Page last updated: 2024-10-27

gabapentin and Atrophy

gabapentin has been researched along with Atrophy in 6 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"The aim of this work was to investigate the efficacy of the GABAergic drug gabapentin in the treatment of the cerebellar signs caused by cortical cerebellar atrophy (CCA)."9.11Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study. ( Benavente, I; Errea, JM; Gazulla, J; Tordesillas, CJ, 2004)
"No causal treatment of ataxias is available at the moment, and so symptomatic and disease-modifying therapies are regarded as a reliable possibility for this complex group of movement disorders."5.35Gabapentin treatment improves motor coordination in a mice model of progressive ataxia. ( Calzà, L; D'Intino, G; Ferraro, L; Giardino, L; Gusciglio, M; Massella, A; Sivilia, S, 2009)
"Acute seizure activity was behaviorally scored and hemispheric brain atrophy measured."5.35Gabapentin neuroprotection and seizure suppression in immature mouse brain ischemia. ( Comi, AM; Johnston, MV; Kadam, SD; Mulholland, JD; Traa, BS, 2008)
"The aim of this work was to investigate the efficacy of the GABAergic drug gabapentin in the treatment of the cerebellar signs caused by cortical cerebellar atrophy (CCA)."5.11Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study. ( Benavente, I; Errea, JM; Gazulla, J; Tordesillas, CJ, 2004)
" Therefore, in women with a uterus, it is recommended that physicians prescribe combination therapy only to treat menopausal symptoms such as vasomotor symptoms (hot flashes) and vaginal atrophy, using the smallest effective dosage for the shortest possible duration."2.53Hormone Therapy and Other Treatments for Symptoms of Menopause. ( Crider, M; Hill, DA; Hill, SR, 2016)
"No causal treatment of ataxias is available at the moment, and so symptomatic and disease-modifying therapies are regarded as a reliable possibility for this complex group of movement disorders."1.35Gabapentin treatment improves motor coordination in a mice model of progressive ataxia. ( Calzà, L; D'Intino, G; Ferraro, L; Giardino, L; Gusciglio, M; Massella, A; Sivilia, S, 2009)
"Acute seizure activity was behaviorally scored and hemispheric brain atrophy measured."1.35Gabapentin neuroprotection and seizure suppression in immature mouse brain ischemia. ( Comi, AM; Johnston, MV; Kadam, SD; Mulholland, JD; Traa, BS, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nascimento-Alves, P1
Fernandes-Silva, H1
Aragão-Homem, C1
Geraldes, R1
Fonseca, AC1
Hill, DA1
Crider, M1
Hill, SR1
Massella, A1
Gusciglio, M1
D'Intino, G1
Sivilia, S1
Ferraro, L1
Calzà, L1
Giardino, L1
Gazulla, J1
Errea, JM1
Benavente, I1
Tordesillas, CJ1
Horvath, J1
Coeytaux, A1
Jallon, P1
Landis, T1
Temperli, P1
Burkhard, PR1
Traa, BS1
Mulholland, JD1
Kadam, SD1
Johnston, MV1
Comi, AM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Effects of Clinical Pilates Training and Aerobic Exercise on Menopausal Symptoms, Quality of Life, Sleep and Depression[NCT05764031]30 participants (Actual)Interventional2020-12-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gabapentin and Atrophy

ArticleYear
Hormone Therapy and Other Treatments for Symptoms of Menopause.
    American family physician, 2016, Dec-01, Volume: 94, Issue:11

    Topics: Acupuncture Therapy; Administration, Intravaginal; Amines; Antidepressive Agents; Atrophy; Cyclohexa

2016

Trials

1 trial available for gabapentin and Atrophy

ArticleYear
Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study.
    European neurology, 2004, Volume: 52, Issue:1

    Topics: Acetates; Aged; Amines; Antiparkinson Agents; Atrophy; Cerebellar Ataxia; Cerebellar Cortex; Cyclohe

2004

Other Studies

4 other studies available for gabapentin and Atrophy

ArticleYear
IV and V cranial nerves dysfunction as initial manifestations of superficial siderosis of the central nervous system.
    Revista de neurologia, 2016, Apr-01, Volume: 62, Issue:7

    Topics: Aged; Amines; Angiography, Digital Subtraction; Atrophy; Central Nervous System Diseases; Cerebellum

2016
Gabapentin treatment improves motor coordination in a mice model of progressive ataxia.
    Brain research, 2009, Dec-08, Volume: 1301

    Topics: Age Factors; Amines; Analysis of Variance; Animals; Ataxia; Atrophy; Cell Count; Cerebellum; Chromat

2009
Carbamazepine encephalopathy masquerading as Creutzfeldt-Jakob disease.
    Neurology, 2005, Aug-23, Volume: 65, Issue:4

    Topics: Aged; Amines; Analgesics, Non-Narcotic; Atrophy; Basal Ganglia; Brain; Brain Damage, Chronic; Carbam

2005
Gabapentin neuroprotection and seizure suppression in immature mouse brain ischemia.
    Pediatric research, 2008, Volume: 64, Issue:1

    Topics: Amines; Animals; Animals, Newborn; Anticonvulsants; Atrophy; Behavior, Animal; Body Temperature; Bra

2008