Page last updated: 2024-10-27

gabapentin and Cancer-Associated Pain

gabapentin has been researched along with Cancer-Associated Pain in 11 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" The inclusion criteria are adult patients with cancer suffering from neuropathic cancer pain refractory to opioids and gabapentinoids, patients with a Numerical Rating Scale (NRS) pain score of 4 or higher and patients with a total Hospital Anxiety and Depression Scale score of less than 20."9.24Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study. ( Ariyoshi, K; Ishiki, H; Iwase, S; Kawaguchi, T; Kizawa, Y; Koyama, A; Matsuda, Y; Matsuoka, H; Miyaji, T; Morita, T; Yamaguchi, T, 2017)
"Gabapentin has been used as an adjuvant for treatment of cancer pain."9.22The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
"Gabapentinoids are frequently used in the management of cancer pain."8.98A critical appraisal of gabapentinoids for pain in cancer patients. ( Bennett, MI; Jordan, RI; Mulvey, MR, 2018)
"Morphine infusion through Intrathecal Drug Delivery System (IDDS) is widely used to relieve refractory cancer pain."8.02Gabapentin enhances the antinociceptive effect of intrathecal morphine in refractory cancer pain patients. ( Dai, J; Lin, S; Shao, H; Teng, L; Zhang, W; Zhao, L; Zou, H, 2021)
" The inclusion criteria are adult patients with cancer suffering from neuropathic cancer pain refractory to opioids and gabapentinoids, patients with a Numerical Rating Scale (NRS) pain score of 4 or higher and patients with a total Hospital Anxiety and Depression Scale score of less than 20."5.24Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study. ( Ariyoshi, K; Ishiki, H; Iwase, S; Kawaguchi, T; Kizawa, Y; Koyama, A; Matsuda, Y; Matsuoka, H; Miyaji, T; Morita, T; Yamaguchi, T, 2017)
"Gabapentin has been used as an adjuvant for treatment of cancer pain."5.22The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
"Gabapentinoids are frequently used in the management of cancer pain."4.98A critical appraisal of gabapentinoids for pain in cancer patients. ( Bennett, MI; Jordan, RI; Mulvey, MR, 2018)
"Morphine infusion through Intrathecal Drug Delivery System (IDDS) is widely used to relieve refractory cancer pain."4.02Gabapentin enhances the antinociceptive effect of intrathecal morphine in refractory cancer pain patients. ( Dai, J; Lin, S; Shao, H; Teng, L; Zhang, W; Zhao, L; Zou, H, 2021)
"Gabapentinoid use for long-term cancer pain control may be problematic, given unclear mechanisms of action and increased concerns for physical dependence."3.96Use of gabapentinoid medications among US adults with cancer, 2005-2015. ( Choi, SW; Davis, MA; Fauer, AJ; Friese, CR; Wallner, LP, 2020)
"Managing cancer-related pain in patients who are also pregnant compounds the challenge for adequate pain management, as studies have largely excluded this population."3.01Pharmacologic Management of Cancer-Related Pain in Pregnant Patients. ( McGinn, R; Smith, MA; Zerfas, I, 2023)
"Chronic postsurgical pain (CPSP) is an important and well recognized cause of much long-term suffering, which in some cases may be preventable and affects many people living with cancer."2.58Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable. ( Bhaskar, A; Humble, SR; Jayaweera, A; Varela, N, 2018)
"Compared with nociceptive pain, neuropathic pain is a challenging diagnosis to make and successfully treat in children with cancer."1.46Very-Low-Dose Methadone To Treat Refractory Neuropathic Pain in Children with Cancer. ( Bruera, E; Madden, K, 2017)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (63.64)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
Brito, BE1
García, MA1
De Gouveia, YM1
Bolaños, P1
Devis, S1
Bernal, G1
Tortorici-Brito, VA1
Baute, L1
Díaz-Serrano, G1
Tortorici, V1
Zerfas, I1
McGinn, R1
Smith, MA1
Fauer, AJ1
Davis, MA1
Choi, SW1
Wallner, LP1
Friese, CR1
Teng, L1
Dai, J1
Shao, H1
Zhao, L1
Lin, S1
Zhang, W1
Zou, H1
Corona-Ramos, JN1
Déciga-Campos, M1
Romero-Piña, M1
Medina, LA1
Martínez-Racine, I1
Jaramillo-Morales, OA1
García-López, P1
López-Muñoz, FJ1
Madden, K1
Bruera, E1
Matsuoka, H1
Ishiki, H1
Iwase, S1
Koyama, A1
Kawaguchi, T1
Kizawa, Y1
Morita, T1
Matsuda, Y1
Miyaji, T1
Ariyoshi, K1
Yamaguchi, T1
Jordan, RI1
Mulvey, MR1
Bennett, MI1
Humble, SR1
Varela, N1
Jayaweera, A1
Bhaskar, A1
Anghelescu, DL1
Pankayatselvan, V1
Nguyen, R1
Ward, D1
Wu, J1
Wu, H1
Edwards, DD1
Furman, W1
Chen, DL1
Li, YH1
Wang, ZJ1
Zhu, YK1

Reviews

3 reviews available for gabapentin and Cancer-Associated Pain

ArticleYear
Pharmacologic Management of Cancer-Related Pain in Pregnant Patients.
    Drugs, 2023, Volume: 83, Issue:12

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Duloxetine Hydrochloride; Female; Gabapentin; Humans; N

2023
A critical appraisal of gabapentinoids for pain in cancer patients.
    Current opinion in supportive and palliative care, 2018, Volume: 12, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Drug Therapy, Combination; Gabapentin; Humans; Pain; Pa

2018
Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable.
    Current opinion in supportive and palliative care, 2018, Volume: 12, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Chronic Pain; Drug Therapy, Combination; Gabapentin; Ge

2018

Trials

2 trials available for gabapentin and Cancer-Associated Pain

ArticleYear
Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study.
    BMJ open, 2017, Aug-28, Volume: 7, Issue:8

    Topics: Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Cancer Pain; Cyclohexanecarboxylic Acids; Doubl

2017
The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain.
    Medicine, 2016, Volume: 95, Issue:42

    Topics: Adult; Amines; Analgesics; Cancer Pain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Dru

2016

Other Studies

6 other studies available for gabapentin and Cancer-Associated Pain

ArticleYear
Concomitant Antihyperalgesic and Antitumor Effects of Gabapentin in a Murine Cancer Pain Model.
    International journal of molecular sciences, 2021, Sep-07, Volume: 22, Issue:18

    Topics: Analgesics; Animals; Antineoplastic Agents; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; D

2021
Use of gabapentinoid medications among US adults with cancer, 2005-2015.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Cancer Pain; Chronic Pain; Cross-Sectional S

2020
Gabapentin enhances the antinociceptive effect of intrathecal morphine in refractory cancer pain patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:12

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Drug Tolerance; Gabapentin; Humans; Morphine; Neoplasms

2021
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
    Drug development research, 2017, Volume: 78, Issue:5

    Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Su

2017
Very-Low-Dose Methadone To Treat Refractory Neuropathic Pain in Children with Cancer.
    Journal of palliative medicine, 2017, Volume: 20, Issue:11

    Topics: Amines; Analgesics; Analgesics, Opioid; Cancer Pain; Child; Child, Preschool; Chronic Pain; Cyclohex

2017
Bisphosphonate Use in Pediatric Oncology for Pain Management.
    The American journal of hospice & palliative care, 2019, Volume: 36, Issue:2

    Topics: Administration, Oral; Adolescent; Age Factors; Age of Onset; Analgesics, Opioid; Bone Neoplasms; Can

2019