Page last updated: 2024-10-27

gabapentin and Behavior Disorders

gabapentin has been researched along with Behavior Disorders in 24 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
") and restless legs syndrome treated with ropinirole and gabapentin, will be discussed."4.89Recent advances in sleep research. ( Anderer, P; Saletu, B; Saletu-Zyhlarz, GM, 2013)
"Gabapentin appeared to be a safe and efficacious medication to reduce cocaine usage in a community sample of psychiatric patients."2.71Gabapentin reduces cocaine use among addicts from a community clinic sample. ( Coomaraswamy, S; Raby, WN, 2004)
"Pediatric epilepsy is a common, chronic, and challenging physical illness for children and their families."2.46Psychiatric concerns in pediatric epilepsy. ( Bujoreanu, IS; DeMaso, DR; Ibeziako, P, 2010)
"Gabapentin has been administered to several geriatric patients with bipolar disorder and patients with dementia."2.44Use of gabapentin in the treatment of behavioural and psychological symptoms of dementia: a review of the evidence. ( Kim, Y; Tampi, RR; Wilkins, KM, 2008)
" In the meantime, a review of the established pharmacokinetic and pharmacodynamic activities of these agents is the first step in defining their optimal uses and limitations in the psychiatric setting."2.40Pharmacokinetics of new anticonvulsants in psychiatry. ( Morris, HH, 1998)
"Cases with EoE with a psychiatric diagnosis were more likely to be women, white, and 18 years or older and to have a longer symptom duration before diagnosis."1.56Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation. ( Corder, SR; Dellon, ES; Eluri, S; Kim, E; Reed, CC; Sanders, E; Tappata, M, 2020)
"All patients had substance use disorders, the large majority (72 %) to more than one substance."1.43Abuse of Gabapentin is Associated with Opioid Addiction. ( Bastiaens, L; Galus, J; Mazur, C, 2016)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.67)18.2507
2000's13 (54.17)29.6817
2010's6 (25.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Reed, CC1
Corder, SR1
Kim, E1
Sanders, E1
Tappata, M1
Eluri, S1
Dellon, ES1
Ishida, JH1
McCulloch, CE1
Steinman, MA1
Grimes, BA1
Johansen, KL1
Amos, LB1
Grekowicz, ML1
Kuhn, EM1
Olstad, JD1
Collins, MM1
Norins, NA1
D'Andrea, LA1
Saletu, B1
Anderer, P1
Saletu-Zyhlarz, GM1
Bastiaens, L1
Galus, J1
Mazur, C1
Levy, BS1
Mansfield, AS1
Qian, Q1
Bujoreanu, IS1
Ibeziako, P1
DeMaso, DR1
Gibbons, RD1
Hur, K1
Brown, CH1
Mann, JJ1
Moretti, R1
Torre, P1
Antonello, RM1
Cazzato, G1
Bava, A1
Raby, WN1
Coomaraswamy, S1
Gálvez, R1
Marsal, C1
Vidal, J1
Ruiz, M1
Rejas, J1
Sommer, BR1
Fenn, HH1
Ketter, TA1
Kim, Y1
Wilkins, KM1
Tampi, RR1
Bras, M1
Ryback, R1
Ryback, L1
Chouinard, G1
Beauclair, L1
Bélanger, MC1
Dallocchio, C1
Buffa, C1
Mazzarello, P1
Alao, AO1
Dewan, MJ2
Bozikas, V1
Bascialla, F1
Yulis, P1
Savvidou, I1
Karavatos, A1
Megna, JL1
Devitt, PJ1
Sauro, MD1
Morris, HH1
Sussman, N1
Durkin, JP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Treatment of Sleep Bruxism With the Luco Hybrid OSA Appliance[NCT02882880]51 participants (Actual)Interventional2015-07-31Completed
Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776]Phase 254 participants (Actual)Interventional2017-08-07Completed
Effects of Transverse Abdominis Plane Block Guided by Ultrasound on the Postoperative Analgesia and Quality of Lives Among the Patients Undergo Inguinal Hernia Repair[NCT02292095]Phase 4260 participants (Anticipated)Interventional2016-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Prefrontal GABA+ Concentrations

Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine3.90
Gabapentin3.93
Placebo Oral Tablet3.73

Prefrontal Glx Concentrations

Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine21.59
Gabapentin21.69
Placebo Oral Tablet22.25

Reviews

8 reviews available for gabapentin and Behavior Disorders

ArticleYear
Recent advances in sleep research.
    Psychiatria Danubina, 2013, Volume: 25, Issue:4

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Amines; Antiparkinson Agents; Biomedical Research;

2013
The complex nature of chronic pelvic pain.
    The Journal of family practice, 2007, Volume: 56, Issue:3 Suppl Di

    Topics: Adult; Amines; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents,

2007
Psychiatric concerns in pediatric epilepsy.
    Child and adolescent psychiatric clinics of North America, 2010, Volume: 19, Issue:2

    Topics: Adolescent; Amines; Anxiety Disorders; Bipolar Disorder; Child; Child, Preschool; Cyclohexanecarboxy

2010
Safety and efficacy of anticonvulsants in elderly patients with psychiatric disorders: oxcarbazepine, topiramate and gabapentin.
    Expert opinion on drug safety, 2007, Volume: 6, Issue:2

    Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gam

2007
Use of gabapentin in the treatment of behavioural and psychological symptoms of dementia: a review of the evidence.
    Drugs & aging, 2008, Volume: 25, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Dementia,

2008
[Psychopharmacotherapy in psychiatric comorbidities among patients with chronic pain].
    L'Encephale, 2007, Volume: 33, Issue:Pt 3

    Topics: Amines; Analgesics; Anticonvulsants; Bupropion; Chronic Disease; Cyclohexanecarboxylic Acids; Dopami

2007
Pharmacokinetics of new anticonvulsants in psychiatry.
    Cleveland Clinic journal of medicine, 1998, Volume: 65 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructo

1998
Background and rationale for use of anticonvulsants in psychiatry.
    Cleveland Clinic journal of medicine, 1998, Volume: 65 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cycloh

1998

Trials

5 trials available for gabapentin and Behavior Disorders

ArticleYear
Gabapentin for the treatment of behavioural alterations in dementia: preliminary 15-month investigation.
    Drugs & aging, 2003, Volume: 20, Issue:14

    Topics: Acetates; Aged; Amines; Anti-Anxiety Agents; Comorbidity; Cyclohexanecarboxylic Acids; Dementia; Fem

2003
Gabapentin reduces cocaine use among addicts from a community clinic sample.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:1

    Topics: Acetates; Adult; Amines; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Diagnosis, Dual (Ps

2004
Cross-sectional evaluation of patient functioning and health-related quality of life in patients with neuropathic pain under standard care conditions.
    European journal of pain (London, England), 2007, Volume: 11, Issue:3

    Topics: Adult; Age Distribution; Aged; Amines; Analgesics; Cohort Studies; Cross-Sectional Studies; Cyclohex

2007
Gabapentin: long-term antianxiety and hypnotic effects in psychiatric patients with comorbid anxiety-related disorders.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:3

    Topics: Acetates; Adult; Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Behavioral S

1998
Gabapentin's effect on agitation in severely and persistently mentally ill patients.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:1

    Topics: Acetates; Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobuty

2002

Other Studies

11 other studies available for gabapentin and Behavior Disorders

ArticleYear
Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Anxiety Disorders; Benzodiazepines; Chest Pain; Child; Chronic

2020
Gabapentin and Pregabalin Use and Association with Adverse Outcomes among Hemodialysis Patients.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:7

    Topics: Accidental Falls; Aged; Analgesics; Emergency Service, Hospital; Female; Fractures, Bone; Gabapentin

2018
Treatment of pediatric restless legs syndrome.
    Clinical pediatrics, 2014, Volume: 53, Issue:4

    Topics: Adolescent; Amines; Analgesics; Anticonvulsants; Antioxidants; Benzothiazoles; Child; Child, Prescho

2014
Abuse of Gabapentin is Associated with Opioid Addiction.
    The Psychiatric quarterly, 2016, Volume: 87, Issue:4

    Topics: Adult; Amines; Attention Deficit Disorder with Hyperactivity; Comorbidity; Criminals; Cyclohexanecar

2016
71-year-old man with chronic kidney failure and sudden change of mental status.
    Mayo Clinic proceedings, 2009, Volume: 84, Issue:11

    Topics: Academic Medical Centers; Aged; Amines; Analgesics; Confusion; Cyclohexanecarboxylic Acids; Dose-Res

2009
Gabapentin and suicide attempts.
    Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:12

    Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin;

2010
Gabapentin for behavioral dyscontrol.
    The American journal of psychiatry, 1995, Volume: 152, Issue:9

    Topics: Acetates; Adolescent; Amines; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Cycloh

1995
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:1

    Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibi

2000
Evaluating the tolerability of the newer mood stabilizers.
    The Journal of nervous and mental disease, 2001, Volume: 189, Issue:1

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Central Nervous System Diseases; Cyclohexanecar

2001
Gabapentin for behavioral dyscontrol with mental retardation.
    The American journal of psychiatry, 2001, Volume: 158, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Drug Th

2001
Gabapentin in complicated school refusal.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:6

    Topics: Acetates; Adolescent; Amines; Comorbidity; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy,

2002