gabapentin has been researched along with Cocaine-Related Disorders in 14 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Cocaine-Related Disorders: Disorders related or resulting from use of cocaine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Tiagabine significantly reduced cocaine taking behavior compared to placebo or gabapentin among methadone-stabilized cocaine abusers." | 5.12 | Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. ( Desai, R; Gonsai, K; González, G; Kosten, TR; Oliveto, A; Poling, J; Sofuoglu, M, 2007) |
| "Cocaine dependence is a major public health problem with no available robustly effective pharmacotherapy." | 2.79 | Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms. ( Cargile, C; Chopra, MP; Guise, JB; Kosten, TR; Mancino, MJ; McGaugh, J; Oliveto, A; Sanders, N; Thostenson, J; Williams, DK, 2014) |
| "Gabapentin is an anticonvulsant medication that increases human brain GABA levels." | 2.72 | A randomized placebo-controlled trial of gabapentin for cocaine dependence. ( Aharonovich, E; Bisaga, A; Garawi, F; Levin, FR; Nunes, EV; Raby, WN; Rubin, E, 2006) |
| "Gabapentin appeared to be a safe and efficacious medication to reduce cocaine usage in a community sample of psychiatric patients." | 2.71 | Gabapentin reduces cocaine use among addicts from a community clinic sample. ( Coomaraswamy, S; Raby, WN, 2004) |
| "Gabapentin is a gamma-aminobutyric acid (GABA) analogue, with GABAmimetic pharmacological properties." | 1.35 | Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. ( Ashby, CR; Gagare, PD; Gardner, EL; Li, J; Li, X; Peng, XQ; Pratihar, D; Ramachandran, PV; Xi, ZX, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (85.71) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mancino, MJ | 1 |
| McGaugh, J | 1 |
| Chopra, MP | 1 |
| Guise, JB | 1 |
| Cargile, C | 1 |
| Williams, DK | 1 |
| Thostenson, J | 1 |
| Kosten, TR | 2 |
| Sanders, N | 1 |
| Oliveto, A | 2 |
| Horey, JT | 1 |
| Mariani, JJ | 1 |
| Cheng, WY | 1 |
| Bisaga, A | 3 |
| Sullivan, M | 1 |
| Nunes, E | 1 |
| Levin, FR | 2 |
| Raby, WN | 3 |
| Coomaraswamy, S | 1 |
| Berger, SP | 1 |
| Winhusen, TM | 1 |
| Somoza, EC | 1 |
| Harrer, JM | 1 |
| Mezinskis, JP | 1 |
| Leiderman, DB | 1 |
| Montgomery, MA | 1 |
| Goldsmith, RJ | 1 |
| Bloch, DA | 1 |
| Singal, BM | 1 |
| Elkashef, A | 1 |
| Haney, M | 2 |
| Hart, C | 1 |
| Collins, ED | 1 |
| Foltin, RW | 2 |
| Aharonovich, E | 2 |
| Garawi, F | 1 |
| Rubin, E | 2 |
| Nunes, EV | 2 |
| Hasin, DS | 1 |
| Brooks, AC | 1 |
| Liu, X | 1 |
| Filip, M | 1 |
| Frankowska, M | 1 |
| Gołda, A | 1 |
| Zaniewska, M | 1 |
| Vetulani, J | 1 |
| Przegaliński, E | 1 |
| González, G | 1 |
| Desai, R | 1 |
| Sofuoglu, M | 1 |
| Poling, J | 1 |
| Gonsai, K | 1 |
| Hart, CL | 1 |
| Vosburg, SK | 1 |
| Peng, XQ | 1 |
| Li, X | 1 |
| Li, J | 1 |
| Ramachandran, PV | 1 |
| Gagare, PD | 1 |
| Pratihar, D | 1 |
| Ashby, CR | 1 |
| Gardner, EL | 1 |
| Xi, ZX | 1 |
| Myrick, H | 1 |
| Henderson, S | 1 |
| Brady, KT | 1 |
| Malcolm, R | 1 |
| Hyman, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Crack-cocaine Addiction Through Cognitive Neuromodulation of the Prefrontal Cortex Produced by Transcranial Direct Current Stimulation.[NCT01337297] | Phase 1/Phase 2 | 20 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| Neural Mechanistic Explanations for Differential Drug Abuse Treatment Outcomes[NCT01678833] | 7 participants (Actual) | Observational | 2012-07-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
abstinence to the use of crack-cocaine up to 3 months after the completion of two-weeks of treatment sessions with active-tDCS or sham-tDCS. (NCT01337297)
Timeframe: Two days after the end of tDCS treatment (one session every other day, 5 sessions), that is, on the 12nd day from the beginning.
| Intervention | percentage of participants (Number) |
|---|---|
| Active-tDCS | 71.4 |
| Sham-tDCS | 16.6 |
9 trials available for gabapentin and Cocaine-Related Disorders
| Article | Year |
|---|---|
Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; C | 2014 |
Comparison of substance use milestones in cannabis- and cocaine-dependent patients.
Topics: Adult; Age of Onset; Amines; Antidepressive Agents, Second-Generation; Bupropion; Cocaine-Related Di | 2012 |
Gabapentin reduces cocaine use among addicts from a community clinic sample.
Topics: Acetates; Adult; Amines; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Diagnosis, Dual (Ps | 2004 |
A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence.
Topics: Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cocaine-Related Disorders; Cyclohexanecarboxyl | 2005 |
Smoked cocaine discrimination in humans: effects of gabapentin.
Topics: Administration, Inhalation; Adult; Amines; Arousal; Cocaine; Cocaine-Related Disorders; Cyclohexanec | 2005 |
A randomized placebo-controlled trial of gabapentin for cocaine dependence.
Topics: Adult; Amines; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitato | 2006 |
Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients.
Topics: Adult; Amines; Anti-Anxiety Agents; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combine | 2007 |
Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure.
Topics: Adult; Affect; Ambulatory Care; Amines; Arousal; Blood Pressure; Choice Behavior; Cocaine; Cocaine-R | 2007 |
Gabapentin in the treatment of cocaine dependence: a case series.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Behavior, Addictive; Cocaine-Related Disorders | 2001 |
5 other studies available for gabapentin and Cocaine-Related Disorders
| Article | Year |
|---|---|
Cognitive deficits predict low treatment retention in cocaine dependent patients.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognition Disorders; Cognitive Behavioral Therapy; Cyclohe | 2006 |
Cognitive deficits predict low treatment retention in cocaine dependent patients.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognition Disorders; Cognitive Behavioral Therapy; Cyclohe | 2006 |
Cognitive deficits predict low treatment retention in cocaine dependent patients.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognition Disorders; Cognitive Behavioral Therapy; Cyclohe | 2006 |
Cognitive deficits predict low treatment retention in cocaine dependent patients.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognition Disorders; Cognitive Behavioral Therapy; Cyclohe | 2006 |
Various GABA-mimetic drugs differently affect cocaine-evoked hyperlocomotion and sensitization.
Topics: Amines; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic | 2006 |
Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats.
Topics: Amines; Animals; Anti-Anxiety Agents; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acid | 2008 |
Gabapentin therapy for cocaine cravings.
Topics: Acetates; Adult; Amines; Anticonvulsants; Behavior, Addictive; Cocaine-Related Disorders; Cyclohexan | 2000 |
A 28-year-old man addicted to cocaine.
Topics: Acetates; Adult; Amines; Brain; Cocaine-Related Disorders; Cost of Illness; Crack Cocaine; Cyclohexa | 2001 |