gabapentin has been researched along with Burns in 17 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A retrospective review of charts and pharmacy records of gabapentin and pregabalin dispensed to control pruritus and/or pain was conducted for burn survivors up to 20 years of age." | 7.88 | Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review. ( Amin, A; Kaul, I; Meyer, WJ; Rosenberg, L; Rosenberg, M, 2018) |
| "Compared with that before treatment, the itching degree of patients with light, moderate, and severe itching in placebo group was not relieved after treatment; the itching degree of patients with moderate or severe itching in cetirizine group was alleviated after treatment, but not in patients with light itching; itching degree of all patients in gabapentin group was significantly relieved after treatment." | 7.81 | [Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn]. ( Bing, Z; Qiang, W; Wei, L; Zheng, L, 2015) |
| "During treatment and post-treatment phases, patients receiving Gp had cumulative morphine consumption and a mean daily pain score significantly lower than controls." | 7.74 | Effects of gabapentin on morphine consumption and pain in severely burned patients. ( Cuignet, O; Pirson, J; Soudon, O; Zizi, M, 2007) |
| "We describe the use of gabapentin for the treatment of itching in wound healing in 35 children." | 7.72 | Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study. ( Mendham, JE, 2004) |
| "Gabapentin is an antiepileptic drug which has been successfully used to manage neuropathic pain, and is reporting to be successful in management of all forms of itch." | 6.76 | A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus. ( Ahuja, RB; Gupta, G; Gupta, R; Shrivastava, P, 2011) |
| "Gabapentin has established efficacy in the reduction of burn-induced hyperalgesia and allodynia in animal and human experimental burn models." | 5.35 | Successful use of gabapentin in acute pain management following burn injury: a case series. ( Cramond, T; Gray, P; Williams, B, 2008) |
| "A retrospective review of charts and pharmacy records of gabapentin and pregabalin dispensed to control pruritus and/or pain was conducted for burn survivors up to 20 years of age." | 3.88 | Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review. ( Amin, A; Kaul, I; Meyer, WJ; Rosenberg, L; Rosenberg, M, 2018) |
| "We studied 23 patients with severe pruritus scoring at least 5 on the visual analogue scale (VAS) and refractory to antihistamine and gabapentin administration." | 3.88 | Effect of cold pack therapy for management of burn scar pruritus: A pilot study. ( Cho, YS; Joo, SY; Kim, JB; Seo, CH, 2018) |
| "Compared with that before treatment, the itching degree of patients with light, moderate, and severe itching in placebo group was not relieved after treatment; the itching degree of patients with moderate or severe itching in cetirizine group was alleviated after treatment, but not in patients with light itching; itching degree of all patients in gabapentin group was significantly relieved after treatment." | 3.81 | [Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn]. ( Bing, Z; Qiang, W; Wei, L; Zheng, L, 2015) |
| "During treatment and post-treatment phases, patients receiving Gp had cumulative morphine consumption and a mean daily pain score significantly lower than controls." | 3.74 | Effects of gabapentin on morphine consumption and pain in severely burned patients. ( Cuignet, O; Pirson, J; Soudon, O; Zizi, M, 2007) |
| "We describe the use of gabapentin for the treatment of itching in wound healing in 35 children." | 3.72 | Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study. ( Mendham, JE, 2004) |
| "Gabapentin is an antiepileptic drug which has been successfully used to manage neuropathic pain, and is reporting to be successful in management of all forms of itch." | 2.76 | A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus. ( Ahuja, RB; Gupta, G; Gupta, R; Shrivastava, P, 2011) |
| "Post-burn pruritus is the pruritus that occurs after burn during the rehabilitation and healing process of burn wounds." | 2.66 | Post-Burn Pruritus. ( Chung, BY; Jung, MJ; Kang, SY; Kim, HB; Kim, HO; Kwak, IS; Park, CW, 2020) |
| "Post burn pruritus is a well recognised symptom in almost all burn patients." | 2.48 | Post burn pruritus--a review of current treatment options. ( Gupta, AK; Lamba, S; Paul, MK; Prabha, R; Rao, AL; Zachariah, JR, 2012) |
| "Chronic neuropathic pain (CNP) after burn injury to the hand/upper extremity is relatively common, but not well described in the literature." | 1.62 | Chronic Neuropathic Pain Following Hand Burns: Etiology, Treatment, and Long-Term Outcomes. ( Dellon, AL; Hultman, CS; Klifto, KM; Lifchez, SD; Yesantharao, PS, 2021) |
| "Gabapentin has analgesic efficacy for neuropathic pain and is increasingly used in burn care." | 1.51 | The Effects of Early Neuropathic Pain Control With Gabapentin on Long-Term Chronic Pain and Itch in Burn Patients. ( Carrougher, GJ; Gibran, NS; Kneib, CJ; Mandell, SP; Muffley, LA; Sibbett, SH, 2019) |
| "Gabapentin has established efficacy in the reduction of burn-induced hyperalgesia and allodynia in animal and human experimental burn models." | 1.35 | Successful use of gabapentin in acute pain management following burn injury: a case series. ( Cramond, T; Gray, P; Williams, B, 2008) |
| "Gabapentin is an anticonvulsant that may represent a novel class of drugs, which has novel spinal antihyperalgesic activity." | 1.30 | The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat. ( Jun, JH; Yaksh, TL, 1998) |
| "Secondary hyperalgesia exhibited a tendency toward recovery over time." | 1.30 | Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia. ( Jones, DL; Sorkin, LS, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 5 (29.41) | 2.80 |
| Authors | Studies |
|---|---|
| Chaghazardi, S | 1 |
| Hedari, M | 1 |
| Bazargan-Hejazi, S | 1 |
| Mohammadi, R | 1 |
| Ahmadi, A | 1 |
| Natalwala, I | 1 |
| Kiely, J | 1 |
| Kilshaw, A | 1 |
| McKay, G | 1 |
| Chu, V | 1 |
| Phipps, A | 1 |
| Anwar, MU | 1 |
| Yarwood, J | 1 |
| Sandhu, R | 1 |
| Muthayya, P | 1 |
| Sloan, B | 1 |
| Lennertz, R | 1 |
| Zimmerman, H | 1 |
| McCormick, T | 1 |
| Hetzel, S | 1 |
| Faucher, L | 1 |
| Gibson, A | 1 |
| Chung, BY | 1 |
| Kim, HB | 1 |
| Jung, MJ | 1 |
| Kang, SY | 1 |
| Kwak, IS | 1 |
| Park, CW | 1 |
| Kim, HO | 1 |
| Klifto, KM | 1 |
| Yesantharao, PS | 1 |
| Dellon, AL | 1 |
| Hultman, CS | 1 |
| Lifchez, SD | 1 |
| Kaul, I | 1 |
| Amin, A | 1 |
| Rosenberg, M | 1 |
| Rosenberg, L | 1 |
| Meyer, WJ | 1 |
| Joo, SY | 1 |
| Kim, JB | 1 |
| Cho, YS | 2 |
| Seo, CH | 1 |
| Kneib, CJ | 1 |
| Sibbett, SH | 1 |
| Carrougher, GJ | 1 |
| Muffley, LA | 1 |
| Gibran, NS | 1 |
| Mandell, SP | 1 |
| Zheng, L | 1 |
| Bing, Z | 1 |
| Wei, L | 1 |
| Qiang, W | 1 |
| Ahuja, RB | 1 |
| Gupta, R | 1 |
| Gupta, G | 1 |
| Shrivastava, P | 1 |
| Zachariah, JR | 1 |
| Rao, AL | 1 |
| Prabha, R | 1 |
| Gupta, AK | 1 |
| Paul, MK | 1 |
| Lamba, S | 1 |
| Anand, S | 1 |
| Mendham, JE | 1 |
| Cuignet, O | 1 |
| Pirson, J | 1 |
| Soudon, O | 1 |
| Zizi, M | 1 |
| Gray, P | 1 |
| Williams, B | 1 |
| Cramond, T | 1 |
| Jun, JH | 1 |
| Yaksh, TL | 1 |
| Jones, DL | 1 |
| Sorkin, LS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns[NCT06104540] | 24 participants (Anticipated) | Interventional | 2023-11-01 | Not yet recruiting | |||
| A pRospective, Case-controlled Evaluation of oLIceridine for Moderate or sEVEre Pain in Patients With Acute Burn Injuries. (RELIEVE)[NCT05465226] | Phase 4 | 31 participants (Actual) | Interventional | 2023-04-01 | Completed | ||
| The Effect of Neurontin on Pain Management in the Acutely Burned Patient[NCT01265056] | 53 participants (Actual) | Interventional | 2010-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The sickness inventory profile (SIP) is a behaviorally based measure of health status. Scores range from 0-68 with higher numbers indicating worse outcomes. The study report total SIP score. The higher the score the worse the function. (NCT01265056)
Timeframe: First Clinic Follow Up After Discharge
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 34.9 |
| Gabapentin | 36.0 |
(NCT01265056)
Timeframe: From time of enrollment to 2 weeks after being discharged
| Intervention | morphine equivalents (Mean) |
|---|---|
| Placebo | 7.0 |
| Gabapentin | 6.7 |
The Brief Symptom Inventory 18 (BSI 18) is designed with reliability in mind. The BSI 18 assessment gathers patient-reported data to help measure psychological distress and psychiatric disorders in medical and community populations. As the latest in an integrated series of test instruments that include the SCL-90-R®, BSI® (53 questions), and DPRS® instruments, the BSI 18 test offers a more effective, easy-to-administer tool to help support clinical decision-making and monitor progress throughout treatment. BSI-18 measures three dimensions with 6 questions a piece (somatization , depression , anxiety) and overall psychological distress scores (Global severity index, GSI). Each of the 18 items range from a score of 0-4; total score ranges from 0-72 with higher scores indicating worse function. The GSI score is calculated as the mean of the three subscales. The study reported the GSI score. Higher score is worse. (NCT01265056)
Timeframe: First Clinic Follow Up After Discharge
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 9 |
| Gabapentin | 7.3 |
3 reviews available for gabapentin and Burns
| Article | Year |
|---|---|
Post-Burn Pruritus.
Topics: Animals; Antipsychotic Agents; Burns; Gabapentin; Histamine Antagonists; Humans; Inflammation; Kerat | 2020 |
Post burn pruritus--a review of current treatment options.
Topics: Amines; Analgesics; Burns; Cyclohexanecarboxylic Acids; Emollients; Gabapentin; gamma-Aminobutyric A | 2012 |
Gabapentin for pruritus in palliative care.
Topics: Amines; Analgesics, Opioid; Burns; Cholestasis; Cyclohexanecarboxylic Acids; Dermatologic Agents; Ga | 2013 |
2 trials available for gabapentin and Burns
| Article | Year |
|---|---|
Comparing the Effect of Gabapentin, Ketamine, Dexmedetomidine, and Entonox on Pain Control in Burn Wound Dressing.
Topics: Adult; Analgesics; Bandages; Blood Pressure; Burns; Debridement; Dexmedetomidine; Female; Gabapentin | 2020 |
A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Burns; Cetirizine; Child; Cyclohexanecarboxylic Acids; | 2011 |
12 other studies available for gabapentin and Burns
| Article | Year |
|---|---|
The Pinderfields hospital pain management protocol for enzymatic debridement of burns wounds.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Ane | 2020 |
Perioperative Multimodal Analgesia Reduces Opioid Use Following Skin Grafting in Nonintubated Burn Patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Bandages; | 2020 |
Chronic Neuropathic Pain Following Hand Burns: Etiology, Treatment, and Long-Term Outcomes.
Topics: Burns; Gabapentin; Hand Injuries; Humans; Neuralgia; Pain Management | 2021 |
Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review.
Topics: Adolescent; Analgesics; Burns; Child; Child, Preschool; Female; Gabapentin; Humans; Infant; Male; Ne | 2018 |
Effect of cold pack therapy for management of burn scar pruritus: A pilot study.
Topics: Adult; Burns; Cicatrix; Cryotherapy; Excitatory Amino Acid Antagonists; Female; Gabapentin; Histamin | 2018 |
The Effects of Early Neuropathic Pain Control With Gabapentin on Long-Term Chronic Pain and Itch in Burn Patients.
Topics: Adolescent; Adult; Analgesics; Burns; Female; Gabapentin; Humans; Male; Middle Aged; Neuralgia; Pain | 2019 |
[Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn].
Topics: Amines; Analgesics; Ascorbic Acid; Burns; Cetirizine; Cicatrix; Cyclohexanecarboxylic Acids; Gabapen | 2015 |
Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.
Topics: Adolescent; Amines; Antipruritics; Burns; Child; Child Behavior Disorders; Child, Preschool; Cyclohe | 2004 |
Effects of gabapentin on morphine consumption and pain in severely burned patients.
Topics: Administration, Oral; Amines; Analgesics; Burns; Case-Control Studies; Cyclohexanecarboxylic Acids; | 2007 |
Successful use of gabapentin in acute pain management following burn injury: a case series.
Topics: Adult; Amines; Analgesics; Burns; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyri | 2008 |
The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat.
Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relati | 1998 |
Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relati | 1998 |