyengaard, JR; Terzi, Y, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Loudin, S2
Haas, J2
Payne, M1
Linz, MF1
Meaney-Delman, D1
Honein, MA1
Saunders, A1
Maddox, TR1
Andrews, L1
Miller, B1
Davies, TH1
Patorno, E1
Hernandez-Diaz, S1
Huybrechts, KF1
Desai, RJ1
Cohen, JM1
Mogun, H1
Bateman, BT1
Erisgin, Z1
Ayas, B1
Nyengaard, JR1
Ercument Beyhun, N1
Terzi, Y1
Wachman, EM1
Warden, AH1
Thomas, Z1
Thomas-Lewis, JA1
Shrestha, H1
Nikita, FNU1
Shaw, D1
Saia, K1
Schiff, DM1
Murray, S1
Prunty, L1
Davies, T1
Evans, J1
Werthammer, J1
Czubak, A1
Nowakowska, E1
Kus, K1
Sadowski, C1
Matschay, A1

Other Studies

7 other studies available for gabapentin and Delayed Effects, Prenatal Exposure

ArticleYear
Identifying Co-Exposure to Opiates and Gabapentin During Pregnancy.
    The Journal of pediatrics, 2020, Volume: 217

    Topics: Analgesics, Opioid; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; Humans

2020
Abnormal Presentation of Hypoxic Ischemic Encephalopathy Attributed to Polysubstance Exposure.
    The American journal of case reports, 2019, Nov-20, Volume: 20

    Topics: Benzodiazepines; Buprenorphine; Female; Gabapentin; Heroin; Humans; Hypoxia-Ischemia, Brain; Infant,

2019
Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset.
    PLoS medicine, 2020, Volume: 17, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Cohort Studies; Female; Gabapentin; Humans; Infant, Small for Ge

2020
The neurotoxic effects of prenatal gabapentin and oxcarbazepine exposure on newborn rats.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019, Volume: 32, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Brain; Dopaminergic Neurons; Female; Gabapen

2019
Impact of psychiatric medication co-exposure on Neonatal Abstinence Syndrome severity.
    Drug and alcohol dependence, 2018, 11-01, Volume: 192

    Topics: Adult; Analgesics, Opioid; Benzodiazepines; Buprenorphine; Female; Gabapentin; Humans; Infant; Infan

2018
An Atypical Withdrawal Syndrome in Neonates Prenatally Exposed to Gabapentin and Opioids.
    The Journal of pediatrics, 2017, Volume: 181

    Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid

2017
Effect of gabapentin on cognitive processes in rats not exposed and exposed to tobacco smoke during fetal life.
    Human & experimental toxicology, 2008, Volume: 27, Issue:12

    Topics: Amines; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Cognition; Cyclohexanecar

2008