Page last updated: 2024-10-27

gabapentin and Addiction, Opioid

gabapentin has been researched along with Addiction, Opioid in 42 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
" The patients who received intrathecal morphine and gabapentin also experienced a lower rate of nausea/vomiting and pruritus."9.41Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis. ( Caird, MS; Hong, RA; Leis, A; Li, Y; Robbins, C; Swallow, J, 2021)
"From December 2012 to February 2019, 682 hospitalizations for posterior spinal fusion in adolescent idiopathic scoliosis were identified with complete inpatient data; 49% were administered gabapentin."8.31Effect of gabapentin on length of stay, opioid use, and pain scores in posterior spinal fusion for adolescent idiopathic scoliosis: a retrospective review across a multi-hospital system. ( Brenn, B; Cho, R; Poon, SC; Samdani, A; Zhang, DA, 2023)
" The patients who received intrathecal morphine and gabapentin also experienced a lower rate of nausea/vomiting and pruritus."5.41Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis. ( Caird, MS; Hong, RA; Leis, A; Li, Y; Robbins, C; Swallow, J, 2021)
"From December 2012 to February 2019, 682 hospitalizations for posterior spinal fusion in adolescent idiopathic scoliosis were identified with complete inpatient data; 49% were administered gabapentin."4.31Effect of gabapentin on length of stay, opioid use, and pain scores in posterior spinal fusion for adolescent idiopathic scoliosis: a retrospective review across a multi-hospital system. ( Brenn, B; Cho, R; Poon, SC; Samdani, A; Zhang, DA, 2023)
"Gabapentin is commonly prescribed for chronic pain, including to patients with HIV (PWH)."4.12Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV. ( Barry, DT; Becker, WC; Crystal, S; Edelman, EJ; Gordon, KS; Kerns, RD; Li, Y; Marshall, BDL; Oldfield, BJ; Rentsch, CT; Vickers-Smith, R, 2022)
" The general population model included age, hepatitis C virus infection, days of opioid used by type, number of cigarettes used daily, and the following medications used in the last 30 day of pregnancy: bupropion, antinausea medicines, benzodiazepines, antipsychotics, and gabapentin."4.02Development and Validation of a Model to Predict Neonatal Abstinence Syndrome. ( Cooper, WO; Dudley, J; Harrell, FE; Hartmann, K; Martin, PR; Patrick, SW; Slaughter, JC; Stratton, S, 2021)
"Multiple approaches are needed to mitigate gabapentin misuse, including limiting availability in institutional settings and informal channels as well as addressing the needs of drug users who experience physical pain and withdrawal symptoms."3.91An ethnographic decision model of the initiation of gabapentin misuse among prescription and/or illicit opioid (mis)user. ( Buttram, ME; Cicero, TJ; Havens, JR; Kurtz, SP, 2019)
" When medically indicated, limiting use of multiple psychiatric medications, particularly benzodiazepines and gabapentin, during pregnancy should be considered to improve NAS outcomes."3.88Impact of psychiatric medication co-exposure on Neonatal Abstinence Syndrome severity. ( Nikita, FNU; Saia, K; Schiff, DM; Shaw, D; Shrestha, H; Thomas, Z; Thomas-Lewis, JA; Wachman, EM; Warden, AH, 2018)
"People who have co-occurring Alcohol Use Disorder (AUD) and Opioid Use Disorder (OUD) carry a higher risk of adverse outcomes, including drug overdose."3.11Gabapentin increases the abuse liability of alcohol alone and in combination with oxycodone in participants with co-occurring opioid and alcohol use disorder. ( Castillo, F; Comer, SD; Evans, SM; Foltin, RW; Jones, JD; Luba, RR; Mogali, S, 2022)
"Group A showed more withdrawal symptoms whereas the most common complain of group B was sedation particularly during the first three days."2.78The effects of gabapentin on methadone based addiction treatment: a randomized controlled trial. ( Alavinia, M; Moghadam, MS, 2013)
"Interestingly, opioids induce hyperalgesia via many of the same neuro-inflammatory and central sensitization processes that occur with the development of neuropathic pain."2.75Gabapentin improves cold-pressor pain responses in methadone-maintained patients. ( Compton, P; Kehoe, P; Ling, W; Sinha, K; Torrington, MA, 2010)
"Severity of subjective withdrawal symptoms using the Subjective Opiate Withdrawal Scale at six stages."2.73Effect of add-on gabapentin on opioid withdrawal symptoms in opium-dependent patients. ( Kheirabadi, GR; Maracy, MR; Ranjkesh, M; Salehi, M, 2008)
"However, it seems that opium withdrawal symptoms are significant, especially at days 2 to 4 after discontinuation of opium."2.58Pharmacological therapies for management of opium withdrawal. ( Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R, 2018)
"Gabapentin was removed from the protocol between 10/20/2020 and 12/31/2020 due to side effects; it was re-implemented on 1/1/2021 due to observed spikes in opioid use during its absence."1.91Effectiveness of Bariatric Surgery Targeting Opioid Prescriptions (BSTOP) protocol on postoperative pain control. ( Appiah, D; Camacho, D; Choi, J; Goriacko, P; Kim, J; Moran-Atkin, E; Pereira, X; Seu, R; Yaghdjian, V, 2023)
"He had a previous history of opioid use disorder (OUD) which has been in remission."1.91Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report. ( Jalilian Khave, L; Noori, M; Noroozi, A; Rahimi-Movaghar, A, 2023)
"0 % did so while also on a dosage of either buprenorphine or methadone, with 28."1.91Understanding motivations and use typologies of gabapentin with opioid agonist medications. ( Buttram, ME; Ellis, MS; Qureshi, R, 2023)
"Gabapentin was significantly less likely to be prescribed to Black or Hispanic patients, and more likely to be prescribed to female patients, those with co-occurring substance use or mood disorders, and those with comorbid physical conditions such as neuropathic pain."1.91Gabapentin Use Among Individuals Initiating Buprenorphine Treatment for Opioid Use Disorder. ( Buttram, ME; Ellis, MS; Fidalgo, TM; Grucza, RA; Tardelli, VS; Xu, KY, 2023)
"Gabapentin has been shown to reduce opioid use in head and neck cancer patients."1.72Effectiveness of gabapentin in reducing opioid requirements after radiation in head and neck cancer in a single institution. ( Biedermann, GB; Bollig, CA; Clark, AD; Dooley, LM; Gilley, DR; Wieser, ME, 2022)
"Younger age, male gender, neuropathic pain diagnosis and pregabalin use were significantly associated with higher levels of gabapentinoid misuse."1.62Prevalence of and Factors Associated with Gabapentinoid Use and Misuse Among Texas Medicaid Recipients. ( Barner, JC; Evoy, KE; Ibiloye, EA; Lawson, KA; Peckham, AM; Rascati, KL, 2021)
"Substance use is prevalent in Canada, yet treatment is inaccessible."1.56A rapid access to addiction medicine clinic facilitates treatment of substance use disorder and reduces substance use. ( Hulme, J; Sheikh, H; Wiercigroch, D, 2020)
"Persons with opioid use disorder (OUD) are at increased risk for gabapentin misuse."1.56Prescribed and non-prescribed gabapentin use among persons seeking inpatient opioid detoxification. ( Anderson, BJ; Bailey, GL; Conti, MT; Kenney, SR; Stein, MD, 2020)
"To evaluate the association between perioperative coadministration of gabapentinoids and opioids with inpatient opioid-related adverse events in surgical patients."1.56Association of Gabapentinoids With the Risk of Opioid-Related Adverse Events in Surgical Patients in the United States. ( Bateman, BT; Bykov, K; Franklin, JM; Patorno, E; Vine, SM, 2020)
"All patients had substance use disorders, the large majority (72 %) to more than one substance."1.43Abuse of Gabapentin is Associated with Opioid Addiction. ( Bastiaens, L; Galus, J; Mazur, C, 2016)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.38)18.2507
2000's1 (2.38)29.6817
2010's19 (45.24)24.3611
2020's21 (50.00)2.80

Authors

AuthorsStudies
Li, Y2
Swallow, J1
Robbins, C1
Caird, MS1
Leis, A1
Hong, RA1
Ellis, MS5
Buttram, ME6
Kasper, ZA1
Gilley, DR1
Clark, AD1
Wieser, ME1
Bollig, CA1
Dooley, LM1
Biedermann, GB1
Bongiovanni, T1
Gan, S1
Finlayson, E1
Ross, J1
Harrison, JD1
Boscardin, J1
Steinman, MA1
Kuehn, BM1
Seu, R1
Pereira, X1
Goriacko, P1
Yaghdjian, V1
Appiah, D1
Moran-Atkin, E1
Camacho, D1
Kim, J1
Choi, J1
Castillo, F1
Jones, JD1
Luba, RR1
Mogali, S1
Foltin, RW1
Evans, SM1
Comer, SD1
Jalilian Khave, L3
Noori, M3
Rahimi-Movaghar, A4
Noroozi, A3
Qureshi, R3
Zhang, DA1
Brenn, B1
Cho, R1
Samdani, A1
Poon, SC1
Xu, KY1
Tardelli, VS1
Fidalgo, TM1
Grucza, RA1
Gedda, C1
Nygren, J1
Garpenbeck, A1
Hoffström, L1
Thorell, A1
Soop, M1
de Dios, C1
Suchting, R1
Green, C1
Klugh, JM1
Harvin, JA1
Webber, HE1
Schmitz, JM1
Lane, SD1
Yoon, JH1
Heads, A1
Motley, K1
Stotts, A1
Tong, K1
Nolan, W1
O'Sullivan, DM1
Sheiner, P1
Kutzler, HL1
Murnion, BP1
Rivas, C1
Demirkol, A1
Hayes, V1
Lintzeris, N1
Nielsen, S1
Kurtz, SP1
Cicero, TJ1
Havens, JR2
Wiercigroch, D1
Sheikh, H1
Hulme, J1
Stein, MD1
Kenney, SR1
Anderson, BJ1
Conti, MT1
Bailey, GL1
Patrick, SW1
Slaughter, JC1
Harrell, FE1
Martin, PR1
Hartmann, K1
Dudley, J1
Stratton, S1
Cooper, WO1
Bykov, K1
Bateman, BT1
Franklin, JM1
Vine, SM1
Patorno, E1
Ibiloye, EA1
Barner, JC1
Lawson, KA1
Rascati, KL1
Evoy, KE2
Peckham, AM2
Zhang, Y1
Castracane, AR1
Winstanley, EL1
Oldfield, BJ1
Vickers-Smith, R1
Becker, WC1
Barry, DT1
Crystal, S1
Gordon, KS1
Kerns, RD1
Rentsch, CT1
Marshall, BDL1
Edelman, EJ1
Rudolf, G1
Walsh, J1
Plawman, A1
Gianutsos, P1
Alto, W1
Mancl, L1
Rudolf, V1
Oltman, J1
Militsakh, O1
D'Agostino, M1
Kauffman, B1
Lindau, R1
Coughlin, A1
Lydiatt, W1
Lydiatt, D1
Smith, R1
Panwar, A1
Covvey, JR1
Ochs, L1
Fairman, KA1
Sclar, DA1
Throckmorton, DC1
Gottlieb, S1
Woodcock, J1
Gholami, J1
Amato, L1
Hoseinie, L1
Yousefi-Nooraie, R1
Amin-Esmaeili, M1
Wachman, EM1
Warden, AH1
Thomas, Z1
Thomas-Lewis, JA1
Shrestha, H1
Nikita, FNU1
Shaw, D1
Saia, K1
Schiff, DM1
Gross, JL1
Perate, AR1
Elkassabany, NM1
Kim, S1
Sanders, NC1
Mancino, MJ1
Gentry, WB1
Guise, JB1
Bickel, WK1
Thostenson, J1
Oliveto, AH1
Moghadam, MS1
Alavinia, M1
Baird, CR1
Fox, P1
Colvin, LA1
Satish, R1
Kandasamy, A1
Jayarajan, D1
Benegal, V1
Smith, RV1
Lofwall, MR1
Bastiaens, L1
Galus, J1
Mazur, C1
Weinstein, ZM1
Cheng, DM1
Quinn, E1
Hui, D1
Kim, H1
Gryczynski, G1
Samet, JH1
Kheirabadi, GR2
Ranjkesh, M2
Maracy, MR2
Salehi, M2
Compton, P1
Kehoe, P1
Sinha, K1
Torrington, MA1
Ling, W1
Nicolodi, M1
Del Bianco, PL1
Sicuteri, F1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pragmatic, Multi-centre, Open-label, Randomized, 12-month, Parallel Group, Superiority Study to Compare the Effectiveness of Subcutaneous Buprenorphine Depot (Sublocade®) vs Daily Sublingual Buprenorphine With Naloxone (Suboxone®) for the Treatment of O[NCT05594121]Phase 490 participants (Anticipated)Interventional2022-12-31Not yet recruiting
Linking Opioid Dependent Patients From Inpatient Detoxification to Primary Care[NCT01751789]335 participants (Actual)Interventional2012-10-31Completed
Optimization of Opioid Discharge Prescriptions Following Thyroid and Parathyroid Surgeries[NCT04955444]240 participants (Actual)Interventional2021-06-14Completed
Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: a Prospective Study.[NCT05287217]60 participants (Anticipated)Interventional2022-07-29Not yet recruiting
Use of Single Dose Pre-Operative Pregabalin for Post-Operative Analgesia in Bilateral Head and Neck Cancer Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial[NCT03714867]Phase 40 participants (Actual)Interventional2019-03-22Withdrawn (stopped due to Inability to recruit patients)
Opioid-Induced Hyperalgesia in Prescription Opioid Abusers: Effects of Pregabalin[NCT01821430]Phase 24 participants (Actual)Interventional2013-03-31Terminated (stopped due to poor recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

New Opioid Discharge Prescriptions

Proportion of patients who receive new opioid discharge prescriptions at discharge following a thyroidectomy or parathyroidectomy procedure. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group128
Post-implementation Group28

New Opioid Prescriptions From the Surgeon's Office Within 7 Days of Surgery

Proportion of thyroidectomy and parathyroidectomy postoperative patients who receive new opioid prescriptions from the surgeon's office within 7 days of surgery including discharge prescriptions. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 7 days

InterventionParticipants (Count of Participants)
Historical Control Group0
Post-implementation Group0

Opioid Discharge Prescriptions Exceeding 112.5 Oral Morphine Milligram Equivalents (MMEs)

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding the recommended dose of 112.5 oral MMEs (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group52
Post-implementation Group8

Opioid Discharge Prescriptions Exceeding 5 Days

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding 5 days of therapy (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group27
Post-implementation Group5

Opioid Prescriptions Exceeding 50 Oral MMEs/Day When New Discharge Prescriptions Are Added to Existing Opioid Therapy

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid prescriptions exceeding 50 oral MMEs/day when new, postoperative discharge prescriptions are added to existing opioid therapy (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group9
Post-implementation Group0

Reviews

3 reviews available for gabapentin and Addiction, Opioid

ArticleYear
Pharmacological therapies for management of opium withdrawal.
    The Cochrane database of systematic reviews, 2018, 06-21, Volume: 6

    Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gam

2018
Pain Management in Trauma in the Age of the Opioid Crisis.
    Anesthesiology clinics, 2019, Volume: 37, Issue:1

    Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Gabapentin; Humans

2019
The unsuspected threat of three opioid-like substitutes.
    Archives of psychiatric nursing, 2019, Volume: 33, Issue:4

    Topics: Analgesics; Antidiarrheals; Gabapentin; Humans; Loperamide; Mitragyna; Opiate Substitution Treatment

2019

Trials

8 trials available for gabapentin and Addiction, Opioid

ArticleYear
Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis.
    Journal of orthopaedic surgery and research, 2021, Nov-15, Volume: 16, Issue:1

    Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Gabapentin; Humans; Kyphosis; Morphin

2021
Gabapentin increases the abuse liability of alcohol alone and in combination with oxycodone in participants with co-occurring opioid and alcohol use disorder.
    Pharmacology, biochemistry, and behavior, 2022, Volume: 221

    Topics: Alcoholism; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Ethanol; Gabapentin; Humans

2022
Acute Experimental Pain Responses in Methadone- and Buprenorphine/Naloxone-Maintained Patients Administered Additional Opioid or Gabapentin: A Double-Blind Crossover Pilot Study.
    Pain medicine (Malden, Mass.), 2020, 06-01, Volume: 21, Issue:6

    Topics: Analgesics, Opioid; Australia; Buprenorphine; Cross-Over Studies; Double-Blind Method; Gabapentin; H

2020
Randomized, placebo-controlled pilot trial of gabapentin during an outpatient, buprenorphine-assisted detoxification procedure.
    Experimental and clinical psychopharmacology, 2013, Volume: 21, Issue:4

    Topics: Adult; Amines; Buprenorphine; Cyclohexanecarboxylic Acids; Diagnostic and Statistical Manual of Ment

2013
The effects of gabapentin on methadone based addiction treatment: a randomized controlled trial.
    Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:5

    Topics: Adult; Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, C

2013
Effect of add-on gabapentin on opioid withdrawal symptoms in opium-dependent patients.
    Addiction (Abingdon, England), 2008, Volume: 103, Issue:9

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gam

2008
Gabapentin improves cold-pressor pain responses in methadone-maintained patients.
    Drug and alcohol dependence, 2010, Jun-01, Volume: 109, Issue:1-3

    Topics: Adult; Amines; Analgesics, Non-Narcotic; Cold Temperature; Cyclohexanecarboxylic Acids; Double-Blind

2010
Importance of gabapentin dose in treatment of opioid withdrawal.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:5

    Topics: Adult; Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relat

2011

Other Studies

31 other studies available for gabapentin and Addiction, Opioid

ArticleYear
Nonmedical use of gabapentin and opioid agonist medications in treatment-seeking individuals with opioid use disorder.
    Drug and alcohol dependence, 2022, 05-01, Volume: 234

    Topics: Analgesics, Opioid; Buprenorphine; Cross-Sectional Studies; Gabapentin; Humans; Methadone; Opiate Su

2022
Effectiveness of gabapentin in reducing opioid requirements after radiation in head and neck cancer in a single institution.
    Head & neck, 2022, Volume: 44, Issue:6

    Topics: Analgesics, Opioid; Gabapentin; Head and Neck Neoplasms; Humans; Opioid-Related Disorders; Retrospec

2022
Prolonged use of newly prescribed gabapentin after surgery.
    Journal of the American Geriatrics Society, 2022, Volume: 70, Issue:12

    Topics: Aged; Analgesics, Opioid; Female; Gabapentin; Humans; Male; Medicare; Opioid-Related Disorders; Pain

2022
Growing Role of Gabapentin in Opioid-Related Overdoses Highlights Misuse Potential and Off-label Prescribing Practices.
    JAMA, 2022, 10-04, Volume: 328, Issue:13

    Topics: Analgesics, Opioid; Central Nervous System Agents; Drug Overdose; Gabapentin; Humans; Off-Label Use;

2022
Effectiveness of Bariatric Surgery Targeting Opioid Prescriptions (BSTOP) protocol on postoperative pain control.
    Surgical endoscopy, 2023, Volume: 37, Issue:6

    Topics: Analgesics, Opioid; Bariatric Surgery; Gabapentin; Humans; Morphine; Opioid-Related Disorders; Pain,

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.
    Asian journal of psychiatry, 2023, Volume: 80

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Gabapentin; Humans; Male; Opioid-Related Disorders

2023
Understanding motivations and use typologies of gabapentin with opioid agonist medications.
    Drug and alcohol dependence, 2023, 01-01, Volume: 242

    Topics: Analgesics, Opioid; Buprenorphine; Cross-Sectional Studies; Gabapentin; Humans; Methadone; Motivatio

2023
Understanding motivations and use typologies of gabapentin with opioid agonist medications.
    Drug and alcohol dependence, 2023, 01-01, Volume: 242

    Topics: Analgesics, Opioid; Buprenorphine; Cross-Sectional Studies; Gabapentin; Humans; Methadone; Motivatio

2023
Understanding motivations and use typologies of gabapentin with opioid agonist medications.
    Drug and alcohol dependence, 2023, 01-01, Volume: 242

    Topics: Analgesics, Opioid; Buprenorphine; Cross-Sectional Studies; Gabapentin; Humans; Methadone; Motivatio

2023
Understanding motivations and use typologies of gabapentin with opioid agonist medications.
    Drug and alcohol dependence, 2023, 01-01, Volume: 242

    Topics: Analgesics, Opioid; Buprenorphine; Cross-Sectional Studies; Gabapentin; Humans; Methadone; Motivatio

2023
Effect of gabapentin on length of stay, opioid use, and pain scores in posterior spinal fusion for adolescent idiopathic scoliosis: a retrospective review across a multi-hospital system.
    BMC anesthesiology, 2023, 01-07, Volume: 23, Issue:1

    Topics: Adolescent; Analgesics, Opioid; Child; Gabapentin; Humans; Length of Stay; Multi-Institutional Syste

2023
Gabapentin Use Among Individuals Initiating Buprenorphine Treatment for Opioid Use Disorder.
    JAMA psychiatry, 2023, Dec-01, Volume: 80, Issue:12

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Case-Control Studies; Drug-Related Side Effects and Advers

2023
Multimodal Analgesia Bundle and Postoperative Opioid Use Among Patients Undergoing Colorectal Surgery.
    JAMA network open, 2023, 09-05, Volume: 6, Issue:9

    Topics: Agnosia; Analgesia; Analgesics, Opioid; Clonidine; Cohort Studies; Colorectal Surgery; Female; Gabap

2023
An opioid-minimizing multimodal pain regimen reduces opioid exposure and pain in trauma-injured patients at high risk for opioid misuse: Secondary analysis from the mast trial.
    Surgery, 2023, Volume: 174, Issue:6

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Bayes Theorem; Gabapentin; Humans; Morphine Derivativ

2023
Implementation of a Multimodal Pain Management Order Set Reduces Perioperative Opioid Use after Liver Transplantation.
    Pharmacotherapy, 2019, Volume: 39, Issue:10

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Drug Therapy, Combination; Female; Gabapentin;

2019
An ethnographic decision model of the initiation of gabapentin misuse among prescription and/or illicit opioid (mis)user.
    Drug and alcohol dependence, 2019, 11-01, Volume: 204

    Topics: Adult; Anthropology, Cultural; Decision Theory; Drug Users; Female; Gabapentin; Humans; Male; Opioid

2019
A rapid access to addiction medicine clinic facilitates treatment of substance use disorder and reduces substance use.
    Substance abuse treatment, prevention, and policy, 2020, 01-13, Volume: 15, Issue:1

    Topics: Acamprosate; Addiction Medicine; Adult; Aged; Alcohol Deterrents; Alcoholism; Buprenorphine; Emergen

2020
Prescribed and non-prescribed gabapentin use among persons seeking inpatient opioid detoxification.
    Journal of substance abuse treatment, 2020, Volume: 110

    Topics: Analgesics, Opioid; Drug Overdose; Female; Gabapentin; Humans; Inpatients; Male; Opioid-Related Diso

2020
Development and Validation of a Model to Predict Neonatal Abstinence Syndrome.
    The Journal of pediatrics, 2021, Volume: 229

    Topics: Adult; Analgesics; Antiemetics; Antipsychotic Agents; Benzodiazepines; Bupropion; Female; Gabapentin

2021
Association of Gabapentinoids With the Risk of Opioid-Related Adverse Events in Surgical Patients in the United States.
    JAMA network open, 2020, 12-01, Volume: 3, Issue:12

    Topics: Aged; Analgesics, Opioid; Drug Overdose; Drug Therapy, Combination; Female; Gabapentin; Humans; Male

2020
Prevalence of and Factors Associated with Gabapentinoid Use and Misuse Among Texas Medicaid Recipients.
    Clinical drug investigation, 2021, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Female; Gabapentin; Humans; Male; Medicaid; Middle Aged; Neur

2021
Assessment of gabapentin misuse using prescription drug monitoring program data.
    Substance abuse, 2021, Volume: 42, Issue:4

    Topics: Adult; Analgesics, Opioid; Gabapentin; Humans; Opioid-Related Disorders; Prescription Drug Misuse; P

2021
Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV.
    AIDS care, 2022, Volume: 34, Issue:8

    Topics: Analgesics, Opioid; Chronic Pain; Cohort Studies; Gabapentin; HIV Infections; Humans; Opioid-Related

2022
A novel non-opioid protocol for medically supervised opioid withdrawal and transition to antagonist treatment.
    The American journal of drug and alcohol abuse, 2018, Volume: 44, Issue:3

    Topics: Adult; Amines; Analgesics, Opioid; Buprenorphine; Clonidine; Counseling; Cyclohexanecarboxylic Acids

2018
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Predictors of Gabapentin Overuse With or Without Concomitant Opioids in a Commercially Insured U.S. Population.
    Pharmacotherapy, 2018, Volume: 38, Issue:4

    Topics: Age Factors; Analgesics, Opioid; Drug Utilization; Gabapentin; Humans; Hypnotics and Sedatives; Odds

2018
The FDA and the Next Wave of Drug Abuse - Proactive Pharmacovigilance.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Utilization

2018
Impact of psychiatric medication co-exposure on Neonatal Abstinence Syndrome severity.
    Drug and alcohol dependence, 2018, 11-01, Volume: 192

    Topics: Adult; Analgesics, Opioid; Benzodiazepines; Buprenorphine; Female; Gabapentin; Humans; Infant; Infan

2018
Gabapentinoid abuse in order to potentiate the effect of methadone: a survey among substance misusers.
    European addiction research, 2014, Volume: 20, Issue:3

    Topics: Amines; Behavior, Addictive; Cyclohexanecarboxylic Acids; Data Collection; Drug Synergism; Gabapenti

2014
Gabapentin dependence in a patient with opioid dependence syndrome.
    The Journal of neuropsychiatry and clinical neurosciences, 2015,Winter, Volume: 27, Issue:1

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans;

2015
Abuse and diversion of gabapentin among nonmedical prescription opioid users in Appalachian Kentucky.
    The American journal of psychiatry, 2015, Volume: 172, Issue:5

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid;

2015
Abuse of Gabapentin is Associated with Opioid Addiction.
    The Psychiatric quarterly, 2016, Volume: 87, Issue:4

    Topics: Adult; Amines; Attention Deficit Disorder with Hyperactivity; Comorbidity; Criminals; Cyclohexanecar

2016
Psychoactive medications and disengagement from office based opioid treatment (obot) with buprenorphine.
    Drug and alcohol dependence, 2017, Jan-01, Volume: 170

    Topics: Adult; Amines; Analgesics, Opioid; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Female; Ga

2017
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
    International journal of clinical pharmacology research, 1997, Volume: 17, Issue:2-3

    Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagon

1997