Page last updated: 2024-10-27

gabapentin and Bile Duct Obstruction

gabapentin has been researched along with Bile Duct Obstruction in 5 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception."9.12Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006)
"Combined spinal administration of gabapentin and low doses of morphine significantly reduces pain-related behaviors in this acute rat pancreatitis model, whereas these agents were ineffective when used alone in this dose range."7.72Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model. ( Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A, 2004)
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception."5.12Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial. ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006)
"Combined spinal administration of gabapentin and low doses of morphine significantly reduces pain-related behaviors in this acute rat pancreatitis model, whereas these agents were ineffective when used alone in this dose range."3.72Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model. ( Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pongcharoen, P1
Fleischer, AB1
Anand, S1
Richardson, CE1
Williams, DW1
Kingham, JG1
Smiley, MM1
Lu, Y1
Vera-Portocarrero, LP1
Zidan, A1
Westlund, KN1
Bergasa, NV1
McGee, M1
Ginsburg, IH1
Engler, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Gabapentin for the Pruritus of Cholestasis[NCT00058890]Phase 315 participants (Actual)Interventional2000-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gabapentin and Bile Duct Obstruction

ArticleYear
Itch Management: Systemic Agents.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Amines; Analgesics; Analgesics, Opioid; Anion Exchange Resins; Antidepressive Agents; Aprepitant; Ch

2016
Gabapentin for pruritus in palliative care.
    The American journal of hospice & palliative care, 2013, Volume: 30, Issue:2

    Topics: Amines; Analgesics, Opioid; Burns; Cholestasis; Cyclohexanecarboxylic Acids; Dermatologic Agents; Ga

2013

Trials

1 trial available for gabapentin and Bile Duct Obstruction

ArticleYear
Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:5

    Topics: Adult; Amines; Analgesics; Cholestasis; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind M

2006

Other Studies

2 other studies available for gabapentin and Bile Duct Obstruction

ArticleYear
Gabapentin induced cholestasis.
    BMJ (Clinical research ed.), 2002, Sep-21, Volume: 325, Issue:7365

    Topics: Acetates; Amines; Anticonvulsants; Cholestasis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies;

2002
Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bradykin

2004