Page last updated: 2024-10-27

gabapentin and Brain Infarction

gabapentin has been researched along with Brain Infarction in 3 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin pretreatment (200  mg/kg, intravenously) reduced the infarct volume by 23% after transient focal ischemia in mice."1.37Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations. ( Ayata, C; Eikermann-Haerter, K; Hoffmann, U; Lee, JH; Qin, T, 2011)
"Nonconvulsive seizures (NCSs) after traumatic and ischemic brain injury are often refractory to antiepileptic drug therapy and are associated with a decline in patient outcome."1.32Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. ( Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, MY1
Liu, RF1
Chang, YY1
Hoffmann, U1
Lee, JH1
Qin, T1
Eikermann-Haerter, K1
Ayata, C1
Williams, AJ1
Tortella, FC1
Lu, XM1
Moreton, JE1
Hartings, JA1

Other Studies

3 other studies available for gabapentin and Brain Infarction

ArticleYear
Image Gallery: Trigeminal trophic syndrome: nonhealing facial ulcer with corneal ulceration.
    The British journal of dermatology, 2019, Volume: 181, Issue:1

    Topics: Analgesics; Brain Infarction; Corneal Diseases; Facial Dermatoses; Female; Gabapentin; Humans; Medul

2019
Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:7

    Topics: Amines; Animals; Anticonvulsants; Brain; Brain Infarction; Brain Ischemia; Cortical Spreading Depres

2011
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarbo

2004