Page last updated: 2024-10-27

gabapentin and Chronic Disease

gabapentin has been researched along with Chronic Disease in 145 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal reflux-induced chronic cough."9.30Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough. ( Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M, 2019)
" Gabapentin (a GABA analogue) is efficacious and often well tolerated in other chronic pain conditions."9.27GaPP2, a multicentre randomised controlled trial of the efficacy of gabapentin for the management of chronic pelvic pain in women: study protocol. ( Baranowski, A; Bhattacharya, S; Birch, J; Cheong, Y; Cregg, R; Daniels, J; Hewitt, CA; Horne, AW; Macfarlane, GJ; Middleton, L; Szubert, W; Tracey, I; Vincent, K; Williams, ACC, 2018)
" Adults with refractory chronic cough (>8 weeks' duration) without active respiratory disease or infection were randomly assigned to receive gabapentin (maximum tolerable daily dose of 1800 mg) or matching placebo for 10 weeks."9.16Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. ( Birring, SS; Gibson, PG; Ryan, NM, 2012)
"To evaluate the adequacy of a low-dose combination of oxycodone and paracetamol (acetaminophen) in patients with multimodal, chronic, non-malignant pain using the Pain Management Index (PMI)."9.14Adequacy assessment of oxycodone/paracetamol (acetaminophen) in multimodal chronic pain : a prospective observational study. ( Bertini, L; Carucci, A; Gatti, A; Mammucari, M; Occhioni, R; Sabato, AF, 2009)
"The purpose of this, open-label, non-comparative study, was to evaluate the efficacy on quality of life and the efficacy of gabapentin monotherapy in patients with chronic radiculopathy."9.14Gabapentin monotherapy in patients with chronic radiculopathy: the efficacy and impact on life quality. ( Deniz, O; Erdal, A; Gureser, G; Karatay, S; Senel, K; Ugur, M; Yildirim, K, 2009)
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception."9.12Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006)
"The aim of this study was to compare the efficacy and side effects of gabapentin, amitriptyline, and their combination in women with chronic pelvic pain."9.11Chronic pelvic pain treated with gabapentin and amitriptyline: a randomized controlled pilot study. ( Ellend, A; Frickey, N; Gleiss, A; Kozek-Langenecker, SA; Kress, HG; Sator-Katzenschlager, SM; Scharbert, G, 2005)
"To assess the effectiveness and safety of the lidocaine patch 5%, a targeted peripheral analgesic, in the treatment of postherpetic neuralgia, painful diabetic neuropathy, and low back pain patients with incomplete responses to their current analgesic treatment regimen containing gabapentin."9.10Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain. ( Drass, M; Nalamachu, S; Patel, N; White, WT, 2003)
"A retrospective audit of the perceived efficacy and tolerability of adjunctive gabapentin (GBT) therapy in patients with intractable epilepsy was carried out."9.09An audit of the perceived efficacy and tolerability of gabapentin therapy in an out-patient cohort with chronic epilepsy. ( Duncan, JS; Langan, Y; Sander, JW, 1999)
"To assess the efficacy and safety of low doses of gabapentin in cases of chronic daily headache."9.09Low doses of gabapentin may be helpful in the management of chronic daily headache. ( Carrazana, EJ; Fragoso, YD, 2000)
"Recent developments in the treatment of cough include the use of speech pathology and pharmacotherapy with gabapentin."8.91Gabapentin in chronic cough. ( Gibson, PG; Vertigan, AE, 2015)
"To assess the analgesic efficacy and adverse effects of gabapentin in chronic neuropathic pain and fibromyalgia."8.90Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Moore, RA; Rice, AS; Toelle, T; Wiffen, PJ, 2014)
"Twenty-nine studies (3571 participants), studied gabapentin at daily doses of 1200 mg or more in 12 chronic pain conditions; 78% of participants were in studies of postherpetic neuralgia, painful diabetic neuropathy or mixed neuropathic pain."8.87Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; McQuay, HJ; Moore, RA; Wiffen, PJ, 2011)
"Gabapentin was initially developed as an antiepileptic drug but was later discovered to be an effective treatment of neuropathic pain."8.86Gabapentin for the treatment of cancer-related pain syndromes. ( Bar Ad, V, 2010)
"To evaluate the analgesic effectiveness and adverse effects of gabapentin for pain management in clinical practice."8.82Gabapentin for acute and chronic pain. ( Edwards, JE; McQuay, HJ; Moore, RA; Wiffen, PJ, 2005)
"In the present work, we investigated the antinociceptive effect of gabapentin in a chronic myositis model and its interference in spinal glial cells."7.85Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. ( Chacur, M; Freitas, MF; Rocha, IR; Rosa, AS, 2017)
"Response to gabapentin was defined by physician-documented subjective patient report of improvement in cough symptoms."7.85Unilateral Laryngoscopic Findings Associated With Response to Gabapentin in Patients With Chronic Cough. ( Dibildox, D; Giliberto, JP; Merati, A, 2017)
"The aim of this study was to assess the role of adding gabapentin (Neurontin) to the prescription of patients with opiate resistant pain as a result of critical limb ischaemia (CLI)."7.76Gabapentin (Neurontin) improves pain scores of patients with critical limb ischaemia: an observational study. ( Lewis, MH; Morris-Stiff, G, 2010)
"The anticonvulsant gabapentin (GBP) has been shown effective for the treatment of neuropathic pain, although its mechanism of action remains unclear."7.73Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. ( Aiyar, J; Anker, N; Belley, M; Bristow, L; Campbell, B; Cohen, C; Park, KT; Ren, K; Stearns, B; Urban, MO, 2005)
"To present two years of experience in the use of gabapentin for the alleviation of neuropathic pain in spinal cord injury patients."7.71Gabapentin for neuropathic pain following spinal cord injury. ( Brown, DJ; Cooper, N; Frauman, AG; Hill, ST; Kirsa, SW; Lim, TC; To, TP, 2002)
"To compare the long-term retention of gabapentin (GBP), lamotrigine (LTG), and vigabatrin (VGB) by patients with chronic epilepsy and the reasons for treatment discontinuation."7.70The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy. ( Chadwick, DW; Fenwick, PB; Mawer, GE; Sander, JW; Wong, IC, 1999)
"We sought to determine the long-term retention rates of lamotrigine (LTG), gabapentin (GBP), and topiramate (TPM) therapy for patients at a tertiary referral clinic for chronic, refractory epilepsy."7.70Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy. ( Lhatoo, SD; Polizzi, G; Sander, JW; Wong, IC, 2000)
"Chronic pruritus is a distressing symptom that is often refractory to treatment."6.53Gabapentin and pregabalin for the treatment of chronic pruritus. ( Kwatra, SG; Matsuda, KM; Schonfeld, AR; Sharma, D, 2016)
"Gabapentin has been shown to cause minimal to no toxicity in overdose."6.52A review on the efficacy and safety of gabapentin in the treatment of chronic cough. ( Ryan, NM, 2015)
"Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist."5.46Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017)
"Gabapentin treatment significantly and reversibly changed the responses, consistent with the attenuation of the abnormal sensory behavior, and the attenuated responses lasted for the duration of the drug effect (up to 6 h)."5.31Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin. ( Hulsebosch, CE; McAdoo, DJ; Perez-Polo, JR; Taylor, CP; Westlund, KN; Xu, GY, 2000)
"To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal reflux-induced chronic cough."5.30Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough. ( Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M, 2019)
" Gabapentin (a GABA analogue) is efficacious and often well tolerated in other chronic pain conditions."5.27GaPP2, a multicentre randomised controlled trial of the efficacy of gabapentin for the management of chronic pelvic pain in women: study protocol. ( Baranowski, A; Bhattacharya, S; Birch, J; Cheong, Y; Cregg, R; Daniels, J; Hewitt, CA; Horne, AW; Macfarlane, GJ; Middleton, L; Szubert, W; Tracey, I; Vincent, K; Williams, ACC, 2018)
"Compared with gabapentin, duloxetine has no obvious advantage in the treatment of diabetic peripheral neuralgia, but it has less side effects and significantly higher safety."5.22Comparison of the Efficacy and Safety of Duloxetine and Gabapentin in Diabetic Peripheral Neuropathic Pain: A Meta-Analysis. ( Cui, J; Jiang, L; Xiong, Y, 2022)
" Adults with refractory chronic cough (>8 weeks' duration) without active respiratory disease or infection were randomly assigned to receive gabapentin (maximum tolerable daily dose of 1800 mg) or matching placebo for 10 weeks."5.16Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. ( Birring, SS; Gibson, PG; Ryan, NM, 2012)
"The purpose of this study was to evaluate the analgesic effects of perioperative gabapentin on postoperative acute and chronic pain after coronary artery bypass graft (CABG) surgery with median sternotomy and internal mammary artery harvesting."5.15The effects of gabapentin on acute and chronic postoperative pain after coronary artery bypass graft surgery. ( Onan, B; Selcuk, I; Sen, H; Turan, A; Ucak, A; Yilmaz, AT, 2011)
"To evaluate the adequacy of a low-dose combination of oxycodone and paracetamol (acetaminophen) in patients with multimodal, chronic, non-malignant pain using the Pain Management Index (PMI)."5.14Adequacy assessment of oxycodone/paracetamol (acetaminophen) in multimodal chronic pain : a prospective observational study. ( Bertini, L; Carucci, A; Gatti, A; Mammucari, M; Occhioni, R; Sabato, AF, 2009)
"The purpose of this, open-label, non-comparative study, was to evaluate the efficacy on quality of life and the efficacy of gabapentin monotherapy in patients with chronic radiculopathy."5.14Gabapentin monotherapy in patients with chronic radiculopathy: the efficacy and impact on life quality. ( Deniz, O; Erdal, A; Gureser, G; Karatay, S; Senel, K; Ugur, M; Yildirim, K, 2009)
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception."5.12Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006)
" Fifty patients scheduled for breast cancer surgery were blindly randomized to receive gabapentin, eutectic mixture of local anesthetics cream, and ropivacaine in the wound or three placebos."5.11Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer. ( Fassoulaki, A; Melemeni, A; Sarantopoulos, C; Triga, A, 2005)
"The aim of this study was to compare the efficacy and side effects of gabapentin, amitriptyline, and their combination in women with chronic pelvic pain."5.11Chronic pelvic pain treated with gabapentin and amitriptyline: a randomized controlled pilot study. ( Ellend, A; Frickey, N; Gleiss, A; Kozek-Langenecker, SA; Kress, HG; Sator-Katzenschlager, SM; Scharbert, G, 2005)
"To assess the effectiveness and safety of the lidocaine patch 5%, a targeted peripheral analgesic, in the treatment of postherpetic neuralgia, painful diabetic neuropathy, and low back pain patients with incomplete responses to their current analgesic treatment regimen containing gabapentin."5.10Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain. ( Drass, M; Nalamachu, S; Patel, N; White, WT, 2003)
"A retrospective audit of the perceived efficacy and tolerability of adjunctive gabapentin (GBT) therapy in patients with intractable epilepsy was carried out."5.09An audit of the perceived efficacy and tolerability of gabapentin therapy in an out-patient cohort with chronic epilepsy. ( Duncan, JS; Langan, Y; Sander, JW, 1999)
"To assess the efficacy and safety of low doses of gabapentin in cases of chronic daily headache."5.09Low doses of gabapentin may be helpful in the management of chronic daily headache. ( Carrazana, EJ; Fragoso, YD, 2000)
", opioids and gabapentin) are centrally-acting drugs primarily used for pain and neuropathic conditions; they were not designed for cough and have limitations with respect to efficacy and safety."5.05Pharmacotherapeutic Options for Chronic Refractory Cough. ( Chung, KF; Song, WJ, 2020)
" Most studies used oral gabapentin or gabapentin encarbil at doses of 1200 mg or more daily in different neuropathic pain conditions, predominantly postherpetic neuralgia and painful diabetic neuropathy."4.95Gabapentin for chronic neuropathic pain in adults. ( Bell, RF; Derry, S; Moore, RA; Phillips, T; Rice, AS; Tölle, TR; Wiffen, PJ, 2017)
"With anticonvulsant, anxiolytic, and analgesic properties, pregabalin has been evaluated for neuropathic pain and fibromyalgia (FM)."4.91A systematic review of pharmacoeconomic studies for pregabalin. ( Huelin, R; Khankhel, Z; Mould, J; Parker, L; Wasiak, R, 2015)
"Recent developments in the treatment of cough include the use of speech pathology and pharmacotherapy with gabapentin."4.91Gabapentin in chronic cough. ( Gibson, PG; Vertigan, AE, 2015)
"To assess the analgesic efficacy and adverse effects of gabapentin in chronic neuropathic pain and fibromyalgia."4.90Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Moore, RA; Rice, AS; Toelle, T; Wiffen, PJ, 2014)
"The goal of this systematic review was to examine the evidence for the use of the neuromodulating agents, amitriptyline, gabapentin, pregabalin, and baclofen, in the management of chronic, idiopathic cough patients."4.89Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review. ( Cohen, SM; Misono, S, 2013)
"Twenty-nine studies (3571 participants), studied gabapentin at daily doses of 1200 mg or more in 12 chronic pain conditions; 78% of participants were in studies of postherpetic neuralgia, painful diabetic neuropathy or mixed neuropathic pain."4.87Gabapentin for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; McQuay, HJ; Moore, RA; Wiffen, PJ, 2011)
"Gabapentin was initially developed as an antiepileptic drug but was later discovered to be an effective treatment of neuropathic pain."4.86Gabapentin for the treatment of cancer-related pain syndromes. ( Bar Ad, V, 2010)
"To evaluate the analgesic effectiveness and adverse effects of gabapentin for pain management in clinical practice."4.82Gabapentin for acute and chronic pain. ( Edwards, JE; McQuay, HJ; Moore, RA; Wiffen, PJ, 2005)
"Objective To evaluate the short- and long-term effects of tricyclic antidepressants (TCAs) and gabapentin in the treatment of unexplained chronic cough (UCC)."3.88Short- and Long-term Effects of Neuromodulators for Unexplained Chronic Cough. ( Adessa, M; Benninger, MS; Bowen, AJ; Bryson, PC; Contrera, K; Kaltenbach, J; Milstein, CF; Nowacki, AS; Taliercio, R; Trask, D, 2018)
"In the present work, we investigated the antinociceptive effect of gabapentin in a chronic myositis model and its interference in spinal glial cells."3.85Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. ( Chacur, M; Freitas, MF; Rocha, IR; Rosa, AS, 2017)
"Response to gabapentin was defined by physician-documented subjective patient report of improvement in cough symptoms."3.85Unilateral Laryngoscopic Findings Associated With Response to Gabapentin in Patients With Chronic Cough. ( Dibildox, D; Giliberto, JP; Merati, A, 2017)
"The aim of this study was to assess the role of adding gabapentin (Neurontin) to the prescription of patients with opiate resistant pain as a result of critical limb ischaemia (CLI)."3.76Gabapentin (Neurontin) improves pain scores of patients with critical limb ischaemia: an observational study. ( Lewis, MH; Morris-Stiff, G, 2010)
"Although this is a small study, it appears that gabapentin and nortriptyline are effective in the treatment of idiopathic chronic orchialgia but not post-vasectomy pain."3.74Chronic orchialgia: consider gabapentin or nortriptyline before considering surgery. ( Lee, LK; Miller, B; Sinclair, AM, 2007)
"The anticonvulsant gabapentin (GBP) has been shown effective for the treatment of neuropathic pain, although its mechanism of action remains unclear."3.73Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. ( Aiyar, J; Anker, N; Belley, M; Bristow, L; Campbell, B; Cohen, C; Park, KT; Ren, K; Stearns, B; Urban, MO, 2005)
"A pharmacokinetic-pharmacodynamic (PK/PD) model relating pain relief to gabapentin plasma concentrations was derived from a phase 3 study."3.72The use of clinical trial simulation to support dose selection: application to development of a new treatment for chronic neuropathic pain. ( Cook, JA; Ewy, WE; Lockwood, PA; Mandema, JW, 2003)
"A series of mutual prodrugs derived from gabapentin, pregabalin, memantine, venlafaxine were synthesized and their pharmacological properties to treat neuropathic pain were investigated in a rat model of chronic sciatic nerve constriction injury (CCI)."3.72Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury. ( Bo-Hua, Z; He, L; Hong-Ju, Y; Jun-Wei, W; Nan, Z; Wei-Guo, S; Wei-Xiu, Y; Zhe-Hui, G; Zheng-Hua, G; Zhi-Pu, L; Zhong-Wei, J, 2004)
"To present two years of experience in the use of gabapentin for the alleviation of neuropathic pain in spinal cord injury patients."3.71Gabapentin for neuropathic pain following spinal cord injury. ( Brown, DJ; Cooper, N; Frauman, AG; Hill, ST; Kirsa, SW; Lim, TC; To, TP, 2002)
"To compare the long-term retention of gabapentin (GBP), lamotrigine (LTG), and vigabatrin (VGB) by patients with chronic epilepsy and the reasons for treatment discontinuation."3.70The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy. ( Chadwick, DW; Fenwick, PB; Mawer, GE; Sander, JW; Wong, IC, 1999)
"We sought to determine the long-term retention rates of lamotrigine (LTG), gabapentin (GBP), and topiramate (TPM) therapy for patients at a tertiary referral clinic for chronic, refractory epilepsy."3.70Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy. ( Lhatoo, SD; Polizzi, G; Sander, JW; Wong, IC, 2000)
"The novel anti-epileptic drugs lamotrigine, felbamate and gabapentin were compared in rat experimental models of acute (tail flick) and chronic pain: the chronic constriction injury and spinal nerve ligation models."3.69The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain. ( Fontana, DJ; Gogas, KR; Hedley, LR; Hunter, JC; Jacobson, LO; Kassotakis, L; Thompson, J, 1997)
" The outcome measures included scores: (1) for the improvement in the degree of sleep interference score; (2) for the improvement in sleep quality; (3) for the rate of poor sleep quality; (4) for the rate awakenings of >5 per night; and (5) for the incidence of adverse reactions."3.01Efficacy and Safety of Gabapentin in Improving Sleep Quality of Patients with Sensory Nervous System Diseases: A Meta-Analysis. ( Jiang, W; Li, W; Ma, M; Shen, Y, 2023)
" Higher oral dosing and longer treatment regimens of gabapentin may be indicated for the treatment of chronic musculoskeletal pain in horses."2.94Efficacy of orally administered gabapentin in horses with chronic thoracic limb lameness. ( Bauck, AG; Gilliam, LL; Kembel, SL; Schoonover, MJ; Taylor, JD; Young, JM, 2020)
"Assessment of postoperative pain at 1, 3 and 6 months was carried out with an 11-point numerical rating scale; 0 indicating 'no pain' and 10 indicating 'worst pain imaginable'."2.74The effects of gabapentin on acute and chronic pain after inguinal herniorrhaphy. ( Dağli, G; Inangil, G; Ozkan, S; Sen, H; Senol, MG; Sizlan, A; Sücüllü, I; Yanarateş, O, 2009)
"Chronic neuropathic pain occurs in 10-15% of patients with neuroborreliosis and is difficult to treat."2.71Gabapentin for the symptomatic treatment of chronic neuropathic pain in patients with late-stage lyme borreliosis: a pilot study. ( Hofmann, H; Ring, J; Weissenbacher, S, 2005)
"Cough is a common respiratory symptom that is considered to be chronic when it lasts more than eight weeks."2.66Management of chronic refractory cough in adults. ( Beghè, B; Fabbri, LM; Papi, A; Spanevello, A; Visca, D, 2020)
"Mycophenolic acid was detected in all cats."2.61 ( Abrams, G; Adolfsson, E; Agarwal, PK; Akkan, AG; Al Alhareth, NS; Alves, VGL; Armentano, R; Bahroos, E; Baig, M; Baldridge, KK; Barman, S; Bartolucci, C; Basit, A; Bertoli, SV; Bian, L; Bigatti, G; Bobenko, AI; Boix, PP; Bokulic, T; Bolink, HJ; Borowiec, J; Bulski, W; Burciaga, J; Butt, NS; Cai, AL; Campos, AM; Cao, G; Cao, Y; Čapo, I; Caruso, ML; Chao, CT; Cheatum, CM; Chelminski, K; Chen, AJW; Chen, C; Chen, CH; Chen, D; Chen, G; Chen, H; Chen, LH; Chen, R; Chen, RX; Chen, X; Cherdtrakulkiat, R; Chirvony, VS; Cho, JG; Chu, K; Ciurlino, D; Coletta, S; Contaldo, G; Crispi, F; Cui, JF; D'Esposito, M; de Biase, S; Demir, B; Deng, W; Deng, Z; Di Pinto, F; Domenech-Ximenos, B; Dong, G; Drácz, L; Du, XJ; Duan, LJ; Duan, Y; Ekendahl, D; Fan, W; Fang, L; Feng, C; Followill, DS; Foreman, SC; Fortunato, G; Frew, R; Fu, M; Gaál, V; Ganzevoort, W; Gao, DM; Gao, X; Gao, ZW; Garcia-Alvarez, A; Garza, MS; Gauthier, L; Gazzaz, ZJ; Ge, RS; Geng, Y; Genovesi, S; Geoffroy, V; Georg, D; Gigli, GL; Gong, J; Gong, Q; Groeneveld, J; Guerra, V; Guo, Q; Guo, X; Güttinger, R; Guyo, U; Haldar, J; Han, DS; Han, S; Hao, W; Hayman, A; He, D; Heidari, A; Heller, S; Ho, CT; Ho, SL; Hong, SN; Hou, YJ; Hu, D; Hu, X; Hu, ZY; Huang, JW; Huang, KC; Huang, Q; Huang, T; Hwang, JK; Izewska, J; Jablonski, CL; Jameel, T; Jeong, HK; Ji, J; Jia, Z; Jiang, W; Jiang, Y; Kalumpha, M; Kang, JH; Kazantsev, P; Kazemier, BM; Kebede, B; Khan, SA; Kiss, J; Kohen, A; Kolbenheyer, E; Konai, MM; Koniarova, I; Kornblith, E; Krawetz, RJ; Kreouzis, T; Kry, SF; Laepple, T; Lalošević, D; Lan, Y; Lawung, R; Lechner, W; Lee, KH; Lee, YH; Leonard, C; Li, C; Li, CF; Li, CM; Li, F; Li, J; Li, L; Li, S; Li, X; Li, Y; Li, YB; Li, Z; Liang, C; Lin, J; Lin, XH; Ling, M; Link, TM; Liu, HH; Liu, J; Liu, M; Liu, W; Liu, YP; Lou, H; Lu, G; Lu, M; Lun, SM; Ma, Z; Mackensen, A; Majumdar, S; Martineau, C; Martínez-Pastor, JP; McQuaid, JR; Mehrabian, H; Meng, Y; Miao, T; Miljković, D; Mo, J; Mohamed, HSH; Mohtadi, M; Mol, BWJ; Moosavi, L; Mosdósi, B; Nabu, S; Nava, E; Ni, L; Novakovic-Agopian, T; Nyamunda, BC; Nyul, Z; Önal, B; Özen, D; Özyazgan, S; Pajkrt, E; Palazon, F; Park, HW; Patai, Á; Patai, ÁV; Patzke, GR; Payette, G; Pedoia, V; Peelen, MJCS; Pellitteri, G; Peng, J; Perea, RJ; Pérez-Del-Rey, D; Popović, DJ; Popović, JK; Popović, KJ; Posecion, L; Povall, J; Prachayasittikul, S; Prachayasittikul, V; Prat-González, S; Qi, B; Qu, B; Rakshit, S; Ravelli, ACJ; Ren, ZG; Rivera, SM; Salo, P; Samaddar, S; Samper, JLA; Samy El Gendy, NM; Schmitt, N; Sekerbayev, KS; Sepúlveda-Martínez, Á; Sessolo, M; Severi, S; Sha, Y; Shen, FF; Shen, X; Shen, Y; Singh, P; Sinthupoom, N; Siri, S; Sitges, M; Slovak, JE; Solymosi, N; Song, H; Song, J; Song, M; Spingler, B; Stewart, I; Su, BL; Su, JF; Suming, L; Sun, JX; Tantimavanich, S; Tashkandi, JM; Taurbayev, TI; Tedgren, AC; Tenhunen, M; Thwaites, DI; Tibrewala, R; Tomsejm, M; Triana, CA; Vakira, FM; Valdez, M; Valente, M; Valentini, AM; Van de Winckel, A; van der Lee, R; Varga, F; Varga, M; Villarino, NF; Villemur, R; Vinatha, SP; Vincenti, A; Voskamp, BJ; Wang, B; Wang, C; Wang, H; Wang, HT; Wang, J; Wang, M; Wang, N; Wang, NC; Wang, Q; Wang, S; Wang, X; Wang, Y; Wang, Z; Wen, N; Wesolowska, P; Willis, M; Wu, C; Wu, D; Wu, L; Wu, X; Wu, Z; Xia, JM; Xia, X; Xia, Y; Xiao, J; Xiao, Y; Xie, CL; Xie, LM; Xie, S; Xing, Z; Xu, C; Xu, J; Yan, D; Yan, K; Yang, S; Yang, X; Yang, XW; Ye, M; Yin, Z; Yoon, N; Yoon, Y; Yu, H; Yu, K; Yu, ZY; Zhang, B; Zhang, GY; Zhang, H; Zhang, J; Zhang, M; Zhang, Q; Zhang, S; Zhang, W; Zhang, X; Zhang, Y; Zhang, YW; Zhang, Z; Zhao, D; Zhao, F; Zhao, P; Zhao, W; Zhao, Z; Zheng, C; Zhi, D; Zhou, C; Zhou, FY; Zhu, D; Zhu, J; Zhu, Q; Zinyama, NP; Zou, M; Zou, Z, 2019)
"Chronic pruritus is a distressing symptom that is often refractory to treatment."2.53Gabapentin and pregabalin for the treatment of chronic pruritus. ( Kwatra, SG; Matsuda, KM; Schonfeld, AR; Sharma, D, 2016)
"Chronic refractory cough has factors in common with laryngeal hypersensitivity syndromes and chronic pain syndromes, and these similarities help to shed light on the pathophysiology of the condition."2.52Management of chronic refractory cough. ( Gibson, PG; Vertigan, AE, 2015)
"Gabapentin has been shown to cause minimal to no toxicity in overdose."2.52A review on the efficacy and safety of gabapentin in the treatment of chronic cough. ( Ryan, NM, 2015)
"Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation."2.47Anticonvulsants for tinnitus. ( Hoekstra, CE; Rovers, MM; Rynja, SP; van Zanten, GA, 2011)
"Some mechanisms of the development of neuropathic pain have been proposed; 1) sprouting of A beta fibers to the superficial layer of the dorsal horn, 2) ectopic discharge in the dorsal root ganglion and/or in neuroma at the nerve stump, 3) spinal sensitization."2.44[Mechanisms of the development of neuropathic pain and its treatment]. ( Yamamoto, T, 2008)
"Chronic pain is now viewed as a biopsychosocial phenomenon, in which biological, psychological, and social factors are at work."2.44Practical management strategies for the chronic pain patient. ( Forde, G; Stanos, S, 2007)
"neuropathic pain) is not very satisfactorily managed."2.44[Central and peripheral mechanisms in antinociception: current and future perspectives]. ( Fürst, Z, 2008)
"Persistent hiccups have been reported to occur occasionally during rehabilitation hospitalizations."2.44Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature. ( Browne, BA; Schuchmann, JA, 2007)
"Gabapentin is a second generation anticonvulsant that is effective in the treatment of chronic neuropathic pain."2.44Gabapentin: a multimodal perioperative drug? ( Irwin, MG; Kong, VK, 2007)
"Migraine and headache studies are excluded in this revision."2.43Anticonvulsant drugs for acute and chronic pain. ( Carroll, D; Collins, S; Jadad, A; McQuay, H; Moore, A; Wiffen, P, 2005)
" Thus, monitoring and dosage adjustment are required, without discontinuation of the drug."2.43Therapeutic management of chronic neuropathic pain: an examination of pharmacologic treatment. ( Argyra, E; Moka, E; Siafaka, I; Vadalouca, A; Vrachnou, E, 2006)
"Managing patients with chronic neuropathic pain is a common clinical challenge due to variability in individual symptoms, mechanisms, and treatment responses."2.42Diagnosis and management of neuropathic pain: a balanced approach to treatment. ( Nicholson, BD, 2003)
"Lamotrigine has demonstrated efficacy in delaying time to depressive relapse."2.42Rethinking the treatment paradigm for bipolar depression: the importance of long-term management. ( Baldassano, CF; Ballas, CA; O'Reardon, JP, 2004)
"Patients completed a daily postoperative pain and medication log."1.62Preoperative Gabapentin Administration and Its Impact on Postoperative Opioid Requirement and Pain in Sinonasal Surgery. ( Beliveau, AM; Gill, AS; Hwang, JC; Steele, TO; Strong, EB; Virani, FR; Wilson, MD, 2021)
"Gabapentin (GBP) is an established drug that has been used in the management of symptoms of neuropathy but it is associated with unwanted side effects such as sedation and motor incoordination."1.62A novel gabapentin analogue assuages neuropathic pain response in chronic sciatic nerve constriction model in rats. ( Ahmad, N; Akbar, S; Amin, MU; Islam, NU; Khurram, M; Sewell, RDE; Shahid, M; Subhan, F; Ullah, I; Ullah, N; Ullah, R, 2021)
" As only a minority of respondents felt comfortable prescribing these drugs, more education on effective and safe dosing is needed."1.51Use of Systemic Treatment in Patients with Chronic Pruritus: A Survey of Dermatologists in the Netherlands. ( Kamsteeg, M; Kouwenhoven, TA; van de Kerkhof, PCM, 2019)
"Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist."1.46Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017)
"Gabapentin was used by 45% as first-, second-, or third-line treatment."1.46International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis. ( Bieber, BA; Ecder, T; Graham-Brown, M; Hasegawa, T; Kleophas, W; Larkina, M; Pisoni, RL; Rayner, HC; Robinson, BM; Tentori, F; van der Veer, SN; Wang, M, 2017)
"Gabapentin failed to suppress the scratching behavior induced by the intradermal injection of compound 48/80 in normal mice."1.37Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice. ( Manabe, H; Matsumoto, Y; Miura, H; Tsukumo, Y; Yano, H, 2011)
"In rats with four ligatures, prominent mechanical allodynia and thermal hyperalgesia developed; these behavioral signs were not prominent in rats with two ligatures."1.37Pharmacological and behavioral characterization of the saphenous chronic constriction injury model of neuropathic pain in rats. ( Buldum, D; Gunduz, O; Guven, R; Oltulu, C; Ulugol, A, 2011)
"The effect of disc degeneration on behavioral measures of chronic pain has not been evaluated in this model."1.37Behavioral signs of chronic back pain in the SPARC-null mouse. ( Millecamps, M; Sage, EH; Stone, LS; Tajerian, M, 2011)
"Chronic migraine is an important public health problem."1.36Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials. ( D'Amico, D, 2010)
"Anxiety and depression are often also present."1.35Fibromyalgia: poorly understood; treatments are disappointing. ( , 2009)
"CCI also evoked mechanical allodynia that was fully developed on a week post-operation, but showed no recovery for at least 8 weeks."1.35Pharmacological characteristics of the hind paw weight bearing difference induced by chronic constriction injury of the sciatic nerve in rats. ( Kurebayashi, Y; Nakazato-Imasato, E, 2009)
"Pelvic pain was detected 5 days after antigen instillation and was sustained beyond 30 days, indicating the development of chronic pain."1.35Experimental autoimmune prostatitis induces chronic pelvic pain. ( Rudick, CN; Schaeffer, AJ; Thumbikat, P, 2008)
"The severe burning pain, deep pressure-like pain, and deep mechanical allodynia, which presented over the contralateral side to the TBI, were successfully relieved with motor cortex stimulation (MCS)."1.33Motor cortex stimulation for central pain following a traumatic brain injury. ( Choi, ES; Hong, JT; Lee, SW; Son, BC; Sung, JH, 2006)
"Gabapentin is an anticonvulsant that successfully treats many neuropathic pain syndromes, although the mechanism of its antihyperalgesic action remains elusive."1.33Evidence that gabapentin reduces neuropathic pain by inhibiting the spinal release of glutamate. ( Coderre, TJ; Kumar, N; Lefebvre, CD; Yu, JS, 2005)
"Six children with cerebral palsy are presented who developed neuropathic pain following multilevel orthopedic surgery."1.33Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review. ( Lauder, GR; White, MC, 2005)
"Gabapentin has been shown to be useful in treatment of different conditions which may be caused by increased neuronal excitability."1.32Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin. ( Haller, H; Leblhuber, F; Schmidhammer, R; Trenkler, J, 2003)
"SCI gabapentin-treated rats did not display differences in total rearing time until PSD 28 and a significant difference in total activity of all measured parameters was not seen until PSD 60."1.31Changes in exploratory behavior as a measure of chronic central pain following spinal cord injury. ( Grady, JJ; Hulsebosch, CE; Mills, CD, 2001)
"Gabapentin was effective in approximately 50% of pretreated patients with intractable pain."1.31[Gabapentin in the treatment of chronic intractable pain]. ( Gustorff, B; Kress, HG; Nahlik, G; Spacek, A, 2002)
"Gabapentin treatment significantly and reversibly changed the responses, consistent with the attenuation of the abnormal sensory behavior, and the attenuated responses lasted for the duration of the drug effect (up to 6 h)."1.31Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin. ( Hulsebosch, CE; McAdoo, DJ; Perez-Polo, JR; Taylor, CP; Westlund, KN; Xu, GY, 2000)

Research

Studies (145)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (6.21)18.2507
2000's75 (51.72)29.6817
2010's50 (34.48)24.3611
2020's11 (7.59)2.80

Authors

AuthorsStudies
Hong-Ju, Y1
He, L1
Wei-Guo, S1
Nan, Z1
Wei-Xiu, Y1
Zhong-Wei, J1
Jun-Wei, W1
Zheng-Hua, G1
Bo-Hua, Z1
Zhi-Pu, L1
Zhe-Hui, G1
Jiang, L1
Xiong, Y1
Cui, J1
Guilleminault, L1
Demoulin-Alexikova, S1
de Gabory, L1
Bruley des Varannes, S1
Brouquières, D1
Balaguer, M1
Chapron, A1
Grassin Delyle, S1
Poussel, M1
Guibert, N1
Reychler, G1
Trzepizur, W1
Woisard, V1
Crestani, S1
Shen, Y2
Li, W1
Ma, M1
Jiang, W2
Bobenko, AI1
Heller, S1
Schmitt, N1
Cherdtrakulkiat, R1
Lawung, R1
Nabu, S1
Tantimavanich, S1
Sinthupoom, N1
Prachayasittikul, S1
Prachayasittikul, V1
Zhang, B1
Wu, C1
Zhang, Z2
Yan, K1
Li, C2
Li, Y4
Li, L3
Zheng, C1
Xiao, Y1
He, D1
Zhao, F1
Su, JF1
Lun, SM1
Hou, YJ1
Duan, LJ1
Wang, NC1
Shen, FF1
Zhang, YW1
Gao, ZW1
Li, J5
Du, XJ1
Zhou, FY1
Yin, Z1
Zhu, J2
Yan, D1
Lou, H1
Yu, H1
Feng, C1
Wang, Z1
Wang, Y4
Hu, X1
Li, Z2
Hu, D1
Chen, H1
Wu, X1
Duan, Y1
Zhi, D1
Zou, M2
Zhao, Z1
Zhang, X2
Yang, X2
Zhang, J2
Wang, H1
Popović, KJ1
Popović, DJ1
Miljković, D1
Lalošević, D1
Čapo, I1
Popović, JK1
Liu, M1
Song, H2
Xing, Z1
Lu, G1
Chen, D1
Valentini, AM1
Di Pinto, F1
Coletta, S1
Guerra, V1
Armentano, R1
Caruso, ML1
Gong, J1
Wang, N1
Bian, L1
Wang, M2
Ye, M1
Wen, N1
Fu, M1
Fan, W1
Meng, Y1
Dong, G1
Lin, XH1
Liu, HH1
Gao, DM1
Cui, JF1
Ren, ZG1
Chen, RX1
Önal, B1
Özen, D1
Demir, B1
Akkan, AG1
Özyazgan, S1
Payette, G1
Geoffroy, V1
Martineau, C1
Villemur, R1
Jameel, T1
Baig, M1
Gazzaz, ZJ1
Tashkandi, JM1
Al Alhareth, NS1
Khan, SA1
Butt, NS1
Wang, J2
Geng, Y1
Zhang, Y3
Wang, X2
Liu, J2
Basit, A1
Miao, T1
Liu, W1
Yu, ZY1
Wu, L2
Qu, B1
Sun, JX1
Cai, AL1
Xie, LM1
Groeneveld, J1
Ho, SL1
Mackensen, A1
Mohtadi, M1
Laepple, T1
Genovesi, S1
Nava, E1
Bartolucci, C1
Severi, S1
Vincenti, A1
Contaldo, G1
Bigatti, G1
Ciurlino, D1
Bertoli, SV1
Slovak, JE1
Hwang, JK1
Rivera, SM1
Villarino, NF1
Li, S1
Cao, G1
Ling, M1
Ji, J1
Zhao, D1
Sha, Y1
Gao, X1
Liang, C2
Guo, Q1
Zhou, C1
Ma, Z1
Xu, J1
Wang, C1
Zhao, W1
Xia, X1
Jiang, Y1
Peng, J1
Jia, Z1
Li, F1
Chen, X2
Mo, J1
Zhang, S2
Li, X1
Huang, T1
Zhu, Q1
Wang, S1
Ge, RS1
Fortunato, G1
Lin, J2
Agarwal, PK1
Kohen, A1
Singh, P1
Cheatum, CM1
Zhu, D1
Hayman, A1
Kebede, B1
Stewart, I1
Chen, G1
Frew, R1
Guo, X1
Gong, Q1
Borowiec, J1
Han, S1
Zhang, M2
Willis, M1
Kreouzis, T1
Yu, K1
Chirvony, VS1
Sekerbayev, KS1
Pérez-Del-Rey, D1
Martínez-Pastor, JP1
Palazon, F1
Boix, PP1
Taurbayev, TI1
Sessolo, M1
Bolink, HJ1
Lu, M1
Lan, Y1
Xiao, J1
Song, M1
Chen, C1
Huang, Q1
Cao, Y1
Ho, CT1
Qi, B1
Wang, Q1
Zhang, W1
Fang, L1
Xie, CL1
Chen, R1
Yang, S1
Xia, JM1
Zhang, GY1
Chen, CH1
Yang, XW1
Domenech-Ximenos, B1
Garza, MS1
Prat-González, S1
Sepúlveda-Martínez, Á1
Crispi, F1
Perea, RJ1
Garcia-Alvarez, A1
Sitges, M1
Kalumpha, M1
Guyo, U1
Zinyama, NP1
Vakira, FM1
Nyamunda, BC1
Varga, M1
Drácz, L1
Kolbenheyer, E1
Varga, F1
Patai, ÁV1
Solymosi, N1
Patai, Á1
Kiss, J1
Gaál, V1
Nyul, Z1
Mosdósi, B1
Valdez, M1
Moosavi, L1
Heidari, A1
Novakovic-Agopian, T1
Kornblith, E1
Abrams, G1
McQuaid, JR1
Posecion, L1
Burciaga, J1
D'Esposito, M1
Chen, AJW1
Samy El Gendy, NM1
Wesolowska, P1
Georg, D1
Lechner, W1
Kazantsev, P1
Bokulic, T1
Tedgren, AC1
Adolfsson, E1
Campos, AM1
Alves, VGL1
Suming, L1
Hao, W1
Ekendahl, D1
Koniarova, I1
Bulski, W1
Chelminski, K1
Samper, JLA1
Vinatha, SP1
Rakshit, S1
Siri, S1
Tomsejm, M1
Tenhunen, M1
Povall, J1
Kry, SF1
Followill, DS1
Thwaites, DI1
Izewska, J1
Kang, JH1
Yoon, Y1
Song, J1
Van de Winckel, A1
Gauthier, L1
Chao, CT1
Lee, YH1
Li, CM1
Han, DS1
Huang, JW1
Huang, KC1
Ni, L1
Güttinger, R1
Triana, CA1
Spingler, B1
Baldridge, KK1
Patzke, GR1
Shen, X1
Wang, B1
Xie, S1
Deng, W1
Wu, D1
Zhang, Q1
Voskamp, BJ1
Peelen, MJCS1
Ravelli, ACJ1
van der Lee, R1
Mol, BWJ1
Pajkrt, E1
Ganzevoort, W1
Kazemier, BM1
Tibrewala, R1
Bahroos, E1
Mehrabian, H1
Foreman, SC1
Link, TM1
Pedoia, V1
Majumdar, S1
Jablonski, CL1
Leonard, C1
Salo, P1
Krawetz, RJ1
Yoon, N1
Hong, SN1
Cho, JG1
Jeong, HK1
Lee, KH1
Park, HW1
Barman, S1
Konai, MM1
Samaddar, S1
Haldar, J1
Mohamed, HSH1
Li, CF1
Hu, ZY1
Deng, Z1
Chen, LH1
Su, BL1
Chu, K1
Liu, YP1
Li, YB1
Zhang, H1
Xu, C1
Zou, Z1
Wu, Z1
Xia, Y1
Zhao, P1
Wang, HT1
de Biase, S1
Pellitteri, G1
Gigli, GL1
Valente, M1
Young, JM1
Schoonover, MJ1
Kembel, SL1
Taylor, JD1
Bauck, AG1
Gilliam, LL1
Lee, MY1
Taliercio, RM1
Adessa, M2
Milstein, C1
Bryson, PC2
Song, WJ1
Chung, KF1
Gill, AS1
Virani, FR1
Hwang, JC1
Wilson, MD1
Beliveau, AM1
Strong, EB1
Steele, TO1
Visca, D1
Beghè, B1
Fabbri, LM1
Papi, A1
Spanevello, A1
Russell, M1
Zare, M1
Ahmad, N1
Subhan, F1
Islam, NU1
Shahid, M1
Ullah, N1
Ullah, R1
Akbar, S1
Amin, MU1
Khurram, M1
Ullah, I1
Sewell, RDE1
Lee, HG1
Grossman, SK1
Valdes-Rodriguez, R1
Berenato, F1
Korbutov, J1
Chan, YH1
Lavery, MJ1
Yosipovitch, G2
Wiffen, PJ4
Derry, S3
Bell, RF1
Rice, AS2
Tölle, TR1
Phillips, T1
Moore, RA4
Espinosa-Juárez, JV1
Jaramillo-Morales, OA1
López-Muñoz, FJ1
Kohse, EK1
Hollmann, MW1
Bardenheuer, HJ1
Kessler, J1
Giliberto, JP2
Dibildox, D1
Merati, A1
Rayner, HC1
Larkina, M1
Graham-Brown, M1
van der Veer, SN1
Ecder, T1
Hasegawa, T1
Kleophas, W1
Bieber, BA1
Tentori, F1
Robinson, BM1
Pisoni, RL1
Miao, J1
Aboagye, DE1
Chulpayev, B1
Liu, L1
Ishkanian, G1
Kolanuvada, B1
Alaie, D1
Petrillo, RL1
Vincent, K1
Baranowski, A1
Bhattacharya, S1
Birch, J1
Cheong, Y1
Cregg, R1
Daniels, J1
Hewitt, CA1
Macfarlane, GJ1
Middleton, L1
Szubert, W1
Tracey, I1
Williams, ACC1
Horne, AW1
Bowen, AJ1
Nowacki, AS1
Contrera, K1
Trask, D1
Kaltenbach, J1
Milstein, CF1
Benninger, MS1
Taliercio, R1
Pereira, MP1
Basta, S1
Moore, J1
Ständer, S1
Reszke, R1
Szepietowski, JC1
Kouwenhoven, TA1
van de Kerkhof, PCM1
Kamsteeg, M1
Dong, R1
Xu, X1
Yu, L1
Ding, H1
Pan, J1
Yu, Y1
Shi, C1
Chen, Q1
Lv, H1
Qiu, Z1
Bernhard, JD1
Fostini, AC1
Girolomoni, G1
Tessari, G1
Toelle, T1
Parker, L1
Huelin, R1
Khankhel, Z1
Wasiak, R1
Mould, J1
Wu, CH1
Gunasekara, K1
Hull, JH1
Bikov, A1
Morris, AJ1
Usmani, OS1
Ryan, NM2
Inkpen, H1
Gibson, PG3
Vertigan, AE2
Nakazato-Imasato, E1
Kurebayashi, Y1
Bonnet, U1
Ossowski, A1
Schubert, M1
Gall, H1
Steinkamp, I1
Richter, LE1
Khalil-Boutros, Y1
Nefedev, A1
Kuhlmann, R1
Nascimento-Alves, P1
Fernandes-Silva, H1
Aragão-Homem, C1
Geraldes, R1
Fonseca, AC1
Robertson, KL1
Marshman, LA1
Matsuda, KM1
Sharma, D1
Schonfeld, AR1
Kwatra, SG1
Ward, RE1
Veerula, VL1
Ezra, N1
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Misono, S2
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Freitas, MF1
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Chacur, M1
Forde, G2
Stanos, S1
Levy, BS1
Apgar, BS1
Yamamoto, T1
Fürst, Z1
Chiechio, S1
Zammataro, M1
Caraci, F1
Rampello, L1
Copani, A1
Sabato, AF2
Nicoletti, F1
Sen, H3
Sizlan, A2
Yanarateş, O2
Senol, MG1
Inangil, G1
Sücüllü, I1
Ozkan, S2
Dağli, G2
Gatti, A1
Carucci, A1
Bertini, L1
Mammucari, M1
Occhioni, R1
Clarke, H1
Pereira, S1
Kennedy, D1
Andrion, J1
Mitsakakis, N1
Gollish, J1
Katz, J1
Kay, J1
Jensen, TS1
Finnerup, NB1
Emirkadi, H1
Turan, A2
Yildirim, K1
Deniz, O1
Gureser, G1
Karatay, S1
Ugur, M1
Erdal, A1
Senel, K1
Morris-Stiff, G1
Lewis, MH1
Strauss, AC1
Dimitrakov, JD1
Greene, SM1
Simpson, CB1
Flatters, SJ1
D'Amico, D1
Amr, YM1
Yousef, AA1
Bar Ad, V1
Heidelbaugh, JJ1
Llanes, M1
Weadock, WJ1
Millecamps, M1
Tajerian, M1
Sage, EH1
Stone, LS1
Tsukumo, Y1
Matsumoto, Y1
Miura, H1
Yano, H1
Manabe, H1
Ucak, A1
Onan, B1
Selcuk, I1
Yilmaz, AT1
McQuay, HJ2
Hey, M1
Wilson, I1
Johnson, MI1
Obata, H2
Ogino, Y1
Hoekstra, CE1
Rynja, SP1
van Zanten, GA1
Rovers, MM1
Lantos, PM1
Gunduz, O1
Oltulu, C1
Guven, R1
Buldum, D1
Ulugol, A1
Lua, J1
Bellamy, CO1
Whitworth, C1
Dhaun, N1
Birring, SS1
Laughlin, TM1
Tram, KV1
Wilcox, GL1
Birnbaum, AK1
Surges, R1
Feuerstein, TJ1
Fassoulaki, A2
Patris, K1
Sarantopoulos, C2
Hogan, Q1
Bortalanza, LB1
Ferreira, J1
Hess, SC1
Delle Monache, F1
Yunes, RA1
Calixto, JB1
Haller, H1
Leblhuber, F1
Trenkler, J1
Schmidhammer, R1
Oefelein, MG1
Bayazit, Y1
Lockwood, PA1
Cook, JA1
Ewy, WE1
Mandema, JW1
Spira, PJ1
Beran, RG1
von Orelli, F1
White, WT1
Patel, N1
Drass, M1
Nalamachu, S1
Nicholson, BD1
Lotery, HE1
McClure, N1
Galask, RP1
Stahl, SM1
Baldassano, CF1
Ballas, CA1
O'Reardon, JP1
Urban, MO1
Ren, K1
Park, KT1
Campbell, B1
Anker, N1
Stearns, B1
Aiyar, J1
Belley, M1
Cohen, C1
Bristow, L1
Lauder, GR1
White, MC1
Heartsill, LG1
Brown, TM1
Wiffen, P1
Collins, S1
McQuay, H1
Carroll, D1
Jadad, A1
Moore, A1
Edwards, JE1
Weissenbacher, S1
Ring, J1
Hofmann, H1
Coderre, TJ1
Kumar, N1
Lefebvre, CD1
Yu, JS1
Triga, A1
Melemeni, A1
Sator-Katzenschlager, SM1
Scharbert, G1
Kress, HG2
Frickey, N1
Ellend, A1
Gleiss, A1
Kozek-Langenecker, SA1
Persaud, R1
Frosh, A1
Son, BC1
Lee, SW1
Choi, ES1
Sung, JH1
Hong, JT1
Mintz, S2
Lee, JK2
Kehlet, H1
Cohen, SP1
Sireci, A1
Wu, CL1
Larkin, TM1
Williams, KA1
Hurley, RW1
Bichuetti, DB1
Yamaoka, WY1
Bastos, JR1
Carvalho, Dde S1
Kimos, P1
Biggs, C1
Mah, J1
Heo, G1
Rashiq, S1
Thie, NM1
Major, PW1
Bergasa, NV1
McGee, M1
Ginsburg, IH1
Engler, D1
Pawlik, MT1
Ittner, KP1
Vadalouca, A1
Siafaka, I1
Argyra, E1
Vrachnou, E1
Moka, E1
Hauer, JM1
Wical, BS1
Charnas, L1
Manenti, L1
Vaglio, A1
Jatzko, A1
Stegmeier-Petroianu, A3
Petroianu, GA1
Solak, O2
Metin, M1
Esme, H1
Yaman, M1
Pekcolaklar, A1
Gurses, A1
Kavuncu, V1
Sinclair, AM1
Miller, B1
Lee, LK1
Petroianu, G3
Kong, VK1
Irwin, MG1
Hayashida, K1
Schuchmann, JA1
Browne, BA1
Ketz, AK1
Rudick, CN1
Schaeffer, AJ1
Thumbikat, P1
Benbouzid, M1
Choucair-Jaafar, N1
Yalcin, I1
Waltisperger, E1
Muller, A1
Freund-Mercier, MJ1
Barrot, M1
Bras, M1
Haslam, C1
Nurmikko, T1
Hunter, JC1
Gogas, KR1
Hedley, LR1
Jacobson, LO1
Kassotakis, L1
Thompson, J1
Fontana, DJ1
Nicolodi, M1
Del Bianco, PL1
Sicuteri, F1
García-Albea, E1
Hein, G2
Petroianu, A1
Bergler, W2
Rüfer, R2
Langan, Y1
Duncan, JS1
Sander, JW3
Hansen, HC1
Wong, IC2
Chadwick, DW1
Fenwick, PB1
Mawer, GE1
Ben-David, B1
Friedman, M1
Moretti, R1
Torre, P1
Antonello, RM1
Nasuelli, D1
Cazzato, G1
Kapadia, NP1
Harden, N1
Fragoso, YD1
Carrazana, EJ1
Lhatoo, SD1
Polizzi, G1
Hulsebosch, CE2
Xu, GY1
Perez-Polo, JR1
Westlund, KN1
Taylor, CP1
McAdoo, DJ1
Mills, CD1
Grady, JJ1
Gustorff, B1
Nahlik, G1
Spacek, A1
To, TP1
Lim, TC1
Hill, ST1
Frauman, AG1
Cooper, N1
Kirsa, SW1
Brown, DJ1
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Tarayre, JP1
Koek, W1
Ribet, JP1
Colpaert, FC1

Clinical Trials (26)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
GABA-WHY Study: Deprescription of Gabapentinoids in Medical Inpatients[NCT04855578]160 participants (Actual)Interventional2021-05-28Completed
The Treatment Effect of Chinese Medicine Formula on Uremic Pruritus[NCT04650750]Early Phase 160 participants (Anticipated)Interventional2020-12-01Not yet recruiting
Effectiveness of Sertraline in Alleviating Uremic Pruritis in Hemodialysis Patients[NCT05341843]Phase 260 participants (Actual)Interventional2022-05-01Completed
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain: A Multicenter Prospective Study[NCT04798573]10,000 participants (Anticipated)Observational2012-08-03Active, not recruiting
Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543]90 participants (Actual)Interventional2014-06-30Completed
The Effect of Intravenous Infusions of Lidocaine and Magnesium Versus Lidocaine and Ketamine Versus Lidocaine Alone on Recovery Profile and Postoperative Pain After Elective Gynecological Surgery[NCT04622904]90 participants (Anticipated)Interventional2020-11-14Recruiting
Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia[NCT03066739]Phase 2105 participants (Anticipated)Interventional2023-02-25Recruiting
Diagnostic Challenges in IC (and Male CPPS)[NCT00672087]1,000 participants (Anticipated)Observational2003-09-30Completed
The Effect of Lidocaine to Prevent the Development of Chronic Post-Surgical Pain[NCT01619852]148 participants (Actual)Interventional2012-06-30Completed
Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients[NCT03847311]Phase 240 participants (Anticipated)Interventional2021-05-03Recruiting
Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903]Phase 477 participants (Actual)Interventional2018-05-15Completed
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis[NCT05603702]Phase 124 participants (Anticipated)Interventional2023-03-17Recruiting
Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187]8 participants (Actual)Interventional2009-11-30Terminated (stopped due to PI left institution)
Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology[NCT01403168]28 participants (Actual)Interventional2011-04-30Terminated (stopped due to Recruitment difficulties)
Randomized Controlled Pilot Trial of Adjunct Group Acupuncture vs Usual Care Among Patients With Painful Diabetic Neuropathy[NCT02104466]40 participants (Actual)Interventional2015-03-31Completed
Radiofrequency Thoracic Sympathectomy for Chronic Postmastectomy Pain; Randomized Placebo Controlled Study[NCT03494426]70 participants (Actual)Interventional2018-04-01Completed
Erenumab as a Therapeutic Approach for the Management of Painful Chronic Temporomandibular Disorders (TMD)[NCT05162027]Phase 25 participants (Actual)Interventional2022-04-01Terminated (stopped due to Low enrollment rate)
Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain[NCT02339662]Phase 450 participants (Anticipated)Interventional2015-02-28Recruiting
Study of Gabapentin for the Pruritus of Cholestasis[NCT00058890]Phase 315 participants (Actual)Interventional2000-11-30Completed
A Phase II, Randomized, Placebo-controlled, Double Blind, Cross-over, Study of the Effects of Gabapentin on Chronic Irritability in Neurologically Impaired Children[NCT01675960]Phase 22 participants (Actual)Interventional2012-04-30Terminated (stopped due to unable to enroll)
The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair[NCT02419443]Phase 4100 participants (Anticipated)Interventional2011-08-31Active, not recruiting
Effect of Preoperative Pregabalin on Propofol Induction Dose[NCT01158859]Phase 450 participants (Anticipated)Interventional2010-04-30Completed
The Effect of Gabapentin on Acute Pain and PONV in Bariatric Surgical Patients[NCT00886236]62 participants (Actual)Interventional2008-02-29Completed
Comparison of Oral Lamotrigine Versus Pregabalin for Control of Acute and Chronic Pain Following Modified Radical Mastectomy: Controlled Double-blind Study[NCT03419949]0 participants Expanded AccessAvailable
Phase III Study of the Use of Gabapentin and Osteopathic Manipulative Medicine to Treat Fibromyalgia[NCT01107574]Phase 341 participants (Actual)Interventional2004-04-30Completed
An Open Prospective Randomised Long-Term Effectiveness Study, Comparing Best Medical Practice With or Without Adjunctive VNS Therapy in Patients 16 Years and Older With Pharmaco-resistant Partial Epilepsy[NCT00522418]Phase 4122 participants (Actual)Interventional2006-02-28Terminated (stopped due to Insufficient enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Chronic Persistent Pain 3 Months After Surgery as Determined by Character Severity (Yes/no).

The participants development of chronic persistent pain 3 months after surgery as determined by character severity (yes/no). (NCT01619852)
Timeframe: 3 months

Interventionparticipants (Number)
Group L2
.9% Normal Saline Placebo6

Opioid Consumption

The amount of opioid analgesics consumed was converted to an equivalent dose of intravenous morphine. (NCT01619852)
Timeframe: 24 hours

Interventionequivalent dose of intravenous morphine (Median)
Group L34
.9% Normal Saline Placebo39

Postoperative Pain

Postoperative pain within the first 24 hours. Area under the numeric rating scale for pain versus time curve during the first 24 hours after surgery (score * hr). Numeric rating scale for pain on a scale of 0-10 (0 is no pain and 10 is high pain) versus time curve during the first 24 hours ( score * hr). The pain scores were collected upon arrival to recovery area, 30 minutes, 1 hour and every 6 hours up to 24 hours following the procedure. Minimum score is 60, Maximum score is 170. A higher value indicates more pain. (NCT01619852)
Timeframe: 24 hours

Interventionscore on a scale (Median)
Group L116
.9% Normal Saline Placebo119

Quality of Recovery

Quality of recovery (QoR-40 instrument) is a 40-item questionnaire that provides a global score and sub-scores across five dimensions: patient support, comfort, emotions, physical independence, and pain. Score range: 40 to 200. A score of 40 demonstrates poor recovery and a maximum score of 200 represents good recovery. The higher the score the better recovery after surgery. (NCT01619852)
Timeframe: 24 hours post operative

Interventionunits on a scale (Median)
Lidocaine (Group L)158
.9% Normal Saline Placebo169

Post-surgical Persistent Pain Using Validated Questionnaires (S-LANNS Questionnaire, McGill Questionnaire, Brief Pain Inventory) to Assess Pain Qualities in Accordance With IMMPACT Recommendations.

The development of chronic pain 3 months after surgery determined by the Leads Assessment of Neuropathic Symptoms and Signs (LANSS) scale, a valid 7-item tool for identifying patients whose pain is dominated by neuropathic mechanisms. Each item is a binary response (yes or no) to the presence of symptoms (5 items) or clinical signs (2 items), range 0-24 points. A score ≥ 12, neuropathic mechanisms are likely to be contributing to the patient's pain. A score < 12 is unlikely to be contributing. McGill questionnaire (Sensory domain) - 11 descriptors rated on an intensity scale as 0=none, 1=mild, 2=moderate, 3=severe. The higher the score, greater the pain (range 0-33). McGill questionnaire (Motivational-affective) 4 affect descriptors rated on an intensity scale as 0=none, 1=mild, 2=moderate, 3=severe.The higher the score the greater the pain (range 0-12) Brief pain inventory - pain severity (0, no pain, 10 excruciating pain); Greater the score; greater the pain (range 0-10). (NCT01619852)
Timeframe: 3 months

,
Interventionunits on a scale (Median)
S-LANNSMcGill Questionaire-Sensory DiscrimationMcGill Questionaire-Motivational-affectiveBrief Pain Inventory
.9% Normal Saline Placebo3301
Group L3401

"VAS Score 1: How Much Pain do You Feel in Your Operative Site When Resting?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)

Interventionscore on 10-point scale (Mean)
Standard of Care2.26
Postoperative Gabapentin Regimen2.46

"VAS Score 2: How Much Pain do You Feel in Your Operative Site When Moving?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care3.84
Postoperative Gabapentin Regimen3.54

"VAS Score 3: How Well Are You Sleeping?"

Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care5.73
Postoperative Gabapentin Regimen6.38

"VAS Score 4: How Bad is Your Nausea?"

Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care0.36
Postoperative Gabapentin Regimen0.17

"VAS Score 5: How Satisfied Are You With Your Pain Management?"

Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care7.83
Postoperative Gabapentin Regimen8.48

Days Taking Opioids

Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventiondays (Mean)
Standard of Care14.8
Postoperative Gabapentin Regimen18.7

Opioid Consumption

Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).

Interventionmorphine equivalents (Mean)
Standard of Care287.0
Postoperative Gabapentin Regimen281.1

Evaluate Incidence of Respiratory Depression as Evidenced by Pulse Oximetry Data

(NCT00886236)
Timeframe: 48 hours

Intervention% oxygen saturation (Mean)
1 Preoperative Gabapentin Liquid93
2 Preoperative and Postoperative Gabapentin Liquid94
3 Preoperative and Postoperative Placebo Liquid95

Evaluate the Amount of Diluadid Given Postoperatively

The amount of intraoperative and postoperative opioids used will be collected and analyzed for the three different arms. (NCT00886236)
Timeframe: 120 hours

Interventionml (Mean)
1 Preoperative Gabapentin Liquid11.035
2 Preoperative and Postoperative Gabapentin Liquid8.7
3 Preoperative and Postoperative Placebo Liquid12.4

Number of Participants Who Experience Incidence of Postoperative Nausea.

(NCT00886236)
Timeframe: 120 hours

InterventionParticipants (Count of Participants)
1 Preoperative Gabapentin Liquid12
2 Preoperative and Postoperative Gabapentin Liquid11
3 Preoperative and Postoperative Placebo Liquid12

Change From Baseline in Adverse Event Profile (AEP) Score

Adverse Events Profile (AEP) is a 19-item scale used as a systematic measure of adverse effects from antiepileptic drugs (AEDs). Scores range from 19-76; higher scores indicate high prevelance and severity of adverse events. (NCT00522418)
Timeframe: Mean change from baseline AEP Score at 12 months

InterventionUnits on a scale (Mean)
VNS Therapy-6.0
Best Medical Practice-3.2

Change From Baseline in Center for Epidemiologic Studies Depression Scale (CES-D) Score

The Center for Epidemiologic Studies Depression Scale (CES-D) includes 20 items comprising six scales reflecting major dimensions of depression: depressed mood, feelings of guilt and worthlessness, feelings of helplessness and hopelessness, psychomotor retardation, loss of appetite, and sleep disturbance. Possible range of scores is 0 to 60, higher scores indicate more depressive symptoms. (NCT00522418)
Timeframe: Mean change from baseline CES-D Score at 12 months

InterventionUnits on a Scale (Mean)
VNS Therapy-2.2
Best Medical Practice0.5

Change From Baseline in Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) Score

The Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) is a 6-item questionnaire validated to screen for depression in people with epilepsy. Scores range from 6 to 24, with higher scores indicating more depressive symptoms. (NCT00522418)
Timeframe: Mean change from baseline NDDI-E Score at 12 months

InterventionUnits on a Scale (Mean)
VNS Therapy-1.0
Best Medical Practice-0.2

Changes in Anti-epileptic Drugs (AEDs)

Change from baseline in number of AED medications by visit (NCT00522418)
Timeframe: Change from baseline in number of AEDs at 12 months

InterventionNumber of AEDs Taken (Median)
VNS Therapy0
Best Medical Practice0

Mean Change From Beginning of Intervention Clinical Global Impression-Improvement Scale (CGI-I) Score at 12 Months

The Clinical Global Impression scale (CGI-I) is a 7 point scale that requires the clinician to assess how much the patient's illness has improved or worsened relative to a baseline state at the beginning of the intervention Scores range from 1-7: 1, very much improved; 2, much improved; 3, minimally improved; 4, no change; 5, minimally worse; 6, much worse; or 7, very much worse. (NCT00522418)
Timeframe: Mean change from baseline CGI-I Score at 12 months

InterventionUnits on a Scale (Mean)
VNS Therapy-0.8
Best Medical Practice-0.3

Mean Percent Change in Seizure Frequency

Percent change in total seizuires per week from baseline at 12 months (NCT00522418)
Timeframe: Mean percent change from baseline in seizure frequency at 12 months

InterventionPercent Change (Mean)
VNS Therapy-19.1
Best Medical Practice-1.0

Overall Quality of Life in Epilepsy-89 (QOLIE-89) Score in Patients With Baseline & at Least One Post-baseline QOLIE Assessment

QOLIE-89 contains 17 multi-item measures of overall quality of life, emotional well-being, role limitations due to emotional problems, social support, social isolation, energy/fatigue, worry about seizure, medication effects, health discouragement, work/driving/social function, attention/concentration, language, memory, physical function, pain, role limitations due to physical problems, and health perceptions. Range of values 0-100. Higher scores reflect better quality of life; lower ones, worse quality of life. (NCT00522418)
Timeframe: Mean change from baseline QOLIE-89 Overall Score at 12 months

Interventionunits on a scale (Mean)
VNS Therapy5.5
Best Medical Practice1.2

Response Rate

Response Rate is defined as the percent of participants who are responders. A Responder is defined as participants with a reduction of at least 50% or 75% in seizure frequency from baseline to the seizure count evaluation period. (NCT00522418)
Timeframe: Number of Responders at 12 Months

Interventionparticipants (Number)
VNS Therapy10
Best Medical Practice7

Change From Baseline in QOLIE-89 Measures: Subgroup Analysis of Population With Baseline Adverse Event Profile Score < 40

QOLIE-89 contains 17 multi-item measures of overall quality of life. Range of values 0-100. Higher scores reflect better quality of life; lower ones, worse quality of life. Adverse Events Profile (AEP) is a 19-item scale used as a systematic measure of adverse effects from antiepileptic drugs (AEDs). Scores range from 19-76; higher scores indicate high prevelance and severity of adverse events. (NCT00522418)
Timeframe: Change from baseline up to 12 months

Interventionunits on a scale (Least Squares Mean)
VNS TherapyBest Medical Practice
Baseline Adverse Event Profile Score < 403.30.5

Change From Baseline in QOLIE-89 Measures: Subgroup Analysis of Population With Baseline Adverse Event Profile Score >= 40

QOLIE-89 contains 17 multi-item measures of overall quality of life. Range of values 0-100. Higher scores reflect better quality of life; lower ones, worse quality of life. Adverse Events Profile (AEP) is a 19-item scale used as a systematic measure of adverse effects from antiepileptic drugs (AEDs). Scores range from 19-76; higher scores indicate high prevelance and severity of adverse events. (NCT00522418)
Timeframe: Change from baseline up to 12 months

InterventionUnits on a Scale (Least Squares Mean)
VNS TherapyBest Medical Practice
Baseline Adverse Event Profile Score >= 403.30.7

Reviews

46 reviews available for gabapentin and Chronic Disease

ArticleYear
Comparison of the Efficacy and Safety of Duloxetine and Gabapentin in Diabetic Peripheral Neuropathic Pain: A Meta-Analysis.
    Contrast media & molecular imaging, 2022, Volume: 2022

    Topics: Analgesics; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Duloxetine Hydrochlor

2022
Efficacy and Safety of Gabapentin in Improving Sleep Quality of Patients with Sensory Nervous System Diseases: A Meta-Analysis.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:5

    Topics: Chronic Disease; Gabapentin; Humans; Multicenter Studies as Topic; Sleep; Sleep Initiation and Maint

2023
    Proceedings. Mathematical, physical, and engineering sciences, 2019, Volume: 475, Issue:2227

    Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P

2019
Pharmacotherapeutic Options for Chronic Refractory Cough.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:11

    Topics: Analgesics, Opioid; Antitussive Agents; Chronic Disease; Cough; Gabapentin; Humans; Pyrimidines; Qua

2020
Management of chronic refractory cough in adults.
    European journal of internal medicine, 2020, Volume: 81

    Topics: Adult; Asthma; Chronic Disease; Cough; Gabapentin; Humans; Quality of Life

2020
How to assess and relieve that perplexing rashless itch.
    The Journal of family practice, 2020, Volume: 69, Issue:9

    Topics: Antipruritics; Chronic Disease; Diagnosis, Differential; Evidence-Based Medicine; Gabapentin; Humans

2020
Gabapentin for chronic neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2017, 06-09, Volume: 6

    Topics: Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Diabetic Neur

2017
Chronic Hiccups: An Underestimated Problem.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:4

    Topics: Amines; Anesthesiology; Baclofen; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Am

2017
End-Stage Renal Disease Chronic Itch and Its Management.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antipruritics; Chronic Disease; Cyclohexanecarboxylic A

2018
Clinical practice. Chronic pruritus.
    The New England journal of medicine, 2013, Apr-25, Volume: 368, Issue:17

    Topics: Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic A

2013
Prurigo nodularis: an update on etiopathogenesis and therapy.
    The Journal of dermatological treatment, 2013, Volume: 24, Issue:6

    Topics: Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Dermatologic Agents; Epidermis; Female; Gabape

2013
Gabapentin for chronic neuropathic pain and fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2014, Apr-27, Issue:4

    Topics: Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Fibromyalgia;

2014
A systematic review of pharmacoeconomic studies for pregabalin.
    Pain practice : the official journal of World Institute of Pain, 2015, Volume: 15, Issue:1

    Topics: Amines; Analgesics; Anticonvulsants; Chronic Disease; Cost-Benefit Analysis; Cyclohexanecarboxylic A

2015
A review on the efficacy and safety of gabapentin in the treatment of chronic cough.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:1

    Topics: Amines; Antitussive Agents; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A

2015
Gabapentin in chronic cough.
    Pulmonary pharmacology & therapeutics, 2015, Volume: 35

    Topics: Amines; Animals; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagoni

2015
Management of chronic refractory cough.
    BMJ (Clinical research ed.), 2015, Dec-14, Volume: 351

    Topics: Adaptation, Psychological; Amines; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin;

2015
Gabapentin and pregabalin for the treatment of chronic pruritus.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:3

    Topics: Amines; Anti-Anxiety Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma

2016
Are neuromodulating medications effective for the treatment of chronic neurogenic cough?
    The Laryngoscope, 2017, Volume: 127, Issue:5

    Topics: Amines; Amitriptyline; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminob

2017
Practical management strategies for the chronic pain patient.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chro

2007
The complex nature of chronic pelvic pain.
    The Journal of family practice, 2007, Volume: 56, Issue:3 Suppl Di

    Topics: Adult; Amines; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents,

2007
[Mechanisms of the development of neuropathic pain and its treatment].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2008, Volume: 77, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Calcium Channel Block

2008
[Central and peripheral mechanisms in antinociception: current and future perspectives].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:3

    Topics: Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocycl

2008
Pregabalin in the treatment of chronic pain: an overview.
    Clinical drug investigation, 2009, Volume: 29, Issue:3

    Topics: Amines; Analgesics, Non-Narcotic; Animals; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic

2009
New treatments for chronic prostatitis/chronic pelvic pain syndrome.
    Nature reviews. Urology, 2010, Volume: 7, Issue:3

    Topics: Amines; Chronic Disease; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Gabapentin; gamm

2010
Evidence for sensory neuropathy and pharmacologic management.
    Otolaryngologic clinics of North America, 2010, Volume: 43, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amines; Amitriptyline; Anticonvulsants; Chronic Disease; Cough; Cycloh

2010
Gabapentin for the treatment of cancer-related pain syndromes.
    Reviews on recent clinical trials, 2010, Volume: 5, Issue:3

    Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci

2010
An algorithm for the treatment of chronic testicular pain.
    The Journal of family practice, 2010, Volume: 59, Issue:6

    Topics: Algorithms; Amines; Analgesics; Anesthetics; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive

2010
Gabapentin for chronic neuropathic pain and fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Am

2011
[Molecular mechanisms and clinical pharmacology of chronic pain].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59 Suppl

    Topics: Amines; Animals; Anterior Horn Cells; Antidepressive Agents; Brain; Chronic Disease; Cyclohexanecarb

2010
Anticonvulsants for tinnitus.
    The Cochrane database of systematic reviews, 2011, Jul-06, Issue:7

    Topics: Administration, Oral; Amines; Anticonvulsants; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic

2011
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013, Volume: 148, Issue:3

    Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; ga

2013
Mode of action of gabapentin in chronic neuropathic pain syndromes. A short review about its cellular mechanisms in nociceptive neurotransmission.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:8

    Topics: Acetates; Amines; Animals; Biogenic Monoamines; Calcium Channels; Chronic Disease; Cyclohexanecarbox

2002
[Nonorganic pain -- only psychogenic?].
    Praxis, 2003, Nov-26, Volume: 92, Issue:48

    Topics: Acetates; Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Back Pain; Chronic Dise

2003
Diagnosis and management of neuropathic pain: a balanced approach to treatment.
    Journal of the American Academy of Nurse Practitioners, 2003, Volume: 15, Issue:12 Suppl

    Topics: Acetates; Amines; Antidepressive Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; g

2003
Rethinking the treatment paradigm for bipolar depression: the importance of long-term management.
    CNS spectrums, 2004, Volume: 9, Issue:9 Suppl 9

    Topics: Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Ch

2004
Anticonvulsant drugs for acute and chronic pain.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Acute Disease; Amines; Anticonvulsants; Chronic Disease; Controlled Clinical Trials as Topic; Cycloh

2005
Gabapentin for acute and chronic pain.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Acute Disease; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Ga

2005
Bilateral SUNCT syndrome associated to chronic maxillary sinus disease.
    Arquivos de neuro-psiquiatria, 2006, Volume: 64, Issue:2B

    Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Aci

2006
Therapeutic management of chronic neuropathic pain: an examination of pharmacologic treatment.
    Annals of the New York Academy of Sciences, 2006, Volume: 1088

    Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Chronic Disease; Cyclohexanecarboxylic Acids;

2006
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
    The Journal of family practice, 2007, Volume: 56, Issue:2 Suppl Pa

    Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis;

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
Gabapentin: a multimodal perioperative drug?
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanec

2007
[Alpha2-adrenergic receptors in the dorsal horn of the spinal cord--their function and the descending inhibitory systems].
    Masui. The Japanese journal of anesthesiology, 2007, Volume: 56 Suppl

    Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; Animals; Brain-Derived Neur

2007
Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature.
    American journal of physical medicine & rehabilitation, 2007, Volume: 86, Issue:12

    Topics: Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Cerebral Infarction; Chlorpromazine; Chronic Dis

2007
Pain management in the traumatic amputee.
    Critical care nursing clinics of North America, 2008, Volume: 20, Issue:1

    Topics: Acute Disease; Afghanistan; Amines; Amputation, Traumatic; Analgesia; Analgesics; Benchmarking; Caus

2008
[Psychopharmacotherapy in psychiatric comorbidities among patients with chronic pain].
    L'Encephale, 2007, Volume: 33, Issue:Pt 3

    Topics: Amines; Analgesics; Anticonvulsants; Bupropion; Chronic Disease; Cyclohexanecarboxylic Acids; Dopami

2007
Treatment of chronic pain with antiepileptic drugs: a new era.
    Southern medical journal, 1999, Volume: 92, Issue:7

    Topics: Acetates; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapen

1999

Trials

25 trials available for gabapentin and Chronic Disease

ArticleYear
Efficacy of orally administered gabapentin in horses with chronic thoracic limb lameness.
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:2

    Topics: 4-Butyrolactone; Analgesics; Animals; Chronic Disease; Cross-Over Studies; Drug Therapy, Combination

2020
Gabapentin not effective for chronic pelvic pain in women.
    Drug and therapeutics bulletin, 2021, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Analgesics; Chronic Disease; Double-Blind Method; Female; Gabapentin; Humans; Mid

2021
GaPP2, a multicentre randomised controlled trial of the efficacy of gabapentin for the management of chronic pelvic pain in women: study protocol.
    BMJ open, 2018, 01-31, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; D

2018
Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough.
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:6

    Topics: Adult; Analgesics; Baclofen; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Follo

2019
Gabapentin Superadded to a Pre-Existent Regime Containing Amytriptyline for Chronic Sciatica.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Chronic Disease; Cohort Studies;

2016
The effects of gabapentin on acute and chronic pain after inguinal herniorrhaphy.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:9

    Topics: Adult; Amines; Analgesics; Anesthesia, Spinal; Chronic Disease; Cyclohexanecarboxylic Acids; Double-

2009
Adequacy assessment of oxycodone/paracetamol (acetaminophen) in multimodal chronic pain : a prospective observational study.
    Clinical drug investigation, 2009, Volume: 29 Suppl 1

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid;

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
Gabapentin monotherapy in patients with chronic radiculopathy: the efficacy and impact on life quality.
    Journal of back and musculoskeletal rehabilitation, 2009, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Amines; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids;

2009
Evaluation of efficacy of the perioperative administration of Venlafaxine or gabapentin on acute and chronic postmastectomy pain.
    The Clinical journal of pain, 2010, Volume: 26, Issue:5

    Topics: Acute Disease; Adult; Amines; Analgesics; Breast Neoplasms; Chronic Disease; Cyclohexanecarboxylic A

2010
The effects of gabapentin on acute and chronic postoperative pain after coronary artery bypass graft surgery.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:5

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Chronic Pain; Coronary

2011
Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2012, Nov-03, Volume: 380, Issue:9853

    Topics: Adolescent; Adult; Amines; Anticonvulsants; Central Nervous System; Chronic Disease; Cough; Cyclohex

2012
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr

2002
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr

2002
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr

2002
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr

2002
Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebo-controlled study.
    Neurology, 2003, Dec-23, Volume: 61, Issue:12

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Ataxia; Chronic Disease; Cro

2003
Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain.
    Pain medicine (Malden, Mass.), 2003, Volume: 4, Issue:4

    Topics: Acetates; Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Loca

2003
Gabapentin for the symptomatic treatment of chronic neuropathic pain in patients with late-stage lyme borreliosis: a pilot study.
    Dermatology (Basel, Switzerland), 2005, Volume: 211, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Amines; Chronic Disease; Cyclohexanecarboxylic Acids;

2005
Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:5

    Topics: Acute Disease; Adult; Amines; Analgesia; Anesthetics, Local; Breast Neoplasms; Chronic Disease; Cycl

2005
Chronic pelvic pain treated with gabapentin and amitriptyline: a randomized controlled pilot study.
    Wiener klinische Wochenschrift, 2005, Volume: 117, Issue:21-22

    Topics: Adult; Amines; Amitriptyline; Austria; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Combinatio

2005
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
    Pain, 2007, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids

2007
Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:5

    Topics: Adult; Amines; Analgesics; Cholestasis; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind M

2006
Effectiveness of gabapentin in the treatment of chronic post-thoracotomy pain.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2007, Volume: 32, Issue:1

    Topics: Adult; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-A

2007
An audit of the perceived efficacy and tolerability of gabapentin therapy in an out-patient cohort with chronic epilepsy.
    European neurology, 1999, Volume: 41, Issue:2

    Topics: Acetates; Adult; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Cohort Studies; Cyclohex

1999
Treatment of chronic: new perspectives.
    European journal of neurology, 1999, Volume: 6, Issue:5

    Topics: Acetates; Aged; Amines; Cerebral Infarction; Chronic Disease; Cyclohexanecarboxylic Acids; Excitator

1999
Low doses of gabapentin may be helpful in the management of chronic daily headache.
    MedGenMed : Medscape general medicine, 2000, Aug-21, Volume: 2, Issue:3

    Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic

2000

Other Studies

74 other studies available for gabapentin and Chronic Disease

ArticleYear
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
    Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10

    Topics: Amines; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal

2004
[Guidelines for the management of chronic cough in adults].
    Revue des maladies respiratoires, 2023, Volume: 40, Issue:5

    Topics: Adult; Amitriptyline; Chronic Disease; Cough; Gabapentin; Humans; Quality of Life

2023
A cough that won't go away: Evaluation and treatment in 2 patients.
    Cleveland Clinic journal of medicine, 2020, Volume: 87, Issue:2

    Topics: Aged; Analgesics, Opioid; Botulinum Toxins; Chronic Disease; Cognitive Behavioral Therapy; Cough; Di

2020
Preoperative Gabapentin Administration and Its Impact on Postoperative Opioid Requirement and Pain in Sinonasal Surgery.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2021, Volume: 164, Issue:4

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Chronic Disease; Female; Gabapentin; Humans; Male; Midd

2021
A novel gabapentin analogue assuages neuropathic pain response in chronic sciatic nerve constriction model in rats.
    Behavioural brain research, 2021, 05-07, Volume: 405

    Topics: Analgesics; Animals; Behavior, Animal; Chronic Disease; Constriction; Disease Models, Animal; Excita

2021
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy,

2017
Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:6

    Topics: Amines; Analgesics; Animals; Antipsychotic Agents; Chronic Disease; Constriction, Pathologic; Cycloh

2017
Unilateral Laryngoscopic Findings Associated With Response to Gabapentin in Patients With Chronic Cough.
    JAMA otolaryngology-- head & neck surgery, 2017, 11-01, Volume: 143, Issue:11

    Topics: Amines; Calcium Channel Blockers; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Female; Gabap

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Dec-07, Volume: 12, Issue:12

    Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2017
Importance of Regular and Maintenance Therapy Adherence in Neuromyelitis Optica (NMO): Lessons from a Repeating Relapse Case.
    The American journal of case reports, 2018, Jan-11, Volume: 19

    Topics: Amines; Analgesics; Autoantibodies; Biomarkers; Chronic Disease; Cyclohexanecarboxylic Acids; Female

2018
Short- and Long-term Effects of Neuromodulators for Unexplained Chronic Cough.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018, Volume: 159, Issue:3

    Topics: Adult; Aged; Amitriptyline; Chronic Disease; Cohort Studies; Cough; Dose-Response Relationship, Drug

2018
Prurigo nodularis: a physician survey to evaluate current perceptions of its classification, clinical experience and unmet need.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Chronic Disease; Gabapentin; Histamine Antagonists; Huma

2018
Use of Systemic Treatment in Patients with Chronic Pruritus: A Survey of Dermatologists in the Netherlands.
    Acta dermato-venereologica, 2019, Mar-01, Volume: 99, Issue:3

    Topics: Adult; Antidepressive Agents; Antipruritics; Chronic Disease; Dermatologists; Drug Prescriptions; Fe

2019
Gabapentin as a potential treatment for cough syncope.
    Respiratory care, 2015, Volume: 60, Issue:2

    Topics: Amines; Antitussive Agents; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A

2015
Chronic progressive polyarthritis in a domestic shorthair cat.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:6

    Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Buprenorphine; Cat Diseases; Cats;

2015
Pharmacological characteristics of the hind paw weight bearing difference induced by chronic constriction injury of the sciatic nerve in rats.
    Life sciences, 2009, Apr-24, Volume: 84, Issue:17-18

    Topics: Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; G

2009
[On the Differential Diagnosis of Intractable Psychogenic Chronic Cough: Neuropathic Larynx Irritable - Gabapentin's Antitussive Action].
    Fortschritte der Neurologie-Psychiatrie, 2015, Volume: 83, Issue:10

    Topics: Aged; Amines; Avitaminosis; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Depressive Disorder

2015
IV and V cranial nerves dysfunction as initial manifestations of superficial siderosis of the central nervous system.
    Revista de neurologia, 2016, Apr-01, Volume: 62, Issue:7

    Topics: Aged; Amines; Angiography, Digital Subtraction; Atrophy; Central Nervous System Diseases; Cerebellum

2016
Multilevel symmetric neuropathic pruritus (MSNP) presenting as recalcitrant "generalized" pruritus.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:4

    Topics: Age Distribution; Aged; Amines; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Diseas

2016
Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis.
    European journal of pharmacology, 2017, Mar-15, Volume: 799

    Topics: Amines; Animals; Astrocytes; Behavior, Animal; Cell Count; Chronic Disease; Cyclohexanecarboxylic Ac

2017
Challenges of fragmented care in long-term management of pelvic pain.
    The Journal of family practice, 2007, Volume: 56, Issue:3 Suppl Di

    Topics: Acetaminophen; Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Chr

2007
Fibromyalgia: poorly understood; treatments are disappointing.
    Prescrire international, 2009, Volume: 18, Issue:102

    Topics: Acetaminophen; Acupuncture Therapy; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Ant

2009
Neuropathic pain treatment: a further step forward.
    Lancet (London, England), 2009, Oct-10, Volume: 374, Issue:9697

    Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Chronic Disease; Cyclohexanecarboxylic Acids;

2009
Gabapentin (Neurontin) improves pain scores of patients with critical limb ischaemia: an observational study.
    International journal of surgery (London, England), 2010, Volume: 8, Issue:3

    Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Cyclohexanecarboxylic Acids; Female;

2010
Effect of analgesic standards on persistent postoperative pain evoked by skin/muscle incision and retraction (SMIR).
    Neuroscience letters, 2010, Jun-14, Volume: 477, Issue:1

    Topics: Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Dermatologic Surgical Pro

2010
Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2010, Volume: 31 Suppl 1

    Topics: Amines; Analgesics; Chronic Disease; Clonidine; Cyclohexanecarboxylic Acids; Diagnosis, Differential

2010
Behavioral signs of chronic back pain in the SPARC-null mouse.
    Spine, 2011, Jan-15, Volume: 36, Issue:2

    Topics: Age Factors; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Chronic Diseas

2011
Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice.
    Journal of pharmacological sciences, 2011, Volume: 115, Issue:1

    Topics: Amines; Animals; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Ani

2011
Stellate ganglion blockade (SGB) for refractory index finger pain - a case report.
    Annals of physical and rehabilitation medicine, 2011, Volume: 54, Issue:3

    Topics: Abdominal Pain; Accidental Falls; Acetaminophen; Adult; Amines; Autonomic Nerve Block; Chronic Disea

2011
Chronic Lyme disease: the controversies and the science.
    Expert review of anti-infective therapy, 2011, Volume: 9, Issue:7

    Topics: Amines; Analgesics; Anti-Bacterial Agents; Arthritis, Rheumatoid; Borrelia burgdorferi; Chronic Dise

2011
Pharmacological and behavioral characterization of the saphenous chronic constriction injury model of neuropathic pain in rats.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32, Issue:6

    Topics: Amines; Amitriptyline; Analgesics; Animals; Benzoxazines; Chronic Disease; Constriction; Cyclohexane

2011
Quiz Page October 2011: An under-recognized cause of CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011, Volume: 58, Issue:4

    Topics: Acidosis; Amines; Anorexia Nervosa; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Creati

2011
Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: Acetates; Acute Disease; Adrenergic alpha-Agonists; Amines; Analgesics, Non-Narcotic; Analgesics, Op

2002
Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: Acetates; Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Freund'

2002
Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:9

    Topics: Acetates; Amines; Amitriptyline; Analgesics; Arm; Carbamazepine; Central Cord Syndrome; Cervical Ver

2003
Chronic pain syndrome after laparoscopic radical nephrectomy.
    The Journal of urology, 2003, Volume: 170, Issue:5

    Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Carcinoma, Renal Cell; Carcinoma, Transition

2003
[Unclear chronic aches. Often depression plays a part therein].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Age

2003
The use of clinical trial simulation to support dose selection: application to development of a new treatment for chronic neuropathic pain.
    Pharmaceutical research, 2003, Volume: 20, Issue:11

    Topics: Acetates; Amines; Analgesics; Chronic Disease; Clinical Trials, Phase II as Topic; Computer Simulati

2003
Vulvodynia.
    Lancet (London, England), 2004, Mar-27, Volume: 363, Issue:9414

    Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Chroni

2004
Gabapentin (Neurontin) for chronic pain.
    The Medical letter on drugs and therapeutics, 2004, Apr-12, Volume: 46, Issue:1180

    Topics: Acetates; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Costs; Drug Interac

2004
Anticonvulsants and the relief of chronic pain: pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; G

2004
Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Benzylamines; Chronic Disease; Cyclohexanecarb

2005
Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:5

    Topics: Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cerebral Palsy; Chi

2005
Use of gabapentin for rest pain in chronic critical limb ischemia.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6

    Topics: Amines; Analgesics; Bed Rest; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminob

2005
Evidence that gabapentin reduces neuropathic pain by inhibiting the spinal release of glutamate.
    Journal of neurochemistry, 2005, Volume: 94, Issue:4

    Topics: Amines; Analgesics; Animals; Aspartic Acid; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory

2005
The aetiology of chronic cough: a review of current theories for the otorhinolaryngologists.
    The Journal of laryngology and otology, 2006, Volume: 120, Issue:2

    Topics: Amines; Anticonvulsants; Chronic Disease; Cough; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids

2006
Motor cortex stimulation for central pain following a traumatic brain injury.
    Pain, 2006, Volume: 123, Issue:1-2

    Topics: Accidental Falls; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Aphasia, Broca; Brain Inju

2006
Gabapentin in the treatment of intractable idiopathic chronic cough: case reports.
    The American journal of medicine, 2006, Volume: 119, Issue:5

    Topics: Adult; Aged; Amines; Calcium Channel Blockers; Chronic Disease; Cough; Cyclohexanecarboxylic Acids;

2006
Perioperative analgesia to prevent chronic postmastectomy pain.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:2

    Topics: Amines; Anesthetics, Local; Breast Neoplasms; Chronic Disease; Cyclohexanecarboxylic Acids; Female;

2006
Pulsed radiofrequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed radiofrequency of the intercostal nerves in the treatment of chronic postsurgical thoracic pain.
    Pain physician, 2006, Volume: 9, Issue:3

    Topics: Adult; Amines; Analgesics; Anticonvulsants; Carbamazepine; Catheter Ablation; Chronic Disease; Cyclo

2006
[Post-operative pain therapy of a chronic pain patient].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2006, Volume: 41, Issue:11

    Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Co

2006
Chronic cough as a sign of laryngeal sensory neuropathy: diagnosis and treatment.
    The Annals of otology, rhinology, and laryngology, 2006, Volume: 115, Issue:11

    Topics: Amines; Chronic Disease; Cough; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Diff

2006
Gabapentin successfully manages chronic unexplained irritability in children with severe neurologic impairment.
    Pediatrics, 2007, Volume: 119, Issue:2

    Topics: Adolescent; Adult; Amines; Analgesics; Child; Child, Preschool; Chronic Disease; Cyclohexanecarboxyl

2007
Gabapentin use in chronic uraemic itch is in line with emerging pathogenetic hypothesis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:12

    Topics: Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; P

2007
Alpha-2-delta ligands for singultus (hiccup) treatment: three case reports.
    Journal of pain and symptom management, 2007, Volume: 33, Issue:6

    Topics: Aged; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabap

2007
Chronic orchialgia: consider gabapentin or nortriptyline before considering surgery.
    International journal of urology : official journal of the Japanese Urological Association, 2007, Volume: 14, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Calcium Channel Blockers; Chronic Disease; Cycloh

2007
[The 10-minute-consultation: chronic singultus].
    MMW Fortschritte der Medizin, 2007, Mar-22, Volume: 149, Issue:12

    Topics: Aged; Amines; Anti-Ulcer Agents; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Diag

2007
Experimental autoimmune prostatitis induces chronic pelvic pain.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:4

    Topics: Amines; Analgesics; Anesthetics, Local; Animals; Autoimmune Diseases; Chronic Disease; Cyclohexaneca

2008
Chronic, but not acute, tricyclic antidepressant treatment alleviates neuropathic allodynia after sciatic nerve cuffing in mice.
    European journal of pain (London, England), 2008, Volume: 12, Issue:8

    Topics: Amines; Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain; Chronic Di

2008
Pharmacological treatment of neuropathic pain in older persons.
    Clinical interventions in aging, 2008, Volume: 3, Issue:1

    Topics: Aged; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Chronic Disease

2008
The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain.
    European journal of pharmacology, 1997, Apr-18, Volume: 324, Issue:2-3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Anticonvulsants; Chronic Disease; Cyclohexanec

1997
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
    International journal of clinical pharmacology research, 1997, Volume: 17, Issue:2-3

    Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagon

1997
[Prophylactic treatment with gabapentin in chronic daily headache resistant to other drugs].
    Revista de neurologia, 1998, Volume: 26, Issue:153

    Topics: Acetates; Adult; Aged; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Resist

1998
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
    Zeitschrift fur Gastroenterologie, 1998, Volume: 36, Issue:7

    Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxyl

1998
The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy.
    Epilepsia, 1999, Volume: 40, Issue:10

    Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Clinical Trials as Topic; Cyclo

1999
Gabapentin therapy for vulvodynia.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:6

    Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic

1999
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
    Journal of clinical gastroenterology, 2000, Volume: 30, Issue:3

    Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Admi

2000
Gabapentin for chronic pain in spinal cord injury: a case report.
    Archives of physical medicine and rehabilitation, 2000, Volume: 81, Issue:10

    Topics: Acetates; Adult; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapenti

2000
Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy.
    Epilepsia, 2000, Volume: 41, Issue:12

    Topics: Acetates; Adolescent; Adult; Age of Onset; Aged; Amines; Anticonvulsants; Chronic Disease; Cyclohexa

2000
Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin.
    Journal of neurotrauma, 2000, Volume: 17, Issue:12

    Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Chronic Disease; Contusions; Cyclohexanecar

2000
Changes in exploratory behavior as a measure of chronic central pain following spinal cord injury.
    Journal of neurotrauma, 2001, Volume: 18, Issue:10

    Topics: Acetates; Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Exploratory Beh

2001
[Gabapentin in the treatment of chronic intractable pain].
    Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1

    Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non

2002
Gabapentin for neuropathic pain following spinal cord injury.
    Spinal cord, 2002, Volume: 40, Issue:6

    Topics: Acetates; Acute Disease; Adolescent; Adult; Aged; Amines; Chronic Disease; Cyclohexanecarboxylic Aci

2002
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:4

    Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Ag

2002