gabapentin has been researched along with Ataxia in 13 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to compare the efficacy and tolerability of gabapentin and amitriptyline monotherapy in painful diabetic neuropathy." | 9.09 | Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study. ( Buffa, C; Chiroli, S; Dallocchio, C; Mazzarello, P, 2000) |
| "The aim of this study was to report relief of optokinetic-triggered vertigo (OKTV) with low-dose gabapentin in three patients with periodic vestibulocerebellar ataxia [episodic ataxia type 4 (EA4); OMIM 606552]." | 8.02 | Gabapentin Relieves Vertigo of Periodic Vestibulocerebellar Ataxia: 3 Cases and Possible Mechanism. ( Coin, JT; Vance, JM, 2021) |
| "No causal treatment of ataxias is available at the moment, and so symptomatic and disease-modifying therapies are regarded as a reliable possibility for this complex group of movement disorders." | 5.35 | Gabapentin treatment improves motor coordination in a mice model of progressive ataxia. ( Calzà, L; D'Intino, G; Ferraro, L; Giardino, L; Gusciglio, M; Massella, A; Sivilia, S, 2009) |
| "The objective of this study was to compare the efficacy and tolerability of gabapentin and amitriptyline monotherapy in painful diabetic neuropathy." | 5.09 | Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study. ( Buffa, C; Chiroli, S; Dallocchio, C; Mazzarello, P, 2000) |
| "The aim of this study was to report relief of optokinetic-triggered vertigo (OKTV) with low-dose gabapentin in three patients with periodic vestibulocerebellar ataxia [episodic ataxia type 4 (EA4); OMIM 606552]." | 4.02 | Gabapentin Relieves Vertigo of Periodic Vestibulocerebellar Ataxia: 3 Cases and Possible Mechanism. ( Coin, JT; Vance, JM, 2021) |
| "Thirty patients were enrolled: 10 on gabapentin, 10 on lamotrigine and 10 on carbamazepine monotherapy for epilepsy." | 3.73 | Measuring the effects of antiepileptic medications on balance in older people. ( Blum, D; Fife, TD; Fisher, RS, 2006) |
| "No causal treatment of ataxias is available at the moment, and so symptomatic and disease-modifying therapies are regarded as a reliable possibility for this complex group of movement disorders." | 1.35 | Gabapentin treatment improves motor coordination in a mice model of progressive ataxia. ( Calzà, L; D'Intino, G; Ferraro, L; Giardino, L; Gusciglio, M; Massella, A; Sivilia, S, 2009) |
| "In contrast, analgesia, sedation and catalepsy were not observed in this dose range, but were apparent at 100 mg/kg." | 1.33 | Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. ( Boulet, JM; Chaffer, SM; Elsemore, DA; Gottshall, SL; Harrison, JE; Koetzner, L; Lee, G; Mark, L; Miller, W; Pearson, MS; Rabadi, L; Rotshteyn, Y; Shan, S; Tafesse, L; Toth, M; Turchin, PI; Valenzano, KJ; Whiteside, GT, 2005) |
| "ent/ent mice develop ataxia by postnatal day 13-15, followed by paroxysmal dyskinesia a few days later." | 1.32 | entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse. ( Becker, CM; Becker, K; Boison, D; Brill, J; Gouder, N; Hofmann, F; Klocke, R; Klugbauer, N; Paul, D, 2004) |
| "Disappearance of the myokymia and improvement in the ataxia were attained with the use of the GABAergic drugs gabapentin and tiagabine." | 1.31 | [Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs]. ( Benavente Aguilar, I; Gazulla Abío, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Kharasch, ED | 1 |
| Clark, JD | 1 |
| Kheterpal, S | 1 |
| Coin, JT | 2 |
| Vance, JM | 2 |
| Gazulla, J | 1 |
| Androsova, G | 1 |
| Krause, R | 1 |
| Borghei, M | 1 |
| Wassenaar, M | 1 |
| Auce, P | 1 |
| Avbersek, A | 1 |
| Becker, F | 1 |
| Berghuis, B | 1 |
| Campbell, E | 1 |
| Coppola, A | 1 |
| Francis, B | 1 |
| Wolking, S | 1 |
| Cavalleri, GL | 1 |
| Craig, J | 1 |
| Delanty, N | 1 |
| Koeleman, BPC | 1 |
| Kunz, WS | 1 |
| Lerche, H | 1 |
| Marson, AG | 1 |
| Sander, JW | 1 |
| Sills, GJ | 1 |
| Striano, P | 1 |
| Zara, F | 1 |
| Sisodiya, SM | 1 |
| Depondt, C | 1 |
| Massella, A | 1 |
| Gusciglio, M | 1 |
| D'Intino, G | 1 |
| Sivilia, S | 1 |
| Ferraro, L | 1 |
| Calzà, L | 1 |
| Giardino, L | 1 |
| Brill, J | 1 |
| Klocke, R | 1 |
| Paul, D | 1 |
| Boison, D | 1 |
| Gouder, N | 1 |
| Klugbauer, N | 1 |
| Hofmann, F | 1 |
| Becker, CM | 1 |
| Becker, K | 1 |
| Spira, PJ | 1 |
| Beran, RG | 1 |
| Valenzano, KJ | 1 |
| Tafesse, L | 1 |
| Lee, G | 1 |
| Harrison, JE | 1 |
| Boulet, JM | 1 |
| Gottshall, SL | 1 |
| Mark, L | 1 |
| Pearson, MS | 1 |
| Miller, W | 1 |
| Shan, S | 1 |
| Rabadi, L | 1 |
| Rotshteyn, Y | 1 |
| Chaffer, SM | 1 |
| Turchin, PI | 1 |
| Elsemore, DA | 1 |
| Toth, M | 1 |
| Koetzner, L | 1 |
| Whiteside, GT | 1 |
| Fife, TD | 1 |
| Blum, D | 1 |
| Fisher, RS | 1 |
| Watson, WP | 1 |
| Robinson, E | 1 |
| Little, HJ | 1 |
| Dallocchio, C | 1 |
| Buffa, C | 1 |
| Mazzarello, P | 1 |
| Chiroli, S | 1 |
| Gazulla Abío, J | 1 |
| Benavente Aguilar, I | 1 |
2 trials available for gabapentin and Ataxia
| Article | Year |
|---|---|
Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebo-controlled study.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Ataxia; Chronic Disease; Cro | 2003 |
Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Ataxia; Cyclohexanecarboxylic | 2000 |
11 other studies available for gabapentin and Ataxia
| Article | Year |
|---|---|
Perioperative Gabapentinoids: Deflating the Bubble.
Topics: Analgesics; Ataxia; Dizziness; Gabapentin; Humans; Pain, Postoperative; Pregabalin; Preoperative Car | 2020 |
Gabapentin Relieves Vertigo of Periodic Vestibulocerebellar Ataxia: 3 Cases and Possible Mechanism.
Topics: Ataxia; Gabapentin; Humans; Nystagmus, Pathologic; Vertigo | 2021 |
Gabapentin Relieves Vertigo of Periodic Vestibulocerebellar Ataxia: 3 Cases and Possible Mechanism.
Topics: Ataxia; Gabapentin; Humans; Vertigo | 2021 |
Reply to: Gabapentin Relieves Vertigo of Periodic Vestibulocerebellar Ataxia: 3 Cases and Possible Mechanism.
Topics: Ataxia; Gabapentin; Humans; Vertigo | 2021 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; | 2017 |
Gabapentin treatment improves motor coordination in a mice model of progressive ataxia.
Topics: Age Factors; Amines; Analysis of Variance; Animals; Ataxia; Atrophy; Cell Count; Cerebellum; Chromat | 2009 |
entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse.
Topics: Acetates; Alleles; Amines; Animals; Ataxia; Base Sequence; Blotting, Southern; Blotting, Western; Ca | 2004 |
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Ataxia; Behavior, Ani | 2005 |
Measuring the effects of antiepileptic medications on balance in older people.
Topics: Aged; Amines; Anticonvulsants; Ataxia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Epilep | 2006 |
The novel anticonvulsant, gabapentin, protects against both convulsant and anxiogenic aspects of the ethanol withdrawal syndrome.
Topics: Acetates; Amines; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Cyclohexanecarboxylic Acids; E | 1997 |
[Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs].
Topics: Acetates; Adult; Amines; Ataxia; beta-N-Acetylhexosaminidases; Cerebellum; Cyclohexanecarboxylic Aci | 2002 |