Page last updated: 2024-10-27

gabapentin and Anxiety Disorders

gabapentin has been researched along with Anxiety Disorders in 16 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Anxiety Disorders: Persistent and disabling ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"We will include all randomised controlled trials (RCTs) reported as double-blind and comparing gabapentin or pregabalin with placebo or any other active pharmacological treatment (any preparation, dose, frequency, route of delivery or setting) in patients with bipolar disorder, anxiety or insomnia."8.95Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis. ( Atkinson, LZ; Awad, A; Cipriani, A; Forrest, A; Geddes, JR; Harrison, PJ; Houghton, KT; Stockton, S, 2017)
"We evaluated effectiveness and predictors of response of gabapentin (GBP) as adjunctive treatment in a sample of 43 subjects with DSM-III-R bipolar disorder who were resistant to standard mood stabilizers."7.71Effectiveness of adjunctive gabapentin in resistant bipolar disorder: is it due to anxious-alcohol abuse comorbidity? ( Akiskal, HS; Frare, F; Moretti, L; Perugi, G; Ruffolo, G; Toni, C; Torti, C, 2002)
"We will include all randomised controlled trials (RCTs) reported as double-blind and comparing gabapentin or pregabalin with placebo or any other active pharmacological treatment (any preparation, dose, frequency, route of delivery or setting) in patients with bipolar disorder, anxiety or insomnia."4.95Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis. ( Atkinson, LZ; Awad, A; Cipriani, A; Forrest, A; Geddes, JR; Harrison, PJ; Houghton, KT; Stockton, S, 2017)
"We evaluated effectiveness and predictors of response of gabapentin (GBP) as adjunctive treatment in a sample of 43 subjects with DSM-III-R bipolar disorder who were resistant to standard mood stabilizers."3.71Effectiveness of adjunctive gabapentin in resistant bipolar disorder: is it due to anxious-alcohol abuse comorbidity? ( Akiskal, HS; Frare, F; Moretti, L; Perugi, G; Ruffolo, G; Toni, C; Torti, C, 2002)
"Forty adult patients with partial epilepsy were studied in a prospective, non-randomized fashion with interviewer-rated and self-rated scales of mood and anxiety: the Cornell Dysthymia Rating Scale (CDRS), Beck Depression Inventory (BDI), and Hamilton Depression (Ham-D) and Anxiety (Ham-A) Scales."2.69A beneficial effect on mood in partial epilepsy patients treated with gabapentin. ( Carson, D; Goldstein, MA; Harden, CL; Kocsis, JH; Labar, DR; Lazar, LM; Nikolov, B; Pick, LH; Ravdin, LD, 1999)
"This review aims to analyze pharmacokinetic profile, plasma level variations so as the metabolism, interactions and possible relation to clinical effect of several drugs which are used primarily as anxiolytics."2.49Understanding the pharmacokinetics of anxiolytic drugs. ( Altamura, AC; Bareggi, S; Maffini, M; Mauri, MC; Moliterno, D; Paletta, S, 2013)
"Pediatric epilepsy is a common, chronic, and challenging physical illness for children and their families."2.46Psychiatric concerns in pediatric epilepsy. ( Bujoreanu, IS; DeMaso, DR; Ibeziako, P, 2010)
"Cases with EoE with a psychiatric diagnosis were more likely to be women, white, and 18 years or older and to have a longer symptom duration before diagnosis."1.56Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation. ( Corder, SR; Dellon, ES; Eluri, S; Kim, E; Reed, CC; Sanders, E; Tappata, M, 2020)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's6 (37.50)29.6817
2010's5 (31.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Mocanu, V1
Wood, E1
Reed, CC1
Corder, SR1
Kim, E1
Sanders, E1
Tappata, M1
Eluri, S1
Dellon, ES1
Houghton, KT1
Forrest, A1
Awad, A1
Atkinson, LZ1
Stockton, S1
Harrison, PJ1
Geddes, JR1
Cipriani, A1
Greenblatt, HK1
Greenblatt, DJ1
Bujoreanu, IS1
Ibeziako, P1
DeMaso, DR1
Steiger, A1
Altamura, AC1
Moliterno, D1
Paletta, S1
Maffini, M1
Mauri, MC1
Bareggi, S1
Perugi, G1
Toni, C1
Frare, F1
Ruffolo, G1
Moretti, L1
Torti, C1
Akiskal, HS1
Lydiard, RB1
Blanco, C1
Schneier, FR1
Schmidt, A1
Blanco-Jerez, CR1
Marshall, RD1
Sánchez-Lacay, A1
Liebowitz, MR1
Stahl, SM1
Kaufman, KR1
Hasnie, FS1
Breuer, J1
Parker, S1
Wallace, V1
Blackbeard, J1
Lever, I1
Kinchington, PR1
Dickenson, AH1
Pheby, T1
Rice, AS1
Chouinard, G1
Beauclair, L1
Bélanger, MC1
Pollack, MH1
Matthews, J1
Scott, EL1
Harden, CL1
Lazar, LM1
Pick, LH1
Nikolov, B1
Goldstein, MA1
Carson, D1
Ravdin, LD1
Kocsis, JH1
Labar, DR1

Reviews

6 reviews available for gabapentin and Anxiety Disorders

ArticleYear
Alcohol use disorder with comorbid anxiety disorder: a case report and focused literature review.
    Addiction science & clinical practice, 2022, 11-08, Volume: 17, Issue:1

    Topics: Alcoholism; Anxiety; Anxiety Disorders; Comorbidity; Gabapentin; Humans; Male; Middle Aged; Randomiz

2022
Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis.
    BMJ open, 2017, 03-27, Volume: 7, Issue:3

    Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Bipolar Disorder; Cyclohexanecarboxylic Acids; Doubl

2017
Psychiatric concerns in pediatric epilepsy.
    Child and adolescent psychiatric clinics of North America, 2010, Volume: 19, Issue:2

    Topics: Adolescent; Amines; Anxiety Disorders; Bipolar Disorder; Child; Child, Preschool; Cyclohexanecarboxy

2010
Understanding the pharmacokinetics of anxiolytic drugs.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Atenol

2013
The role of GABA in anxiety disorders.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 3

    Topics: Acetates; Amines; Anxiety Disorders; Benzodiazepines; Cyclohexanecarboxylic Acids; GABA Agents; Gaba

2003
Pharmacological treatment of social anxiety disorder: a meta-analysis.
    Depression and anxiety, 2003, Volume: 18, Issue:1

    Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agents; Anxiety Disorders; C

2003

Trials

2 trials available for gabapentin and Anxiety Disorders

ArticleYear
Gabapentin: long-term antianxiety and hypnotic effects in psychiatric patients with comorbid anxiety-related disorders.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:3

    Topics: Acetates; Adult; Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Behavioral S

1998
A beneficial effect on mood in partial epilepsy patients treated with gabapentin.
    Epilepsia, 1999, Volume: 40, Issue:8

    Topics: Acetates; Adult; Affect; Aged; Amines; Anticonvulsants; Anxiety Disorders; Comorbidity; Cyclohexanec

1999

Other Studies

8 other studies available for gabapentin and Anxiety Disorders

ArticleYear
Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Anxiety Disorders; Benzodiazepines; Chest Pain; Child; Chronic

2020
Gabapentin and Pregabalin for the Treatment of Anxiety Disorders.
    Clinical pharmacology in drug development, 2018, Volume: 7, Issue:3

    Topics: Anti-Anxiety Agents; Anxiety Disorders; GABA Agents; Gabapentin; Humans; Pregabalin; Treatment Outco

2018
Statement of the AGNP in the Context of the Planned Formation of a Fixed Reference Price Group "GABA-Analogues", November 21, 2011.
    Pharmacopsychiatry, 2012, Volume: 45, Issue:2

    Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Amino

2012
Effectiveness of adjunctive gabapentin in resistant bipolar disorder: is it due to anxious-alcohol abuse comorbidity?
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:6

    Topics: Acetates; Adult; Aged; Alcoholism; Amines; Anticonvulsants; Antimanic Agents; Anxiety Disorders; Bip

2002
Anticonvulsants as anxiolytics, part 2: Pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:4

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Calcium Channels; Cyclohe

2004
Monotherapy treatment of paruresis with gabapentin.
    International clinical psychopharmacology, 2005, Volume: 20, Issue:1

    Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relations

2005
Further characterization of a rat model of varicella zoster virus-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs.
    Neuroscience, 2007, Feb-23, Volume: 144, Issue:4

    Topics: Amines; Analgesics; Animals; Anti-Anxiety Agents; Anxiety Disorders; Cells, Cultured; Cyclohexanecar

2007
Gabapentin as a potential treatment for anxiety disorders.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids

1998