gabapentin has been researched along with Cerebellar Ataxia in 3 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this work was to investigate the efficacy of the GABAergic drug gabapentin in the treatment of the cerebellar signs caused by cortical cerebellar atrophy (CCA)." | 9.11 | Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study. ( Benavente, I; Errea, JM; Gazulla, J; Tordesillas, CJ, 2004) |
| "The aim of this work was to investigate the efficacy of the GABAergic drug gabapentin in the treatment of the cerebellar signs caused by cortical cerebellar atrophy (CCA)." | 5.11 | Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study. ( Benavente, I; Errea, JM; Gazulla, J; Tordesillas, CJ, 2004) |
| " Finally, we consider the link between alpha2delta subunits and disease, both in terms of spontaneous and engineered mouse mutants that show cerebellar ataxia and spike-wave epilepsy, and in terms of neuropathic pain and the mechanism of action of the gabapentinoid drugs - small-molecule ligands of the alpha2delta-1 and alpha2delta-2 subunits." | 4.84 | Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels. ( Davies, A; Dolphin, AC; Douglas, L; Hendrich, J; Van Minh, AT; Wratten, J, 2007) |
| "Gabapentin has been accepted worldwide as a novel antiepileptic drug with a favourable tolerability profile." | 1.30 | Isolated ataxia as an idiosyncratic side-effect under gabapentin. ( Bittermann, HJ; Herrendorf, G; Kurth, C; Steinhoff, BJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gazulla, J | 1 |
| Errea, JM | 1 |
| Benavente, I | 1 |
| Tordesillas, CJ | 1 |
| Davies, A | 1 |
| Hendrich, J | 1 |
| Van Minh, AT | 1 |
| Wratten, J | 1 |
| Douglas, L | 1 |
| Dolphin, AC | 1 |
| Steinhoff, BJ | 1 |
| Herrendorf, G | 1 |
| Bittermann, HJ | 1 |
| Kurth, C | 1 |
1 review available for gabapentin and Cerebellar Ataxia
| Article | Year |
|---|---|
Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebellar Ataxia; Cyclo | 2007 |
1 trial available for gabapentin and Cerebellar Ataxia
| Article | Year |
|---|---|
Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Atrophy; Cerebellar Ataxia; Cerebellar Cortex; Cyclohe | 2004 |
1 other study available for gabapentin and Cerebellar Ataxia
| Article | Year |
|---|---|
Isolated ataxia as an idiosyncratic side-effect under gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cerebellar Ataxia; Cyclohexanecarboxylic Acids; Dose-Respo | 1997 |