Page last updated: 2024-10-27

gabapentin and Complex Regional Pain Syndromes

gabapentin has been researched along with Complex Regional Pain Syndromes in 16 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)

Research Excerpts

ExcerptRelevanceReference
"We report the case of a woman who developed chorea in her neck, trunk, and extremities soon after taking gabapentin as treatment for complex regional pain syndrome Type 1."7.74Chorea as a side effect of gabapentin (Neurontin) in a patient with complex regional pain syndrome Type 1. ( Hauser, RA; Robinson, W; Shimberg, WR; Sullivan, KL; Wilson, MC; Zesiewicz, TA, 2008)
"We know from adult randomised controlled trials that some antiepileptics, such as gabapentin and pregabalin, can be effective in certain chronic pain conditions."4.95Antiepileptic drugs for chronic non-cancer pain in children and adolescents. ( Clinch, J; Cooper, TE; Heathcote, LC; Howard, R; Krane, E; Lord, SM; Schechter, N; Sethna, N; Wiffen, PJ; Wood, C, 2017)
"We report the case of a woman who developed chorea in her neck, trunk, and extremities soon after taking gabapentin as treatment for complex regional pain syndrome Type 1."3.74Chorea as a side effect of gabapentin (Neurontin) in a patient with complex regional pain syndrome Type 1. ( Hauser, RA; Robinson, W; Shimberg, WR; Sullivan, KL; Wilson, MC; Zesiewicz, TA, 2008)
"We report 2 cases of complex regional pain syndrome (CRPS) involving the lower extremity; in both, a sphenopalatine ganglion (SPG) block was performed as part of a pain management program."1.33Complex regional pain syndrome involving the lower extremity: a report of 2 cases of sphenopalatine block as a treatment option. ( Platt, H; Purgavie, K; Quevedo, JP; Strax, TE, 2005)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's8 (50.00)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Grinshpun, G1
Javed, S1
Abdi, S1
Cutts, S1
Gangoo, S1
Srinivasan, SH1
Modi, N1
Pasapula, C1
Power, D1
Cooper, TE2
Heathcote, LC2
Clinch, J2
Gold, JI1
Howard, R2
Lord, SM2
Schechter, N2
Wood, C2
Wiffen, PJ2
Krane, E1
Sethna, N1
Boyacı, A1
Tutoğlu, A1
Boyacı, FN1
Yalçın, Ş1
Dizdarevic, A1
Bremer, N1
Palumbo, A1
Toomay, S1
Singh, K1
Kalva, S1
Feldman, AB1
Saint-Phard, D1
Tuchman, M1
Barrett, JA1
Donevan, S1
Hedberg, TG1
Taylor, CP1
Shah, A1
Kirchner, JS1
Jones, JD1
Albert, DA1
Thadani, V1
Rigby, WF1
Quevedo, JP1
Purgavie, K1
Platt, H1
Strax, TE1
Nordmann, GR1
Lauder, GR1
Grier, DJ1
Zesiewicz, TA1
Shimberg, WR1
Hauser, RA1
Robinson, W1
Wilson, MC1
Sullivan, KL1
Rho, RH1
Brewer, RP1
Lamer, TJ1
Wilson, PR1

Reviews

7 reviews available for gabapentin and Complex Regional Pain Syndromes

ArticleYear
Use of anticonvulsants and antidepressants for treatment of complex regional pain syndrome: a literature review.
    Pain management, 2021, Volume: 11, Issue:2

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Complex Regional Pain Syndromes; Gabapentin;

2021
Complex regional pain syndrome: an evolving perspective.
    Postgraduate medical journal, 2021, Volume: 97, Issue:1146

    Topics: Amputation, Surgical; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Ascorbic Acid; Botuli

2021
Antidepressants for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-05, Volume: 8

    Topics: Abdominal Pain; Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Child; Chronic

2017
Antiepileptic drugs for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-05, Volume: 8

    Topics: Adolescent; Amines; Amitriptyline; Anticonvulsants; Child; Chronic Pain; Complex Regional Pain Syndr

2017
Central sensitization and Ca(V)α₂δ ligands in chronic pain syndromes: pathologic processes and pharmacologic effect.
    The journal of pain, 2010, Volume: 11, Issue:12

    Topics: Amines; Analgesics; Animals; Calcium Channels; Complex Regional Pain Syndromes; Cyclohexanecarboxyli

2010
Complex regional pain syndrome.
    Foot and ankle clinics, 2011, Volume: 16, Issue:2

    Topics: Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroi

2011
Complex regional pain syndrome.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:2

    Topics: Acetates; Algorithms; Amines; Anesthesia, Conduction; Anesthetics, Local; Anti-Inflammatory Agents;

2002

Other Studies

9 other studies available for gabapentin and Complex Regional Pain Syndromes

ArticleYear
Chronic Pain Syndromes: Complex Regional Pain Syndrome.
    FP essentials, 2023, Volume: 533

    Topics: Chronic Pain; Complex Regional Pain Syndromes; Gabapentin; Humans; Ketamine; Physical Therapy Modali

2023
[Complex regional pain syndrome type 1 after fracture of distal phalanx: case report].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2014, Volume: 26, Issue:4

    Topics: Amines; Analgesics; Combined Modality Therapy; Complex Regional Pain Syndromes; Cyclohexanecarboxyli

2014
Cervical Spinal Cord Stimulation with Concomitant Serotonin Norepinephrine Reuptake Inhibitor Therapy Leading to the Serotonin Syndrome.
    Pain medicine (Malden, Mass.), 2017, 06-01, Volume: 18, Issue:6

    Topics: Adult; Analgesics; Cervical Vertebrae; Clonidine; Complex Regional Pain Syndromes; Diclofenac; Drug

2017
Angiography in Complex Regional Pain Syndrome.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:3

    Topics: Amines; Analgesics; Anesthetics, Local; Angiography; Complex Regional Pain Syndromes; Cyclohexanecar

2017
Femoral neck stress fracture complicated by deep venous thrombosis and complex regional pain syndrome: a case report.
    PM & R : the journal of injury, function, and rehabilitation, 2009, Volume: 1, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Adult; Amines; Autonomic Nerve Block; Complex Regional Pain Syndromes;

2009
Unusual case of a swollen painful toe in a young man.
    Arthritis care & research, 2012, Volume: 64, Issue:2

    Topics: Acne Vulgaris; Adult; Amines; Analgesics, Opioid; Anti-Bacterial Agents; Arthritis; Complex Regional

2012
Complex regional pain syndrome involving the lower extremity: a report of 2 cases of sphenopalatine block as a treatment option.
    Archives of physical medicine and rehabilitation, 2005, Volume: 86, Issue:2

    Topics: Adult; Amines; Anticonvulsants; Autonomic Nerve Block; Complex Regional Pain Syndromes; Cyclohexanec

2005
Computed tomography guided lumbar sympathetic block for complex regional pain syndrome in a child: a case report and review.
    European journal of pain (London, England), 2006, Volume: 10, Issue:5

    Topics: Amines; Amitriptyline; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Autonomic N

2006
Chorea as a side effect of gabapentin (Neurontin) in a patient with complex regional pain syndrome Type 1.
    Clinical rheumatology, 2008, Volume: 27, Issue:3

    Topics: Amines; Analgesics; Chorea; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Female; Ga

2008