gabapentin has been researched along with Bile Duct Obstruction in 5 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Excerpt | Relevance | Reference |
---|---|---|
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception." | 9.12 | Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006) |
"Combined spinal administration of gabapentin and low doses of morphine significantly reduces pain-related behaviors in this acute rat pancreatitis model, whereas these agents were ineffective when used alone in this dose range." | 7.72 | Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model. ( Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A, 2004) |
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception." | 5.12 | Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006) |
"Combined spinal administration of gabapentin and low doses of morphine significantly reduces pain-related behaviors in this acute rat pancreatitis model, whereas these agents were ineffective when used alone in this dose range." | 3.72 | Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model. ( Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Pongcharoen, P | 1 |
Fleischer, AB | 1 |
Anand, S | 1 |
Richardson, CE | 1 |
Williams, DW | 1 |
Kingham, JG | 1 |
Smiley, MM | 1 |
Lu, Y | 1 |
Vera-Portocarrero, LP | 1 |
Zidan, A | 1 |
Westlund, KN | 1 |
Bergasa, NV | 1 |
McGee, M | 1 |
Ginsburg, IH | 1 |
Engler, D | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Study of Gabapentin for the Pruritus of Cholestasis[NCT00058890] | Phase 3 | 15 participants (Actual) | Interventional | 2000-11-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for gabapentin and Bile Duct Obstruction
Article | Year |
---|---|
Itch Management: Systemic Agents.
Topics: Amines; Analgesics; Analgesics, Opioid; Anion Exchange Resins; Antidepressive Agents; Aprepitant; Ch | 2016 |
Gabapentin for pruritus in palliative care.
Topics: Amines; Analgesics, Opioid; Burns; Cholestasis; Cyclohexanecarboxylic Acids; Dermatologic Agents; Ga | 2013 |
1 trial available for gabapentin and Bile Duct Obstruction
Article | Year |
---|---|
Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Amines; Analgesics; Cholestasis; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind M | 2006 |
2 other studies available for gabapentin and Bile Duct Obstruction
Article | Year |
---|---|
Gabapentin induced cholestasis.
Topics: Acetates; Amines; Anticonvulsants; Cholestasis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; | 2002 |
Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.
Topics: Acetates; Acute Disease; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bradykin | 2004 |