Page last updated: 2024-10-27

gabapentin and Complications, Pregnancy

gabapentin has been researched along with Complications, Pregnancy in 12 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" We examined the risk of major congenital malformations and cardiac defects associated with gabapentin exposure during the first trimester (T1), and the risk of preeclampsia (PE), preterm birth (PTB), small for gestational age (SGA), and neonatal intensive care unit admission (NICUa) associated with gabapentin exposure early, late, or both early and late in pregnancy."7.96Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. ( Bateman, BT; Cohen, JM; Desai, RJ; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Patorno, E, 2020)
"The objective of this study was to assess the safety of gabapentin (Neurontin) exposure in human pregnancy."7.72Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. ( Montouris, G, 2003)
" GBP plasma concentrations in the neonates declined with an estimated half-life of 14 h."5.33Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy? ( Ohman, I; Tomson, T; Vitols, S, 2005)
" We examined the risk of major congenital malformations and cardiac defects associated with gabapentin exposure during the first trimester (T1), and the risk of preeclampsia (PE), preterm birth (PTB), small for gestational age (SGA), and neonatal intensive care unit admission (NICUa) associated with gabapentin exposure early, late, or both early and late in pregnancy."3.96Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. ( Bateman, BT; Cohen, JM; Desai, RJ; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Patorno, E, 2020)
"The objective of this study was to assess the safety of gabapentin (Neurontin) exposure in human pregnancy."3.72Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. ( Montouris, G, 2003)
" In the last decade, pregnancy registries have been activated by collaborative groups of physicians in Europe (EURAP), North America (NAREP), Australia and India (the latter two recently merged into EURAP), to enroll a large number of exposed women to be monitored prospectively with standardized methods, and by three pharmaceutical companies marketing lamotrigine, gabapentin and vigabatrin, as part of their post-marketing surveillance."3.71Pregnancy registries in epilepsy. ( Annegers, JF; Beghi, E, 2001)
"Epilepsy is one of the most common neurological complications in pregnancy; some women continue to use antiepileptic drugs (AEDs) to control seizures."2.66[Transfer Mechanisms of Compounds between Mother and Fetus/Infant Aimed for Optimized Medication during Pregnancy and Breastfeeding]. ( Furugen, A, 2020)
"Idiopathic restless legs syndrome (RLS) can severely affect quality of life and disturb sleep, so that pharmacological treatment is necessary, especially for elderly patients."2.52Restless legs syndrome-current therapies and management of augmentation. ( Inoue, Y; Paulus, W; Trenkwalder, C; Winkelmann, J, 2015)
" GBP plasma concentrations in the neonates declined with an estimated half-life of 14 h."1.33Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy? ( Ohman, I; Tomson, T; Vitols, S, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Patorno, E1
Hernandez-Diaz, S1
Huybrechts, KF1
Desai, RJ1
Cohen, JM1
Mogun, H1
Bateman, BT1
Furugen, A1
Daugaard, CA1
Sun, Y1
Dreier, JW1
Christensen, J1
Nagandla, K1
De, S1
Trenkwalder, C1
Winkelmann, J1
Inoue, Y2
Paulus, W1
Vanya, M1
Devosa, I1
Szok, D1
Bártfai, G1
Terada, K1
Montouris, G1
Wu, SP1
Shyu, MK1
Liou, HH1
Gau, CS1
Lin, CJ1
Ohman, I1
Vitols, S1
Tomson, T1
Chaudron, LH1
Jefferson, JW1
Beghi, E1
Annegers, JF1

Reviews

5 reviews available for gabapentin and Complications, Pregnancy

ArticleYear
[Transfer Mechanisms of Compounds between Mother and Fetus/Infant Aimed for Optimized Medication during Pregnancy and Breastfeeding].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Volume: 140, Issue:10

    Topics: Anticonvulsants; Benzodiazepines; Biological Transport; Breast Feeding; Cell Line; Epilepsy; Female;

2020
Restless legs syndrome: pathophysiology and modern management.
    Postgraduate medical journal, 2013, Volume: 89, Issue:1053

    Topics: Amines; Anemia; Anticonvulsants; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dopamine Agon

2013
Restless legs syndrome-current therapies and management of augmentation.
    Nature reviews. Neurology, 2015, Volume: 11, Issue:8

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Sy

2015
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
    Orvosi hetilap, 2016, Apr-10, Volume: 157, Issue:15

    Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epileps

2016
Mood stabilizers during breastfeeding: a review.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarbo

2000

Other Studies

7 other studies available for gabapentin and Complications, Pregnancy

ArticleYear
Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset.
    PLoS medicine, 2020, Volume: 17, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Cohort Studies; Female; Gabapentin; Humans; Infant, Small for Ge

2020
Use of antiepileptic drugs in women of fertile age.
    Danish medical journal, 2019, Volume: 66, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Denmark; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Leve

2019
[Clinical application of newer anti-epileptic drugs].
    Rinsho shinkeigaku = Clinical neurology, 2012, Volume: 52, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-

2012
Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:3

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin;

2003
Interaction between anticonvulsants and human placental carnitine transporter.
    Epilepsia, 2004, Volume: 45, Issue:3

    Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techn

2004
Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy?
    Epilepsia, 2005, Volume: 46, Issue:10

    Topics: Amines; Anticonvulsants; Breast Feeding; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fetal Blood;

2005
Pregnancy registries in epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:11

    Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison

2001