Page last updated: 2024-10-27

gabapentin and Craniofacial Pain

gabapentin has been researched along with Craniofacial Pain in 20 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the nature of the antinociceptive interaction of systemic administration of a combination of the anticonvulsant gabapentin with the antidepressant nortriptyline, by isobolographic analysis in the formalin orofacial pain test of mice."7.79Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain. ( Miranda, HF; Noriega, V; Prieto, JC; Zanetta, P, 2013)
"This study aims to evaluate the anti-nociceptive effects of ECa 233 and its synergistic effect with gabapentin on chronic neuropathic orofacial pain after 3 weeks infraorbital nerve chronic constriction injury in mice."4.12Anti-nociceptive effects of ECa 233 a standardized extract of Centella asiatica (L.) Urban on chronic neuropathic orofacial pain in mice. ( Buapratoom, A; Khongsombat, O; Tantisira, MH; Wanasuntronwong, A, 2022)
"To evaluate the nature of the antinociceptive interaction of systemic administration of a combination of the anticonvulsant gabapentin with the antidepressant nortriptyline, by isobolographic analysis in the formalin orofacial pain test of mice."3.79Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain. ( Miranda, HF; Noriega, V; Prieto, JC; Zanetta, P, 2013)
"Chronic orofacial pain can greatly improve following treatment of the underlying insomnia, and therefore, re-evaluation of COFP is advised after 1 month of treatment."2.55An update of management of insomnia in patients with chronic orofacial pain. ( Almoznino, G; Benoliel, R; Haviv, Y; Sharav, Y, 2017)
"Trigeminal neuralgia is a unique neuropathic pain disorder with a specific therapy."2.42Management issues of neuropathic trigeminal pain from a medical perspective. ( Watson, CP, 2004)
"Gabapentin is a good alternative therapeutic option to anesthetic blockade."1.43Auriculotemporal Neuralgia: Eight New Cases Report. ( Cuadrado, ML; de la Cruz, C; Garcia-Ptacek, S; Guerrero, AL; Porta-Etessam, J; Ruiz, M, 2016)
" Time-course data for the dose-response effects were analyzed using two-way analysis of variance and the posthoc Tukey-Kramer multiple-comparison test."1.40Antinociceptive effects of mirtazapine, pregabalin, and gabapentin after chronic constriction injury of the infraorbital nerve in rats. ( Hashimoto, R; Hosokawa, K; Mashimo, T; Nakae, A; Nakai, K, 2014)
"Neuropathic and/or neuralgic facial pain occurred in 50% (n = 7)."1.35The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions. ( Garza, I, 2008)
"This report describes a case of chronic facial pain in a patient with this condition which was confirmed radiologically."1.35Diagnosis of osteochondroma of the mandibular condyle in atypical facial pain: a case report. ( Aghabeigi, B; Nasr, IH, 2008)
"Gabapentin is a useful agent for the relief of trigeminal neuralgia and orofacial phantom pain."1.35[Interaction between gabapentin and D-serin in the formalin orofacial test]. ( González, LE; Hernández, L; Quiñónez, B; Silva, E, 2009)
"None of the patients reported any facial pain before surgery or trauma."1.31Facial pain following sinonasal surgery or facial trauma. ( Jones, NS; Khan, OA; Majumdar, S, 2002)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's8 (40.00)29.6817
2010's9 (45.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Buapratoom, A1
Wanasuntronwong, A1
Khongsombat, O1
Tantisira, MH1
Groenke, BR1
Daline, IH1
Nixdorf, DR1
Haribabu, PK1
Eliav, E1
Heir, GM1
Marchiori, ÉC1
Barber, JS1
Williams, WB1
Bui, PQ1
O'Ryan, FS1
Miranda, HF1
Noriega, V1
Zanetta, P1
Prieto, JC1
Nakai, K1
Nakae, A1
Hashimoto, R1
Mashimo, T1
Hosokawa, K1
Alwanni, N1
Altay, MA1
Baur, DA1
Quereshy, FA1
Ruiz, M1
Porta-Etessam, J2
Garcia-Ptacek, S1
de la Cruz, C1
Cuadrado, ML2
Guerrero, AL1
Almoznino, G1
Haviv, Y1
Sharav, Y1
Benoliel, R1
Jacob, S1
Saha, A1
Rajabally, Y1
Garza, I1
Nasr, IH1
Aghabeigi, B1
Galán, L1
Sampedro, A1
Valencia, C1
Quiñónez, B1
Silva, E1
González, LE1
Hernández, L1
Martin, WJ1
Forouzanfar, T1
Hänsel, A1
Watson, CP1
Kimos, P1
Biggs, C1
Mah, J1
Heo, G1
Rashiq, S1
Thie, NM1
Major, PW1
Rosner, H1
Rubin, L1
Kestenbaum, A1
Khan, OA1
Majumdar, S1
Jones, NS1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Erenumab as a Therapeutic Approach for the Management of Painful Chronic Temporomandibular Disorders (TMD)[NCT05162027]Phase 25 participants (Actual)Interventional2022-04-01Terminated (stopped due to Low enrollment rate)
Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain[NCT02339662]Phase 450 participants (Anticipated)Interventional2015-02-28Recruiting
Persistent Postoperative Pain Incidence With Long Term Perioperative Gabapentin Used[NCT02693821]Phase 4122 participants (Actual)Interventional2015-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for gabapentin and Craniofacial Pain

ArticleYear
An update of management of insomnia in patients with chronic orofacial pain.
    Oral diseases, 2017, Volume: 23, Issue:8

    Topics: Amines; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Chronic Pain; Cognitive Behavioral

2017
The efficacy of anticonvulsants on orofacial pain: a systematic review.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:5

    Topics: Amines; Anticonvulsants; Burning Mouth Syndrome; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Ac

2011
Management issues of neuropathic trigeminal pain from a medical perspective.
    Journal of orofacial pain, 2004,Fall, Volume: 18, Issue:4

    Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; C

2004

Trials

2 trials available for gabapentin and Craniofacial Pain

ArticleYear
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Gabapentin adjunctive therapy in neuropathic pain states.
    The Clinical journal of pain, 1996, Volume: 12, Issue:1

    Topics: Acetates; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapen

1996

Other Studies

15 other studies available for gabapentin and Craniofacial Pain

ArticleYear
Anti-nociceptive effects of ECa 233 a standardized extract of Centella asiatica (L.) Urban on chronic neuropathic orofacial pain in mice.
    Journal of ethnopharmacology, 2022, Jan-30, Volume: 283

    Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Chronic Pain; Disease Models, Animal; Dose-Res

2022
SUNCT/SUNA: Case series presenting in an orofacial pain clinic.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:6

    Topics: Adult; Autonomic Nervous System Diseases; Facial Pain; Female; Gabapentin; Headache Disorders; Human

2021
Topical medications for the effective management of neuropathic orofacial pain.
    Journal of the American Dental Association (1939), 2013, Volume: 144, Issue:6

    Topics: Administration, Topical; Amines; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Age

2013
Neuropathic pain following sagittal split ramus osteotomy of the mandible: prevalence, risk factors, and clinical course.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2013, Volume: 71, Issue:12

    Topics: Adult; Age Factors; Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cohort Studies; Cyclo

2013
Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain.
    Journal of orofacial pain, 2013,Fall, Volume: 27, Issue:4

    Topics: Amines; Animals; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Drug Synergism

2013
Antinociceptive effects of mirtazapine, pregabalin, and gabapentin after chronic constriction injury of the infraorbital nerve in rats.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Animals; Cranial Nerve Injuries; Cyclohexanecarbox

2014
First Bite Syndrome After Bilateral Temporomandibular Joint Replacement: Case Report.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2016, Volume: 74, Issue:3

    Topics: Adult; Amines; Analgesics; Arthroplasty, Replacement; Cyclohexanecarboxylic Acids; Facial Pain; Fema

2016
Auriculotemporal Neuralgia: Eight New Cases Report.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:9

    Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapentin; gamma

2016
Post-traumatic short-lasting unilateral headache with cranial autonomic symptoms (SUNA).
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:9

    Topics: Accidents, Traffic; Adult; Amines; Carbamazepine; Conjunctiva; Cyclohexanecarboxylic Acids; Facial P

2008
The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Child; Cyclohexanecarboxylic Acids; Erythema; Fa

2008
Diagnosis of osteochondroma of the mandibular condyle in atypical facial pain: a case report.
    Dental update, 2008, Volume: 35, Issue:10

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; H

2008
Temporal response to bupivacaine bilateral great occipital block in a patient with SUNCT syndrome.
    The journal of headache and pain, 2010, Volume: 11, Issue:2

    Topics: Aged, 80 and over; Amines; Anesthetics, Local; Anticonvulsants; Bupivacaine; Cyclohexanecarboxylic A

2010
[Interaction between gabapentin and D-serin in the formalin orofacial test].
    Investigacion clinica, 2009, Volume: 50, Issue:4

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Interactions; Facial Pain; Gabapentin

2009
[Neuritis of the maxillary nerve. A 55-year-old housewife].
    Praxis, 2004, Sep-29, Volume: 93, Issue:40

    Topics: Amines; Analgesics; Anti-Inflammatory Agents; Cluster Headache; Cranial Nerve Diseases; Cyclohexanec

2004
Facial pain following sinonasal surgery or facial trauma.
    Clinical otolaryngology and allied sciences, 2002, Volume: 27, Issue:3

    Topics: Acetates; Adult; Aged; Amines; Amitriptyline; Analgesics, Non-Narcotic; Carbamazepine; Cyclohexaneca

2002