gabapentin has been researched along with Anesthesia in 15 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
Excerpt | Relevance | Reference |
---|---|---|
" After standard premedication, 25 patients in each group received propofol, fentanyl, and local anesthesia at the operative site." | 9.11 | The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Turan, A; Yağiz, R; Yavuz, E, 2004) |
"Further study of gabapentin and postoperative pain is needed employing rigorous and robust methodology and diversity of the sample selections." | 6.82 | Opioid-Sparing Anesthesia: Gabapentin and Postoperative Pain. ( Ladich, EM; Moore, CB; Spence, DL; Zhou, KQ, 2022) |
"There are no sufficient evidences for the sedative effect of gabapentin during anesthesia, especially intravenous sedation (IVS)." | 5.27 | Effectiveness of preanesthetic administration of gabapentin on sedative action during intravenous sedation with propofol. ( Hirokawa, J; Hosokawa, R; Ito, S; Oshima, Y; Yokoyama, T, 2018) |
"Patients undergoing craniotomy received either placebo (group D) or gabapentin (600 mg) (group GD) premedication orally, 2 hours before induction of anesthesia." | 5.17 | The effect of gabapentin premedication on postoperative nausea, vomiting, and pain in patients on preoperative dexamethasone undergoing craniotomy for intracranial tumors. ( Misra, S; Parthasarathi, G; Vilanilam, GC, 2013) |
" After standard premedication, 25 patients in each group received propofol, fentanyl, and local anesthesia at the operative site." | 5.11 | The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Turan, A; Yağiz, R; Yavuz, E, 2004) |
"Further study of gabapentin and postoperative pain is needed employing rigorous and robust methodology and diversity of the sample selections." | 2.82 | Opioid-Sparing Anesthesia: Gabapentin and Postoperative Pain. ( Ladich, EM; Moore, CB; Spence, DL; Zhou, KQ, 2022) |
"Gabapentin was administered IV (4 mg/kg) or orally (10 mg/kg) in a crossover randomized design." | 1.36 | Pharmacokinetics of gabapentin in cats. ( Ilkiw, JE; Pypendop, BH; Siao, KT, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (26.67) | 29.6817 |
2010's | 9 (60.00) | 24.3611 |
2020's | 2 (13.33) | 2.80 |
Authors | Studies |
---|---|
Ladich, EM | 1 |
Zhou, KQ | 1 |
Spence, DL | 1 |
Moore, CB | 1 |
Zetlaoui, PJ | 1 |
Pesche, L | 1 |
Benhamou, D | 1 |
Martinez, V | 1 |
Carles, M | 1 |
Marret, E | 1 |
Beloeil, H | 1 |
Hosokawa, R | 1 |
Ito, S | 1 |
Hirokawa, J | 1 |
Oshima, Y | 1 |
Yokoyama, T | 1 |
Hopkins, SC | 1 |
Zhao, FY | 1 |
Bowen, CA | 1 |
Fang, X | 1 |
Wei, H | 1 |
Heffernan, ML | 1 |
Spear, KL | 1 |
Spanswick, DC | 1 |
Varney, MA | 1 |
Large, TH | 1 |
Misra, S | 1 |
Parthasarathi, G | 1 |
Vilanilam, GC | 1 |
Chamaraux-Tran, TN | 1 |
Levy, F | 1 |
Zappaterra, M | 1 |
Goetz, J | 1 |
Goichot, B | 1 |
Steib, A | 1 |
Rashiq, S | 1 |
Dick, BD | 1 |
Crociolli, GC | 1 |
Cassu, RN | 1 |
Barbero, RC | 1 |
Rocha, TL | 1 |
Gomes, DR | 1 |
Nicácio, GM | 1 |
Hoffmann, U | 1 |
Dileköz, E | 1 |
Kudo, C | 1 |
Ayata, C | 1 |
Siao, KT | 1 |
Pypendop, BH | 1 |
Ilkiw, JE | 1 |
Freye, E | 1 |
Levy, JV | 1 |
Partecke, L | 1 |
Turan, A | 2 |
Memiş, D | 2 |
Karamanlioğlu, B | 2 |
Yağiz, R | 1 |
Pamukçu, Z | 1 |
Yavuz, E | 1 |
Seker, S | 1 |
Türe, M | 1 |
Chizh, BA | 1 |
Scheede, M | 1 |
Schlütz, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903] | Phase 4 | 77 participants (Actual) | Interventional | 2018-05-15 | Completed | ||
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty[NCT03498261] | Phase 1 | 50 participants (Actual) | Interventional | 2018-01-30 | Active, not recruiting | ||
Efficacy of Preoperative Administration of Gabapentin in Managing Intraoperative and Postoperative Pain From Third Molar Extractions.[NCT04860141] | Phase 4 | 98 participants (Anticipated) | Interventional | 2021-06-16 | Recruiting | ||
Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
Effect of Preoperative Pregabalin on Propofol Induction Dose[NCT01158859] | Phase 4 | 50 participants (Anticipated) | Interventional | 2010-04-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)
Intervention | score on 10-point scale (Mean) |
---|---|
Standard of Care | 2.26 |
Postoperative Gabapentin Regimen | 2.46 |
Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
Intervention | score on a 10-point scale (Mean) |
---|---|
Standard of Care | 3.84 |
Postoperative Gabapentin Regimen | 3.54 |
Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
Intervention | score on a 10-point scale (Mean) |
---|---|
Standard of Care | 5.73 |
Postoperative Gabapentin Regimen | 6.38 |
Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
Intervention | score on a 10-point scale (Mean) |
---|---|
Standard of Care | 0.36 |
Postoperative Gabapentin Regimen | 0.17 |
Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
Intervention | score on a 10-point scale (Mean) |
---|---|
Standard of Care | 7.83 |
Postoperative Gabapentin Regimen | 8.48 |
Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
Intervention | days (Mean) |
---|---|
Standard of Care | 14.8 |
Postoperative Gabapentin Regimen | 18.7 |
Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).
Intervention | morphine equivalents (Mean) |
---|---|
Standard of Care | 287.0 |
Postoperative Gabapentin Regimen | 281.1 |
2 reviews available for gabapentin and Anesthesia
Article | Year |
---|---|
Opioid-Sparing Anesthesia: Gabapentin and Postoperative Pain.
Topics: Analgesics; Analgesics, Opioid; Anesthesia; Gabapentin; Humans; Pain, Postoperative | 2022 |
Post-surgical pain syndromes: a review for the non-pain specialist.
Topics: Age Factors; Amines; Analgesics; Anesthesia; Anesthetics; Anesthetics, Local; Animals; Chronic Pain; | 2014 |
5 trials available for gabapentin and Anesthesia
Article | Year |
---|---|
Effectiveness of preanesthetic administration of gabapentin on sedative action during intravenous sedation with propofol.
Topics: Adult; Anesthesia; Conscious Sedation; Female; Gabapentin; Humans; Hypnotics and Sedatives; Male; Pr | 2018 |
The effect of gabapentin premedication on postoperative nausea, vomiting, and pain in patients on preoperative dexamethasone undergoing craniotomy for intracranial tumors.
Topics: Adult; Amines; Anesthesia; Anti-Inflammatory Agents; Brain Neoplasms; Craniotomy; Cyclohexanecarboxy | 2013 |
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
Gabapentin reduces cardiovascular responses to laryngoscopy and tracheal intubation.
Topics: Administration, Oral; Adult; Amines; Anesthesia; Blood Pressure; Cardiovascular Surgical Procedures; | 2006 |
8 other studies available for gabapentin and Anesthesia
Article | Year |
---|---|
Do we still need gabapentinoids in anaesthesia?
Topics: Anesthesia; Gabapentin; Humans; Pregabalin | 2021 |
Perioperative use of gabapentinoids in France. Mismatch between clinical practice and scientific evidence.
Topics: Anesthesia; Drug Prescriptions; Drug Utilization; Evidence-Based Medicine; Excitatory Amino Acid Ant | 2018 |
Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain.
Topics: Amines; Analgesics; Anesthesia; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarb | 2013 |
Cardiac surgery and C1-inhibitor deficiency.
Topics: Aged, 80 and over; Amines; Analgesics; Anesthesia; Angioedemas, Hereditary; Antifibrinolytic Agents; | 2014 |
Gabapentin as an adjuvant for postoperative pain management in dogs undergoing mastectomy.
Topics: Adjuvants, Anesthesia; Amines; Analgesics; Analgesics, Opioid; Anesthesia; Animals; Cyclohexanecarbo | 2015 |
Gabapentin suppresses cortical spreading depression susceptibility.
Topics: Amines; Anesthesia; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cortical Spreading | 2010 |
Pharmacokinetics of gabapentin in cats.
Topics: Administration, Oral; Amines; Anesthesia; Animals; Anticonvulsants; Cats; Cyclohexanecarboxylic Acid | 2010 |
Antinociception and (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid antagonism by gabapentin in the rat spinal cord in vivo.
Topics: Acetates; Amines; Analgesics; Anesthesia; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Dose-Re | 2000 |