gabapentin has been researched along with Concussive Convulsion in 4 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, most preclinical antiepileptogenic studies lack information needed for translation, such as dose-blood level relationship, brain target engagement, and dose-response, and many use treatment parameters that cannot be applied clinically, for example, treatment initiation before or at the time of injury and dosing higher than tolerated human equivalent dosing." | 2.66 | Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020) |
| "Gabapentin (GBP) is an anticonvulsant that acts at the α2δ-1 submit of the L-type calcium channel." | 1.38 | Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma. ( Barres, BA; Graber, KD; Jin, S; Li, H; McDonald, W; Prince, DA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klein, P | 1 |
| Friedman, A | 1 |
| Hameed, MQ | 1 |
| Kaminski, RM | 1 |
| Bar-Klein, G | 1 |
| Klitgaard, H | 1 |
| Koepp, M | 1 |
| Jozwiak, S | 1 |
| Prince, DA | 3 |
| Rotenberg, A | 1 |
| Twyman, R | 1 |
| Vezzani, A | 1 |
| Wong, M | 1 |
| Löscher, W | 1 |
| Efendioglu, M | 1 |
| Basaran, R | 1 |
| Akca, M | 1 |
| Ceman, D | 1 |
| Demirtas, C | 1 |
| Yildirim, M | 1 |
| Takahashi, DK | 1 |
| Jin, S | 2 |
| Li, H | 1 |
| Graber, KD | 1 |
| McDonald, W | 1 |
| Barres, BA | 1 |
1 review available for gabapentin and Concussive Convulsion
| Article | Year |
|---|---|
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Cef | 2020 |
3 other studies available for gabapentin and Concussive Convulsion
| Article | Year |
|---|---|
Combination Therapy of Gabapentin and N-Acetylcysteine Against Posttraumatic Epilepsy in Rats.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Anticonvulsants; Antioxidants; Brain Concussion; D | 2020 |
Gabapentin Prevents Progressive Increases in Excitatory Connectivity and Epileptogenesis Following Neocortical Trauma.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain Mapping; Disease Models, Animal; Electric Stimulat | 2018 |
Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma.
Topics: Amines; Animals; Anticonvulsants; Blotting, Western; Brain Injuries; Cyclohexanecarboxylic Acids; Di | 2012 |