Page last updated: 2024-10-27

gabapentin and Bone Neoplasms

gabapentin has been researched along with Bone Neoplasms in 11 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.

Research Excerpts

ExcerptRelevanceReference
"A rat model of cancer-induced bone pain using the MRMT-1 cell line injected into the tibia was established to investigate the efficacy of acute (10, 30, 100 mg/kg) and chronic (30 mg/kg) systemic gabapentin on electrophysiological superficial dorsal horn neuronal responses to natural and noxious electrical stimuli, as well as on pain-related behavior."7.73Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. ( Dickenson, AH; Donovan-Rodriguez, T; Urch, CE, 2005)
" Based on the need for new approaches in that field the effect of systemic administration of lacosamide (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037), a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsive drug candidates, was examined in rats in a tumor-induced bone cancer pain model and in a chemotherapy-induced neuropathic pain model."3.74Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain. ( Bain, SC; Beyreuther, BK; Brot, MD; Callizot, N; Feldman, R; Stöhr, T, 2007)
"A rat model of cancer-induced bone pain using the MRMT-1 cell line injected into the tibia was established to investigate the efficacy of acute (10, 30, 100 mg/kg) and chronic (30 mg/kg) systemic gabapentin on electrophysiological superficial dorsal horn neuronal responses to natural and noxious electrical stimuli, as well as on pain-related behavior."3.73Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. ( Dickenson, AH; Donovan-Rodriguez, T; Urch, CE, 2005)
"This severe pain is mostly refractory to palliative analgesic treatment, and the latter was only detected by specific and sensitive outcomes."2.87Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial. ( Beauchamp, G; Blair, J; de Lorimier, LP; Lussier, B; Monteiro, BP; Moreau, M; Pelletier, JP; Troncy, E, 2018)
"Delirium is still one of the most common and distressing symptoms in palliative care patients."1.38Reversible delirium in an advanced cancer patient. ( Jagsch, C; Kierner, KA; Watzke, HH, 2012)
"Gabapentin, which has been suggested as an adjuvant analgesic for neuropathic pain introduced orally, rapidly and significantly alleviated his pain and we could subsequently dispense with ketamine and mexiletine."1.34[Gabapentin mitigates neuropathic pain in cancer patients--a case report]. ( Okada, M; Shinjo, T, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corona-Ramos, JN1
Déciga-Campos, M1
Romero-Piña, M1
Medina, LA1
Martínez-Racine, I1
Jaramillo-Morales, OA1
García-López, P1
López-Muñoz, FJ1
Wang, X1
Yi, Y1
Tang, D1
Chen, Y1
Jiang, Y1
Peng, J1
Xiao, J1
Kendall, MC1
Castro-Alves, LJ1
Anghelescu, DL1
Pankayatselvan, V1
Nguyen, R1
Ward, D1
Wu, J1
Wu, H1
Edwards, DD1
Furman, W1
Monteiro, BP1
de Lorimier, LP1
Moreau, M1
Beauchamp, G1
Blair, J1
Lussier, B1
Pelletier, JP1
Troncy, E1
Caraceni, A1
Zecca, E1
Martini, C1
Pigni, A1
Bracchi, P1
Menéndez, L1
Hidalgo, A1
Meana, A1
Poras, H1
Fournié-Zaluski, MC1
Roques, BP1
Baamonde, A1
Kierner, KA1
Jagsch, C1
Watzke, HH1
Donovan-Rodriguez, T1
Dickenson, AH1
Urch, CE1
Beyreuther, BK1
Callizot, N1
Brot, MD1
Feldman, R1
Bain, SC1
Stöhr, T1
Okada, M1
Shinjo, T1

Trials

2 trials available for gabapentin and Bone Neoplasms

ArticleYear
Gabapentin as an Adjuvant Therapy for Prevention of Acute Phantom-Limb Pain in Pediatric Patients Undergoing Amputation for Malignant Bone Tumors: A Prospective Double-Blind Randomized Controlled Trial.
    Journal of pain and symptom management, 2018, Volume: 55, Issue:3

    Topics: Adolescent; Amputation, Surgical; Analgesics; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Double-

2018
Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Amitriptyline; Analgesics; Animals; Bone Neoplasms; Central Nervous System Sensitization; Dog Diseas

2018

Other Studies

9 other studies available for gabapentin and Bone Neoplasms

ArticleYear
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
    Drug development research, 2017, Volume: 78, Issue:5

    Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Su

2017
Gabapentin to Prevent Acute Phantom-Limb Pain in Pediatric Patients Undergoing Amputation.
    Journal of pain and symptom management, 2018, Volume: 56, Issue:2

    Topics: Amputation, Surgical; Bone Neoplasms; Child; Double-Blind Method; Gabapentin; Humans; Phantom Limb;

2018
Bisphosphonate Use in Pediatric Oncology for Pain Management.
    The American journal of hospice & palliative care, 2019, Volume: 36, Issue:2

    Topics: Administration, Oral; Adolescent; Age Factors; Age of Onset; Analgesics, Opioid; Bone Neoplasms; Can

2019
Gabapentin for breakthrough pain due to bone metastases.
    Palliative medicine, 2008, Volume: 22, Issue:4

    Topics: Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid

2008
Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin.
    European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3

    Topics: Administration, Oral; Amines; Analgesics; Animals; Bone Neoplasms; Cyclohexanecarboxylic Acids; Disu

2008
Reversible delirium in an advanced cancer patient.
    Wiener medizinische Wochenschrift (1946), 2012, Volume: 162, Issue:1-2

    Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, No

2012
Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain.
    Anesthesiology, 2005, Volume: 102, Issue:1

    Topics: Amines; Analgesics; Animals; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Cyclohexanecarboxyl

2005
Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain.
    European journal of pharmacology, 2007, Jun-22, Volume: 565, Issue:1-3

    Topics: Acetamides; Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cyclohex

2007
[Gabapentin mitigates neuropathic pain in cancer patients--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Adenocarcinoma; Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A

2007