Page last updated: 2024-10-27

gabapentin and Bladder Cancer

gabapentin has been researched along with Bladder Cancer in 2 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with gabapentin had no effect on the spread of sensory block or the regression of motor block but was associated with lower systolic arterial blood pressure values in patients undergoing subarachnoid anesthesia with ropivacaine."2.73Preoperative gabapentin: the effect on ropivacaine subarachnoid block and hemodynamics. ( Chatziara, V; Fassoulaki, A; Melemeni, A; Sarantopoulos, C; Zotou, M, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bala, I1
Bharti, N1
Chaubey, VK1
Mandal, AK1
Fassoulaki, A1
Chatziara, V1
Melemeni, A1
Zotou, M1
Sarantopoulos, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Preoperative Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion: a Double Blind, Randomized, Placebo Controlled Trial[NCT03151746]Phase 420 participants (Actual)Interventional2018-01-14Terminated (stopped due to Insufficient enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

24 Hour Pain Burden

Pain scores using an 11 point numeric pain rating scale 0=no pain 10 = worst pain imaginable (NCT03151746)
Timeframe: 24 hours after surgery

Interventionscore on a scale (Mean)
Placebo4.11
Gabapentin3.11

48 Hours Morphine Equivalents Consumed.

Total morphine equivalents in milligrams consumed during the first 48 hours after surgery. (NCT03151746)
Timeframe: Up to 48 hours after surgery

Interventionmorphine milligrams (Mean)
Placebo51.87
Gabapentin15.71

QOR 40 Questionnaire Scores

Evaluate quality of recovery using the Quality of Recovery 40 (QoR 40) questionnaire a 40 question survey scored from 40 ( poor recovery) to 200 high (good recovery) 48 hours after the surgical procedure. (NCT03151746)
Timeframe: 48 hours after surgical procedure

Interventionscore on a scale (Mean)
Placebo181.3
Gabapentin187.5

Trials

2 trials available for gabapentin and Bladder Cancer

ArticleYear
Efficacy of gabapentin for prevention of postoperative catheter-related bladder discomfort in patients undergoing transurethral resection of bladder tumor.
    Urology, 2012, Volume: 79, Issue:4

    Topics: Adult; Amines; Anticonvulsants; Catheters, Indwelling; Cyclohexanecarboxylic Acids; Double-Blind Met

2012
Preoperative gabapentin: the effect on ropivacaine subarachnoid block and hemodynamics.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:1

    Topics: Administration, Oral; Aged; Amides; Amines; Analgesics; Anesthetics, Local; Blood Pressure; Cyclohex

2008