Page last updated: 2024-10-27

gabapentin and Concussive Convulsion

gabapentin has been researched along with Concussive Convulsion in 4 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" Furthermore, most preclinical antiepileptogenic studies lack information needed for translation, such as dose-blood level relationship, brain target engagement, and dose-response, and many use treatment parameters that cannot be applied clinically, for example, treatment initiation before or at the time of injury and dosing higher than tolerated human equivalent dosing."2.66Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020)
"Gabapentin (GBP) is an anticonvulsant that acts at the α2δ-1 submit of the L-type calcium channel."1.38Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma. ( Barres, BA; Graber, KD; Jin, S; Li, H; McDonald, W; Prince, DA, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Klein, P1
Friedman, A1
Hameed, MQ1
Kaminski, RM1
Bar-Klein, G1
Klitgaard, H1
Koepp, M1
Jozwiak, S1
Prince, DA3
Rotenberg, A1
Twyman, R1
Vezzani, A1
Wong, M1
Löscher, W1
Efendioglu, M1
Basaran, R1
Akca, M1
Ceman, D1
Demirtas, C1
Yildirim, M1
Takahashi, DK1
Jin, S2
Li, H1
Graber, KD1
McDonald, W1
Barres, BA1

Reviews

1 review available for gabapentin and Concussive Convulsion

ArticleYear
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Cef

2020

Other Studies

3 other studies available for gabapentin and Concussive Convulsion

ArticleYear
Combination Therapy of Gabapentin and N-Acetylcysteine Against Posttraumatic Epilepsy in Rats.
    Neurochemical research, 2020, Volume: 45, Issue:8

    Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Anticonvulsants; Antioxidants; Brain Concussion; D

2020
Gabapentin Prevents Progressive Increases in Excitatory Connectivity and Epileptogenesis Following Neocortical Trauma.
    Cerebral cortex (New York, N.Y. : 1991), 2018, 08-01, Volume: 28, Issue:8

    Topics: Animals; Animals, Newborn; Anticonvulsants; Brain Mapping; Disease Models, Animal; Electric Stimulat

2018
Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma.
    Neurobiology of disease, 2012, Volume: 48, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Blotting, Western; Brain Injuries; Cyclohexanecarboxylic Acids; Di

2012